The effect of TopClosure® TRS in the treatment of large abdominal wall defect

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Abstract Background

Large abdominal wall defects, which are not suitable for primary closure partly due to the expected high tension closure and the considerable rate of recurrence, represent a substantial reconstructive challenge. The study is aimed to evaluate the clinical value of TopClosure® Tension-Relief System (TRS) in the treatment of large abdominal wall defect.

Methods

Thirteen patients with large abdominal wall defect were treated using TopClosure® TRS, and the average healing time, patients’ satisfaction, and complication were recorded.

Results

After being treated with TopClosure® TRS, 10 cases were primary healing, three-case second-intention healing due to the thickened abdominal wall with mild scar. The average healing time and hospitalization time are shortened, while the primary healing rate and VAS satisfactory value improved. Logistic regression analyses indicated that age, BMI, defect area, wound infection, and diabetes may influence the effect of TopClosure® TRS in the repair of large abdominal wall defect.

Conclusion

Large abdominal wall defect can be treated using TopClosure® TRS, effectively and easily, which can be generalized to be used in clinics.

Level of evidence: Level IV, therapeutic study.