MYC-rearrangement within 2 years after diagnosis may affect the prognosis of patients with diffuse large B-cell lymphoma. (Source: CancerNetwork)
4h
Investigators assessed effects of TIB on cell number, migration, invasion, estrogen, and progesterone receptor activity and content. (Source: CancerNetwork)
4h
The FDA approved Cologuard, a stool-based, at-home colorectal cancer screening for adults aged 45 to 49 years. (Source: CancerNetwork)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
4h
Administration of antibiotics prior to immune checkpoint inhibitor therapy may reduce response to treatment and worsen survival outcomes in patients with cancer. (Source: CancerNetwork)
4h
Insomnia Severity Index scores improved for many cancer survivors with single sleep education session (Source: The Doctors Lounge - Psychiatry)
6h
By Sarah WolvertonWALLINGFORD, CT, US, Sep 24 2019 (IPS) Last year, the United States introduced a new asbestos rule that was received both positively and negatively and Canada banned the mineral altogether. Countries like the U.K. and Australia continue to struggle with the health implications of historic asbestos use, despite both having bans for several years. In contrast, nations like Russia and Vietnam continue to manufacture and use the mineral frequently. Asbestos is a substance that was...
11h
A teaching hospital has redesigned part of its cancer service after being flagged as an outlier in two national clinical audits. (Source: HSJ)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
11h
[New Times] The City of Kigali is undertaking an assessment of the most demanding needs for cancer patients in Kigali. (Source: AllAfrica News: Health and Medicine)
11h
Less weight gain and lower incidence of obesity among people who ate more nuts of any type, despite their high energy density Related items fromOnMedica Should we recognise obesity as a disease? Sugary drinks linked to risk of overall and breast cancer Scotland reveals target of halving child obesity by 2030 WHO dietary fat guidance fails to consider crucial evidence Taxing sugary foods would cut prevalence of obesity (Source: OnMedica Latest News)
11h
CAMBRIDGE, England and NEW YORK, Sept. 24, 2019 -- (Healthcare Sales & Marketing Network) -- Artios Pharma Limited (Artios), a leading DNA Damage Response (DDR) company developing a broad pipeline of innovative treatments for cancer, today announces the a... Biopharmaceuticals, Personnel Artios Pharma, DNA Damage Response (Source: HSMN NewsFeed)
13h
Contrast developer Guerbet and IBM Watson Health have signed an agreement to...Read more on AuntMinnie.comRelated Reading: Guerbet revenues slow in 2nd quarter Guerbet wins group purchasing agreement from Premier IBM launches Imaging Patient Synopsis Guerbet opens manufacturing site for Lipiodol IBM inks AI deals with Vanderbilt, Brigham and Women's VA and IBM Watson Health extend AI partnership (Source: AuntMinnie.com Headlines)MedWorm Message: If you are looking to buy something in the January...
13h
Young women at high risk of breast cancer due to a family or personal history...Read more on AuntMinnie.comRelated Reading: Women under 40 benefit from mammography, too Fewer high-risk women get mammography after USPSTF change DBT improves breast cancer screening in young women SABCS: Biannual breast MRI best for young women at high risk Screening breast MRI alone OK for high-risk women (Source: AuntMinnie.com Headlines)
13h
(CNN) — Torrent Pharmaceuticals Ltd. has expanded its voluntary recall of two blood pressure medications after trace amounts of a potentially cancer-causing impurity were found during testing. The recall affects Losartan Potassium Tablets USP and Losartan Potassium/hydrochlorothiazide tablets. Tests of some of those medications revealed amounts of N-methylnitrosobutyric acid (NMBA) that were above the US Food and Drug Administration’s daily acceptable levels. This recall is related to the valsartan...
