Antibiotics, Vol. 8, Pages 155: Characterization of LysBC17, a Lytic Endopeptidase from Bacillus cereus Antibiotics doi: 10.3390/antibiotics8030155 Authors: Swift Etobayeva Reid Waters Oakley Donovan Nelson Bacillus cereus, a Gram-positive bacterium, is an agent of food poisoning. B. cereus is closely related to Bacillus anthracis, a deadly pathogen for humans, and Bacillus thuringenesis, an insect pathogen. Due to the growing prevalence of antibiotic resistance...
Thu Sep 19, 2019 03:00
Antibiotics, Vol. 8, Pages 154: Antibiotic Use: A Cross-Sectional Study Evaluating the Understanding, Usage and Perspectives of Medical Students and Pathfinders of a Public Defence University in Malaysia Antibiotics doi: 10.3390/antibiotics8030154 Authors: Mainul Haque Nor Azlina A. Rahman Judy McKimm Massimo Sartelli Golam Mohammad Kibria Md Zakirul Islam Siti Nur Najihah Binti Lutfi Nur Syamirah Aishah Binti Othman Shahidah Leong Binti Abdullah Background: Antimicrobial...
Thu Sep 19, 2019 03:00
Antioxidants, Vol. 8, Pages 418: Salivary Antioxidants Status Following Progressive Aerobic Exercise: What Are the Differences between Waterpipe Smokers and Non-Smokers? Antioxidants doi: 10.3390/antiox8100418 Authors: Arazi Taati Rafati Sajedi Suzuki Waterpipe tobacco (WPT) smoking is a public health problem with similar or even stronger effects than cigarette smoking. Although it appears to be associated with extensive oxidative stress, there is a limited number of studies...
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Antioxidants, Vol. 8, Pages 417: Biological and Chemical Insights of Beech (Fagus sylvatica L.) Bark: A Source of Bioactive Compounds with Functional Properties Antioxidants doi: 10.3390/antiox8090417 Authors: Tanase Mocan Coșarcă Gavan Nicolescu Gheldiu Vodnar Muntean Crișan The present study aimed, on the one hand, to improve the yield of microwave assisted extraction (MAE) of polyphenols from beech bark by using a design of experiments (DoE) approach....
Thu Sep 19, 2019 03:00
Antioxidants, Vol. 8, Pages 416: Antioxidant and Anti-Inflammatory Properties of a Thuja occidentalis Mother Tincture for the Treatment of Ulcerative Colitis Antioxidants doi: 10.3390/antiox8090416 Authors: Miruna Silvia Stan Sorina Nicoleta Voicu Sonia Caruntu Ionela Cristina Nica Neli-Kinga Olah Ramona Burtescu Cornel Balta Marcel Rosu Hildegard Herman Anca Hermenean Anca Dinischiotu Inflammatory bowel disease (IBD) represents a group of chronic autoimmune...
Thu Sep 19, 2019 03:00
Antioxidants, Vol. 8, Pages 415: Chemical Profiling of Polyphenolics in Eucalyptus globulus and Evaluation of Its Hepato–Renal Protective Potential Against Cyclophosphamide Induced Toxicity in Mice Antioxidants doi: 10.3390/antiox8090415 Authors: Mosad A. Ghareeb Mansour Sobeh Walaa H. El-Maadawy Hala Sh. Mohammed Heba Khalil Sanaa Botros Michael Wink Cyclophosphamide (CP) is a potent anti-neoplastic and immunosuppressive agent; however, it causes multi-organ toxicity....
Thu Sep 19, 2019 03:00
Arts, Vol. 8, Pages 122: The Dynamic Display of Art Holography Arts doi: 10.3390/arts8030122 Authors: M. Melissa Crenshaw Holograms have been displayed in single-artist and group exhibitions, since the late 1960’s. The content within a holographic image can be greatly compromised if the hologram is not displayed correctly. Holography exhibitions can either enhance or diminish the impact of the images depending on how the exhibit layout and lighting are designed. This paper...
Thu Sep 19, 2019 03:00
Atmosphere, Vol. 10, Pages 564: A Wind Tunnel Study on the Correlation between Urban Space Quantification and Pedestrian–Level Ventilation Atmosphere doi: 10.3390/atmos10100564 Authors: Li Peng Ji Hu Ding Correlation research on urban space and pedestrian–level wind (PLW) environments is helpful for improving the wind comfort in complex urban space. It could also be significant for building and urban design. Correlation research is usually carried out in a...
