IJERPH, Vol. 16, Pages 5040: Critical Appraisal of Qualitative Studies of Muslim Females’ Perceptions of Physical Activity Barriers and Facilitators International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16245040 Authors: David Kahan Muslim women’s perceptions of cultural, religious, and secular determinants of physical activity have been studied for many years, with information typically acquired through focus groups or interviews. Multiple reviews...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6262: Rheology of Dispersions of High-Aspect-Ratio Nanofibers Assembled from Elastin-Like Double-Hydrophobic Polypeptides International Journal of Molecular Sciences doi: 10.3390/ijms20246262 Authors: Ayae Sugawara-Narutaki Sawako Yasunaga Yusuke Sugioka Duc H. T. Le Issei Kitamura Jin Nakamura Chikara Ohtsuki Elastin-like polypeptides (ELPs) are promising candidates for fabricating tissue-engineering scaffolds that mimic the extracellular environment...
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IJMS, Vol. 20, Pages 6261: Antiviral Activity of Benzoic Acid Derivative NC-5 Against Influenza A Virus and Its Neuraminidase Inhibition International Journal of Molecular Sciences doi: 10.3390/ijms20246261 Authors: Min Guo Jiawei Ni Jie Yu Jing Jin Lingman Ma Huixing Zhang Dechuan Wang Xue Zhang Jie Dou Changlin Zhou The currently available drugs against influenza A virus primarily target neuraminidase (NA) or the matrix protein 2 (M2) ion channel. The emergence...
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IJMS, Vol. 20, Pages 6260: Developing Gold Nanoparticles-Conjugated Aflatoxin B1 Antifungal Strips International Journal of Molecular Sciences doi: 10.3390/ijms20246260 Authors: Tobiloba Sojinrin Kangze Liu Kan Wang Daxiang Cui Hugh J. Byrne James F. Curtin Furong Tian Lateral flow immunochromatographic assays are a powerful diagnostic tool for point-of-care tests, based on their simplicity, specificity, and sensitivity. In this study, a rapid and sensitive gold nanoparticle...
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IJMS, Vol. 20, Pages 6258: High Mobility Group Box-1 and Diabetes Mellitus Complications: State of the Art and Future Perspectives International Journal of Molecular Sciences doi: 10.3390/ijms20246258 Authors: Biscetti Rando Nardella Cecchini Pecorini Landolfi Flex Diabetes mellitus (DM) is an endemic disease, with growing health and social costs. The complications of diabetes can affect potentially all parts of the human body, from the heart to the kidneys,...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6256: Structural and Dynamic Characterizations Highlight the Deleterious Role of SULT1A1 R213H Polymorphism in Substrate Binding International Journal of Molecular Sciences doi: 10.3390/ijms20246256 Authors: Raju Dash Md. Chayan Ali Nayan Dash Md. Abul Kalam Azad S. M. Zahid Hosen Md. Abdul Hannan Il Soo Moon Sulfotransferase 1A1 (SULT1A1) is responsible for catalyzing various types of endogenous and exogenous compounds. Accumulating data indicates...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6257: The Emerging Landscape of p53 Isoforms in Physiology, Cancer and Degenerative Diseases International Journal of Molecular Sciences doi: 10.3390/ijms20246257 Authors: Thineskrishna Anbarasan Jean-Christophe Bourdon p53, first described four decades ago, is now established as a master regulator of cellular stress response, the “guardian of the genome”. p53 contributes to biological robustness by behaving in a cellular-context dependent...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6259: The Detection and Partial Localisation of Heteroplasmic Mutations in the Mitochondrial Genome of Patients with Diabetic Retinopathy International Journal of Molecular Sciences doi: 10.3390/ijms20246259 Authors: Malik Rosa de Menezes Tamang Hamid Naik Parsade Sivaprasad Diabetic retinopathy (DR) is a common complication of diabetes and a major cause of acquired blindness in adults. Mitochondria are cellular organelles involved in...