Voice

Yong Tae Hong*,‡, Seok Tae Lim†, Ki Hwan Hong*,‡,low asterisklow asterisk,'Correspondence information about the author Ki Hwan HongEmail the author Ki Hwan Hong DOI: https://doi.org/10.1016/j.jvoice.2019.08.021 hideArticle Info Publication History Published online:September 28, 2019 Accepted:August 21, 2019 Abstract Full Text Images References Supplemental Materials Summary Background and Objectives The larynx is an end-organ target for hormones, and thyroid hormone may act on the larynx. We objectively compared and analyzed the phonetic characteristics of patients who underwent total thyroidectomy before and after radioiodine therapy (RIT) according to administration of recombinant human TSH (rh-TSH). Subjects and Methods Ninety-one patients who had undergone a total thyroidectomy participated (50 patients without rh-TSH, 41 patients with rh-TSH). Voice samples were obtained postoperatively (Post-OP), before high-dose RIT (Pre-RIT), and after high-dose RIT (Post-RIT). Frequency-, perturbation-, and noise-related parameters were evaluated for acoustic analysis, and the voice handicap index (VHI) was used for the subjective evaluation. Results Frequency-related parameters decreased significantly in patients without rh-TSH administration, but not changed at three periods in patients with rh-TSH administration. Pitch perturbation parameters were not changed at each period in two groups, but amplitude perturbation parameters were changed significantly in two groups. The functional scores of the VHI increased significantly at Pre-RIT in two groups and physical scores increased in patients without rh-TSH at Pre-RIT. Conclusion The hypothyroidism after total thyroidectomy affects phonation significantly. Our results suggest that rh-TSH administration during RIT resulted in improving voice results during RIT in the patients with total thyroidectomy. Key Words: Thyroidectomy, Hypothyroidism voice radioisotope, Recombinant human TSH

Voice Outcome of Total Thyroidectomy in Comparison With Administration of Recombinant Human TSH The larynx is an end-organ target for hormones, and thyroid hormone may act on the larynx. We objectively compared and analyzed the phonetic characteristics of patients who underwent total thyroidectomy before and after radioiodine therapy (RIT) according to administration of recombinant human TSH (rh-TSH).

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Vocal Fatigue in Prospective Vocal Professionals The goals of the study were to (a) examine vocal fatigue in speech-language pathology students through subjective and objective measures following a novel 30-minute vocal loading task (VLT) and (b) evaluate the effects of psychosocial factors on vocal fatigue.