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Atmosphere, Vol. 10, Pages 563: Contribution of Meteorological Conditions to the Variation in Winter PM2.5 Concentrations from 2013 to 2019 in Middle-Eastern China Atmosphere doi: 10.3390/atmos10100563 Authors: Liu Wang Shen Peng Shi Che Wang Severe air pollution events accompanied by high PM2.5 concentrations have been repeatedly observed in Middle-Eastern China since 2013 and decreased in recent years. The reason for this caused widespread attention. The month...
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Atmosphere, Vol. 10, Pages 562: On Evolution of Young Wind Waves in Time and Space Atmosphere doi: 10.3390/atmos10090562 Authors: Shemer The mechanisms governing the evolution of the wind-wave field in time and in space are not yet fully understood. Various theoretical approaches have been offered to model wind-wave generation. To examine their validity, detailed and accurate experiments under controlled conditions have to be carried out. Since it is next to impossible to get the required...
Thu Sep 19, 2019 03:00
Behavioral Sciences, Vol. 9, Pages 102: The Effect of Different Rejection Letters on Applicants’ Reactions Behavioral Sciences doi: 10.3390/bs9100102 Authors: Cortini Galanti Barattucci Organisations appear to pay little attention to rejection letters, considered a special form of organisational communication, despite a growing body of literature that shows they play an important role in terms of employer branding. This study aims to empirically test how applicants’...
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Bioengineering, Vol. 6, Pages 87: An “In-Situ Binding” Approach to Produce Torrefied Biomass Briquettes Bioengineering doi: 10.3390/bioengineering6040087 Authors: Bu Aamiri Thilakaratne Tumuluru Satyavolu Biomass-derived coal or “biocoal” produced using a torrefaction process presents a carbon-neutral option of coal for power generation. While torrefaction delivers a carbon content and hydrophobicity comparable to coal, it lowers its density and creates...
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Bioengineering, Vol. 6, Pages 86: Assessment of the Inner Surface Microstructure of Decellularized Cortical Bone by a Scanning Electron Microscope Bioengineering doi: 10.3390/bioengineering6030086 Authors: Jeong Asai Ushida Furukawa The microstructural changes of bones, which form a hierarchy of skeletal tissue, vary, depending on their condition, and are affected by the behaviors of bone cells. The purpose of this study is to assess the microstructural changes in the inner...
Thu Sep 19, 2019 03:00
Bioengineering, Vol. 6, Pages 85: In-Line Monitoring of Polyhydroxyalkanoate (PHA) Production during High-Cell-Density Plant Oil Cultivations Using Photon Density Wave Spectroscopy Bioengineering doi: 10.3390/bioengineering6030085 Authors: Björn Gutschmann Thomas Schiewe Manon T.H. Weiske Peter Neubauer Roland Hass Sebastian L. Riedel Polyhydroxyalkanoates (PHAs) are biodegradable plastic-like materials with versatile properties. Plant oils are excellent carbon sources...
Thu Sep 19, 2019 03:00
Biomolecules, Vol. 9, Pages 510: Sustained Neurotrophin Release from Protein Nanoparticles Mediated by Matrix Metalloproteinases Induces the Alignment and Differentiation of Nerve Cells Biomolecules doi: 10.3390/biom9100510 Authors: Matsuzaki Maruta Takaki Kotani Kato Yoshimura Endo Whitty Pernstich Gandhi Jones Mori The spatial and temporal availability of cytokines, and the microenvironments this creates, is critical to tissue development...
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Biomolecules, Vol. 9, Pages 509: Pharmacokinetic Properties of Fluorescently Labelled Hydroxypropyl-Beta-Cyclodextrin Biomolecules doi: 10.3390/biom9100509 Authors: Váradi Hermenean Gesztelyi Jeney Balogh Majoros Malanga Fenyvesi Szente Bácskay Vecsernyés Fehér Ujhelyi Vasvári Árvai Rusznyák Balta Herman Fenyvesi 2-Hydroxypropyl-beta-cyclodextrin (HPBCD) is utilized in the formulation of pharmaceutical products...
