Ângela Roda, Ana Marcos-Pinto, Rita Pimenta, João Maia-SilvaJournal of Cutaneous and Aesthetic Surgery 2019 12(3):201-202
Ashish Chauhan, Sukhbir SinghJournal of Cutaneous and Aesthetic Surgery 2019 12(3):183-186Facial fillers are minimally invasive aesthetic procedures performed for facial rejuvenation and contouring all over the world. Fillers even in the most experienced hands can lead to fatal complications such as vascular complications that need to be managed immediately with the help of hyaluronidase protocols mentioned in literature. In this case report, a patient was asymptomatic with no signs of vascular occlusion...
CP Thajudheen, Kannangath Jyothy, Priyadarshini ArulJournal of Cutaneous and Aesthetic Surgery 2019 12(3):193-195Xanthelasma palpebrarum,a benign xanthoma occurring around the eyes ,are treated using lasers like carbon dioxide, argon, pulsed dye, YAG, and diode(1450) laser .Several studies on PDL for xanthelasma palpebrarum (XP) have been reported from abroad but as per our knowledge there are no Indian studies in this regard. We report the efficacy of pulsed dye laser in the management of xanthelasma...
Mohamed Soliman, Sidharth Sonthalia, Akmal Saad, Mohamed Elkomy, Mohamed Abdelhady, Gaurang KrishnaJournal of Cutaneous and Aesthetic Surgery 2019 12(3):179-182Correction of depigmentation of postburn leukodermic scars is daunting. In contrast to vitiligo, the success rate of skin grafting techniques is much lower in postburn scars owing to altered skin architecture and poor graft uptake. Cellular transfer techniques such as noncultured epidermal or epidermal or keratinocyte suspension suffer the...
Gurunathampalayam Ilango Nambi, Thirumurugan Kavin Arudhra VaranambigaiJournal of Cutaneous and Aesthetic Surgery 2019 12(3):187-190Objective: The aim of this study was to present an underutilized and underreported surgical technique in which the glomus tumors situated anywhere under the nail bed can be approached and removed with relative ease. Materials and Methods: Over 3 years, four cases of subungual glomus tumors, which were surgically managed with this technique were presented. The technical...
Ashish Jagati, Raju G Chaudhary, Santoshdev P Rathod, Bhushan Madke, Kalgi D Baxi, Dixit KasundraJournal of Cutaneous and Aesthetic Surgery 2019 12(3):174-178Introduction: Platelet-rich fibrin (PRF) is compressed by using various tools to make platelet-rich fibrin membrane (PRFM). Preservation of platelets and plasma content of PRFM depends on the compression method used. To overcome limitations of compression method, we prepared PRFM over scaffold of collagen sheet without using any compression...
Gulhima Arora, Sandeep AroraJournal of Cutaneous and Aesthetic Surgery 2019 12(3):196-200
Gianfranco M Colicchia, Verdiana Di Pietro, Valerio CervelliJournal of Cutaneous and Aesthetic Surgery 2019 12(3):164-173Context: After massive weight loss, breast changes dramatically becoming ptotic, flat in the upper pole, with significant skin excess. After mastoplasty, often ptosis can recur and the upper pole can lose its fullness again. The technique described in this study treats breast deformities ensuring stable results and avoiding ptosis recurrence. Aim: To analyze a new modality of breast...
Enas Shuber, Dalia Abdulhussein, Pierre Sinclair, Murtaza KadhumJournal of Cutaneous and Aesthetic Surgery 2019 12(3):153-157Background: The incidence of melanoma and nonmelanoma skin cancers is increasing in the United Kingdom. Surgical excision carries the highest cure rates for all skin cancers and is the first-line treatment for melanomas and high-risk nonmelanoma cancers. This is most commonly performed by general practitioners (GPs), dermatologists, and plastic surgeons. Objective: The aim...
Rashmi Sarkar, Sneha Ghunawat, Vijay Kumar GargJournal of Cutaneous and Aesthetic Surgery 2019 12(3):158-163Background: Acne is a commonly encountered disorder in the dermatological practice. Chemical peeling is one of the treatment modalities in acne and postacne pigmentation. Although various peeling agents are available, studies comparing their efficacy are lacking. Moreover, there is a paucity of studies comparing the efficacy of combination peels in Asian population. Materials and Methods: Forty-five...
Uwe WollinaJournal of Cutaneous and Aesthetic Surgery 2019 12(3):191-192Dermatosurgery is a growing subspeciality due to increasing numbers of skin cancer and aesthetic procedures. Patient safety is a major issue in dermatosurgery. Quality management, education, and organization are the backbone of patient safety. A simple measure to support patient’s safety and to avoid wrong site surgery is preoperative skin marking. Permanent skin markers offer a painless and cost-effective option. To ensure optimal...
