Publication date: Available online 24 September 2019Source: Free Radical Biology and MedicineAuthor(s): Keum Jin Yang, Jeong Ho Kim, Yoon Kyung Chang, Cheol Whee Park, Suk Young Kim, Yu Ah HongAbstractReactive oxygen species (ROS) play a pivotal role in the development of contrast-induced nephropathy (CIN). The inhibition of xanthine oxidoreductase is known to reduce levels of ROS. We investigated whether febuxostat could attenuate oxidative stress via the activation of adenosine monophosphate-activated...
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Publication date: Available online 23 September 2019Source: Free Radical Biology and MedicineAuthor(s): Hereward J. Wimborne, Kenji Takemoto, Patrick M. Woster, Don C. Rockey, John J. Lemasters, Zhi ZhongAbstractBackground and aimLiver fibrosis is a leading cause of mortality worldwide. Oxidative stress is a key component in the pathogenesis of liver fibrosis. We investigated the role of aldehyde formation resulting from lipid peroxidation in cholestatic liver injury and fibrosis.MethodsC57Bl/6J...
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Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Roberto Rodriguez Rubio, Ricky Chae, Ashna Khare, Todd Dubnicoff, Ethan Winkler, Emily Sloan, Andrew W. Bollen, Mitchel S. Berger, Adib A. AblaRadiation-induced telangiectasia of the central nervous system has been described predominantly in children, with up to 20% of patients affected after 3–41 years of radiotherapy.1, 2 We present the case of a 45-year-old male with a pontine pilocytic astrocytoma treated with standard-dose...
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Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Hiroshi Uda, Takehiro Uda, Kosuke Nakajo, Yuta Tanoue, Takahiro Okuno, Saya Koh, Yohei Onishi, Hiroki Ohata, Yusuke Watanabe, Ryoko Umaba, Toshiyuki Kawashima, Kenji OhataBackgroundMixed germ cell tumors (MGCTs) usually occur in children. In the present report, we discuss an extremely rare case of adult-onset MGCT composed mainly of yolk sac tumor (YST) around the pineal gland.Case DescriptionA 54-year-old Japanese man...
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Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Chirag A. BerryBackgroundOblique lumbar interbody fusion takes advantage of the wide interval between the aorta and left-sided psoas muscle to access the lumbar spine, allowing a minimally invasive approach for interbody fusion with lower associated morbidity. As this approach is gaining popularity among spine surgeons, it is important to understand the potential pitfalls that may arise in patients with congenital anomalies...
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Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Naohisa Miyakoshi, Michio Hongo, Yuji Kasukawa, Yoshinori Ishikawa, Daisuke Kudo, Yoichi ShimadaBackgroundSymptomatic calcification of the ligamentum flavum (CLF) is common in the cervical spine but rare in the thoracic spine. Rapidly progressing CLF in the thoracic spine has not been reported in the literature.Case DescriptionA 76-year-old Asian male experienced back pain after a fall and was diagnosed with osteoporotic...
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Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Laura Pradini-Santos, Claudia L. Craven, Parag P. SayalEhlers-Danlos syndrome can be associated with cerebrospinal fluid (CSF) disturbances including recurrent CSF leak and Chiari I malformations. Persistent pseudomeningoceles are known to be associated with raised intracranial pressure. We present an unusual case of a compressive epidural CSF collection occurring after a computed tomography−guided L5 nerve root block...
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Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Ralph J. Mobbs, Wen Jie Choy, Telvinderjit Singh, Lachlan Cassar, Chris Davidoff, Leigh Harris, Kevin Phan, Meinrad FiechterBackgroundIncomplete ossification of the pars interarticularis will result in a pars defect, a common cause of low back pain in youth and strongly associated with participation in high-impact sports. If left untreated, it can result in spondylolisthesis, causing dynamic canal stenosis, low back pain,...