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6255: Effect of AQP Inhibition on Boar Sperm Cryotolerance Depends on the Intrinsic Freezability of the Ejaculate International Journal of Molecular Sciences doi: 10.3390/ijms20246255 Authors: Ariadna Delgado-Bermúdez Marc Llavanera Sandra Recuero Yentel Mateo-Otero Sergi Bonet Isabel Barranco Beatriz Fernandez-Fuertes Marc Yeste Aquaporins (AQPs) are transmembrane channels with permeability to water and small solutes that can be classified according...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6253: Acid Sphingomyelinase Deficiency Ameliorates Farber Disease International Journal of Molecular Sciences doi: 10.3390/ijms20246253 Authors: Beckmann Becker Kadow Schumacher Kramer Kühn Schulz-Schaeffer Edwards Kleuser Gulbins Carpinteiro Farber disease is a rare lysosomal storage disorder resulting from acid ceramidase deficiency and subsequent ceramide accumulation. No treatments for Farber disease are clinically available,...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6254: Prostaglandin E2/EP Signaling in the Tumor Microenvironment of Colorectal Cancer International Journal of Molecular Sciences doi: 10.3390/ijms20246254 Authors: Rei Mizuno Kenji Kawada Yoshiharu Sakai The number of colorectal cancer (CRC) patients is increasing worldwide. Accumulating evidence has shown that the tumor microenvironment (TME), including macrophages, neutrophils, and fibroblasts, plays an important role in the development and progression...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6252: The Major Factors Causing the Microspore Abortion of Genic Male Sterile Mutant NWMS1 in Wheat (Triticum aestivum L.) International Journal of Molecular Sciences doi: 10.3390/ijms20246252 Authors: Li Zhang Li Niu Xu Jiao An Jiang Li Niu Male sterility is a valuable trait for genetic research and production application of wheat (Triticum aestivum L.). NWMS1, a novel typical genic male sterility mutant, was obtained from Shengnong...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6251: Delayed Dopamine Dysfunction and Motor Deficits in Female Parkinson Model Mice International Journal of Molecular Sciences doi: 10.3390/ijms20246251 Authors: Yuan-Hao Chen Vicki Wang Eagle Yi-Kung Huang Yu-Ching Chou Tung-Tai Kuo Lars Olson Barry J. Hoffer This study analyzed gender differences in the progressive dopamine (DA) deficiency phenotype in the MitoPark (MP) mouse model of Parkinson’s disease (PD) with progressive loss...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6250: Effects of Dietary Lipid Composition and Fatty Acid Desaturase 2 Expression in Broodstock Gilthead Sea Bream on Lipid Metabolism-Related Genes and Methylation of the fads2 Gene Promoter in Their Offspring International Journal of Molecular Sciences doi: 10.3390/ijms20246250 Authors: Serhat Turkmen Erick Perera Maria J. Zamorano Paula Simó-Mirabet Hanlin Xu Jaume Pérez-Sánchez Marisol Izquierdo Polyunsaturated fatty acids (PUFA) in parental...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6248: Metabolomic Profile of BALB/c Macrophages Infected with Leishmania amazonensis: Deciphering L-Arginine Metabolism International Journal of Molecular Sciences doi: 10.3390/ijms20246248 Authors: Sandra Marcia Muxel Maricruz Mamani-Huanca Juliana Ide Aoki Ricardo Andrade Zampieri Lucile Maria Floeter-Winter Ángeles López-Gonzálvez Coral Barbas Background: Leishmaniases are neglected tropical diseases that are caused by Leishmania, being endemic...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6247: Novel JAG1 Deletion Variant in Patient with Atypical Alagille Syndrome International Journal of Molecular Sciences doi: 10.3390/ijms20246247 Authors: Emanuele Micaglio Andreea Alina Andronache Paola Carrera Michelle M. Monasky Emanuela T. Locati Barbara Pirola Silvia Presi Mario Carminati Maurizio Ferrari Alessandro Giamberti Carlo Pappone Alagille syndrome (AGS) is an autosomal-dominant disorder characterized by various degrees...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6249: Deciphering miRNAs’ Action through miRNA Editing International Journal of Molecular Sciences doi: 10.3390/ijms20246249 Authors: Marta Correia de Sousa Monika Gjorgjieva Dobrochna Dolicka Cyril Sobolewski Michelangelo Foti MicroRNAs (miRNAs) are small non-coding RNAs with the capability of modulating gene expression at the post-transcriptional level either by inhibiting messenger RNA (mRNA) translation or by promoting mRNA degradation. The outcome...