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Biomolecules, Vol. 9, Pages 508: Mutational Analysis of a Highly Conserved PLSSMXP Sequence in the Small Subunit of Bacillus licheniformis γ-Glutamyltranspeptidase Biomolecules doi: 10.3390/biom9090508 Authors: Meng-Chun Chi Huei-Fen Lo Min-Guan Lin Yi-Yu Chen Tzu-Fan Wang Long-Liu Lin A highly conserved 458PLSSMXP464 sequence in the small subunit (S-subunit) of an industrially important Bacillus licheniformis γ-glutamyltranspeptidase (BlGGT) was identified by...
Thu Sep 19, 2019 03:00
Biomolecules, Vol. 9, Pages 507: Proteolytic Activity in Meadow Soil after the Application of Phytohormones Biomolecules doi: 10.3390/biom9090507 Authors: Holik Vranová Phytohormones, similar to soil enzymes, are synthesized and secreted into the soil environment by fungi and microorganisms. Phytohormones are involved in regulating microbial community activity in the rhizosphere. This paper examines how auxins, cytokinins, ethephon and chlorocholine chloride affect the activity...
Thu Sep 19, 2019 03:00
Biomolecules, Vol. 9, Pages 506: Mechanical Deformation and Electronic Structure of a Blue Copper Azurin in a Solid-State Junction Biomolecules doi: 10.3390/biom9090506 Authors: Carlos Romero-Muñiz María Ortega J. G. Vilhena Ismael Diéz-Pérez Juan Carlos Cuevas Rubén Pérez Linda A. Zotti Protein-based electronics is an emerging field which has attracted considerable attention over the past decade. Here, we present a theoretical study of the formation and electronic...
Thu Sep 19, 2019 03:00
Biomolecules, Vol. 9, Pages 505: Elevated SH3BP5 Correlates with Poor Outcome and Contributes to the Growth of Acute Myeloid Leukemia Cells Biomolecules doi: 10.3390/biom9090505 Authors: Minjing Li Shiyu Hao Chunling Li Huimin Xiao Liyuan Sun Zhenhai Yu Naili Zhang Yanlian Xiong Dongmei Zhao Yancun Yin Current strategies are not especially successful in the treatment of acute myeloid leukemia (AML). The identification and characterization of oncogenes crucial...
Thu Sep 19, 2019 03:00
Biosensors, Vol. 9, Pages 111: Flexible PET/ITO/Ag SERS Platform for Label-Free Detection of Pesticides Biosensors doi: 10.3390/bios9030111 Authors: Nowicka Czaplicka Kowalska Szymborski Kamińska We show a new type of elastic surface-enhanced Raman spectroscopy (SERS) platform made of poly(ethylene terephthalate) (PET) covered with a layer of indium tin oxide (ITO). This composite is subjected to dielectric barrier discharge (DBD) that develops the active surface of...
Thu Sep 19, 2019 03:00
Biosensors, Vol. 9, Pages 110: Latest Trends in Biosensing for Microphysiological Organs-on-a-Chip and Body-on-a-Chip Systems Biosensors doi: 10.3390/bios9030110 Authors: Kratz Höll Schuller Ertl Rothbauer Organs-on-chips are considered next generation in vitro tools capable of recreating in vivo like, physiological-relevant microenvironments needed to cultivate 3D tissue-engineered constructs (e.g., hydrogel-based organoids and spheroids) as well as tissue barriers....
Thu Sep 19, 2019 03:00
Brain Sciences, Vol. 9, Pages 242: Using an Overlapping Time Interval Strategy to Study Diagnostic Instability in Mild Cognitive Impairment Subtypes Brain Sciences doi: 10.3390/brainsci9090242 Authors: David Facal Joan Guàrdia-Olmos Arturo X. Pereiro Cristina Lojo-Seoane Maribel Peró Onésimo Juncos-Rabadán (1) Background: Mild cognitive impairment (MCI) is a diagnostic label in which stability is typically low. The aim of this study was to examine temporal changes in the...
Thu Sep 19, 2019 03:00
Brain Sciences, Vol. 9, Pages 241: Fumaric Acids Do Not Directly Influence Gene Expression of Neuroprotective Factors in Highly Purified Rodent Astrocytes Brain Sciences doi: 10.3390/brainsci9090241 Authors: Kaweh Pars Marina Gingele Jessica Kronenberg Chittappen K Prajeeth Thomas Skripuletz Refik Pul Roland Jacobs Viktoria Gudi Martin Stangel (1) Background: Dimethylfumarate (DMF) has been approved for the treatment of relapsing remitting multiple sclerosis....