15h
Experts say that no country's system is perfect, but there is much benefit to taking a worldwide view of cancer care.Medscape Oncology (Source: Medscape Today Headlines)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
15h
Severe lymphopenia following chemoradiotherapy compromises outcomes for patients with esophageal cancer, again underscoring the importance of the immune system in cancer control.Medscape Medical News (Source: Medscape Medical News Headlines)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
15h
I wanted to relish being spared the toxicity and side effects of chemo, but if it could help me potentially live longer, spend more time with my kids, shouldn ’t I do it anyway? (Source: NYT Health)
15h
A new report from the Mayo Clinic in Jacksonville, Florida, has found that more than six percent of breast cancer cases can be attributed to alcohol, which is a carcinogen. (Source: the Mail online | Health)
15h
(Natural News) New research published in the open-access journal Heliyon reveals that “drinking water” from the tap isn’t all that drinkable after all, seeing as how it often contains carcinogenic chemicals that increase cancer risk in people exposed to it. Over the course of a lifetime, warns the Environmental Working Group (EWG), the study’s author,... (Source: NaturalNews.com)
15h
Guerbet has landed a second co-development agreement with IBM Watson Health. This time around, the two companies will develop an artificial intelligence tool to help clinicians detect, segment, characterize, and monitor prostate cancer. âThe main diagnostic challenge with prostate cancer lies in identifying cancers requiring rapid treatment and those requiring only active surveillance while avoiding unnecessary biopsies," said David Gruen, MD, chief medical officer of imaging at IBM Watson Health....
15h
Carcinogens in tap water could be responsible for more than 100,000 cases of cancer in the United States according to a recent cumulative risk analysis. (Source: Health News from Medical News Today)
15h
(Source: eMedicineHealth.com)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
15h
Title: Can Aspirin Help Tackle Some Cancers?Category: Health NewsCreated: 9/23/2019 12:00:00 AMLast Editorial Review: 9/23/2019 12:00:00 AM (Source: MedicineNet Cancer General)
19h
A new study looks into whether disease stage at diagnosis affects the occureance and location of a second primary malignancy in DLBCL. (Source: CancerNetwork)
19h
Researchers examined whether cancer or treatment type impacted the symptom burden of survivors of cancer. (Source: CancerNetwork)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
19h
Abstract Youth substance use remains a significant public health issue. Although there are numerous evidence-based substance use preventive interventions, room for program improvement remains. Mindfulness practice, due to its feasibility of implementation, capacity to promote neuro-networks associated with delayed substance use initiation and progression to substance use disorders, and efficacy in promoting protective and reducing risk factors associated with substance use, may...
32m
Factor X deficiency is a rare bleeding disorder that varies in the severity of its clinical manifestations. The symptoms of this disorder can occur at any age, although most severe cases appear in childhood. The rarity of this condition has not allowed for the establishment of evidence‐based management guidelines, and thus, individuals afflicted with factor X deficiency are treated based on limited literature and the opinions of clinicians with extensive experience. In this case report, we discuss...
34m
Aiming at the complex nonlinear dynamic problem of cutting hard rock with diamond sawblades, the process of hard rock cutting with a diamond sawblade was studied based on ANSYS/LS-DYNA. A numerical simulation model of a diamond sawblade cutting hard rock with different rotation speeds, feed speeds, and cutting depths was established to study the effects of the cutting parameters on the cutting force and specific cutting energy consumption and on the damage to the rock. The numerical simulation results...
2h
Purpose. The aim of this retrospective cohort study was to evaluate intraocular pressure (IOP) changes during femtosecond laser-assisted cataract surgery (FLACS) using two different patient interface systems. Methods. 116 eyes of 116 patients scheduled for cataract surgery were divided into 2 groups: group 1 (61 eyes) and group 2 (55 eyes) underwent FLACS using Catalys Laser with fluid interface (liquid optics interface, LOI) and LenSx Laser with curved interface and soft contact lens (SoftFit),...
3h
Objectives. The aim of this study was to assess the performance of a previously published algorithm for first-trimester prediction of spontaneous preterm birth (PTB) in a cohort of Brazilian women. Methods. This was a retrospective cohort study of women undergoing routine antenatal care. Maternal characteristics and medical history were obtained. The data were inserted in the Fetal Medicine Foundation (FMF) online calculator to estimate the individual risk of PTB. Univariate and multivariate logistic...
5h
Understanding the effects of root temperature on plant growth and key food components of horticultural crops under greenhouse conditions is important. Here, we assess the impact of root cooling on plant growth and fruit quality of two cocktail tomato cultivars (Lycopersicon esculentum cv “Amoroso” and cv “Delioso”) during the winter of 2017-2018 and the summer of 2018. Plants were grown hydroponically on rockwool under different root temperatures (16–27°C and 10°C) from the 2nd inflorescence to harvest...