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6245: Novel Drug-Like Somatostatin Receptor 4 Agonists are Potential Analgesics for Neuropathic Pain International Journal of Molecular Sciences doi: 10.3390/ijms20246245 Authors: Boglárka Kántás Rita Börzsei Éva Szőke Péter Bánhegyi Ádám Horváth Ágnes Hunyady Éva Borbély Csaba Hetényi Erika Pintér Zsuzsanna Helyes Somatostatin released from the capsaicin-sensitive sensory nerves mediates analgesic and anti-inflammatory effects via the...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6246: A Computer Model of Oxygen Dynamics in the Cortex of the Rat Kidney at the Cell-Tissue Level International Journal of Molecular Sciences doi: 10.3390/ijms20246246 Authors: Vivien Aubert Jacques Kaminski François Guillaud Thierry Hauet Patrick Hannaert The renal cortex drives renal function. Hypoxia/reoxygenation are primary factors in ischemia-reperfusion (IR) injuries, but renal oxygenation per se is complex and awaits full elucidation. Few mathematical...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6244: Cloning and Partial Characterization of an Endo-α-(1→6)-d-Mannanase Gene from Bacillus circulans International Journal of Molecular Sciences doi: 10.3390/ijms20246244 Authors: Shiva kumar Angala Wei Li Zuzana Palčeková Lu Zou Todd L. Lowary Michael R. McNeil Mary Jackson Mycobacteria produce two major lipoglycans, lipomannan (LM) and lipoarabinomannan (LAM), whose broad array of biological activities are tightly related to the fine details...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6242: Osteogenic Differentiation of Human Adipose Tissue-Derived MSCs by Non-Toxic Calcium Poly(ethylene phosphate)s International Journal of Molecular Sciences doi: 10.3390/ijms20246242 Authors: Ilya Nifant’ev Tatiana Bukharova Alexander Dyakonov Dmitry Goldshtein Elena Galitsyna Maxim Kosarev Andrey Shlyakhtin Dmitry Gavrilov Pavel Ivchenko There is a current clinical need for the development of bone void fillers and bioactive bone graft...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6241: Do Mutations Turn p53 into an Oncogene? International Journal of Molecular Sciences doi: 10.3390/ijms20246241 Authors: Consuelo Pitolli Ying Wang Mara Mancini Yufang Shi Gerry Melino Ivano Amelio The key role of p53 as a tumor suppressor became clear when it was realized that this gene is mutated in 50% of human sporadic cancers, and germline mutations expose carriers to cancer risk throughout their lifespan. Mutations in this gene not only abolish...
Wed Dec 11, 2019 02:00
IJMS, Vol. 20, Pages 6243: Systematic Comparison of the Effect of Four Clinical-Grade Platelet Rich Hemoderivatives on Osteoblast Behaviour International Journal of Molecular Sciences doi: 10.3390/ijms20246243 Authors: Tulio Fernández-Medina Cedryck Vaquette Sašo Ivanovski Hemoderivatives have utilized in an empirical manner, driven by clinical considerations, leading to the development of a plethora of manufacturing protocols. The purpose of this study was to investigate the composition...
Wed Dec 11, 2019 02:00
JCM, Vol. 8, Pages 2190: Toward Engineering the Mannose 6-Phosphate Elaboration Pathway in Plants for Enzyme Replacement Therapy of Lysosomal Storage Disorders Journal of Clinical Medicine doi: 10.3390/jcm8122190 Authors: Ying Zeng Xu He Tatyana Danyukova Sandra Pohl Allison R. Kermode Mucopolysaccharidosis (MPS) I is a severe lysosomal storage disease caused by α-L-iduronidase (IDUA) deficiency, which results in accumulation of non-degraded glycosaminoglycans in...
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JCM, Vol. 8, Pages 2188: Dose-Ranging Study of Ramosetron for the Prevention of Nausea and Vomiting after Laparoscopic Gynecological Surgery: A Prospective Randomized Study Journal of Clinical Medicine doi: 10.3390/jcm8122188 Authors: Cho Kim Lee Yoo Patients undergoing laparoscopic gynecologic surgery and receiving postoperative analgesia with opioids have a high risk of postoperative nausea and vomiting (PONV). We compared the antiemetic efficacy of three doses of ramosetron...
