Abstract The striatum is mainly composed by medium spiny neurons (95 %) (MSNs). Although outnumbered, in other brain regions such as the hippocampus and the cortex, somatostatin interneurons (SSTi) are known to control and fine‐tune the activity of principal cells. This information is still fragmented for the striatum. Here, we questioned the striatal functional consequences of the selective ablation of SSTi in the striatum at the behavioral and cellular levels. We identified an increased excitability...
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Abstract Depression and anxiety risk are highly influenced by both genetic and environmental factors. Recently, it has been proposed that epigenetic mechanisms may also contribute to the transmission of both depression‐ and anxiety‐related behaviors across multiple generations. This review highlights long‐lasting epigenetic alterations observed in offspring of fathers, including some distinct effects on male and female offspring, in animal models. Available evidence emphasizes how both the developmental...
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Related ArticlesThe use of intraperitoneal chemotherapy for gastric malignancies. Expert Rev Anticancer Ther. 2019 Sep 21;: Authors: Macrì A, Morabito F Abstract Introduction: Gastric cancer is the fourth/fifth most common malignancy and the second/third leading cause of cancer-related deaths worldwide, with only a quarter of patients achieving a 5-year survival rate. The treatment of gastric cancer, especially if advanced, often has poor results. It...
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Related ArticlesErdafitinib for the treatment of urothelial cancer. Expert Rev Anticancer Ther. 2019 Sep 23;: Authors: Marandino L, Raggi D, Giannatempo P, Farè E, Necchi A Abstract Introduction: Fibroblast growth-factor receptor (FGFR) inhibition is a promising strategy of treatment in urothelial cancer (UC). FGFR3 mutations or fusions (mut/fus) are common in luminal-1 UC subtype, which exhibits poor responses to immunotherapy. Erdafitinib is a potent...
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Publication date: 8 October 2019Source: Vaccine, Volume 37, Issue 43Author(s):
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Publication date: Available online 23 September 2019Source: VaccineAuthor(s): Mehrnaz Mostafapour, Samantha B Meyer, Abigail ScholerAbstractIn the era in which people are bombarded with misinformation about vaccination, research regarding the degree to which various types of risk or benefit information affect perceptions of vaccines and intentions to vaccinate is critical. The present research utilizes a robust methodology to quantify the extent to which risk and benefit information affects vaccination...
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Publication date: Available online 23 September 2019Source: VaccineAuthor(s): Mohammad HajizadehAbstractExtant work suggested pro-rich distribution of vaccination coverage in low- and middle-income countries (LMICs). However, the current literature also suggested pro-poor distribution of vaccination in some countries, including the Gambia, the Kyrgyz Republic and Namibia. This study aimed to explain socioeconomic inequalities in the completion rate of the four-core vaccines (i.e., Bacille Calmette-Guérin...
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Publication date: Available online 23 September 2019Source: VaccineAuthor(s): Jody Tate, Teresa Aguado, Jan De Belie, Daphne Holt, Emilie Karafillakis, Heidi J. Larson, Sam Nye, David Salisbury, Mariano Votta, Suzanne WaitAbstractVaccination beyond childhood brings significant benefits at the individual, community and socio-economic levels. Despite this, immunisation programmes often fail to deliver the vaccines which could protect those at risk of vaccine-preventable diseases. In this commentary,...
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Publication date: September 2019Source: Journal of Dermatological Science, Volume 95, Issue 3Author(s):
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Publication date: September 2019Source: Journal of Dermatological Science, Volume 95, Issue 3Author(s):
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Abstract Penalized regression splines and distributed lag models were used to evaluate the effects of species mixing on productivity and climate-related resistance via tree-ring width measurements from sample cores. Data were collected in Lower Austria from sample plots arranged in a triplet design. Triplets were established for sessile oak [Quercus petraea (Matt.) Liebl.] and Scots pine (Pinus sylvestris L.), European beech (Fagus sylvatica L.) and Norway spruce [Picea abies (L.)...