5h
The coordinated development of urban public infrastructure system and urban economic, social, and environmental system is an important goal for the integrated management and sustainable development of urban public infrastructure system. This paper constructs a research model of the degree of coupling coordination between urban public infrastructure system and urban economic, social, and environmental system using the analytic network process (ANP), the analytic hierarchy process (AHP), a combination...
5h
Only very few failure data can be obtained for the time censored test of high-reliability and long-life products. For very few failure data, the current methods fail to obtain both the point estimation and confidence interval of reliability parameters. If the point estimation and confidence interval of reliability parameters are obtained based on different methods, the results tend to be unreliable. In this study, based on the existing research, a Bayesian reliability evaluation method for very few...
5h
Background. Chinese herbal medicine (CHM) with reported hepatotoxicity is identified, in which Polygoni Multiflori Radix (HSW) attracts most attention. According to the Traditional Chinese Medicine (TCM) theory, processing is believed to be able to reduce the toxicity of HSW, but in publications, both processed and unprocessed HSW are reported to cause liver injury. Methods. This article reviews the case reports and experimental researches involving liver damage associated with HSW from the following...
5h
We report the case of a 45-year-old female who presented with acute left abdominal pain and subsequently developed a left partial Brown-Séquard syndrome. Spinal fluid, inflammatory and prothrombotic tests were unremarkable. Magnetic resonance showed a left intraforaminal disc prolapse at the T9–T10 level and a hyperintense lesion on T2-weighted images in the left postero-lateral cord at the T8–T9 level with restricted diffusion on DWI imaging. A diagnosis of spinal cord infarction due to compromise...
5h
Sedation during medical procedures poses a risk to any patient, and the use of specific anesthetic agents should be carefully considered to avoid adverse outcomes. We report on a patient with propofol infusion syndrome diagnosed during the post-operative period of a renal transplant. A 58-year-old female on chronic hemodialysis due to end stage kidney disease secondary to microscopic polyangiitis underwent kidney transplant from a deceased donor. Anesthetic induction was performed with fentanyl,...
5h
Inverse analysis is necessary for concrete dams in normal operation to overcome the discrepancy between the true mechanical parameters and test results. In view of the uncertain characteristics of concrete dams, a stochastic inverse model is proposed in this study to solve the undetermined mechanical parameters with sequential and spatial randomness using measured displacement data and Bayesian back analysis theory. An inversion method for the mechanical parameters of concrete dams is proposed. Fast...
5h
Objectives. The importance of preventive medicine in an aging society is increasing. Locomotive syndrome (LS) is attracting increasing attention. Recently, advances in bioelectrical impedance analysis (BIA) devices have made it possible to automatically measure waist circumference (WC). Nevertheless, there have been no reports evaluating the agreement or interchangeability between WC measured manually and using BIA. Therefore, we aimed to perform these analyses in the context of health checkups and...
5h
The main objective of this research was to evaluate the efficacy of intermittent hypoxic training (IHT) on aiming performance and aerobic capacity in biathletes. Fourteen male biathletes were randomly divided into a hypoxia group (H) (n = 7), which trained three times per week in a normobaric hypoxic environment (FiO2 = 16.5%, 2000 m a.s.l.) with lactate threshold intensity (LT) determined in hypoxia, and a control group (C) (n = 7), which exercised under normoxic conditions with LT intensity determined...
5h
Globe artichoke is an intriguing source of indigestible sugar polymers such as inulin-type fructans. In this study, the effect of ultrasound in combination with ethanol precipitation to enhance the extraction of long chain fructans from artichoke wastes has been evaluated. The inulin-type fructans content both from bracts and stems was measured using an enzymatic fructanase-based assay, while its average degree of polymerization (DP) was determined by HPLC-RID analysis. Results show that this method...
5h
Bacteria in biofilms are encased in an extracellular polymeric matrix that limits exposure of microbial cells to lethal doses of antimicrobial agents, leading to resistance. In Pseudomonas aeruginosa, biofilm formation is regulated by cell-to-cell communication, called quorum sensing. Quorum sensing facilitates a variety of bacterial physiological functions such as swarming motility and protease, pyoverdine, and pyocyanin productions. Peptide mix from the marine mollusc, Olivancillaria hiatula, has...