Thu Sep 19, 2019 03:00
Brain Sciences, Vol. 9, Pages 240: Genetic Predisposition and Disease Expression of Bipolar Disorder Reflected in Shape Changes of the Anterior Limbic Network Brain Sciences doi: 10.3390/brainsci9090240 Authors: Chia-Feng Lu Yu-Te Wu Shin Teng Po-Shan Wang Pei-Chi Tu Tung-Ping Su Chi-Wen Jao Cheng-Ta Li Bipolar disorder (BD) is a genetically and phenotypically complex psychiatric disease. Although previous studies have suggested that the relatives of BD patients...
Thu Sep 19, 2019 03:00
Cancers, Vol. 11, Pages 1403: Hypoxia Downregulates LPP3 and Promotes the Spatial Segregation of ATX and LPP1 During Cancer Cell Invasion Cancers doi: 10.3390/cancers11091403 Authors: Harper Brochu-Gaudreau Saucier Dubois Hypoxia is a common characteristic of advanced solid tumors and a potent driver of tumor invasion and metastasis. Recent evidence suggests the involvement of autotaxin (ATX) and lysophosphatidic acid receptors (LPARs) in cancer cell invasion promoted by...
Thu Sep 19, 2019 03:00
Cancers, Vol. 11, Pages 1402: Hyperglycemia Associated Metabolic and Molecular Alterations in Cancer Risk, Progression, Treatment, and Mortality Cancers doi: 10.3390/cancers11091402 Authors: Ramteke Deb Shepal Bhat Cancer and diabetes are amongst the leading causes of deaths worldwide. There is an alarming rise in cancer incidences and mortality, with approximately 18.1 million new cases and 9.6 million deaths in 2018. A major contributory but neglected factor for risk of...
Thu Sep 19, 2019 03:00
Cancers, Vol. 11, Pages 1399: Matched Whole-Genome Sequencing (WGS) and Whole-Exome Sequencing (WES) of Tumor Tissue with Circulating Tumor DNA (ctDNA) Analysis: Complementary Modalities in Clinical Practice Cancers doi: 10.3390/cancers11091399 Authors: Robin Imperial Marjan Nazer Zaheer Ahmed Audrey E. Kam Timothy J. Pluard Waled Bahaj Mia Levy Timothy M. Kuzel Dana M. Hayden Sam G. Pappas Janakiraman Subramanian Ashiq Masood Tumor heterogeneity, especially...
Thu Sep 19, 2019 03:00
Cancers, Vol. 11, Pages 1400: Blockade of PD-L1 Enhances Cancer Immunotherapy by Regulating Dendritic Cell Maturation and Macrophage Polarization Cancers doi: 10.3390/cancers11091400 Authors: Nai-Yun Sun Yu-Li Chen Wen-Yih Wu Han-Wei Lin Ying-Cheng Chiang Chi-Fang Chang Yi-Jou Tai Heng-Cheng Hsu Chi-An Chen Wei-Zen Sun Wen-Fang Cheng The immuno-inhibitory checkpoint PD-L1, regulated by tumor cells and antigen-presenting cells (APCs), dampened the activation...
Thu Sep 19, 2019 03:00
Cancers, Vol. 11, Pages 1401: Prognostic and Predictive Implications of PTEN in Breast Cancer: Unfulfilled Promises but Intriguing Perspectives Cancers doi: 10.3390/cancers11091401 Authors: Luisa Carbognin Federica Miglietta Ida Paris Maria Vittoria Dieci The characterization of tumor biology and consequently the identification of prognostic and predictive biomarkers represent key issues for the translational research in breast cancer (BC). Phosphatase and tensin homolog deleted...
Thu Sep 19, 2019 03:00
Cancers, Vol. 11, Pages 1397: γ-H2AX Foci Persistence at Chromosome Break Suggests Slow and Faithful Repair Phases Restoring Chromosome Integrity Cancers doi: 10.3390/cancers11091397 Authors: Michelle Ricoul Tamizh Selvan Gnana Sekaran Patricia Brochard Cecile Herate Laure Sabatier Many toxic agents can cause DNA double strand breaks (DSBs), which are in most cases quickly repaired by the cellular machinery. Using ionising radiation, we explored the kinetics of DNA lesion...