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Publication date: December 2019Source: Accident Analysis & Prevention, Volume 133Author(s): Naikan Ding, Nisha Jiao, Shunying Zhu, Bing LiuAbstractIn this study, we attempted to explain drivers’ crash risk variation in car-following for crash avoidance considering the effects of drivers’ visual perception, vehicle type, and horizontal curves, with a structural equations model. The model was built by incorporating drivers’ speed risk perception and distance risk perception as latent variables....
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Related ArticlesPost-gel shrinkage, elastic modulus, and stress generated by orthodontic adhesives. Angle Orthod. 2019 Sep 23;: Authors: Rasmussen MJ, Togrye C, Trojan TM, Tantbirojn D, Versluis A Abstract OBJECTIVES: To measure post-gel shrinkage, elastic modulus, and flexural strength of orthodontic adhesives and to predict shrinkage stress using finite element analysis (FEA). MATERIALS AND METHODS: The following 6 orthodontic adhesives were...
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Related ArticlesEffect of systematic desensitization training on acceptable noise levels in adults with normal hearing sensitivity. Noise Health. 2018 May-Jun;20(94):83-89 Authors: Pitchaimuthu A, Arora A, Bhat JS, Kanagokar V Abstract Context: The willingness of a person to accept noise while listening to speech can be measured using the acceptable noise level (ANL) test. Individuals with poor ANL are unlikely to become successful hearing aid users....
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Publication date: Available online 23 September 2019Source: BrachytherapyAuthor(s): Christopher L. Guy, Emma C. Fields, Bridget A. Quinn, Christine M. Fisher, Colton J. Ladbury, Kara D. Romano, Dorin TodorAbstractPurposeThe purpose of the study was to investigate the impact on dose distribution and radiobiological metrics of common high-dose-rate vaginal brachytherapy treatment parameters and to analyze multiinstitutional data for clinically significant impact on outcomes in early-stage endometrial...
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Publication date: Available online 24 September 2019Source: Behavioural Brain ResearchAuthor(s): Kennett D. Radford, Haley F. Spencer, Michael Zhang, Rina Y. Berman, Quinn L. Girasek, Kwang H. ChoiAbstractKetamine is a multimodal dissociative anesthetic and analgesic that is widely used after traumatic injury. We previously reported that an analgesic dose of intravenous (IV) ketamine infusion (10 mg/kg, 2-hr) after fear conditioning enhanced short-term fear memory in rats. Here, we investigated the...
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59 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/09/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Publication date: Available online 23 September 2019Source: Journal of EthnopharmacologyAuthor(s): Abbas Imani-Baran, Jalal Abdollahi, Hamid Akbari, Saeed Jafarirad, Sajjad MoharramnejadAbstractEthnopharmacological relevanceTrachyspermum ammi has been used traditionally as a popular ethnobotanical plant in human and animal parasitic infestations. Few scientific studies have been conducted on in vitro anthelmintic activity of T. ammi against various helminths and there is no study on its in vivo/in...
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Related ArticlesInvestigational Monoclonal Antibodies in the Treatment of Multiple Myeloma: A Systematic Review of Agents under Clinical Development. Antibodies (Basel). 2019 May 24;8(2): Authors: Iftikhar A, Hassan H, Iftikhar N, Mushtaq A, Sohail A, Rosko N, Chakraborty R, Razzaq F, Sandeep S, Valent JN, Kanate AS, Anwer F Abstract BACKGROUND: Immunotherapy for multiple myeloma (MM) has been the focus in recent years due to its myeloma-specific immune...
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Related ArticlesAn Open-Source Tool for Anisotropic Radiation Therapy Planning in Neuro-oncology Using DW-MRI Tractography. Front Oncol. 2019;9:810 Authors: Jordan K, Morin O, Wahl M, Amirbekian B, Chapman C, Owen J, Mukherjee P, Braunstein S, Henry R Abstract There is evidence from histopathological studies that glioma tumor cells migrate preferentially along large white matter bundles. If the peritumoral white matter structures can be used to predict...
