Cancers, Vol. 12, Pages 26: When RAD52 Allows Mitosis to Accept Unscheduled DNA Synthesis Cancers doi: 10.3390/cancers12010026 Authors: Franchet Hoffmann Faithful duplication of the human genome during the S phase of cell cycle and accurate segregation of sister chromatids in mitosis are essential for the maintenance of chromosome stability from one generation of cells to the next. Cells that are copying their DNA in preparation for division can suffer from ‘replication...
Thu Dec 19, 2019 02:00
Cancers, Vol. 12, Pages 27: Allometric Scaling Approaches for Predicting Human Pharmacokinetic of a Locked Nucleic Acid Oligonucleotide Targeting Cancer-Associated miR-221 Cancers doi: 10.3390/cancers12010027 Authors: Di Martino Arbitrio Fonsi Erratico Scionti Caracciolo Tagliaferri Tassone : LNA-i-miR-221 is a novel phosphorothioate backbone 13-mer locked nucleic acid oligonucleotide-targeting microRNA-221 designed for the treatment of human malignancies....
Thu Dec 19, 2019 02:00
Cancers, Vol. 12, Pages 24: Activation of STAT3 and STAT5 Signaling in Epithelial Ovarian Cancer Progression: Mechanism and Therapeutic Opportunity Cancers doi: 10.3390/cancers12010024 Authors: Wu Sundararajan Sheu Huang Wei Abstract: Epithelial ovarian cancer (EOC) is the most lethal of all gynecologic malignancies. Despite advances in surgical and chemotherapeutic options, most patients with advanced EOC have a relapse within three years of diagnosis. Unfortunately,...
Thu Dec 19, 2019 02:00
Cancers, Vol. 12, Pages 25: Nanomaterials as Inhibitors of Epithelial Mesenchymal Transition in Cancer Treatment Cancers doi: 10.3390/cancers12010025 Authors: Cordani Strippoli Somoza Abstract: Epithelial-mesenchymal transition (EMT) has emerged as a key regulator of cell invasion and metastasis in cancers. Besides the acquisition of migratory/invasive abilities, the EMT process is tightly connected with the generation of cancer stem cells (CSCs), thus contributing to chemoresistance....
Thu Dec 19, 2019 02:00
Cancers, Vol. 12, Pages 23: Interferon Is Superior to Direct Acting Antiviral Therapy in Tertiary Prevention of Early Recurrence of Hepatocellular Carcinoma Cancers doi: 10.3390/cancers12010023 Authors: Teng Jeng Yang Chen Hsieh Huang Lin Lin Lin Sheen The elimination of chronic hepatitis C infection (CHC) by pegylated interferon plus ribavirin (Peg-IFN/RBV) decreases hepatocellular carcinoma (HCC) recurrence rate. However, the tertiary prevention...
Thu Dec 19, 2019 02:00
Cancers, Vol. 12, Pages 22: Overexpression of Mitochondrial IF1 Prevents Metastatic Disease of Colorectal Cancer by Enhancing Anoikis and Tumor Infiltration of NK Cells Cancers doi: 10.3390/cancers12010022 Authors: Lucía González-Llorente Fulvio Santacatterina Ana García-Aguilar Cristina Nuevo-Tapioles Sara González-García Zuzana Tirpakova María Luisa Toribio José M. Cuezva Increasing evidences show that the ATPase Inhibitory Factor 1 (IF1), the physiological inhibitor...
Thu Dec 19, 2019 02:00
Cancers, Vol. 12, Pages 15: Therapeutic Monoclonal Antibodies and Antibody Products: Current Practices and Development in Multiple Myeloma Cancers doi: 10.3390/cancers12010015 Authors: Bonello Mina Boccadoro Gay Immunotherapy is the latest innovation for the treatment of multiple myeloma (MM). Monoclonal antibodies (mAbs) entered the clinical practice and are under evaluation in clinical trials. MAbs can target highly selective and specific antigens on the cell surface of...
Thu Dec 19, 2019 02:00
Cancers, Vol. 12, Pages 16: Prognostic and Predictive Value of PBRM1 in Clear Cell Renal Cell Carcinoma Cancers doi: 10.3390/cancers12010016 Authors: Carril-Ajuria Santos Roldán-Romero Rodriguez-Antona de Velasco Renal cell carcinoma (RCC) is the most frequent kidney solid tumor, the clear cell RCC (ccRCC) being the major histological subtype. The probability of recurrence and the clinical behavior of ccRCC will greatly depend on the different clinical and histopathological...
Thu Dec 19, 2019 02:00
Cancers, Vol. 12, Pages 20: Management of Liver Oligometastatic Esophageal Cancer: Overview and Critical Analysis of the Different Loco-Regional Treatments Cancers doi: 10.3390/cancers12010020 Authors: Fabio Procopio Salvatore Marano Damiano Gentile Anna Da Roit Silvia Basato Pietro Riva Ferdinando De Vita Guido Torzilli Carlo Castoro Esophageal cancer (EC) is an aggressive disease that is associated with a poor prognosis. Since metastastic EC is usually considered...
