Publication date: Available online 24 September 2019Source: Behavioural Brain ResearchAuthor(s): Kennett D. Radford, Haley F. Spencer, Michael Zhang, Rina Y. Berman, Quinn L. Girasek, Kwang H. ChoiAbstractKetamine is a multimodal dissociative anesthetic and analgesic that is widely used after traumatic injury. We previously reported that an analgesic dose of intravenous (IV) ketamine infusion (10 mg/kg, 2-hr) after fear conditioning enhanced short-term fear memory in rats. Here, we investigated the...
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Publication date: Available online 23 September 2019Source: BrachytherapyAuthor(s): Christopher L. Guy, Emma C. Fields, Bridget A. Quinn, Christine M. Fisher, Colton J. Ladbury, Kara D. Romano, Dorin TodorAbstractPurposeThe purpose of the study was to investigate the impact on dose distribution and radiobiological metrics of common high-dose-rate vaginal brachytherapy treatment parameters and to analyze multiinstitutional data for clinically significant impact on outcomes in early-stage endometrial...
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Related ArticlesPost-gel shrinkage, elastic modulus, and stress generated by orthodontic adhesives. Angle Orthod. 2019 Sep 23;: Authors: Rasmussen MJ, Togrye C, Trojan TM, Tantbirojn D, Versluis A Abstract OBJECTIVES: To measure post-gel shrinkage, elastic modulus, and flexural strength of orthodontic adhesives and to predict shrinkage stress using finite element analysis (FEA). MATERIALS AND METHODS: The following 6 orthodontic adhesives were...
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Abstract Many organisms exhibit phenotypic plasticity; producing alternate phenotypes depending on the environment. Individuals can be plastic (intragenerational or direct plasticity) wherein individuals of the same genotype produce different phenotypes in response to the environments they experience. Alternatively, an individual’s phenotype may be under the control of its parents, usually the mother (transgenerational or indirect plasticity), so that mother’s genotype determines the phenotype produced...
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Related ArticlesErdafitinib for the treatment of urothelial cancer. Expert Rev Anticancer Ther. 2019 Sep 23;: Authors: Marandino L, Raggi D, Giannatempo P, Farè E, Necchi A Abstract Introduction: Fibroblast growth-factor receptor (FGFR) inhibition is a promising strategy of treatment in urothelial cancer (UC). FGFR3 mutations or fusions (mut/fus) are common in luminal-1 UC subtype, which exhibits poor responses to immunotherapy. Erdafitinib is a potent...
Related ArticlesThe use of intraperitoneal chemotherapy for gastric malignancies. Expert Rev Anticancer Ther. 2019 Sep 21;: Authors: Macrì A, Morabito F Abstract Introduction: Gastric cancer is the fourth/fifth most common malignancy and the second/third leading cause of cancer-related deaths worldwide, with only a quarter of patients achieving a 5-year survival rate. The treatment of gastric cancer, especially if advanced, often has poor results. It...
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Abstract Depression and anxiety risk are highly influenced by both genetic and environmental factors. Recently, it has been proposed that epigenetic mechanisms may also contribute to the transmission of both depression‐ and anxiety‐related behaviors across multiple generations. This review highlights long‐lasting epigenetic alterations observed in offspring of fathers, including some distinct effects on male and female offspring, in animal models. Available evidence emphasizes how both the developmental...
Abstract The striatum is mainly composed by medium spiny neurons (95 %) (MSNs). Although outnumbered, in other brain regions such as the hippocampus and the cortex, somatostatin interneurons (SSTi) are known to control and fine‐tune the activity of principal cells. This information is still fragmented for the striatum. Here, we questioned the striatal functional consequences of the selective ablation of SSTi in the striatum at the behavioral and cellular levels. We identified an increased excitability...
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Publication date: Available online 23 September 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Steve N. Georas
Publication date: Available online 23 September 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Marissa Hauptman, Jonathan M. Gaffin, Carter R. Petty, William.J. Sheehan, Peggy S. Lai, Brent Coull, Diane R. Gold, Wanda PhipatanakulAbstractObjectiveTo use spatial analysis methodology to analyze residential and school proximity to major roadways and pediatric asthma morbidity.MethodsThe School Inner-City Asthma Study (n=350) recruited school-aged children with asthma. Each participant’s...
Publication date: Available online 23 September 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): William W. Busse
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Publication date: Available online 23 September 2019Source: Journal of VoiceAuthor(s): Necati Enver, Can Doruk, Erdogan Kara, Kamber Kaşali, Hızır Asliyuksek, Bora BasaranSummaryObjectiveLaryngeal framework surgery has been a topic of interest since last decades. To succeed with least morbidity, the most important step is mastering the anatomy of larynx. In this study, we aim to show the relation between body height and laryngeal morphometrics that are important during laryngeal framework surgeries.Data...
