Antioxidants, Vol. 8, Pages 407: Nitric Oxide-Mediated Enhancement and Reversal of Resistance of Anticancer Therapies Antioxidants doi: 10.3390/antiox8090407 Authors: Emily Hays Benjamin Bonavida In the last decade, immune therapies against human cancers have emerged as a very effective therapeutic strategy in the treatment of various cancers, some of which are resistant to current therapies. Although the clinical responses achieved with many therapeutic strategies were significant...
Tue Sep 17, 2019 03:00
Antioxidants, Vol. 8, Pages 406: The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value Antioxidants doi: 10.3390/antiox8090406 Authors: Andrea Gomez-Zavaglia Miguel A. Prieto Lage Cecilia Jimenez-Lopez Juan C. Mejuto Jesus Simal-Gandara Two thirds of the world is covered by oceans, whose upper layer is inhabited by algae. This means that there is a large extension to obtain these photoautotrophic organisms. Algae have undergone...
Tue Sep 17, 2019 03:00
Antioxidants, Vol. 8, Pages 405: LC-ESI-QTOF/MS Characterisation of Phenolic Acids and Flavonoids in Polyphenol-Rich Fruits and Vegetables and Their Potential Antioxidant Activities Antioxidants doi: 10.3390/antiox8090405 Authors: Chunhe Gu Kate Howell Frank R. Dunshea Hafiz A. R. Suleria Polyphenols are naturally occurring compounds found largely in fruits and vegetables. The antioxidant properties of these polyphenols including total phenolic content (TPC), total flavonoid...
Tue Sep 17, 2019 03:00
Antioxidants, Vol. 8, Pages 404: S-Nitrosylation: An Emerging Paradigm of Redox Signaling Antioxidants doi: 10.3390/antiox8090404 Authors: Veani Fernando Xunzhen Zheng Yashna Walia Vandana Sharma Joshua Letson Saori Furuta Nitric oxide (NO) is a highly reactive molecule, generated through metabolism of L-arginine by NO synthase (NOS). Abnormal NO levels in mammalian cells are associated with multiple human diseases, including cancer. Recent studies have uncovered that...
Tue Sep 17, 2019 03:00
Atmosphere, Vol. 10, Pages 557: Air Quality Impacts of Smoke from Hazard Reduction Burns and Domestic Wood Heating in Western Sydney Atmosphere doi: 10.3390/atmos10090557 Authors: Maximilien Desservettaz Frances Phillips Travis Naylor Owen Price Stephanie Samson John Kirkwood Clare Paton-Walsh Air quality was measured in Auburn, a western suburb of Sydney, Australia, for approximately eighteen months during 2016 and 2017. A long open-path infrared spectrometer sampled...
Tue Sep 17, 2019 03:00
Atmosphere, Vol. 10, Pages 556: Brake Wear Particle Emissions of a Passenger Car Measured on a Chassis Dynamometer Atmosphere doi: 10.3390/atmos10090556 Authors: Marcel Mathissen Theodoros Grigoratos Tero Lahde Rainer Vogt Brake wear emissions with a special focus on particle number (PN) concentrations were investigated during a chassis dynamometer measurement campaign. A recently developed, well-characterized, measurement approach was applied to measure brake particles in a...
Tue Sep 17, 2019 03:00
Biomolecules, Vol. 9, Pages 498: Computationally Designed Peptides for Zika Virus Detection: An Incremental Construction Approach Biomolecules doi: 10.3390/biom9090498 Authors: Marcello Mascini Emre Dikici Marta Robles Mañueco Julio A. Perez-Erviti Sapna K. Deo Dario Compagnone Joseph Wang José M. Pingarrón Sylvia Daunert Herein, and in contrast to current production of anti-Zika virus antibodies, we propose a semi-combinatorial virtual strategy to select short...
Tue Sep 17, 2019 03:00
Biomolecules, Vol. 9, Pages 497: Protein Engineering of Multi-Modular Transcription Factor Alcohol Dehydrogenase Repressor 1 (Adr1p), a Tool for Dissecting In Vitro Transcription Activation Biomolecules doi: 10.3390/biom9090497 Authors: Buttinelli Panetta Bucci Frascaria Morea Miele Studying transcription machinery assembly in vitro is challenging because of long intrinsically disordered regions present within the multi-modular transcription factors. One example...