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Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Naoto Kuroda, Chikanori Inenaga, Yoshifumi Arai, Yoshiro Otsuki, Tokutaro TanakaBackgroundImmunoglobulin (Ig)G4-related disease (IgG4-RD) was defined only recently and can be found in many organs. As intracranial lesions, hypophysitis and pachymeningitis are well known, whereas intracranial pseudotumor is unusual. This case involved multiple intracranial pseudotumors without extracranial lesions, mimicking multiple meningioma.Case...
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Complete Transection of Optic Nerve After Endovascular Coiling of a Large Ophthalmic Artery Aneurysm
Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Barbara Verbraeken, Salah-Eddine Achahbar, Niels Kamerling, Laetitia Yperzeele, Maurits Voormolen, Tony Van Havenbergh, Tomas MenovskyBackgroundWe describe a patient who developed delayed blindness of the left eye at 5 weeks after endovascular coiling of a large ophthalmic aneurysm.Case DescriptionA 44-year-old male was admitted with visual decline due to compression of the optic nerve by a large ophthalmic aneurysm....
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Publication date: Available online 23 September 2019Source: World NeurosurgeryAuthor(s): Rajesh Kumar Meena, Ramesh S. Doddamani, Hitesh K. Gurjar, Amandeep Jagdevan, Sarat P. ChandraAbstractBackgroundSplit cord malformations (SCMs) are among the rare congenital spinal anomalies. In 1992, Pang et al, proposed the “Unified theory of embryogenesis” and explained the formation of SCM type 1 and 2. This theory has been widely accepted in the neurosurgical literature, backed by several studies. However,...
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Publication date: Available online 23 September 2019Source: World NeurosurgeryAuthor(s): Min Huang, Hongrong Qian, Junsen Wang, Qiyu Zhao, Tian’an JiangAbstractSchwannoma is a tumor arising from peripheral nerve sheaths and commonly occur in the head、neck and upper and lower extremities. Schwannoma in the presacral space is relatively rare and is often misdiagnosed before pathological diagnosis is made. Here we discussed a case of giant presacral schwannoma in a 34-year-old man with emphasis on imaging...
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Publication date: Available online 24 September 2019Source: Journal of Genetics and GenomicsAuthor(s): Jing Zhang, Ji-Long LiuAbstractThe metabolic enzyme CTP synthase (CTPS) is able to compartmentalize into filaments, termed cytoophidia, in a variety of organisms including bacteria, budding yeast, fission yeast, fruit flies and mammals. A previous study in budding yeast shows that the filament-forming process of CTPS is not sensitive to temperature shift. Here we study CTPS filamentation in the...
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Publication date: November 2019Source: Journal of Phonetics, Volume 77Author(s): Antje SchweitzerAbstractThis article explores an exemplar-theoretic approach to the integration of phonetics and phonology in the prosodic domain. In an exemplar-theoretic perspective, prominence categories, here specifically, pitch-accented syllables and unaccented syllables, are assumed to correspond to accumulations of similar exemplars in an appropriate perceptual space. It should then be possible, as suggested for...
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Publication date: November 2019Source: Journal of Phonetics, Volume 77Author(s): Suyeon Yun, Yoonjung KangAbstractThis study examines the phonetic variation of the word-initial liquid in two dialects of Korean, Northern Hamkyeong Korean of North Korea and Seoul Korean of South Korea. The goals of the study are two-fold: to provide a thorough description of the phonetic variation in the word-initial liquid in these two dialects and to examine the acquisition of Seoul Korean features by North Koreans...
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Background: Poikilodermatous mycosis fungoides (pMF) is characterized by poikiloderma areas, typically involving the major flexural areas and trunk. Its presentation can be generalized or admixed with other forms of MF. Previous studies fail to correlate the clinical presentation with prognosis and laboratory findings. Some reports show pityriasis lichenoides chronica (PLC) preceding the poikiloderma. Objectives: Correlate prognostic, histopathological and molecular aspects of pMF with its clinical...