Publication date: Available online 23 September 2019Source: Journal of VoiceAuthor(s): Jérôme R. Lechien, Kathy Huet, Camille Finck, Serge Blecic, Véronique Delvaux, Myriam Piccaluga, Sven Saussez, Bernard HarmegniesSummaryObjectiveAcoustic parameters are widely used as voice quality therapeutic outcomes in many laryngological diseases. The aim of this study is to explore the impact of changes in the nature and duration of the analyzed time interval and the vowel choice on the significance of the...
Publication date: Available online 23 September 2019Source: Journal of VoiceAuthor(s): Karen M. Crow, Miriam van Mersbergen, Alexis E. PayneSummaryVoices are, by nature, idiosyncratic representations of individuals because they possess anatomical, physiological, and psychological characteristics that are unique to them, which contribute to vocal output, and thus, establish the voice as a salient marker of their individuality. The areas of experimental psychology and cognitive neuroscience have examined...
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Related ArticlesPlasma Cell Mucositis of the Hard Palate. Ear Nose Throat J. 2019 Sep 23;:145561319872732 Authors: Micucci SB, Zim SA, Hosfield EM PMID: 31544489 [PubMed - as supplied by publisher]
Related ArticlesComparison of Temporalis Fascia and Transcanal Composite Chondroperichondrial Tympanoplasty Techniques. Ear Nose Throat J. 2019 Sep 23;:145561319875663 Authors: Gozeler MS, Sahin A Abstract The purpose of this study was to compare the success rates and hearing outcomes of transcanal composite chondroperichondrial cartilage graft with that of underlay temporal muscle fascia (TMF) graft for myringoplasty. In this retrospective study, the...
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Publication date: November 2019Source: Journal of Phonetics, Volume 77Author(s): Suyeon Yun, Yoonjung KangAbstractThis study examines the phonetic variation of the word-initial liquid in two dialects of Korean, Northern Hamkyeong Korean of North Korea and Seoul Korean of South Korea. The goals of the study are two-fold: to provide a thorough description of the phonetic variation in the word-initial liquid in these two dialects and to examine the acquisition of Seoul Korean features by North Koreans...
Publication date: November 2019Source: Journal of Phonetics, Volume 77Author(s): Antje SchweitzerAbstractThis article explores an exemplar-theoretic approach to the integration of phonetics and phonology in the prosodic domain. In an exemplar-theoretic perspective, prominence categories, here specifically, pitch-accented syllables and unaccented syllables, are assumed to correspond to accumulations of similar exemplars in an appropriate perceptual space. It should then be possible, as suggested for...
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Publication date: Available online 23 September 2019Source: World NeurosurgeryAuthor(s): Min Huang, Hongrong Qian, Junsen Wang, Qiyu Zhao, Tian’an JiangAbstractSchwannoma is a tumor arising from peripheral nerve sheaths and commonly occur in the head、neck and upper and lower extremities. Schwannoma in the presacral space is relatively rare and is often misdiagnosed before pathological diagnosis is made. Here we discussed a case of giant presacral schwannoma in a 34-year-old man with emphasis on imaging...
Publication date: Available online 23 September 2019Source: World NeurosurgeryAuthor(s): Rajesh Kumar Meena, Ramesh S. Doddamani, Hitesh K. Gurjar, Amandeep Jagdevan, Sarat P. ChandraAbstractBackgroundSplit cord malformations (SCMs) are among the rare congenital spinal anomalies. In 1992, Pang et al, proposed the “Unified theory of embryogenesis” and explained the formation of SCM type 1 and 2. This theory has been widely accepted in the neurosurgical literature, backed by several studies. However,...
Complete Transection of Optic Nerve After Endovascular Coiling of a Large Ophthalmic Artery Aneurysm
Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Barbara Verbraeken, Salah-Eddine Achahbar, Niels Kamerling, Laetitia Yperzeele, Maurits Voormolen, Tony Van Havenbergh, Tomas MenovskyBackgroundWe describe a patient who developed delayed blindness of the left eye at 5 weeks after endovascular coiling of a large ophthalmic aneurysm.Case DescriptionA 44-year-old male was admitted with visual decline due to compression of the optic nerve by a large ophthalmic aneurysm....
Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Naoto Kuroda, Chikanori Inenaga, Yoshifumi Arai, Yoshiro Otsuki, Tokutaro TanakaBackgroundImmunoglobulin (Ig)G4-related disease (IgG4-RD) was defined only recently and can be found in many organs. As intracranial lesions, hypophysitis and pachymeningitis are well known, whereas intracranial pseudotumor is unusual. This case involved multiple intracranial pseudotumors without extracranial lesions, mimicking multiple meningioma.Case...
Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Ralph J. Mobbs, Wen Jie Choy, Telvinderjit Singh, Lachlan Cassar, Chris Davidoff, Leigh Harris, Kevin Phan, Meinrad FiechterBackgroundIncomplete ossification of the pars interarticularis will result in a pars defect, a common cause of low back pain in youth and strongly associated with participation in high-impact sports. If left untreated, it can result in spondylolisthesis, causing dynamic canal stenosis, low back pain,...
Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Laura Pradini-Santos, Claudia L. Craven, Parag P. SayalEhlers-Danlos syndrome can be associated with cerebrospinal fluid (CSF) disturbances including recurrent CSF leak and Chiari I malformations. Persistent pseudomeningoceles are known to be associated with raised intracranial pressure. We present an unusual case of a compressive epidural CSF collection occurring after a computed tomography−guided L5 nerve root block...
Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Naohisa Miyakoshi, Michio Hongo, Yuji Kasukawa, Yoshinori Ishikawa, Daisuke Kudo, Yoichi ShimadaBackgroundSymptomatic calcification of the ligamentum flavum (CLF) is common in the cervical spine but rare in the thoracic spine. Rapidly progressing CLF in the thoracic spine has not been reported in the literature.Case DescriptionA 76-year-old Asian male experienced back pain after a fall and was diagnosed with osteoporotic...
Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Chirag A. BerryBackgroundOblique lumbar interbody fusion takes advantage of the wide interval between the aorta and left-sided psoas muscle to access the lumbar spine, allowing a minimally invasive approach for interbody fusion with lower associated morbidity. As this approach is gaining popularity among spine surgeons, it is important to understand the potential pitfalls that may arise in patients with congenital anomalies...
Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Hiroshi Uda, Takehiro Uda, Kosuke Nakajo, Yuta Tanoue, Takahiro Okuno, Saya Koh, Yohei Onishi, Hiroki Ohata, Yusuke Watanabe, Ryoko Umaba, Toshiyuki Kawashima, Kenji OhataBackgroundMixed germ cell tumors (MGCTs) usually occur in children. In the present report, we discuss an extremely rare case of adult-onset MGCT composed mainly of yolk sac tumor (YST) around the pineal gland.Case DescriptionA 54-year-old Japanese man...
Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Roberto Rodriguez Rubio, Ricky Chae, Ashna Khare, Todd Dubnicoff, Ethan Winkler, Emily Sloan, Andrew W. Bollen, Mitchel S. Berger, Adib A. AblaRadiation-induced telangiectasia of the central nervous system has been described predominantly in children, with up to 20% of patients affected after 3–41 years of radiotherapy.1, 2 We present the case of a 45-year-old male with a pontine pilocytic astrocytoma treated with standard-dose...
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Publication date: Available online 23 September 2019Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Wei Zhuang, Shuo Fang, Hao Fan, Weiye Zhu, Yong Chen, Weiya Tang, Chengling Liu, Liu Xingchen, Zhen Zhang, Xin Xing, Chao YangAbstractAimTo clarify the gross anatomy structure of the check ligament of the palpebra superior in relation to congenital blepharoptosis operation.MethodSeven fixed and three fresh cadavers of Chinese adults (between 53 and 76 years old; 5 males...
Publication date: Available online 24 September 2019Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Tru Dang, Nicholas Yim, Sailesh Tummala, Alan A. Parsa, Fereydoun Don ParsaSUMMARYThe use of povidone-iodine alone has been advocated by several authors who continued to utilize it for pocket irrigation despite the US Food and Drug Administration (FDA)’s prohibition of 2000. However, in 2017, the FDA removed the ban against povidone-iodine use in breast augmentation.In...
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117 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
117 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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3376 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/09/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
3376 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/09/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Key points •Employing quantitative Na+‐imaging and FRET‐based imaging with ATeam1.03YEMK (ATeam), we studied the relation between activity‐induced Na+ influx and intracellular ATP in CA1 pyramidal neurons of the mouse hippocampus. •Calibration of ATeam in situ enabled a quantitative estimate of changes in intracellular ATP concentrations. •Different paradigms of stimulation that induced global Na+ influx into the entire neuron resulted in decreases in [ATP] in the range of 0.1‐0.6 mM in somata...
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