Tue Sep 17, 2019 03:00
Biomolecules, Vol. 9, Pages 496: Creatine as a Candidate to Prevent Statin Myopathy Biomolecules doi: 10.3390/biom9090496 Authors: Balestrino Adriano Statins prevent cardiovascular diseases, yet their use is limited by the muscle disturbances they cause. Rarely, statin-induced myopathy is autoimmune, but more commonly it is due to direct muscle toxicity. Available evidence suggests that statin-induced creatine deficiency might be a major cause of this toxicity, and that creatine...
Tue Sep 17, 2019 03:00
Biomolecules, Vol. 9, Pages 495: Unraveling Binding Mechanism of Alzheimer’s Drug Rivastigmine Tartrate with Human Transferrin: Molecular Docking and Multi-Spectroscopic Approach towards Neurodegenerative Diseases Biomolecules doi: 10.3390/biom9090495 Authors: Anas Shamsi Taj Mohammad Mohd Shahnawaz Khan Moyad Shahwan Fohad Mabood Husain Md. Tabish Rehman Md. Imtaiyaz Hassan Faizan Ahmad Asimul Islam Studying drug–protein interactions has gained significant...
Tue Sep 17, 2019 03:00
Biosensors, Vol. 9, Pages 109: Characterization of Binding of Magnetic Nanoparticles to Rolling Circle Amplification Products by Turn-On Magnetic Assay Biosensors doi: 10.3390/bios9030109 Authors: Sobhan Sepehri Björn Agnarsson Teresa Zardán Gómez de la Torre Justin F. Schneiderman Jakob Blomgren Aldo Jesorka Christer Johansson Mats Nilsson Jan Albert Maria Strømme Dag Winkler Alexei Kalaboukhov The specific binding of oligonucleotide-tagged 100 nm magnetic...
Tue Sep 17, 2019 03:00
Cancers, Vol. 11, Pages 1385: XIST-Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality Cancers doi: 10.3390/cancers11091385 Authors: Lobo Nunes Gillis Barros-Silva Miranda-Gonçalves Berg Cantante Guimarães Henrique Jerónimo Looijenga Background: The event of X chromosome inactivation induced by XIST, which is physiologically observed in females, is retained in testicular germ cell tumors (TGCTs),...
Tue Sep 17, 2019 03:00
Cancers, Vol. 11, Pages 1383: Encapsulated Carbenoxolone Reduces Lung Metastases Cancers doi: 10.3390/cancers11091383 Authors: Adi Karsch-Bluman Shimrit Avraham Miri Assayag Ouri Schwob Ofra Benny Carbenoxolone is an anti-inflammatory compound and a derivate of a natural substance from the licorice plant. We previously showed that carbenoxolone reduces the metastatic burden in the lungs of mice through its antagonistic effect on high mobility group box 1 (HMGB1). To further...
Tue Sep 17, 2019 03:00
Cancers, Vol. 11, Pages 1384: Molecular Mechanisms Underlying Yatein-Induced Cell-Cycle Arrest and Microtubule Destabilization in Human Lung Adenocarcinoma Cells Cancers doi: 10.3390/cancers11091384 Authors: Shang-Tse Ho Chi-Chen Lin Yu-Tang Tung Jyh-Horng Wu Yatein is an antitumor agent isolated from Calocedrus formosana Florin leaves extract. In our previous study, we found that yatein inhibited the growth of human lung adenocarcinoma A549 and CL1-5 cells by inducing intrinsic...
Tue Sep 17, 2019 03:00
Cancers, Vol. 11, Pages 1380: Age-Related Alterations in Immune Contexture Are Associated with Aggressiveness in Rhabdomyosarcoma Cancers doi: 10.3390/cancers11091380 Authors: Patrizia Gasparini Orazio Fortunato Loris De Cecco Michela Casanova Maria Federica Iannó Andrea Carenzo Giovanni Centonze Massimo Milione Paola Collini Mattia Boeri Matteo Dugo Chiara Gargiuli Mavis Mensah Miriam Segale Luca Bergamaschi Stefano Chiaravalli Maria Luisa Sensi...