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Related ArticlesComparison of Temporalis Fascia and Transcanal Composite Chondroperichondrial Tympanoplasty Techniques. Ear Nose Throat J. 2019 Sep 23;:145561319875663 Authors: Gozeler MS, Sahin A Abstract The purpose of this study was to compare the success rates and hearing outcomes of transcanal composite chondroperichondrial cartilage graft with that of underlay temporal muscle fascia (TMF) graft for myringoplasty. In this retrospective study, the...
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Related ArticlesPlasma Cell Mucositis of the Hard Palate. Ear Nose Throat J. 2019 Sep 23;:145561319872732 Authors: Micucci SB, Zim SA, Hosfield EM PMID: 31544489 [PubMed - as supplied by publisher]
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Publication date: Available online 23 September 2019Source: Journal of VoiceAuthor(s): Karen M. Crow, Miriam van Mersbergen, Alexis E. PayneSummaryVoices are, by nature, idiosyncratic representations of individuals because they possess anatomical, physiological, and psychological characteristics that are unique to them, which contribute to vocal output, and thus, establish the voice as a salient marker of their individuality. The areas of experimental psychology and cognitive neuroscience have examined...
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Publication date: Available online 23 September 2019Source: Journal of VoiceAuthor(s): Jérôme R. Lechien, Kathy Huet, Camille Finck, Serge Blecic, Véronique Delvaux, Myriam Piccaluga, Sven Saussez, Bernard HarmegniesSummaryObjectiveAcoustic parameters are widely used as voice quality therapeutic outcomes in many laryngological diseases. The aim of this study is to explore the impact of changes in the nature and duration of the analyzed time interval and the vowel choice on the significance of the...
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Publication date: Available online 23 September 2019Source: Journal of VoiceAuthor(s): Necati Enver, Can Doruk, Erdogan Kara, Kamber Kaşali, Hızır Asliyuksek, Bora BasaranSummaryObjectiveLaryngeal framework surgery has been a topic of interest since last decades. To succeed with least morbidity, the most important step is mastering the anatomy of larynx. In this study, we aim to show the relation between body height and laryngeal morphometrics that are important during laryngeal framework surgeries.Data...
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Publication date: Available online 23 September 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): William W. Busse
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Publication date: Available online 23 September 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Marissa Hauptman, Jonathan M. Gaffin, Carter R. Petty, William.J. Sheehan, Peggy S. Lai, Brent Coull, Diane R. Gold, Wanda PhipatanakulAbstractObjectiveTo use spatial analysis methodology to analyze residential and school proximity to major roadways and pediatric asthma morbidity.MethodsThe School Inner-City Asthma Study (n=350) recruited school-aged children with asthma. Each participant’s...
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Publication date: Available online 23 September 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Steve N. Georas
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Introduction: Brush cytology is commonly used during endoscopic retrograde cholangiopancreatography for the diagnostic evaluation of biliopancreatic strictures. However, since the overall sensitivity of brush cytology is poor, the exclusion of malignancy is difficult. Recognition of factors related to the patient, technique or lesion may help improve the diagnostic yield of brush cytology. The objective of this study was to evaluate the diagnostic yield of brush cytology in the assessment of biliopancreatic...
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Background: Infertility is an ever-increasing problem in today’s world. It can be due to male or female causes. Azoospermia seen in 5–10% of infertile men is due to obstructive or non-obstructive causes. Traditionally, testicular biopsy is the gold standard for evaluation. Fine-needle aspiration (FNA), however, is minimally invasive, provides qualitative and quantitative information about spermatogenesis, and can aid in assisted reproductive techniques making it a novel technique for the evaluation...
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Publication date: Available online 23 September 2019Source: European Journal of RadiologyAuthor(s): Felix Harder, Fabian K. Lohöfer, Georgios A. Kaissis, Christoph Zoellner, Omar Kamal, Christoph Katemann, Andreas Hock, Julien Senegas, Johannes M. Peeters, Ernst J. Rummeny, Dimitrios Karampinos, Rickmer F. BrarenAbstractPurposeTo evaluate the performance of a novel camera-based breathing navigation system in respiratory-triggered (CRT) 3D-magnetic resonance cholangiopancreatography (MRCP) at 3 T...