Thu Dec 19, 2019 02:00
Cancers, Vol. 12, Pages 19: STAT3 Activation and Oncogenesis in Lymphoma Cancers doi: 10.3390/cancers12010019 Authors: Fen Zhu Kevin Boyang Wang Lixin Rui Signal transducer and activator of transcription 3 (STAT3) is an important and the most studied transcription factor in the Janus kinase (JAK)/STAT signaling pathway. STAT3 mediates the expression of various genes that play a critical role in many cellular and biological processes, such as cell proliferation, survival, differentiation,...
Thu Dec 19, 2019 02:00
Cancers, Vol. 12, Pages 18: Brain Invasion along Perivascular Spaces by Glioma Cells: Relationship with Blood–Brain Barrier Cancers doi: 10.3390/cancers12010018 Authors: Simone Pacioni Quintino Giorgio D’Alessandris Mariachiara Buccarelli Alessandra Boe Maurizio Martini Luigi Maria Larocca Giulia Bolasco Lucia Ricci-Vitiani Maria Laura Falchetti Roberto Pallini The question whether perivascular glioma cells invading the brain far from the tumor bulk may disrupt...
Thu Dec 19, 2019 02:00
Cancers, Vol. 12, Pages 17: Liquid Biopsy in Non-Small Cell Lung Cancer: Highlights and Challenges Cancers doi: 10.3390/cancers12010017 Authors: Erika Rijavec Simona Coco Carlo Genova Giovanni Rossi Luca Longo Francesco Grossi Non-small cell lung cancer is one leading cause of death worldwide, and patients would greatly benefit from an early diagnosis. Since targeted and immunotherapies have emerged as novel approaches for more tailored treatments, repeated assessments...
Thu Dec 19, 2019 02:00
Cancers, Vol. 12, Pages 14: Genetically Engineered Mouse Models for Liver Cancer Cancers doi: 10.3390/cancers12010014 Authors: Cho Ro Seo Jeon Moon Kim Kim Liver cancer is the fourth leading cause of cancer-related death globally, accounting for approximately 800,000 deaths annually. Hepatocellular carcinoma (HCC) is the most common type of liver cancer, comprising approximately 80% of cases. Murine models of HCC, such as chemically-induced models, xenograft...
Thu Dec 19, 2019 02:00
Cancers, Vol. 12, Pages 21: Chaperoning STAT3/5 by Heat Shock Proteins: Interest of Their Targeting in Cancer Therapy Cancers doi: 10.3390/cancers12010021 Authors: Gaëtan Jego François Hermetet François Girodon Carmen Garrido While cells from multicellular organisms are dependent upon exogenous signals for their survival, growth, and proliferation, commitment to a specific cell fate requires the correct folding and maturation of proteins, as well as the degradation of misfolded...
Thu Dec 19, 2019 02:00
Cancers, Vol. 12, Pages 13: Overexpression of PSAT1 Gene is a Favorable Prognostic Marker in Lower-Grade Gliomas and Predicts a Favorable Outcome in Patients with IDH1 Mutations and Chromosome 1p19q Codeletion Cancers doi: 10.3390/cancers12010013 Authors: Huang Chan Huang Lin Patients with lower-grade gliomas (LGGs) have highly diverse clinical outcomes. Although histological features and molecular markers have been used to predict prognosis, the identification of new biomarkers...
Wed Dec 18, 2019 02:00
Cancers, Vol. 12, Pages 12: Polyclonal Immunoglobulin Recovery after Autologous Stem Cell Transplantation Is an Independent Prognostic Factor for Survival Outcome in Patients with Multiple Myeloma Cancers doi: 10.3390/cancers12010012 Authors: Ozaki Harada Yagi Sekimoto Shibata Shigekiyo Fujii Nakamura Miki Kagawa Abe We retrospectively analyzed multiple myeloma (MM) patients who underwent autologous stem cell transplantation (ASCT) without maintenance...
Wed Dec 18, 2019 02:00
Cancers, Vol. 12, Pages 11: The Composition of Surgical Wound Fluids from Breast Cancer Patients is Affected by Intraoperative Radiotherapy Treatment and Depends on the Molecular Subtype of Breast Cancer Cancers doi: 10.3390/cancers12010011 Authors: Kulcenty Piotrowski Wróblewska Wasiewicz Suchorska Invasive oncological procedures affect the remaining tumor cells by increasing their survival, proliferation, and migration through the induction of wound healing response....