16h
This study aimed at investigating the effect of occupational health and safety (OHS) on employee’s turnover intention (TI) with the mediating effect of organizational commitment (OC) in the Ghanaian power industry. Methods. With stratified sampling technique, 350 participants were selected to participate in the study with standardized quantitative questionnaires to measure the variables involved in the study and SmartPLS 3-structural equation modeling technique to analyze the data. Results. The results...
16h
This paper proposes a unified system framework based on linear frequency modulation (LFM) and orthogonal frequency-division multiplexing (OFDM) as a solution for resource sharing, especially sharing space and hardware. The proposed OFDM-LFM framework can not only transmit data flow by OFDM but also make it possible to extract features from the signal by LFM. Further, the signal features are used to construct a pseudospectrum related to the target speed and distance, thereby estimating the speed and...
17h
In this work, the concept of a multipurpose mission that can explore both the Moon and Mars with a single launch is proposed, and potential launch opportunities are analyzed to establish an early-phase trajectory concept. The proposed mission applies the concept of a piggyback ride to a small-sized lunar probe, i.e., the daughtership, of the main Mars orbiter, i.e., the mothership. For the trajectory design, the Earth-Moon-Mars gravity assist (EMMGA) trajectory is adopted for the mothership to reach...
17h
Microstructural fracture behavior of a ceramic matrix composite (CMC) with nonuniformly distributed fibers is studied in the presentation. A comprehensive numerical analysis package to study the effect of nonuniform fiber dimensions and locations on the microstructural fracture behavior is developed. The package starts with an optimization algorithm for generating representative volume element (RVE) models that are statistically equivalent to experimental measurements. Experimentally measured statistical...
17h
This paper presents a test and numerical investigation into the monotonic behavior of three different complex steel trusses to concrete-filled tubular (CFT) column joints. Based on an engineering structure, 1 : 4 reduced-scale specimens are manufactured and the three-dimensional subassembly testing system is designed to apply the monotonic load. Test phenomena and load-stress curves show that all three types of joints have a considerable load-carrying capacity and joint rigidity. Finite element (FE)...
18h
The study investigated the effect of structural conditions of milk processing facilities and food safety systems on E. coli and coliform presence in buttermilk. Milk records collected by Dairy Services Zimbabwe (DSZ) from large-scale dairy milk processors () and small-scale farms () were analysed. Binomial logistic regression was used to estimate the likelihood of E. coli or coliforms being present in cultured buttermilk as a function of the hygiene level and structural adequacy of the processors....
19h
The electric network frequency (ENF) has a statistical uniqueness according to time and location. The ENF signal is always slightly fluctuating for the load balance of the power grid around the fundamental frequency. The ENF signals can be obtained from the power line using a frequency disturbance recorder (FDR). The ENF signal can also be extracted from video files or audio files because the ENF signal is also saved due to the influence of the electromagnetic field when video files or audio files...
19h
Melanoidin is one of the most important ingredients in black garlic due to the high nutritional values and biological functions. High hydrostatic pressures from 200 to 500 MPa were employed to extract the melanoidins from black garlic for improving the extraction efficiency and enhancing the activities. The results indicated that total phenolics, flavonoids, and sugar yields were all increased when pressure was applied and the antioxidant and overall reducing power was maximized. The bioactive properties...
20h
Microbial contamination is the cause of extensive economic loss in the food sector. Previously, the wide-range antimicrobial capacity of inhibitory substances secreted by the Lactobacillus plantarum UTNCys5-4 strain was demonstrated in vitro; however, its mechanism of action in the food matrix remains unclear. This study was aimed to evaluate the effect of antimicrobials produced by the Cys5-4 strain in raw meat applied as pure cell cultures, cell-free supernatant (CFS), and partially purified peptides....
20h
circRNAs are involved in diabetes mellitus pathogenesis. Electroacupuncture (EA) is an effective therapeutic strategy for diabetes mellitus. However, whether the mechanism of action of EA on diabetes mellitus is related to altered circRNAs is unclear. The aim of this study was to reveal the effect of EA on circRNA expression in plasma exosomes and the underlying signaling pathway in mice with type 2 diabetes mellitus (T2DM). In total, 10 mice were randomly categorized into a normal group and 20 mice...