Wed Dec 11, 2019 02:00
JCM, Vol. 8, Pages 2189: Management of Immunosuppression in Kidney Transplant Recipients Who Develop Malignancy Journal of Clinical Medicine doi: 10.3390/jcm8122189 Authors: Yang Thamcharoen Cardarelli The risk of cancer increases after transplantation. However, the consensus on immunosuppression (IS) adjustment after diagnosis of malignancy is lacking. Our study aims to assess the impact of IS adjustment on mortality of post-kidney transplant patients and allograft outcomes....
Wed Dec 11, 2019 02:00
JCM, Vol. 8, Pages 2187: Renal Tubular TRPA1 as a Risk Factor for Recovery of Renal Function from Acute Tubular Necrosis Journal of Clinical Medicine doi: 10.3390/jcm8122187 Authors: Wu Wu Su Kou Kor Lee Tarng Background: Transient receptor potential ankyrin 1 (TRPA1), a redox-sensing Ca2+-influx channel, serves as a gatekeeper for inflammation. However, the role of TRPA1 in kidney injury remains elusive. Methods: The retrospective cohort study recruited 46 adult...
Wed Dec 11, 2019 02:00
JCM, Vol. 8, Pages 2185: One-Stop Management of 230 Consecutive Acute Stroke Patients: Report of Procedural Times and Clinical Outcome Journal of Clinical Medicine doi: 10.3390/jcm8122185 Authors: Marios-Nikos Psychogios Ilko L. Maier Ioannis Tsogkas Amélie Carolina Hesse Alex Brehm Daniel Behme Marlena Schnieder Katharina Schregel Ismini Papageorgiou David S. Liebeskind Mayank Goyal Mathias Bähr Michael Knauth Jan Liman Background and purpose:...
Wed Dec 11, 2019 02:00
JCM, Vol. 8, Pages 2183: Influence of Biologically Oriented Preparation Technique on Peri-Implant Tissues; Prospective Randomized Clinical Trial with Three-Year Follow-Up. Part I: Hard Tissues Journal of Clinical Medicine doi: 10.3390/jcm8122183 Authors: Rubén Agustín-Panadero Naia Bustamante-Hernández María Fernanda Solá-Ruíz Álvaro Zubizarreta-Macho Antonio Fons-Font Lucía Fernández-Estevan Purpose: The objective of this prospective randomized clinical trial (RCT) was...
Wed Dec 11, 2019 02:00
JCM, Vol. 8, Pages 2184: A Humanized Bone Niche Model Reveals Bone Tissue Preservation Upon Targeting Mitochondrial Complex I in Pseudo-Orthotopic Osteosarcoma Journal of Clinical Medicine doi: 10.3390/jcm8122184 Authors: Ivana Kurelac Ander Abarrategi Moira Ragazzi Luisa Iommarini Nikkitha Umesh Ganesh Thomas Snoeks Dominique Bonnet Anna Maria Porcelli Ilaria Malanchi Giuseppe Gasparre A cogent issue in cancer research is how to account for the effects of...
Wed Dec 11, 2019 02:00
JCM, Vol. 8, Pages 2186: Exercise Training Enhances Platelet Mitochondrial Bioenergetics in Stroke Patients: A Randomized Controlled Trial Journal of Clinical Medicine doi: 10.3390/jcm8122186 Authors: Chih-Chin Hsu Hsing-Hua Tsai Tieh-Cheng Fu Jong-Shyan Wang Exercise training (ET) may impact physical fitness by affecting mitochondrial functions. This study aimed to elucidate the effect of ET on aerobic capacity and platelet mitochondrial bioenergetics (MTB) in stroke patients....
Wed Dec 11, 2019 02:00
JCM, Vol. 8, Pages 2182: Efficacy and Safety of Injectable and Oral Antibiotics in Treating Gonorrhea: A Systematic Review and Network Meta-Analysis Journal of Clinical Medicine doi: 10.3390/jcm8122182 Authors: Jiaru Yang Subhash Dhital Thomas Naderer Gonorrhea is the second most frequently reported sexually transmitted infectious disease of bacterial origin in the world. Current empiric therapies rely on broad-spectrum antibiotics. However, treatment options are becoming limited...
