Antibiotics, Vol. 8, Pages 164: Gut Bacteria of Water Monitor Lizard (Varanus salvator) Are a Potential Source of Antibacterial Compound(s) Antibiotics doi: 10.3390/antibiotics8040164 Authors: Akbar Siddiqui Sagathevan Iqbal Khan For the past few decades, there has been limited progress in the development of novel antibacterials. Previously, we postulated that the gut microbiota of animals residing in polluted environments are a forthcoming supply of antibacterials....
Tue Sep 24, 2019 03:00
Antibiotics, Vol. 8, Pages 163: Countering Gram-Negative Antibiotic Resistance: Recent Progress in Disrupting the Outer Membrane with Novel Therapeutics Antibiotics doi: 10.3390/antibiotics8040163 Authors: Kelly M. Lehman Marcin Grabowicz Gram-negative bacteria shield themselves from antibiotics by producing an outer membrane (OM) that forms a formidable permeability barrier. Multidrug resistance among these organisms is a particularly acute problem that is exacerbated by the OM....
Tue Sep 24, 2019 03:00
Antioxidants, Vol. 8, Pages 426: The Odyssey of Bioactive Compounds in Avocado (Persea americana) and Their Health Benefits Antioxidants doi: 10.3390/antiox8100426 Authors: Deep Jyoti Bhuyan Muhammad A. Alsherbiny Saumya Perera Mitchell Low Amrita Basu Okram Abemsana Devi Mridula Saikia Barooah Chun Guang Li Konstantinos Papoutsis Persea americana, commonly known as avocado, has recently gained substantial popularity and is often marketed as a “superfood”...
Tue Sep 24, 2019 03:00
Arts, Vol. 8, Pages 124: Eerie Systems and Saudade for a Lost Nature Arts doi: 10.3390/arts8040124 Authors: Paul Goodfellow This paper considers Art’s engagement with the socio-ecological systems in operation in the world. Drawing from both environmental and art history, this paper employs the Deleuzean concept of the fold to suggest three overlapping periods of ecological-systems awareness over the past sixty years. This paper demonstrates how we have shifted our attention...
Tue Sep 24, 2019 03:00
Atmosphere, Vol. 10, Pages 576: Empirical Model of Thermal Comfort for Medium-Sized Cities in Subtropical Climate Atmosphere doi: 10.3390/atmos10100576 Authors: João Paulo Assis Gobo Marlon Resende Faria Emerson Galvani Margarete Cristiane de Costa Trindade Amorim Maria Cristina Celuppi Cássio Arthur Wollmann The present study sought to elaborate an empirical model of thermal comfort for medium-sized cities in subtropical climate, based on a cross-sectional survey in the...
Tue Sep 24, 2019 03:00
Atmosphere, Vol. 10, Pages 575: Photooxidation of Emissions from Firewood and Pellet Combustion Using a Photochemical Chamber Atmosphere doi: 10.3390/atmos10100575 Authors: Felipe Reyes Yeanice Vasquez Ernesto Gramsch Pedro Oyola Bernhard Rappenglück María A. Rubio The main emission source in Central and Southern Chilean cities is biomass combustion from residential heating and cooking due to old combustion technologies that are still widely utilized. In order to improve...
Tue Sep 24, 2019 03:00
Behavioral Sciences, Vol. 9, Pages 103: Education Level and Cigarette Smoking: Diminished Returns of Lesbian, Gay and Bisexual Individuals Behavioral Sciences doi: 10.3390/bs9100103 Authors: Shervin Assari Mohsen Bazargan Background: Education level is one of the strongest protective factors against high-risk behaviors such as cigarette smoking. Minorities’ Diminished Returns (MDRs), however, suggest that the protective effects of education level tend to be weaker for racial...
Tue Sep 24, 2019 03:00
Biology, Vol. 8, Pages 72: In Vitro Propagation of Rheophytic Orchid, Epipactis flava Seidenf.—A Comparison of Semi-Solid, Continuous Immersion and Temporary Immersion Systems Biology doi: 10.3390/biology8040072 Authors: Boworn Kunakhonnuruk Phithak Inthima Anupan Kongbangkerd Epipactis flava Seidenf. is an endangered Thai rheophytic orchid that has recently shown a rapid decrease in its natural habitat, prompting an urgent need for conservation using ex situ reintroduction methods....