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Related ArticlesEURACAN/IASLC proposals for updating the histologic classification of pleural mesothelioma: towards a more multidisciplinary approach. J Thorac Oncol. 2019 Sep 20;: Authors: Nicholson AG, Sauter JL, Nowak AK, Kindler HL, Gill RR, Remy-Jardin M, Armato SG, Fernandez-Cuesta L, Bueno R, Alcala N, Foll M, Pass H, Attanoos R, Baas P, Beasley MB, Brcic L, Butnor KJ, Chirieac LR, Churg A, Courtiol P, Dacic S, De Perrot M, Frauenfelder T, Gibbs A, Hirsch FR, Hiroshima...
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Related ArticlesMicroRNA‑381 regulates the growth of gastric cancer cell by targeting TWIST1. Mol Med Rep. 2019 Sep 06;: Authors: Yin Y, Li X, Guo Z, Zhou F Abstract Gastric cancer (GC) has one of the highest mortality rates among all types of cancer in the world. At present, an efficient treatment for GC remains elusive. Studies have demonstrated that microRNAs (miRs) are abnormally expressed in cancer, and that these serve important roles in the development...
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Related ArticlesIn silico study of pseudoprogression in glioblastoma: collaboration of radiologists and radiation oncologists in the estimation of extent of high dose RT region. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2019 Sep 13;: Authors: Belanova R, Sprlakova-Pukova A, Standara M, Janu E, Koukalova R, Kristek J, Burkon P, Kolouskova I, Prochazka T, Pospisil P, Chakravarti A, Slampa P, Slaby O, Kazda T Abstract BACKGROUND AND AIM: Oncologists...
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Related ArticlesPrevention of Gestational Diabetes Mellitus (GDM) and Probiotics: Mechanism of action: A Review. Curr Diabetes Rev. 2019 Jul 12;: Authors: Homayouni A, Bagheri N, Mohammad-Alizadeh-Charandabi S, Kashani N, Mobaraki-Asl N, Mirghafurvand M, Asgharian H, Ansari F, Pourjafar H Abstract BACKGROUND: Gestational Diabetes Mellitus (GDM) is a health problem that is increasing around the world. INTRODUCTION: Prevention of GDM, rather than...
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Related ArticlesTreatment patterns and overall survival among patients with unresectable, stage III non-small-cell lung cancer. Future Oncol. 2019 Sep 23;: Authors: Bobbili P, Ryan K, Duh MS, Dua A, Fernandes AW, Pavilack M, Gomez JE Abstract Aim: To analyze treatment patterns and overall survival (OS) across time (2009-2014) among patients with unresected, stage III non-small-cell lung cancer (NSCLC). Patients & methods: Stage III NSCLC patients...
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Related ArticlesImplications of Cystectomy Travel Distance for Hospital Readmission and Survival. Clin Genitourin Cancer. 2019 Aug 20;: Authors: Hale NE, Macleod LC, Yabes JG, Turner RM, Fam MM, Gingrich JR, Skolarus TA, Borza T, Sabik LM, Davies BJ, Jacobs BL Abstract BACKGROUND: Regionalization of complex surgical care results in increasing need for patients to travel for complex oncologic procedures such as cystectomy in bladder cancer. We examined...
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Related Articles[E-health and "Cancer outside the hospital walls", Big Data and artificial intelligence]. Bull Cancer. 2019 Sep 19;: Authors: Bertucci F, Le Corroller-Soriano AG, Monneur A, Fluzin S, Viens P, Maraninchi D, Goncalves A Abstract To heal otherwise in oncology has become an imperative of Public Health and an economic imperative in France. Patients can therefore receive live most of their care outside of hospital with more ambulatory care....
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Publication date: Available online 23 September 2019Source: Advanced Powder TechnologyAuthor(s): Shangyi Yin, Wenqi Zhong, Tao Song, Ping Lu, Yuhang ChenAbstractTo understand the behaviors of particle clusters in the circulating fluidized bed (CFB), experiments were conducted with glass beads to acquire the image sequences of gas-solid flow on a CFB riser with a 100 mm × 25 mm cross-section and 3.2 m in length by adopting high-speed photography. An image multilevel thresholding approach using k-means...