Tue Sep 17, 2019 03:00
Cancers, Vol. 11, Pages 1381: BRAF Mutations Classes I, II, and III in NSCLC Patients Included in the SLLIP Trial: The Need for a New Pre-Clinical Treatment Rationale Cancers doi: 10.3390/cancers11091381 Authors: Jillian Wilhelmina Paulina Bracht Niki Karachaliou Trever Bivona Richard B. Lanman Iris Faull Rebecca J. Nagy Ana Drozdowskyj Jordi Berenguer Manuel Fernandez-Bruno Miguel Angel Molina-Vila Rafael Rosell BRAF V600 mutations have been found in 1–2%...
Tue Sep 17, 2019 03:00
Cancers, Vol. 11, Pages 1379: Observations on Solitary Versus Multiple Isolated Pancreatic Metastases of Renal Cell Carcinoma: Another Indication of a Seed and Soil Mechanism? Cancers doi: 10.3390/cancers11091379 Authors: Franz Sellner Isolated pancreas metastases are a rare type of metastasis of renal cell carcinoma, characterized by the presence of pancreatic metastases, while all other organs remain unaffected. In a previous study, we determined arguments from the literature which...
Tue Sep 17, 2019 03:00
Cancers, Vol. 11, Pages 1382: Radioiodine-Refractory Thyroid Cancer: Molecular Basis of Redifferentiation Therapies, Management, and Novel Therapies Cancers doi: 10.3390/cancers11091382 Authors: Mohamed Aashiq Deborah A. Silverman Shorook Na’ara Hideaki Takahashi Moran Amit Recurrent, metastatic disease represents the most frequent cause of death for patients with thyroid cancer, and radioactive iodine (RAI) remains a mainstay of therapy for these patients. Unfortunately,...
Tue Sep 17, 2019 03:00
Cells, Vol. 8, Pages 1098: How Cancer Exploits Ribosomal RNA Biogenesis: A Journey beyond the Boundaries of rRNA Transcription Cells doi: 10.3390/cells8091098 Authors: Gaviraghi Vivori Tonon The generation of new ribosomes is a coordinated process essential to sustain cell growth. As such, it is tightly regulated according to cell needs. As cancer cells require intense protein translation to ensure their enhanced growth rate, they exploit various mechanisms to boost ribosome...
Tue Sep 17, 2019 03:00
Cells, Vol. 8, Pages 1097: DNA Damage Changes Distribution Pattern and Levels of HP1 Protein Isoforms in the Nucleolus and Increases Phosphorylation of HP1β-Ser88 Cells doi: 10.3390/cells8091097 Authors: Legartová Lochmanová Zdráhal Kozubek Šponer Krepl Pokorná Bártová The family of heterochromatin protein 1 (HP1) isoforms is essential for chromatin packaging, regulation of gene expression, and repair of damaged DNA. Here we document that γ-radiation...
Tue Sep 17, 2019 03:00
Cells, Vol. 8, Pages 1095: Fatty Acid-Treated Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes Exhibit Adult Cardiomyocyte-Like Energy Metabolism Phenotypes Cells doi: 10.3390/cells8091095 Authors: Yuichi Horikoshi Yasheng Yan Maia Terashvili Clive Wells Hisako Horikoshi Satoshi Fujita Zeljko J. Bosnjak Xiaowen Bai Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (CMs) (iPSC-CMs) are a promising cell source for myocardial regeneration,...
Tue Sep 17, 2019 03:00
Cells, Vol. 8, Pages 1096: Reappraisal of Human HOG and MO3.13 Cell Lines as a Model to Study Oligodendrocyte Functioning Cells doi: 10.3390/cells8091096 Authors: Kim M. A. De Kleijn Wieteke A. Zuure Jolien Peijnenborg Josje M. Heuvelmans Gerard J. M. Martens Myelination of neuronal axons is essential for proper brain functioning and requires mature myelinating oligodendrocytes (myOLs). The human OL cell lines HOG and MO3.13 have been widely used as in vitro models to study...