Tue Sep 24, 2019 03:00
Biology, Vol. 8, Pages 71: Autophagy and Its Relationship to Epithelial to Mesenchymal Transition: When Autophagy Inhibition for Cancer Therapy Turns Counterproductive Biology doi: 10.3390/biology8040071 Authors: Guadalupe Rojas-Sanchez Israel Cotzomi-Ortega Nidia G. Pazos-Salazar Julio Reyes-Leyva Paola Maycotte The manipulation of autophagy for cancer therapy has gained recent interest in clinical settings. Although inhibition of autophagy is currently being used in clinical...
Tue Sep 24, 2019 03:00
Biomedicines, Vol. 7, Pages 74: The Role of Butyrate on Monocyte Migration and Inflammation Response in Patient with Type 2 Diabetes Mellitus Biomedicines doi: 10.3390/biomedicines7040074 Authors: Rahma Ayu Larasati Dante Saksono Harbuwono Ekowati Rahajeng Saraswati Pradipta Hanny Siti Nuraeni Andi Susilowati Heri Wibowo Type 2 Diabetes Mellitus (T2DM) is a very serious global problem. In Indonesia, this disease attacks at the most productive age; consequently, it can...
Tue Sep 24, 2019 03:00
Biomolecules, Vol. 9, Pages 525: All-Trans Retinoic Acid Attenuates Fibrotic Processes by Downregulating TGF-β1/Smad3 in Early Diabetic Nephropathy Biomolecules doi: 10.3390/biom9100525 Authors: Edith Sierra-Mondragon Rafael Rodríguez-Muñoz Carmen Namorado-Tonix Eduardo Molina-Jijon Daniel Romero-Trejo Jose Pedraza-Chaverri Jose L. Reyes Diabetic nephropathy (DN) involves damage associated to hyperglycemia and oxidative stress. Renal fibrosis is a major pathologic feature...
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Brain Sciences, Vol. 9, Pages 249: Systemic and CSF Interleukin-1α Expression in a Rabbit Closed Cranium Subarachnoid Hemorrhage Model: An Exploratory Study Brain Sciences doi: 10.3390/brainsci9100249 Authors: Croci Wanderer Strange Grüter Casoni Sivanrupan Widmer Di Santo Fandino Mariani Marbacher Background: The inflammatory pathway in cerebrospinal fluid (CSF) leads to delayed cerebral vasospasm (DCVS) and delayed cerebral ischemia (DCI) after...
Tue Sep 24, 2019 03:00
Brain Sciences, Vol. 9, Pages 248: Behavioral and Electrophysiological Arguments in Favor of a Relationship between Impulsivity, Risk-Taking, and Success on the Iowa Gambling Task Brain Sciences doi: 10.3390/brainsci9100248 Authors: Julie Giustiniani Coralie Joucla Djamila Bennabi Magali Nicolier Thibault Chabin Caroline Masse Benoît Trojak Pierre Vandel Emmanuel Haffen Damien Gabriel The aim of the present study was to investigate the relationship between...
Tue Sep 24, 2019 03:00
Cancers, Vol. 11, Pages 1424: DNA Methylation of Enhancer Elements in Myeloid Neoplasms: Think Outside the Promoters? Cancers doi: 10.3390/cancers11101424 Authors: Raquel Ordoñez Nicolás Martínez-Calle Xabier Agirre Felipe Prosper Gene regulation through DNA methylation is a well described phenomenon that has a prominent role in physiological and pathological cell-states. This epigenetic modification is usually grouped in regions denominated CpG islands, which frequently co-localize...
Tue Sep 24, 2019 03:00
Cancers, Vol. 11, Pages 1422: The Emerging Roles of mTORC1 in Macromanaging Autophagy Cancers doi: 10.3390/cancers11101422 Authors: Akpedje S. Dossou Alakananda Basu Autophagy is a process of self-degradation that enables the cell to survive when faced with starvation or stressful conditions. The mechanistic target of rapamycin (mTOR), also known as the mammalian target of rapamycin, plays a critical role in maintaining a balance between cellular anabolism and catabolism. mTOR complex...
