Correlation of factors associated with postoperative infection in patients with malignant oral and maxillofacial tumours: a logistic regression analysis.

Guo Z1, Zhang J2, Gong Z3, Jing S4.

Author information

1

Oncology Department of Oral and Maxillofacial Surgery of The First Affiliated Hospital of Xinjiang Medical University, Xin Jiang Province, Urumqi, 830054, China.

2

Hairong Dental Clinic, Xinjiang Uygur Autonomous Region, Urumqi, 830002, China.

3

Oncology Department of Oral and Maxillofacial Surgery of The First Affiliated Hospital of Xinjiang Medical University, Xin Jiang Province, Urumqi, 830054, China. Electronic address: gump0904@aliyun.com.

4

Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430074.

Abstract

Patients with oral and maxillofacial malignant tumours have a relatively high incidence of postoperative infections. We have analysed the risk factors and the distribution of pathogens in infected patients to try and find out how to prevent them. We recruited 312 patients over 60 years old with malignant oral and maxillofacial tumours and investigated their incidence of postoperative infection between January 2007 and December 2017. Some factors were included in one way and multifactorial logistic analyses to find out which risk factors were likely to be associated with postoperative infections. Thirty-nine of the 312 (12.5%) developed postoperative infections, mainly at the surgical site (n = 21) and in the lower respiratory tract (n = 14). Pathogens were isolated from all patients and comprised aerobic (n = 4) and anaerobic (n = 5) bacteria, together with mixed infections (n = 30). Univariate analysis showed that age, size and site of tumour, body-mass index (BMI), diabetes, and duration of operation were risk factors. Multivariate logistic analyses, however, showed that BMI, the presence of diabetes, duration of operation, and American Society of Anesthesiologists (ASA) score were the main independent risk factors for postoperative infection. We conclude that there are abundant risk factors for postoperative infection in these patients, and it is important that they are evaluated preoperatively so that suitable postoperative treatments can be given.

Copyright © 2019 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

KEYWORDS:

Malignant tumors; Oral and maxillofacial region; Post-op infection; Risk factor

PMID:

 

31006505

 

DOI:

 

10.1016/j.bjoms.2019.04.003

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