Tue Sep 17, 2019 03:00
Children, Vol. 6, Pages 104: Pneumomediastinum Mimicking Congenital Pulmonary Airway Malformation Children doi: 10.3390/children6090104 Authors: Kylat Pneumomediastinum is the collection of free air in the mediastinum. Its incidence is higher in preterm infants and those on positive airway pressure support or on mechanical ventilation. But it has decreased dramatically after the introduction of surfactant and synchronized, non-invasive mechanical ventilation. Underlying cystic lesions...
Tue Sep 17, 2019 03:00
Climate, Vol. 7, Pages 112: The Origin and Propagation of the Antarctic Centennial Oscillation Climate doi: 10.3390/cli7090112 Authors: W. Jackson Davis Peter J. Taylor W. Barton Davis The Antarctic Centennial Oscillation (ACO) is a paleoclimate temperature cycle that originates in the Southern Hemisphere, is the presumptive evolutionary precursor of the contemporary Antarctic Oscillation (AAO), and teleconnects to the Northern Hemisphere to influence global temperature. In this...
Tue Sep 17, 2019 03:00
Diversity, Vol. 11, Pages 170: First Survey of Heterobranch Sea Slugs (Mollusca, Gastropoda) from the Island Sangihe, North Sulawesi, Indonesia Diversity doi: 10.3390/d11090170 Authors: Nani Undap Adelfia Papu Dorothee Schillo Frans Gruber Ijong Fontje Kaligis Meita Lepar Cora Hertzer Nils Böhringer Gabriele M. König Till F. Schäberle Heike Wägele Indonesia is famous for its underwater biodiversity, which attracts many tourists, especially divers. This is...
Tue Sep 17, 2019 03:00
Diversity, Vol. 11, Pages 168: Role of Reef-Building, Ecosystem Engineering Polychaetes in Shallow Water Ecosystems Diversity doi: 10.3390/d11090168 Authors: Martín Bruschetti Although the effect of ecosystem engineers in structuring communities is common in several systems, it is seldom as evident as in shallow marine soft-bottoms. These systems lack abiotic three-dimensional structures but host biogenic structures that play critical roles in controlling abiotic conditions and resources....
Tue Sep 17, 2019 03:00
Diversity, Vol. 11, Pages 169: Mitochondrial Genome Diversity in Collembola: Phylogeny, Dating and Gene Order Diversity doi: 10.3390/d11090169 Authors: Chiara Leo Antonio Carapelli Francesco Cicconardi Francesco Frati Francesco Nardi Collembola (springtails) are an early diverging class of apterygotes, and mark the first substantial radiation of hexapods on land. Despite extensive work, the relationships between major collembolan lineages are still debated and, apart from...
Tue Sep 17, 2019 03:00
Fermentation, Vol. 5, Pages 82: Anhydrobiosis in Yeasts: Changes in Mitochondrial Membranes Improve the Resistance of Saccharomyces cerevisiae Cells to Dehydration–Rehydration Fermentation doi: 10.3390/fermentation5030082 Authors: Galina Khroustalyova Alexander Rapoport Anhydrobiosis is a unique state of live organisms in which their metabolism is temporary reversibly suspended as the result of strong dehydration of their cells. This state is widely used currently during large-capacity...
Tue Sep 17, 2019 03:00
Foods, Vol. 8, Pages 420: Prevalence, Virulence, and Antimicrobial Resistance of Campylobacter spp. in Raw Milk, Beef, and Pork Meat in Northern Poland Foods doi: 10.3390/foods8090420 Authors: Małgorzata Andrzejewska Bernadeta Szczepańska Dorota Śpica Jacek J. Klawe The purpose of this study was to determine whether raw milk, unpasteurized dairy products, pork, and beef available for sale in the Kujawsko-Pomorskie and Wielkopolska regions in Poland are contaminated with Campylobacter...
Tue Sep 17, 2019 03:00
Healthcare, Vol. 7, Pages 108: Immunotherapy for Uterine Cervical Cancer Healthcare doi: 10.3390/healthcare7030108 Authors: Masahiro Kagabu Takayuki Nagasawa Daisuke Fukagawa Hidetoshi Tomabechi Saiya Sato Tadahiro Shoji Tsukasa Baba Cervical cancer is a malignant neoplastic disease that is the fourth most commonly occurring cancer in women worldwide. Since the introduction of angiogenesis inhibitors, treatments for recurrent and advanced cervical cancers have improved...