Tue Sep 24, 2019 03:00
Cancers, Vol. 11, Pages 1423: Unraveling Heterogeneity in Epithelial Cell Fates of the Mammary Gland and Breast Cancer Cancers doi: 10.3390/cancers11101423 Authors: Alexandr Samocha Hanna Doh Kai Kessenbrock Jeroen P. Roose Fluidity in cell fate or heterogeneity in cell identity is an interesting cell biological phenomenon, which at the same time poses a significant obstacle for cancer therapy. The mammary gland seems a relatively straightforward organ with stromal cells and...
Tue Sep 24, 2019 03:00
Cancers, Vol. 11, Pages 1421: Impact of Fibroblast-Derived SPARC on Invasiveness of Colorectal Cancer Cells Cancers doi: 10.3390/cancers11101421 Authors: Daniel Drev Felix Harpain Andrea Beer Anton Stift Elisabeth S. Gruber Martin Klimpfinger Sabine Thalhammer Andrea Reti Lukas Kenner Michael Bergmann Brigitte Marian Secreted protein acidic and rich in cysteine (SPARC) is a matricellular protein modulating cell-matrix interactions and was found up-regulated...
Tue Sep 24, 2019 03:00
Cells, Vol. 8, Pages 1141: Impact of Diabetic Stress Conditions on Renal Cell Metabolome Cells doi: 10.3390/cells8101141 Authors: Lagies Bork Kaminski Troendle Zimmermann Huber Walz Lienkamp Kammerer Diabetic kidney disease is a major complication in diabetes mellitus, and the most common reason for end-stage renal disease. Patients suffering from diabetes mellitus encounter glomerular damage by basement membrane thickening, and develop albuminuria. Subsequently,...
Tue Sep 24, 2019 03:00
Cells, Vol. 8, Pages 1140: The Role of miRNAs in Immune Cell Development, Immune Cell Activation, and Tumor Immunity: With a Focus on Macrophages and Natural Killer Cells Cells doi: 10.3390/cells8101140 Authors: Shi Jun Xu Hong Tao Hu Hai Liang Li Suhwan Chang The tumor microenvironment (TME) is the primary arena where tumor cells and the host immune system interact. Bidirectional communication between tumor cells and the associated stromal cell types within the TME influences...
Tue Sep 24, 2019 03:00
Cells, Vol. 8, Pages 1138: “Hierarchy” and “Holacracy”; A Paradigm of the Hematopoietic System Cells doi: 10.3390/cells8101138 Authors: Takafumi Yokota The mammalian hematopoietic system has long been viewed as a hierarchical paradigm in which a small number of hematopoietic stem cells (HSCs) are located at the apex. HSCs were traditionally thought to be homogeneous and quiescent in a homeostatic state. However, recent observations, through extramedullary hematopoiesis and clonal assays,...
Tue Sep 24, 2019 03:00
Cells, Vol. 8, Pages 1139: Ketamine Increases Proliferation of Human iPSC-Derived Neuronal Progenitor Cells via Insulin-Like Growth Factor 2 and Independent of the NMDA Receptor Cells doi: 10.3390/cells8101139 Authors: Alessandra Grossert Narges Zare Mehrjardi Sarah J. Bailey Mark A. Lindsay Jürgen Hescheler Tomo Šarić Nicole Teusch The N-methyl-D-aspartate (NMDA) receptor antagonist ketamine offers promising perspectives for the treatment of major depressive disorder....
Tue Sep 24, 2019 03:00
Cells, Vol. 8, Pages 1137: Vacuolar H+-ATPase Subunit V0C Regulates Aerobic Glycolysis of Esophageal Cancer Cells via PKM2 Signaling Cells doi: 10.3390/cells8101137 Authors: Sung Wook Son Gia Cac Chau Seong-Tae Kim Sung Hee Um The vacuolar H+-adenosine triphosphatase (ATPase) subunit V0C (ATP6V0C), a proton-conducting, pore-forming subunit of vacuolar ATPase, maintains pH homeostasis and induces organelle acidification. The intracellular and extracellular pH of cancer cells...
Tue Sep 24, 2019 03:00
Cells, Vol. 8, Pages 1134: Potential Roles of Adiponectin Isoforms in Human Obesity with Delayed Wound Healing Cells doi: 10.3390/cells8101134 Authors: Jiyoon Ryu Colleen Loza Huan Xu Min Zhou Jason Hadley Jielei Wu Huayu You Huaiqing Wang Jihong Yang Juli Bai Feng Liu Christie Bialowas Lily Dong Adiponectin is an adipokine with anti-insulin resistance and anti-inflammatory functions. It exists in serum predominantly in three multimeric complexes:...