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Related ArticlesDevelopment and Clinical Introduction of the Nurotron Cochlear Implant Electrode Array. J Int Adv Otol. 2018 Dec;14(3):392-400 Authors: Rebscher S, Zhou DD, Zeng FG Abstract As the only medical device used in the treatment for deafness, the cochlear implant has benefited to more than half a million individuals worldwide. However, the device has limited penetration due to its high cost, especially in low- and middle-income countries....
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Related ArticlesInteraural Time Difference Perception with a Cochlear Implant and a Normal Ear. J Assoc Res Otolaryngol. 2018 12;19(6):703-715 Authors: Francart T, Wiebe K, Wesarg T Abstract Currently there is a growing population of cochlear-implant (CI) users with (near) normal hearing in the non-implanted ear. This configuration is often called SSD (single-sided deafness) CI. The goal of the CI is often to improve spatial perception, so the question...
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Related ArticlesEvaluation of Possible Effects of a Potassium Channel Modulator on Temporal Processing by Cochlear Implant Listeners. J Assoc Res Otolaryngol. 2018 12;19(6):669-680 Authors: Carlyon RP, Deeks JM, Guérit F, Lamping W, Billig AJ, Large CH, Saeed SR, Harris P Abstract Temporal processing by cochlear implant listeners is degraded and is affected by auditory deprivation. The fast-acting Kv3.1 potassium channel is important for sustained...
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Related ArticlesMulticenter US Clinical Trial With an Electric-Acoustic Stimulation (EAS) System in Adults: Final Outcomes. Otol Neurotol. 2018 03;39(3):299-305 Authors: Pillsbury HC, Dillon MT, Buchman CA, Staecker H, Prentiss SM, Ruckenstein MJ, Bigelow DC, Telischi FF, Martinez DM, Runge CL, Friedland DR, Blevins NH, Larky JB, Alexiades G, Kaylie DM, Roland PS, Miyamoto RT, Backous DD, Warren FM, El-Kashlan HK, Slager HK, Reyes C, Racey AI, Adunka OF Abstract...
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Related ArticlesPreauricular Approach for Cholesteatoma Resection After Surgical Overclosure of the External Auditory Canal and Cochlear Implantation. Otol Neurotol. 2018 03;39(3):318-319 Authors: Telian SA Abstract : Chronic suppurative otitis media can have long-term effects on hearing if not managed effectively. When combined with cholesteatoma the condition may require creation of an open mastoid cavity. Recurrence of cholesteatoma is a concern...
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Related ArticlesVestibular Outcome After Cochlear Implantation Is Not Related to Surgical Technique: A Double Blinded, Randomized Clinical Trial of Round Window Approach Versus Cochleostomy. Otol Neurotol. 2018 03;39(3):306-312 Authors: Korsager LEH, Schmidt JH, Faber C, Wanscher JH Abstract OBJECTIVE: To establish whether the round window approach (RWA) leads to less vestibular dysfunction and dizziness than the standard cochleostomy approach (SCA)...
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People with gum disease (periodontitis) have a greater likelihood of high blood pressure (hypertension), according to a new study.
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37 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Radiother Oncol These pubmed results were generated on 2019/09/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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37 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Radiother Oncol These pubmed results were generated on 2019/09/24PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Nature Reviews Immunology, Published online: 24 September 2019; doi:10.1038/s41577-019-0226-4Chimeric antigen receptor (CAR) T cells directed at fibroblast activation protein show efficacy in mouse models of hypertensive cardiac injury and fibrosis.
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Nature Reviews Immunology, Published online: 24 September 2019; doi:10.1038/s41577-019-0227-3Antibiotics can impair the development of immunity against seasonal influenza virus in individuals with low levels of pre-existing immune memory.
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