JCM, Vol. 8, Pages 1480: Association between Achievement of Estimated Average Glucose Level and 6-Month Neurologic Outcome in Comatose Cardiac Arrest Survivors: A Propensity Score-Matched Analysis Journal of Clinical Medicine doi: 10.3390/jcm8091480 Authors: Yong Hun Jung Byung Kook Lee Kyung Woon Jeung Dong Hun Lee Hyoung Youn Lee Yong Soo Cho Chun Song Youn Jung Soo Park Yong II Min We investigated whether achieving estimated average glucose (EAG) levels versus...
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JCM, Vol. 8, Pages 1479: Disseminated Well-Differentiated Gastro-Entero-Pancreatic Tumors Are Associated with Metabolic Syndrome Journal of Clinical Medicine doi: 10.3390/jcm8091479 Authors: Santos Castro Antunes Henrique Cardoso Monteiro The association of well-differentiated gastro-entero-pancreatic neuroendocrine tumors (WD GEP-NETs) with metabolic syndrome (MetS), abdominal obesity, and fasting glucose abnormalities was recently described. The aim of this study...
Tue Sep 17, 2019 03:00
JCM, Vol. 8, Pages 1478: Blood-Based Treatments for Severe Dry Eye Disease: The Need of a Consensus Journal of Clinical Medicine doi: 10.3390/jcm8091478 Authors: Federico Bernabei Matilde Roda Marina Buzzi Marco Pellegrini Giuseppe Giannaccare Piera Versura The use of blood-based eye drops as therapy for various diseases of the ocular surface has become increasingly popular in ophthalmic practice during recent years. The rationale for their use is based on the promotion...
Tue Sep 17, 2019 03:00
JCM, Vol. 8, Pages 1477: BK Polyomavirus Virus Glomerular Tropism: Implications for Virus Reactivation from Latency and Amplification during Immunosuppression Journal of Clinical Medicine doi: 10.3390/jcm8091477 Authors: Donald J. Alcendor BK polyomavirus (BKPyV), or BKV infection, is ubiquitous and usually non-pathogenic, with subclinical infections in 80–90% of adults worldwide. BKV infection is often associated with pathology in immunocompromised individuals. BKV infection...
Tue Sep 17, 2019 03:00
JFB, Vol. 10, Pages 43: Striking Differences in Platelet Distribution between Advanced-Platelet-Rich Fibrin and Concentrated Growth Factors: Effects of Silica-Containing Plastic Tubes Journal of Functional Biomaterials doi: 10.3390/jfb10030043 Authors: Tetsuhiro Tsujino Hideo Masuki Masayuki Nakamura Kazushige Isobe Hideo Kawabata Hachidai Aizawa Taisuke Watanabe Yutaka Kitamura Hajime Okudera Kazuhiro Okuda Koh Nakata Tomoyuki Kawase Compared with platelet-rich...
Tue Sep 17, 2019 03:00
JoF, Vol. 5, Pages 86: Diagnostic Performance of a Novel Multiplex PCR Assay for Candidemia among ICU Patients Journal of Fungi doi: 10.3390/jof5030086 Authors: Fuchs Lass-Flörl Posch Candidemia poses a major threat to ICU patients and is routinely diagnosed by blood culture, which is known for its low sensitivity and long turnaround times. We compared the performance of a novel, Candida-specific multiplex real-time PCR assay (Fungiplex® Candida IVD Real-Time PCR Kit)...
Tue Sep 17, 2019 03:00
Medicina, Vol. 55, Pages 600: Relationship Between Serum Uric Acid Levels and Nonalcoholic Fatty Liver Disease in Non-Obese Patients Medicina doi: 10.3390/medicina55090600 Authors: Oral Sahin Turker Kocak Background and objectives: Nonalcoholic fatty liver disease (NAFLD) is associated with multiple factors such as hypertension, diabetes, dyslipidemia, obesity, and hyperuricemia. We aim to investigate the relationship between uric acid and NAFLD in a non-obese and young...
Tue Sep 17, 2019 03:00
Medicina, Vol. 55, Pages 601: An Overview of the Cardiorespiratory Hypothesis and Its Potential Contribution to the Care of Neurodegenerative Disease in Africa Medicina doi: 10.3390/medicina55090601 Authors: Agbangla Fraser Albinet One hypothesis that could explain the beneficial effects of physical exercise on cognitive function is the cardiorespiratory hypothesis. This hypothesis proposes that improved cognitive functioning may be in part a result of the physiological processes...