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Analytical ChemistryDOI: 10.1021/acs.analchem.9b02238
Analytical ChemistryDOI: 10.1021/acs.analchem.9b02178
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03534
Analytical ChemistryDOI: 10.1021/acs.analchem.9b02631
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03453
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03642
Analytical ChemistryDOI: 10.1021/acs.analchem.9b04059
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03410
Analytical ChemistryDOI: 10.1021/acs.analchem.9b02887
Analytical ChemistryDOI: 10.1021/acs.analchem.9b02994
Analytical ChemistryDOI: 10.1021/acs.analchem.9b00895
Analytical ChemistryDOI: 10.1021/acs.analchem.9b02728
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03227
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Beta satellite DNA (satDNA), also known as Sau3A sequences, are repeated DNA sequences reported in human and primate genomes. It is previously thought that beta satDNAs originated in old world monkeys and bursted in great apes. In this study, we searched 7,821 genome assemblies of 3,767 eukaryotic species and found that beta satDNAs are widely distributed across eukaryotes. The four major branches of eukaryotes, animals, fungi, plants and Harosa/SAR, all have multiple clades containing beta satDNAs....
The number of mutations that occur per nucleotide per generation varies between species by several orders of magnitude. In multicellular eukaryotes, the per generation mutation rate depends both on the per cell division mutation rate and on the number of germline cell divisions per generation. In a range of species, from fungi to humans, the number of germline cell divisions is lower than that of somatic cells, reducing the mutation burden on the offspring. The basidiomycete Schizophyllum commune...
Regulatory changes are broadly accepted as key drivers of phenotypic divergence. However, identifying regulatory changes that underlie human-specific traits has proven very challenging. Here, we use 63 DNA methylation maps of ancient and present-day humans, as well as of six chimpanzees, to detect differentially methylated regions that emerged in modern humans after the split from Neanderthals and Denisovans. We show that genes affecting the face and vocal tract went through particularly extensive...
In diverse organisms, nanostructures that coherently scatter light create structural color, but how such structures are built remains mysterious. We investigate the evolution and genetic regulation of butterfly scale laminae, which are simple photonic nanostructures. In a lineage of buckeye butterflies artificially selected for blue wing color, we found that thickened laminae caused a color shift from brown to blue. Deletion of the optix wing patterning gene also altered color via lamina thickening,...
The current influenza A antigenic evolution paradigm suggesting that antigenic evolution is highly constrained, with successful new viruses being near optimal at maximizing their antigenic distance from past strains. This begs the question of whether influenza antigenic evolution is fundamentally predictable, or if it takes place on a much higher dimensional antigenic space with multiple possible trajectories. We tackle this issue by building a genotype to phenotype map validated on historical hemagglutination...
The loss of functions required for independent life when living within a host gives rise to reduced genomes in obligate bacterial symbionts. Although this phenomenon can be explained by existing evolutionary models, its initiation is not well understood. Here, we describe the microbiome associated with eggs of the beetle Lagria villosa, containing multiple bacterial symbionts related to Burkholderia gladioli including a reduced-genome symbiont thought to produce the defensive compound lagriamide....
This report details current seasonal influenza circulation patterns as of August 2019 and makes projections up to September 2020 to coincide with selection of the 2020 Southern Hemisphere vaccine strain. This is not meant as a comprehensive report, but is instead intended as particular observations that we've made that may be of relevance. Please also note that observed patterns reflect the GISAID database and may not be entirely representative of underlying dynamics. All analyses are based on the...
Sexual maturation is a pivotal life-history trait that balances the probabilities between mortality and reproduction. Environmental vs. genetic contributions to maturation component traits, such as somatic growth and body condition, remain uncertain because of difficulties in determining causality. In Atlantic salmon, maturation timing associates with a large-effect locus around vgll3, which also links with growth, condition, and maturation in mammals. We investigate environmental vs. genetic contributions...
Landscape genomics studies focus on identifying candidate genes under selection via spatial variation in abiotic environmental variables, but rarely by biotic factors such as disease. The Tasmanian devil (Sarcophilus harrisii) is found only on the environmentally heterogeneous island of Tasmania and is threatened with extinction by a nearly 100% fatal, transmissible cancer, devil facial tumor disease (DFTD). Devils persist in regions of long-term infection despite epidemiological model predictions...
In a previous study, the authors utilized a single dimensional operationalization of species density that at least partially demonstrated dynamic system behavior. For completeness, a theory needs to be developed related to homology/cohomology, induction of the time dimension, and system hierarchies. The topological nature of the system is carefully examined and for testing purposes, species density data for a wild Dictyostelia community data are used in conjunction with data derived from liquid-chromatography...
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