Wed Dec 11, 2019 02:00
JCM, Vol. 8, Pages 2181: Retinal Microperimetry: A Useful Tool for Detecting Insulin Resistance-Related Cognitive Impairment in Morbid Obesity Journal of Clinical Medicine doi: 10.3390/jcm8122181 Authors: Andreea Ciudin Angel Ortiz Enzamaria Fidilio Diana Romero Marta Sánchez Marta Comas Oscar Gonzalez Ramon Vilallonga Olga Simó-Servat Cristina Hernández Rafael Simó Background: There is clear association between type 2 diabetes (T2D) and cognitive decline....
Wed Dec 11, 2019 02:00
JCM, Vol. 8, Pages 2180: Neoadjuvant Metformin Added to Systemic Therapy Decreases the Proliferative Capacity of Residual Breast Cancer Journal of Clinical Medicine doi: 10.3390/jcm8122180 Authors: Eugeni Lopez-Bonet Maria Buxó Elisabet Cuyàs Sonia Pernas Joan Dorca Isabel Álvarez Susana Martínez Jose Manuel Pérez-Garcia Norberto Batista-López César A. Rodríguez-Sánchez Kepa Amillano Severina Domínguez Maria Luque Idoia Morilla Agostina Stradella Gemma...
Wed Dec 11, 2019 02:00
JCM, Vol. 8, Pages 2179: Efficacy Study of Anti-Endomysium Antibodies for Celiac Disease Diagnosis: A Retrospective Study in a Spanish Pediatric Population Journal of Clinical Medicine doi: 10.3390/jcm8122179 Authors: María Roca Ester Donat Natalia Marco-Maestud Etna Masip David Hervás-Marín David Ramos Begoña Polo Carmen Ribes-Koninckx The aim of this study was to assess the efficacy of anti-endomysium antibodies (EMA) as a serological marker for celiac disease...
Wed Dec 11, 2019 02:00
Metabolites, Vol. 9, Pages 300: Metabolomics of Small Intestine Neuroendocrine Tumors and Related Hepatic Metastases Metabolites doi: 10.3390/metabo9120300 Authors: Alessio Imperiale Gilles Poncet Pietro Addeo Elisa Ruhland Colette Roche Stephanie Battini A. Ercument Cicek Marie Pierrette Chenard Valérie Hervieu Bernard Goichot Philippe Bachellier Thomas Walter Izzie Jacques Namer To assess the metabolomic fingerprint of small intestine neuroendocrine...
Wed Dec 11, 2019 02:00
MPs, Vol. 2, Pages 91: Using to Reconstruct Radiation Transport through Complex Archaeological Environments Methods and Protocols doi: 10.3390/mps2040091 Authors: Amber G.E. Hood Edmund G. Highcock The DosiVox programme is used to reconstruct radiation transport in complex depositional environments. Using two archaeological case studies from ancient Egypt, the burial environments for a selection of ceramic vessels are reconstructed using the DosiVox programme, allowing the simulation...
Wed Dec 11, 2019 02:00
Microorganisms, Vol. 7, Pages 684: Synergistic Effects of Probiotics and Phytobiotics on the Intestinal Microbiota in Young Broiler Chicken Microorganisms doi: 10.3390/microorganisms7120684 Authors: Ren Vahjen Dadi Saliu Boroojeni Zentek Probiotics and phytobiotics have been studied as in-feed antibiotic alternatives for decades, yet there are no studies on their possible symbiotic effects. In the present study, newly hatched chickens were fed with feeds supplemented...
Wed Dec 11, 2019 02:00
Microorganisms, Vol. 7, Pages 682: Temperature Effects on Methanogenesis and Sulfidogenesis during Anaerobic Digestion of Sulfur-Rich Macroalgal Biomass in Sequencing Batch Reactors Microorganisms doi: 10.3390/microorganisms7120682 Authors: Jung Kim Lee Methanogenesis and sulfidogenesis, the major microbial reduction reactions occurring in the anaerobic digestion (AD) process, compete for common substrates. Therefore, the balance between methanogenic and sulfidogenic activities...
Wed Dec 11, 2019 02:00
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