Tue Sep 17, 2019 03:00
Medicina, Vol. 55, Pages 599: The Association of Obstructive Sleep Apnea Syndrome and Accident Risk in Heavy Equipment Operators Medicina doi: 10.3390/medicina55090599 Authors: Hakan Celikhisar Gulay Dasdemir Ilkhan Background and Objectives: Obstructive sleep apnea syndrome (OSAS) is the most frequent sleep disorder, characterized by the repeated collapse of the upper respiratory tract during sleep. In this study, we aimed to determine the prevalence of OSAS in heavy equipment operators...
Tue Sep 17, 2019 03:00
Medicina, Vol. 55, Pages 598: Gallstone Ileus: Management and Clinical Outcomes Medicina doi: 10.3390/medicina55090598 Authors: Matas Jakubauskas Raminta Luksaite Audrius Sileikis Kestutis Strupas Tomas Poskus Background: Gallstone or biliary ileus is a late complication of gallstone disease. It accounts for 1%–4% of all bowel obstructions and is more common in elderly patients. The preferred treatment option is to mechanically remove the impacted stones. It is...
Tue Sep 17, 2019 03:00
Membranes, Vol. 9, Pages 121: Characterization of the Initial Fouling Layer on the Membrane Surface in a Membrane Bioreactor: Effects of Permeation Drag Membranes doi: 10.3390/membranes9090121 Authors: Shengli Wang Xin Lu Lanhe Zhang Jingbo Guo Haifeng Zhang In this study, the properties of the initial fouling layer on the membrane surface of a bioreactor were investigated under different operating modes (with or without permeate flux) to improve the understanding of the...
Tue Sep 17, 2019 03:00
Metabolites, Vol. 9, Pages 188: 2-Deoxy-d-Glucose-Induced Metabolic Alteration in Human Oral Squamous SCC15 Cells: Involvement of N-Glycosylation of Axl and Met Metabolites doi: 10.3390/metabo9090188 Authors: Naeun Lee Won-Jun Jang Ji Hae Seo Sooyeun Lee Chul-Ho Jeong One of the most prominent hallmarks of cancer cells is their dependency on the glycolytic pathway for energy production. As a potent inhibitor of glycolysis, 2-deoxy-d-glucose (2DG) has been proposed for cancer...
Tue Sep 17, 2019 03:00
Metabolites, Vol. 9, Pages 187: R-MetaboList 2: A Flexible Tool for Metabolite Annotation from High-Resolution Data-Independent Acquisition Mass Spectrometry Analysis Metabolites doi: 10.3390/metabo9090187 Authors: Manuel D. Peris-Díaz Shannon R. Sweeney Olga Rodak Enrique Sentandreu Stefano Tiziani Technological advancements have permitted the development of innovative multiplexing strategies for data independent acquisition (DIA) mass spectrometry (MS). Software solutions...
Tue Sep 17, 2019 03:00
Microorganisms, Vol. 7, Pages 360: Characterization of Streptomyces sporangiiformans sp. nov., a Novel Soil Actinomycete with Antibacterial Activity against Ralstonia solanacearum Microorganisms doi: 10.3390/microorganisms7090360 Authors: Junwei Zhao Liyuan Han Mingying Yu Peng Cao Dongmei Li Xiaowei Guo Yongqiang Liu Xiangjing Wang Wensheng Xiang Ralstonia solanacearum is a major phytopathogenic bacterium that attacks many crops and other plants around the world....
Tue Sep 17, 2019 03:00
Molecules, Vol. 24, Pages 3387: Molecular Docking and Dynamics Simulation of Protein β-Tubulin and Antifungal Cyclic Lipopeptides Molecules doi: 10.3390/molecules24183387 Authors: Nubia Noemi Cob-Calan Luz America Chi-Uluac Filiberto Ortiz-Chi Daniel Cerqueda-García Gabriel Navarrete-Vázquez Esaú Ruiz-Sánchez Emanuel Hernández-Núñez To elucidate interactions between the antifungal cyclic lipopeptides iturin A, fengycin, and surfactin produced by Bacillus bacteria and...
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Molecules, Vol. 24, Pages 3386: Antifungal Effects and Potential Mechanism of Essential Oils on Collelotrichum gloeosporioides In Vitro and In Vivo Molecules doi: 10.3390/molecules24183386 Authors: Dan Wang Jing Zhang Xiaoman Jia Li Xin Hao Zhai The development of natural essential oil as an alternative to synthetic chemicals in the control of postharvest decay is currently in the spotlight. In the present study, the efficacy of seven essential oils in suppressing Collelotrichum...
