Vaccination with a Single-Cycle Respiratory Syncytial Virus Is Immunogenic and Protective in Mice [IMMUNOTHERAPY AND VACCINES]

The Journal of Immunology by Schmidt, M. E., Oomens, A. G. P., V.. - 1w ago Preview

 
 
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Key Points

The live-attenuated, single-cycle RSV M-null vaccine is significantly attenuated.

RSV M-null vaccination in mice induces robust acute and memory immune responses.

Vaccination with RSV M-null provides protection against secondary viral challenge.

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