Tue Sep 17, 2019 03:00
Heritage, Vol. 2, Pages 2652-2664: Mineralogical Characterization and Firing Temperature Delineation on Minoan Pottery, Focusing on the Application of Micro-Raman Spectroscopy Heritage doi: 10.3390/heritage2030163 Authors: E. Grammatikakis Kyriakidis D. Demadis Cabeza Diaz Leon-Reina Ceramic objects in whole or in fragments usually account for the majority of findings in an archaeological excavation. Thus, through examination of the values these items bear, it is possible...
Tue Sep 17, 2019 03:00
IJERPH, Vol. 16, Pages 3462: Factors Correlated with Smoking Cessation Success in Older Adults: A Retrospective Cohort Study in Taiwan International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16183462 Authors: Chih-Po Chang Wei-Hsin Huang Ching-Hui You Lee-Ching Hwang I-Jung Lu Hsin-Lung Chan Smoking cessation in the elderly is very important. This study aims to explore the success rate of smoking cessation in the elderly and the factors that...
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IJERPH, Vol. 16, Pages 3465: Generalized Violence as a Threat to Health and Well-Being: A Qualitative Study of Youth Living in Urban Settings in Central America’s “Northern Triangle” International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16183465 Authors: Maria De Jesus Carissa Hernandes El Salvador, Guatemala, and Honduras rank among the top 10 countries experiencing violence in the world, despite not being at war. Although there is abundant literature...
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IJERPH, Vol. 16, Pages 3464: Association between the Occurrence of Primary Hypothyroidism and the Exposure of the Population Near to Industrial Pollutants in São Paulo State, Brazil International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16183464 Authors: Maria Angela Zaccarelli-Marino Rudá Alessi Thalles Zaccarelli Balderi Marco Antonio Garcia Martins Background: Environmental agents interfere with thyroid function at multiple levels. This study...
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IJERPH, Vol. 16, Pages 3463: Exploring the Impact of the Rational Antibiotic Use System on Hospital Performance: The Direct Effect and the Spillover Effect International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16183463 Authors: Shanshan Guo Wenchao Du Shuqing Chen Xitong Guo Xiaofeng Ju Irrational antibiotic usage not only causes an increase in antibiotic-borne diseases, but also inflicts pain on patients, as a result of inappropriate treatment....
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IJERPH, Vol. 16, Pages 3461: Trends in Diabetes Prevalence, Awareness, Treatment and Control in Yangon Region, Myanmar, Between 2004 and 2014, Two Cross-Sectional Studies International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16183461 Authors: Wai Phyo Aung Espen Bjertness Aung Soe Htet Hein Stigum Marte Karoline Råberg Kjøllesdal Myanmar is currently facing the burden of non-communicable diseases due to changes in lifestyle and dietary patterns...
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IJERPH, Vol. 16, Pages 3460: The Effect of Improving Cycleway Environment on the Recreational Benefits of Bicycle Tourism International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16183460 Authors: Yeh Lin Hsiao Huang Bicycle tourism is one of the popular physical activities for sport tourists. Since the physical environment may affect bicycling behavior, it becomes an important determinant for cyclists to choose a cycleway. Exploratory factor...
Tue Sep 17, 2019 03:00
IJERPH, Vol. 16, Pages 3459: Relationship between Air Pollution and Urban Forms: Evidence from Prefecture-Level Cities of the Yangtze River Basin International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16183459 Authors: He Liu He Zhou Urban forms, such as size, shape, density, compactness, and fragmentation, are associated with local air pollution concentrations. However, empirical analyses on how urban form improves or degrades urban air quality...
Tue Sep 17, 2019 03:00
IJERPH, Vol. 16, Pages 3457: The Association between Frailty Indicators and Blood-Based Biomarkers in Early-Old Community Dwellers of Thailand International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16183457 Authors: Warathit Semmarath Mathuramat Seesen Supachai Yodkeeree Ratana Sapbamrer Pisittawoot Ayood Rungnapa Malasao Penprapa Siviroj Pornngarm Limtrakul (Dejkriengkraikul) Thailand has officially reached the status of an “aged...
Tue Sep 17, 2019 03:00
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