Tue Sep 24, 2019 03:00
Cells, Vol. 8, Pages 1135: MiR-20b Down-Regulates Intestinal Ferroportin Expression In Vitro and In Vivo Cells doi: 10.3390/cells8101135 Authors: Shuxia Jiang Xi Fang Mingni Liu Yingdong Ni Wenqiang Ma Ruqian Zhao Ferroportin (FPN) is the only known cellular iron exporter in mammalian. However, post-transcriptional regulation of intestinal FPN has not yet been completely understood. In this study, bioinformatics algorithms (TargetScan, PicTar, PITA, and miRanda) were applied...
Tue Sep 24, 2019 03:00
Cells, Vol. 8, Pages 1136: New Frontiers: ARID3a in SLE Cells doi: 10.3390/cells8101136 Authors: Joshua Garton M. David Barron Michelle L. Ratliff Carol F. Webb Systemic lupus erythematosus (SLE) is a devastating and heterogeneous autoimmune disease that affects multiple organs, and for which the underlying causes are unknown. The majority of SLE patients produce autoantibodies, have increased levels of type-I inflammatory cytokines, and can develop glomerulonephritis. Recent...
Tue Sep 24, 2019 03:00
Challenges, Vol. 10, Pages 37: Bringing Fronts Back: A Research Agenda to Investigate the Health and Well-Being Impacts of Front Gardens Challenges doi: 10.3390/challe10020037 Authors: Lauriane Suyin Chalmin-Pui Alistair Griffiths Jenny J. Roe Ross W. F. Cameron This perspective article proposes an agenda to investigate the impacts of front gardens (yards) on health and well-being. As front gardens are increasingly being paved over, significant ecological benefits will be lost....
Tue Sep 24, 2019 03:00
Diagnostics, Vol. 9, Pages 127: The Molecular Effects of Ionizing Radiations on Brain Cells: Radiation Necrosis vs. Tumor Recurrence Diagnostics doi: 10.3390/diagnostics9040127 Authors: Vincenzo Cuccurullo Giuseppe Danilo Di Stasio Giuseppe Lucio Cascini Gianluca Gatta Cataldo Bianco The central nervous system (CNS) is generally resistant to the effects of radiation, but higher doses, such as those related to radiation therapy, can cause both acute and long-term brain damage....
Tue Sep 24, 2019 03:00
Environments, Vol. 6, Pages 109: Correction: Ducey et al. Differences in Microbial Communities and Pathogen Survival Between a Covered and Uncovered Anaerobic Lagoon. Environments, 2019, 6, 91 Environments doi: 10.3390/environments6100109 Authors: Thomas F. Ducey Diana M. C. Rashash Ariel A. Szogi The authors would like to correct the published article [...]
Tue Sep 24, 2019 03:00
Foods, Vol. 8, Pages 437: Postprandial Glycemic and Insulinemic Effects of the Addition of Aqueous Extracts of Dried Corn Silk, Cumin Seed Powder or Tamarind Pulp, in Two Forms, Consumed with High Glycemic Index Rice Foods doi: 10.3390/foods8100437 Authors: Haldar Gan Tay Ponnalagu Henry Several plant-based traditional ingredients in Asia are anecdotally used for preventing and/or treating type 2 diabetes. We investigated three such widely consumed ingredients, namely...
Tue Sep 24, 2019 03:00
Foods, Vol. 8, Pages 436: Predicting the Quality of Meat: Myth or Reality? Foods doi: 10.3390/foods8100436 Authors: Cécile Berri Brigitte Picard Bénédicte Lebret Donato Andueza Florence Lefèvre Elisabeth Le Bihan-Duval Stéphane Beauclercq Pascal Chartrin Antoine Vautier Isabelle Legrand Jean-François Hocquette This review is aimed at providing an overview of recent advances made in the field of meat quality prediction, particularly in Europe. The different...