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Molecules, Vol. 24, Pages 3385: Cytotoxicity and Apoptosis Induction of Coumarins and Carbazole Alkaloids from Clausena Harmandiana Molecules doi: 10.3390/molecules24183385 Authors: Porntip Jantamat Natthida Weerapreeyakul Ploenthip Puthongking Seven compounds, carbazole alkaloids (heptaphylline, 7-methoxyheptaphylline, 7-methoxymukonal) and coumarins (clausarin, dentatin, nordentatin, and xanthoxyletin), were isolated from the root bark of Clausena harmandiana. Antioxidation,...
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Molecules, Vol. 24, Pages 3384: Accramycin A, a New Aromatic Polyketide, from the Soil Bacterium, Streptomyces sp. MA37 Molecules doi: 10.3390/molecules24183384 Authors: Maglangit Fang Leman Soldatou Ebel Kyeremeh Deng Drug-like molecules are known to contain many different building blocks with great potential as pharmacophores for drug discovery. The continued search for unique scaffolds in our laboratory led to the isolation of a novel Ghanaian soil bacterium,...
Tue Sep 17, 2019 03:00
Molecules, Vol. 24, Pages 3382: Electrical and Electrochemical Behavior of Carbon Paste Electrodes Modified with Ionic Liquids Based in N-Octylpyridinium Bis(Trifluoromethylsulfonyl)Imide. A Theoretical and Experimental Study Molecules doi: 10.3390/molecules24183382 Authors: Báez Navarro Fuenzalida Aguirre Arévalo Afonso García Ramírez Palenzuela In this work, we studied carbon paste electrodes (CPEs) with two kinds of binders: mineral oil or ionic liquids...
Tue Sep 17, 2019 03:00
Molecules, Vol. 24, Pages 3381: The Comprehensive Evaluation of Safflowers in Different Producing Areas by Combined Analysis of Color, Chemical Compounds, and Biological Activity Molecules doi: 10.3390/molecules24183381 Authors: Zong-Jin Pu Shi-Jun Yue Gui-Sheng Zhou Hui Yan Xu-Qin Shi Zhen-Hua Zhu Sheng-Liang Huang Guo-Ping Peng Yan-Yan Chen Ji-Qing Bai Xiao-Ping Wang Shu-Lan Su Yu-Ping Tang Jin-Ao Duan In the present study, a new strategy including...
Tue Sep 17, 2019 03:00
Molecules, Vol. 24, Pages 3383: Toxicity Prediction Method Based on Multi-Channel Convolutional Neural Network Molecules doi: 10.3390/molecules24183383 Authors: Yuan Wei Guan Jiang Wang Zhang Li Molecular toxicity prediction is one of the key studies in drug design. In this paper, a deep learning network based on a two-dimension grid of molecules is proposed to predict toxicity. At first, the van der Waals force and hydrogen bond were calculated according to...
Tue Sep 17, 2019 03:00
Molecules, Vol. 24, Pages 3380: Transcriptome and Metabolite Profiling Reveal Novel Insights into Volatile Heterosis in the Tea Plant (Camellia Sinensis) Molecules doi: 10.3390/molecules24183380 Authors: Yucheng Zheng Pengjie Wang Xuejin Chen Yun Sun Chuan Yue Naixing Ye Tea aroma is a key indicator for evaluating tea quality. Although notable success in tea aroma improvement has been achieved with heterosis breeding technology, the molecular basis underlying heterosis...
Tue Sep 17, 2019 03:00
Molecules, Vol. 24, Pages 3379: Mir-152 Regulates 3T3-L1 Preadipocyte Proliferation and Differentiation Molecules doi: 10.3390/molecules24183379 Authors: Yuan Fan Mailin Gan Ya Tan Lei Chen Linyuan Shen Lili Niu Yihui Liu Guoqing Tang Yanzhi Jiang Xuewei Li Shunhua Zhang Lin Bai Li Zhu Adipogenesis is a complex biological process and the main cause of obesity. Recently, microRNAs (miRNAs), a class of small endogenous non-coding RNAs, have been proven...
Tue Sep 17, 2019 03:00
Molecules, Vol. 24, Pages 3378: Effect of PLA/PBAT Antibacterial Film on Storage Quality of Passion Fruit during the Shelf-Life Molecules doi: 10.3390/molecules24183378 Authors: Rong Zhang Wenting Lan Jie Ding Saeed Ahmed Wen Qin Li He Yaowen Liu In this experiment, we studied the effect of poly(lactic acid)/poly(butylene adipate-co-terephthalate) (PLA/PBAT) blend films on the efficiency of passion fruit preservation at 20 °C. The weight loss, shrinkage index,...