20h
Background. The syndrome of drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare, yet potentially fatal hypersensitivity reaction, most commonly associated with anticonvulsants, sulfonamides, and allopurinol. The reaction commonly manifests as a febrile skin eruption with lymphadenopathy and malaise between two and eight weeks following drug exposure. Internal organ involvement occurs in close to 90 percent of patients, and multiple organs may be involved in approximately half...
20h
Background. Stigma related to mental illness can be an obstacle affecting the quality of life of people with mental illness. Although mental illness in the workplace is a public problem globally, few studies have investigated the effect of stigma on job-related problems such as burnout. Aim. This study aimed to clarify the association between mental-illness-related stigma and burnout among nonprofessional occupational mental health staff. Methods. In this cross-sectional study, nonprofessional occupational...
20h
Cyclooxygenase-2 (COX-2) is involved in the inflammatory response, and its recurrent overexpression in cancers as well as in neurodegenerative disorders has made it an important target for therapy. For this reason, noninvasive imaging of COX-2 expression may represent an important diagnostic tool. In this work, a COX-2 inhibitor analogue, VA426 [1-(4-fluorophenyl)-3-(2-methoxyethyl)-2-methyl-5-(4-(methylsulfonil)phenyl)-1H-pyrrole], was synthesized and radiolabelled with the 11C radioisotope. The...
21h
Purpose. Accumulating studies comparing the efficacy and safety of trabeculectomy and EX-PRESS implantation in open-angle glaucoma (OAG) report inconsistent findings. Thus, we conducted the updated meta-analysis to clarify the issue. Methods. Randomized controlled trials (RCTs) were selected through search of databases PubMed, Web of Science, Embase, and the Cochrane Library from their inception up until November 2018. The pooled mean difference (MD) for intraocular pressure reduction (IOPR) and...
21h
We investigated the role of miR-181a in diffuse large B-cell lymphoma (DLBCL) and its potential target genes. miR-181a levels were lower in activated B-cell- (ABC-) like DLBCL cells than that in germinal center B-cell- (GCB-) like DLBCL cells. Overexpression of miR-181a in ABC-like DLBCL cell lines (OCI-LY10 and U2932) resulted in G0/G1 cell cycle arrest, increased apoptosis, and decreased invasiveness. miRNA target prediction programs (miRanda, TargetScan, and miRDB) identified caspase recruitment...
21h
Gastric cancer (GC) is one of the most important malignancies worldwide because of its high incidence and mortality. The very low survival rates are mainly related to late diagnosis and limited treatment options. GC is the final clinical outcome of a stepwise process that starts with a chronic and sustained inflammatory reaction mounted in response to Helicobacter pylori infection. The bacterium modulates innate and adaptive immunity presumably as part of the strategies to survive, which favors the...
21h
In this study, an aluminum-containing charge was exploded in an enclosed simulation cabin to explore the characteristics of two types of damaging pressure loads formed by internal explosions: the first incident shock wave and the quasistatic pressure. A high-frequency piezoelectric sensor was used to measure the first incident shock wave and a low-frequency piezoresistive sensor was used to measure the quasistatic pressure. After obtaining effective experimental data, the experimental results were...
21h
Given the lack of research on the schoolchildren exposure to PM2.5-bound PHAs in northeast China, we investigated the effects of exposure to ambient benzo[b]fluoranthene (BbFA) and dibenz[a,h]anthracene (DahA) bound to PM2.5 on pulmonary ventilation dysfunction (PVD) and small airway dysfunction (SAD). PM2.5 samples at two schools (A and B) were collected, and the concentrations of PM2.5-bound 4–6-ring PAHs were analyzed. PVD and SAD were evaluated by pulmonary function tests in 306 students while...
21h
Sorghum (Sorghum bicolor (L.) Moench) is one of the most important cereals in the Northeast China. The physicochemical, pasting, texture, and cooking properties of 21 sorghum varieties were determined, which were mainly cultivated in Northeast China. Then, the evaluation of edible quality of sorghum was based on principal component analysis and fitted with the score of sensory evaluation. Five principal components (PCs) with a cumulative contribution rate of 86.19% could be picked out to describe...
22h
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