Given the lack of research on the schoolchildren exposure to PM2.5-bound PHAs in northeast China, we investigated the effects of exposure to ambient benzo[b]fluoranthene (BbFA) and dibenz[a,h]anthracene (DahA) bound to PM2.5 on pulmonary ventilation dysfunction (PVD) and small airway dysfunction (SAD). PM2.5 samples at two schools (A and B) were collected, and the concentrations of PM2.5-bound 4–6-ring PAHs were analyzed. PVD and SAD were evaluated by pulmonary function tests in 306 students while...
Tue Sep 24, 2019 11:05
Background. Stigma related to mental illness can be an obstacle affecting the quality of life of people with mental illness. Although mental illness in the workplace is a public problem globally, few studies have investigated the effect of stigma on job-related problems such as burnout. Aim. This study aimed to clarify the association between mental-illness-related stigma and burnout among nonprofessional occupational mental health staff. Methods. In this cross-sectional study, nonprofessional occupational...
Tue Sep 24, 2019 12:05
Background. The syndrome of drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare, yet potentially fatal hypersensitivity reaction, most commonly associated with anticonvulsants, sulfonamides, and allopurinol. The reaction commonly manifests as a febrile skin eruption with lymphadenopathy and malaise between two and eight weeks following drug exposure. Internal organ involvement occurs in close to 90 percent of patients, and multiple organs may be involved in approximately half...
Tue Sep 24, 2019 12:05
This study aimed at investigating the effect of occupational health and safety (OHS) on employee’s turnover intention (TI) with the mediating effect of organizational commitment (OC) in the Ghanaian power industry. Methods. With stratified sampling technique, 350 participants were selected to participate in the study with standardized quantitative questionnaires to measure the variables involved in the study and SmartPLS 3-structural equation modeling technique to analyze the data. Results. The results...
Tue Sep 24, 2019 16:05
Bacteria in biofilms are encased in an extracellular polymeric matrix that limits exposure of microbial cells to lethal doses of antimicrobial agents, leading to resistance. In Pseudomonas aeruginosa, biofilm formation is regulated by cell-to-cell communication, called quorum sensing. Quorum sensing facilitates a variety of bacterial physiological functions such as swarming motility and protease, pyoverdine, and pyocyanin productions. Peptide mix from the marine mollusc, Olivancillaria hiatula, has...
Tue Sep 24, 2019 16:05
Globe artichoke is an intriguing source of indigestible sugar polymers such as inulin-type fructans. In this study, the effect of ultrasound in combination with ethanol precipitation to enhance the extraction of long chain fructans from artichoke wastes has been evaluated. The inulin-type fructans content both from bracts and stems was measured using an enzymatic fructanase-based assay, while its average degree of polymerization (DP) was determined by HPLC-RID analysis. Results show that this method...
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The main objective of this research was to evaluate the efficacy of intermittent hypoxic training (IHT) on aiming performance and aerobic capacity in biathletes. Fourteen male biathletes were randomly divided into a hypoxia group (H) (n = 7), which trained three times per week in a normobaric hypoxic environment (FiO2 = 16.5%, 2000 m a.s.l.) with lactate threshold intensity (LT) determined in hypoxia, and a control group (C) (n = 7), which exercised under normoxic conditions with LT intensity determined...
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Objectives. The importance of preventive medicine in an aging society is increasing. Locomotive syndrome (LS) is attracting increasing attention. Recently, advances in bioelectrical impedance analysis (BIA) devices have made it possible to automatically measure waist circumference (WC). Nevertheless, there have been no reports evaluating the agreement or interchangeability between WC measured manually and using BIA. Therefore, we aimed to perform these analyses in the context of health checkups and...
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J Neurol Surg BDOI: 10.1055/s-0039-1697026 Objective The main purpose of this article is to determine if vestibular schwannoma consistency as determined by tissue intensity on T2-weighted magnetic resonance imagings (MRIs) is predictive of intraoperative experience and postoperative clinical outcomes. Study Design Retrospective chart review. Setting Tertiary referral center. Patients Seventy-seven patients diagnosed with vestibular schwannomas who were...