Tue Sep 17, 2019 03:00
Molecules, Vol. 24, Pages 3377: Sensory Metabolite Profiling in a Date Pit Based Coffee Substitute and in Response to Roasting as Analyzed via Mass Spectrometry Based Metabolomics Molecules doi: 10.3390/molecules24183377 Authors: Mohamed A. Farag Asmaa M. Otify Aly M. El-Sayed Camilia G. Michel Shaimaa A. ElShebiney Anja Ehrlich Ludger A. Wessjohann Interest in developing coffee substitutes is on the rise, to minimizing its health side effects. In the Middle East, date...
Tue Sep 17, 2019 03:00
Molecules, Vol. 24, Pages 3374: Fabrication of Graphene/Molybdenum Disulfide Composites and Their Usage as Actuators for Electrochemical Sensors and Biosensors Molecules doi: 10.3390/molecules24183374 Authors: Jiri Kudr Vojtech Adam Ondrej Zitka From the rediscovery of graphene in 2004, the interest in layered graphene analogs has been exponentially growing through various fields of science. Due to their unique properties, novel two-dimensional family of materials and especially...
Tue Sep 17, 2019 03:00
Molecules, Vol. 24, Pages 3376: Anti-Inflammatory Properties of Bellevalia saviczii Root Extract and Its Isolated Homoisoflavonoid (Dracol) Are Mediated by Modification on Calcium Signaling Molecules doi: 10.3390/molecules24183376 Authors: Monica Savio Mohammed Farhad Ibrahim Chiara Scarlata Matteo Orgiu Giuseppe Accardo Abdullah Shakur Sardar Francesco Moccia Lucia Anna Stivala Gloria Brusotti Bellevalia saviczii is a medicinal plant used as anti-rheumatic and...
Tue Sep 17, 2019 03:00
Molecules, Vol. 24, Pages 3375: Screening 89 Pesticides in Fishery Drugs by Ultrahigh Performance Liquid Chromatography Tandem Quadrupole-Orbitrap Mass Spectrometer Molecules doi: 10.3390/molecules24183375 Authors: Shou-Ying Wang Cong Kong Qing-Ping Chen Hui-Juan Yu Multiclass screening of drugs with high resolution mass spectrometry is of great interest due to its high time-efficiency and excellent accuracy. A high-scale, fast screening method for pesticides in fishery drugs...
Tue Sep 17, 2019 03:00
MTI, Vol. 3, Pages 63: Can Skeuomorphic Design Provide a Better Online Banking User Experience for Older Adults? Multimodal Technologies and Interaction doi: 10.3390/mti3030063 Authors: Aaron Ellis Mark T. Marshall With the prevalence of digital technologies and internet connectivity, combined with the reduction in footfall on high streets, banks have taken steps to move most of their customer base online. This has left many older adults behind, trying to keep up with the changes...
Tue Sep 17, 2019 03:00
Nanomaterials, Vol. 9, Pages 1331: Mussel-Inspired Fabrication of SERS Swabs for Highly Sensitive and Conformal Rapid Detection of Thiram Bactericides Nanomaterials doi: 10.3390/nano9091331 Authors: Jun Liu Tiantian Si Lingzi Zhang Zhiliang Zhang As an important sort of dithiocarbamate bactericide, thiram has been widely used for fruits, vegetables and mature crops to control various fungal diseases; however, the thiram residues in the environment pose a serious threat to human...
Tue Sep 17, 2019 03:00
ncRNA, Vol. 5, Pages 46: The Growth-Arrest-Specific (GAS)-5 Long Non-Coding RNA: A Fascinating lncRNA Widely Expressed in Cancers Non-Coding RNA doi: 10.3390/ncrna5030046 Authors: Goustin Thepsuwan Kosir Lipovich Long non-coding RNA (lncRNA) genes encode non-messenger RNAs that lack open reading frames (ORFs) longer than 300 nucleotides, lack evolutionary conservation in their shorter ORFs, and do not belong to any classical non-coding RNA category. LncRNA genes equal, or...