Thu Sep 19, 2019 03:00
Cancers, Vol. 11, Pages 1396: Dendritic Cell-Based and Other Vaccination Strategies for Pediatric Cancer Cancers doi: 10.3390/cancers11091396 Authors: Sévérine de Bruijn Sébastien Anguille Joris Verlooy Evelien L. Smits Viggo F. van Tendeloo Maxime de Laere Koenraad Norga Zwi N. Berneman Eva Lion Dendritic cell-based and other vaccination strategies that use the patient’s own immune system for the treatment of cancer are gaining momentum. Most studies...
Thu Sep 19, 2019 03:00
Cancers, Vol. 11, Pages 1398: CD8+ and Regulatory T cells Differentiate Tumor Immune Phenotypes and Predict Survival in Locally Advanced Head and Neck Cancer Cancers doi: 10.3390/cancers11091398 Authors: Alessia Echarti Markus Hecht Maike Büttner-Herold Marlen Haderlein Arndt Hartmann Rainer Fietkau Luitpold Distel Background: The tumor immune status “inflamed”, “immune excluded”, and “desert” might serve as...
Thu Sep 19, 2019 03:00
Cells, Vol. 8, Pages 1111: Proteomic Analysis of miR-195 and miR-497 Replacement Reveals Potential Candidates that Increase Sensitivity to Oxaliplatin in MSI/P53wt Colorectal Cancer Cells Cells doi: 10.3390/cells8091111 Authors: Poel Boyd Beekhof Schelfhorst Pham Piersma Knol Jimenez Verheul Buffart Most patients with advanced colorectal cancer (CRC) eventually develop resistance to systemic combination therapy. miR-195-5p and miR-497-5p are downregulated...
Thu Sep 19, 2019 03:00
Cells, Vol. 8, Pages 1109: Dynamic Interplay between Pericytes and Endothelial Cells during Sprouting Angiogenesis Cells doi: 10.3390/cells8091109 Authors: Giulia Chiaverina Laura di Blasio Valentina Monica Massimo Accardo Miriam Palmiero Barbara Peracino Marianela Vara-Messler Alberto Puliafito Luca Primo Vascular physiology relies on the concerted dynamics of several cell types, including pericytes, endothelial, and vascular smooth muscle cells. The interactions...
Thu Sep 19, 2019 03:00
Cells, Vol. 8, Pages 1110: FOXO3a from the Nucleus to the Mitochondria: A Round Trip in Cellular Stress Response Cells doi: 10.3390/cells8091110 Authors: Fasano Disciglio Bertora Simone : Cellular stress response is a universal mechanism that ensures the survival or negative selection of cells in challenging conditions. The transcription factor Forkhead box protein O3 (FOXO3a) is a core regulator of cellular homeostasis, stress response, and longevity since it can modulate...
Thu Sep 19, 2019 03:00
Cells, Vol. 8, Pages 1108: Environmentally-Induced Transgenerational Epigenetic Inheritance: Implication of PIWI Interacting RNAs Cells doi: 10.3390/cells8091108 Authors: Karine Casier Antoine Boivin Clément Carré Laure Teysset Environmentally-induced transgenerational epigenetic inheritance is an emerging field. The understanding of associated epigenetic mechanisms is currently in progress with open questions still remaining. In this review, we present an overview of the knowledge...
Thu Sep 19, 2019 03:00
Cells, Vol. 8, Pages 1107: Functions and Regulatory Mechanisms of lncRNAs in Skeletal Myogenesis, Muscle Disease and Meat Production Cells doi: 10.3390/cells8091107 Authors: Shanshan Wang Jianjun Jin Zaiyan Xu Bo Zuo Myogenesis is a complex biological process, and understanding the regulatory network of skeletal myogenesis will contribute to the treatment of human muscle related diseases and improvement of agricultural animal meat production. Long noncoding RNAs (lncRNAs) serve...
Thu Sep 19, 2019 03:00
Cells, Vol. 8, Pages 1106: Regulation of Ketogenic Enzyme HMGCS2 by Wnt/β-catenin/PPARγ Pathway in Intestinal Cells Cells doi: 10.3390/cells8091106 Authors: Ji Tae Kim Chang Li Heidi L. Weiss Yuning Zhou Chunming Liu Qingding Wang B. Mark Evers The Wnt/β-catenin pathway plays a crucial role in development and renewal of the intestinal epithelium. Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase 2 (HMGCS2), a rate-limiting ketogenic enzyme in the synthesis...
Thu Sep 19, 2019 03:00
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