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Publication date: Available online 23 September 2019Source: Advanced Powder TechnologyAuthor(s): Ying Cui, Wenqi Zhong, Jun Xiang, Guoyao LiuAbstractUsing supercritical carbon dioxide (S-CO2) as the working fluid integrated in a circulating fluidized bed (CFB) boiler is a rising technology used to improve the power generation efficiency and reduce gas pollutant emissions in coal-fired power generation systems. This study established a comprehensive 3-D model based on an Eulerian-Lagrangian frame...
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Publication date: 1 February 2020Source: Talanta, Volume 208Author(s): Estefani P. Simão, Dammyres B.S. Silva, Marli T. Cordeiro, Laura H.V. Gil, Cesar A.S. Andrade, Maria D.L. OliveiraAbstractArboviruses have been emerging as a significant global health problem due to the recurrent epidemics. Arboviruses require the development of new diagnostic devices due to the nonspecific clinical manifestations. Herein, we report a biosensor based on cysteine (Cys), zinc oxide nanoparticles (ZnONp), and Concanavalin...
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Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): Fereshteh Shahhoseini, Ali Azizi, Stefana N. Egli, Christina S. BottaroAbstractThe need for high throughput, reliable analytical methods for environmental analysis has driven our development of novel sampling technologies that can be used in microextraction devices and integrated into chromatographic systems for fast analysis. Here we report a new method of water analysis for 16 EPA priority polycyclic aromatic hydrocarbons (PAHs)...
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Publication date: Available online 24 September 2019Source: TalantaAuthor(s): Chidkamon Thunkhamrak, Prakit Chuntib, Kontad Ounnunkad, Philippe Banet, Pierre-Henri Aubert, Gopalan Saianand, Anantha-Iyengar Gopalan, Jaroon JakmuneeAbstractIn this work, we developed an effective voltammetric immunosensing platform for the sensitive detection of prostate specific antigen (PSA) utilizing a graphene oxide (GO) modified screen-printed carbon electrode (SPCE) hybridized with the ex-situ prepared silver...
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Publication date: Available online 23 September 2019Source: TalantaAuthor(s): Chunxia Wang, Caiwen Pan, Xiaoran Wei, Fan Yang, Wenjie Wu, Lanqun MaoAbstractLiquid fuels rich in aliphatic and aromatic carbon compounds are utilized as the carbon precursors for the production of carbon dots (CDs) for the first time. Herein we demonstrate the preparation of liquid fuels derived CDs (d-CDs and f-CDs) via chemical oxidation approach and the subsequent application for cerebral copper ions (Cu2+) sensing...
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Publication date: Available online 23 September 2019Source: TalantaAuthor(s): David Perez-Guaita, Guillermo Quintas, Zeineb Farhane, Roma Tauler, Hugh J. ByrneAbstractRaman microspectroscopy is gaining popularity for the analysis of time-dependent biological processes such as drug uptake and cellular response. It is a label-free technique which acquires signals from a large variety of components, including cell biomolecules and exogenous compounds such as drugs and nanoparticles, and is commonly...
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Publication date: Available online 24 September 2019Source: Journal of Pediatric Surgery Case ReportsAuthor(s): Gabriel Pinheiro Martins de Almeida e Souza, Matheus Eugênio de Sousa Lima, Aline Portela Muniz, José Albuquerque Landim, Augusto César Gadelha de Abreu Filho
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Abstract Autoimmune gastritis (AIG) is a form of chronic gastritis that exhibits inflammatory cell infiltration and progressive loss of normal gastric glands. Since histology and early gastroscopy have established gastritis as a disease entity, many classifications of gastritis have been proposed. For instance, Strickland and McKay proposed a classification of atrophic gastritis into type A and type B based on etiological, functional, and localization differences1. Type A was defined as corpus‐limited...
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Abstract There is no report of detailed endoscopic diagnosis of superficial non‐ampullary duodenal epithelial tumor (SNADET) except relatively small case series. Here, we conducted a prospective observational study to investigate the relationship between endoscopic findings and histopathological diagnosis of SNADETs. A total of 163 SNADETs with magnified endoscopic examination with image‐enhanced endoscopy (IEE‐ME) those were chosen from a prospective maintained database were included in this study....
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54 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: macrophage These pubmed results were generated on 2019/09/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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