Tue Sep 17, 2019 03:00
ncRNA, Vol. 5, Pages 45: meiRNA, A Polyvalent Player in Fission Yeast Meiosis Non-Coding RNA doi: 10.3390/ncrna5030045 Authors: Akira Yamashita A growing number of recent studies have revealed that non-coding RNAs play a wide variety of roles beyond expectation. A lot of non-coding RNAs have been shown to function by forming intracellular structures either in the nucleus or the cytoplasm. In the fission yeast Schizosaccharomyces pombe, a non-coding RNA termed meiRNA has been shown to...
Tue Sep 17, 2019 03:00
Nutrients, Vol. 11, Pages 2239: Free Amino Acid Content in Human Milk is Associated with Infant Gender and Weight Gain during the First Four Months of Lactation Nutrients doi: 10.3390/nu11092239 Authors: Baldeón Zertuche Flores Fornasini Background: There is a growing interest regarding the physiological role of free amino acids (FAA) present in human milk (HM). Recent studies show FAA in HM could be influenced by infants’ gender and could have an important role...
Tue Sep 17, 2019 03:00
Nutrients, Vol. 11, Pages 2238: Appetite-Suppressing and Satiety-Increasing Bioactive Phytochemicals: A Systematic Review Nutrients doi: 10.3390/nu11092238 Authors: Johann Stuby Isaac Gravestock Evelyn Wolfram Giuseppe Pichierri Johann Steurer Jakob M. Burgstaller The prevalence of obesity is increasing worldwide. Bioactive phytochemicals in food supplements are a trending approach to facilitate dieting and to improve patients’ adherence to reducing food and...
Tue Sep 17, 2019 03:00
Nutrients, Vol. 11, Pages 2237: The Effects of Dairy Intake on Insulin Resistance: A Systematic Review and Meta-Analysis of Randomized Clinical Trials Nutrients doi: 10.3390/nu11092237 Authors: Kristen M. Sochol Tanya S. Johns Rupinder S. Buttar Lovepreet Randhawa Edeline Sanchez Maya Gal Katherine Lestrade Massini Merzkani Matthew K. Abramowitz Yasmin Mossavar-Rahmani Michal L. Melamed The incidence of type 2 diabetes mellitus (DM) has increased in the...
Tue Sep 17, 2019 03:00
Nutrients, Vol. 11, Pages 2236: A Randomized Controlled Trial Evaluating the Relative Effectiveness of the Multiple Traffic Light and Nutri-Score Front of Package Nutrition Labels Nutrients doi: 10.3390/nu11092236 Authors: Eric A. Finkelstein Felicia Jia Ler Ang Brett Doble Wei Han Melvin Wong Rob M. van Dam The objective of this trial was to test two promising front-of-pack nutrition labels, 1) the United Kingdom’s Multiple Traffic Lights (MTL) label and 2) France’s...
Tue Sep 17, 2019 03:00
Pharmaceuticals, Vol. 12, Pages 139: Phosphonic Acid Analogues of Phenylglycine as Inhibitors of Aminopeptidases: Comparison of Porcine Aminopeptidase N, Bovine Leucine Aminopeptidase, Tomato Acidic Leucine Aminopeptidase and Aminopeptidase from Barley Seeds Pharmaceuticals doi: 10.3390/ph12030139 Authors: Weronika Wanat Michał Talma Małgorzata Pawełczak Paweł Kafarski The inhibitory activity of 14 racemic phosphonic acid analogs of phenylglycine, substituted in aromatic rings,...
Tue Sep 17, 2019 03:00
Pharmaceutics, Vol. 11, Pages 482: Pharmacokinetic Study of NADPH Oxidase Inhibitor Ewha-18278, a Pyrazole Derivative Pharmaceutics doi: 10.3390/pharmaceutics11090482 Authors: Seul Gee Lee Jaeok Lee Kyung Min Kim Kee-In Lee Yun Soo Bae Hwa Jeong Lee In a previous study, the specific NOX1/2/4 inhibitor Ewha-18278 was confirmed as a possible treatment for osteoporosis both in vitro and in vivo. Here, we investigated the pharmacokinetics (PK) of the compound by intravenous...
Tue Sep 17, 2019 03:00
Pharmaceutics, Vol. 11, Pages 481: Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors Pharmaceutics doi: 10.3390/pharmaceutics11090481 Authors: Babu V. Sajesh Ngoc H. On Refaat Omar Samaa Alrushaid Brian M. Kopec Wei-Guang Wang Han-Dong Sun Ryan Lillico Ted M. Lakowski Teruna J. Siahaan Neal M. Davies Pema-Tenzin Puno Magimairajan Issai Vanan Donald W. Miller The blood-brain...
Tue Sep 17, 2019 03:00
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