Tue Sep 24, 2019 02:00
Tue Sep 24, 2019 03:00
British Journal of Cancer, Published online: 24 September 2019; doi:10.1038/s41416-019-0592-5Correction: Long-term outcomes of the GPOH NB97 trial for children with high-risk neuroblastoma comparing high-dose chemotherapy with autologous stem cell transplantation and oral chemotherapy as consolidation
Tue Sep 24, 2019 03:00
British Journal of Cancer, Published online: 24 September 2019; doi:10.1038/s41416-019-0591-6Correction: Desperately seeking…Models to find the right partner and the best use for checkpoint inhibitors
Tue Sep 24, 2019 03:00
British Journal of Cancer, Published online: 25 September 2019; doi:10.1038/s41416-019-0586-3Systemic MEK inhibition enhances the efficacy of 5-aminolevulinic acid-photodynamic therapy
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British Journal of Cancer, Published online: 25 September 2019; doi:10.1038/s41416-019-0580-9Type 2 diabetes mellitus, blood cholesterol, triglyceride and colorectal cancer risk in Lynch syndrome
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Fermentation of chemicals from lignocellulose hydrolysate is an effective way to alleviate environmental and energy problems. However, fermentation inhibitors in hydrolysate and weak inhibitor tolerance of mic...
Tue Sep 24, 2019 03:00
Purpose: Photoacoustic imaging (PAI) is a novel non-invasive non-ionising imaging technique that allows longitudinal imaging of tumor vasculature in vivo and monitoring of response to therapy, especially for vascular targeted chemotherapy agents. In this study we used a novel high resolution all optical PAI scanner to observe the pharmacodynamic response to the vascular disrupting agent OXi4503. Experimental Design: two models of colorectal carcinoma (SW1222 and LS174T) that possess differing pathophysiological...
Tue Sep 24, 2019 16:58
Related ArticlesToo Many Avoidable Suicides Occur Worldwide in Young Patients. Rambam Maimonides Med J. 2019 Sep 18;: Authors: Rose K, Neubauer D, Grant-Kels JM Abstract United States (US) and European Union (EU) laws attempt to counterbalance the presumed discrimination of children in drug treatment and drug development. The US Food and Drug Administration (FDA)-rewarded pediatric studies with antidepressants triggered in 2004 an FDA black-box warning...
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A delicate relationship exists between reef-building corals and their photosynthetic endosymbionts. Unfortunately, this relationship can be disrupted, with corals expelling these algae when temperatures rise even marginally above the average summer maximum. Interestingly, several studies indicate that failure of corals to regulate symbiont cell divisions at high temperatures may underlie this disruption; increased proliferation of symbionts may stress host cells by over-production of reactive oxygen...
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Poecilia reticulata is one of the most popular ornamental fish species with a higher demand for males due to their large colorful fins. The objectives of this study were mapping of the sex-determining (SD) region on linkage group 12 of guppy, and identification of a sex specific marker. We generated eight polymorphic microsatellite markers distributed along the distal 5.4 Mbp sequence of the previously identified SD region on linkage group (LG) 12. The markers were tested for association with sex...
00:18
NEAT1 is one of the most studied lncRNAs, in part because its silencing in mice causes defects in mammary gland development and corpus luteum formation, and protects them from skin cancer development. Moreover, depleting NEAT1 in established cancer cell lines reduces growth and sensitizes cells to DNA damaging agents. However, NEAT1 produces two isoforms and because the short isoform, NEAT1_1, completely overlaps the 5' part of the long NEAT1_2 isoform, the respective contributions of each of the...
Tue Sep 24, 2019 18:24
There is a pressing need for nucleic acid-based assays that are capable of rapidly and reliably detecting pathogenic organisms. Many of the techniques available for the detection of pathogenic RNA possess one or more limiting factors that make the detection of low-copy RNA challenging. While RT-PCR is the most commonly used method for detecting pathogen-related RNA, it requires expensive thermocycling equipment and is comparatively slow. Isothermal methods promise procedural simplicity, but have...
Tue Sep 24, 2019 22:29
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01458F, PaperJian Liu, Fuzhong Ouyang, Tianrong Yu, Chao Gu, Guanghui Wang, Rui Shi, Rui Lv, Enhui Wu, Chongqing Ma, Ruochen Guo, Jing Li, Anna ZaczekThere is a great need to develop sensitive and specific methods for quantitative analysis of caspase-3 activities in cell apoptosis. Herein, we report a new method for sensitive detection of...The content of this RSS Feed (c) The Royal Society of Chemistry
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Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01606F, PaperJie Gao, Yingxu Chen, Weihao Ji, Zhonghong Gao, Jingdong ZhangA composite of CdS nanoparticles and europium metal organic framework (Eu-MOF) (CdS/Eu-MOF) was synthesized. The unique property of MOF helps to improve the photoelectrochemical (PEC) property of CdS by reducing...The content of this RSS Feed (c) The Royal Society of Chemistry
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