Tue Sep 24, 2019 03:00
Foods, Vol. 8, Pages 435: Determination of Xanthohumol in Hops, Food Supplements and Beers by HPLC Foods doi: 10.3390/foods8100435 Authors: Patricia Vázquez Loureiro Ignacio Hernández Jiménez Raquel Sendón Ana Rodriguez-Bernaldo de Quirós Letricia Barbosa-Pereira Xanthohumol (XN) is the main prenylated chalcone present in hops (Humulus lupulus) with high biological activity, and it is of great importance for human health because of its antioxidant, anti-inflammatory, immunosuppressive...
Tue Sep 24, 2019 03:00
Geriatrics, Vol. 4, Pages 53: Neuromuscular Electrical Stimulation Plus Rehabilitative Exercise as a Treatment for Dysphagia in Stroke and Non-Stroke Patients in an NHS Setting: Feasibility and Outcomes Geriatrics doi: 10.3390/geriatrics4040053 Authors: Nicola Martindale John Stephenson Sue Pownall Dysphagia is a debilitating condition with significant consequences in terms of physical and mental health. This study demonstrates that it is feasible to provide an intensive therapy...
Tue Sep 24, 2019 03:00
Heritage, Vol. 2, Pages 2704-2711: Bombed Archaeology: Towards a Precise Identification and a Safe Management of WWII’s Dangerous Unexploded Bombs Heritage doi: 10.3390/heritage2040167 Authors: Pier Matteo Barone The massive bombings during World War II (WWII) have had a lasting impact across the Italian landscape. The problem of dangerous unexploded bombs is particularly relevant since the bombsites are buried beneath the soil close to inhabited and/or touristic areas. Archaeological...
Tue Sep 24, 2019 03:00
Humanities, Vol. 8, Pages 155: Reading (with) Hannah Arendt: Aesthetic Representation for an Ethics of Alterity Humanities doi: 10.3390/h8040155 Authors: Andreea Deciu Ritivoi Hannah Arendt’s interest in literature was part of a broader concern, which was inspired by her reading of Kant, with the role played by aesthetic representation in ethical and political judgment. Her rich repertoire of writings about literature deserves to be considered alongside the works more commonly...
Tue Sep 24, 2019 03:00
IJERPH, Vol. 16, Pages 3577: Sleep Disturbance in Older Patients in the Emergency Department: Prevalence, Predictors and Associated Outcomes International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16193577 Authors: Helen Mannion D. William Molloy Rónán O’Caoimh Impaired sleep is common in hospital. Despite this, little is known about sleep disturbance among older adults attending Emergency Departments (ED), particularly overnight-boarders, those admitted...
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IJERPH, Vol. 16, Pages 3576: The Role of the Activation of the TRPV1 Receptor and of Nitric Oxide in Changes in Endothelial and Cardiac Function and Biomarker Levels in Hypertensive Rats International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16193576 Authors: Juan Carlos Torres-Narváez Israel Pérez-Torres Vicente Castrejón-Téllez Elvira Varela-López Víctor Hugo Oidor-Chan Verónica Guarner-Lans Álvaro Vargas-González Raúl Martínez-Memije Pedro...
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IJERPH, Vol. 16, Pages 3562: Higher Mortality Rate in Moderate-to-Severe Thoracoabdominal Injury Patients with Admission Hyperglycemia Than Nondiabetic Normoglycemic Patients International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16193562 Authors: Wei-Ti Su Shao-Chun Wu Sheng-En Chou Chun-Ying Huang Shiun-Yuan Hsu Hang-Tsung Liu Ching-Hua Hsieh Background: Hyperglycemia at admission is associated with an increase in worse outcomes in trauma...
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IJERPH, Vol. 16, Pages 3574: Effects of Orientations, Aspect Ratios, Pavement Materials and Vegetation Elements on Thermal Stress inside Typical Urban Canyons International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16193574 Authors: Lobaccaro Acero Martinez Padro Laburu Fernandez The analysis of local climate conditions to test artificial urban boundaries and related climate hazards through modelling tools should become a common practice...
Tue Sep 24, 2019 03:00
IJERPH, Vol. 16, Pages 3575: Predicting Behavioral Intentions Related to Cervical Cancer Screening Using a Three-Level Model for the TPB and SCT in Nanjing, China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16193575 Authors: Zhang Sha Gu Li Yang Zhu He : Objective: Exploring how the theory of planned behavior (TPB), social capital theory (SCT), cervical cancer knowledge (CCK), and demographic variables predict behavioral...
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