Wed Dec 18, 2019 02:00
Cancers, Vol. 12, Pages 9: RECIL versus Lugano for Treatment Response Assessment in FDG-Avid Non-Hodgkin Lymphomas: A Head-to-Head Comparison in 54 Patients Cancers doi: 10.3390/cancers12010009 Authors: Berzaczy Haug Staber Raderer Kiesewetter Jaeger Kornauth Simonitsch-Klupp Mayerhoefer The response evaluation criteria in lymphoma (RECIL) classification for lymphoma treatment response assessment was introduced in 2017, but it has not yet been compared...
Wed Dec 18, 2019 02:00
Cancers, Vol. 12, Pages 10: Maspin is a PTEN-Upregulated and p53-Upregulated Tumor Suppressor Gene and Acts as an HDAC1 Inhibitor in Human Bladder Cancer Cancers doi: 10.3390/cancers12010010 Authors: Lin Tsui Chang Hou Feng Juang Maspin is a member of the clade B serine protease inhibitor superfamily and exhibits diverse regulatory effects in various types of solid tumors. We compared the expressions of maspin and determined its potential biological functions and...
Wed Dec 18, 2019 02:00
Cancers, Vol. 12, Pages 7: Overexpression of p62/IMP2 can Promote Cell Migration in Hepatocellular Carcinoma via Activation of the Wnt/β-Catenin Pathway Cancers doi: 10.3390/cancers12010007 Authors: Xing Li Wang Li Shi Qin Zhang Ma Francia Zhang p62/IMP2 is an oncofetal protein that was first reported as a tumor-associated antigen in hepatocellular carcinoma (HCC). In our previous studies, we demonstrated a high frequency of p62/IMP2 autoantibodies...
Wed Dec 18, 2019 02:00
Cancers, Vol. 12, Pages 8: Comparison of Oncologic Outcomes Between Two Alternative Sequences with Abiraterone Acetate and Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer: A Systematic Review and Meta-Analysis Cancers doi: 10.3390/cancers12010008 Authors: Chung Kang Kim Kim Lee Hong Cho Sequential treatment of androgen receptor axis targeted agents (ARAT), abiraterone acetate (ABI) and enzalutamide (ENZA), in metastatic castration-resistant...
Wed Dec 18, 2019 02:00
Cancers, Vol. 12, Pages 5: PARP1 Inhibition Augments UVB-Mediated Mitochondrial Changes—Implications for UV-Induced DNA Repair and Photocarcinogenesis Cancers doi: 10.3390/cancers12010005 Authors: Csaba Hegedűs Gábor Boros Eszter Fidrus Gréta Nikoletta Kis Miklós Antal Tamás Juhász Eszter Anna Janka Laura Jankó György Paragh Gabriella Emri Péter Bai Éva Remenyik Keratinocytes provide the first line of defense of the human body against carcinogenic ultraviolet...
Wed Dec 18, 2019 02:00
Cancers, Vol. 12, Pages 6: Hypertonicity-Affected Genes Are Differentially Expressed in Clear Cell Renal Cell Carcinoma and Correlate with Cancer-Specific Survival Cancers doi: 10.3390/cancers12010006 Authors: Kandabarau Leiz Krohn Winter Bedke Schwab Schaeffeler Edemir The heterogeneity of renal cell carcinoma (RCC) subtypes reflects the cell type of origin in the nephron, with consequences for therapy and prognosis. The transcriptional cues that determine...
Wed Dec 18, 2019 02:00
Cancers, Vol. 12, Pages 4: Recent Progress in Mitochondria-Targeted Drug and Drug-Free Agents for Cancer Therapy Cancers doi: 10.3390/cancers12010004 Authors: Jeena Kim Jin Ryu The mitochondrion is a dynamic eukaryotic organelle that controls lethal and vital functions of the cell. Being a critical center of metabolic activities and involved in many diseases, mitochondria have been attracting attention as a potential target for therapeutics, especially for cancer treatment....
Wed Dec 18, 2019 02:00
Cancers, Vol. 12, Pages 3: Upregulation of ZIP14 and Altered Zinc Homeostasis in Muscles in Pancreatic Cancer Cachexia Cancers doi: 10.3390/cancers12010003 Authors: Ahmad Rushdi Shakri Timothy James Zhong Wanchao Ma Courtney Coker Sean Kim Stephanie Calluori Hanna Scholze Matthias Szabolcs Thomas Caffrey Paul M. Grandgenett Michael A. Hollingsworth Kurenai Tanji Michael D. Kluger George Miller Anup Kumar Biswas Swarnali Acharyya Pancreatic...
Wed Dec 18, 2019 02:00
Cancers, Vol. 12, Pages 2: Metabolic Alterations in Pancreatic Cancer Progression Cancers doi: 10.3390/cancers12010002 Authors: Enza Vernucci Jaime Abrego Venugopal Gunda Surendra K. Shukla Aneesha Dasgupta Vikrant Rai Nina Chaika Kyla Buettner Alysha Illies Fang Yu Audrey J. Lazenby Benjamin J. Swanson Pankaj K. Singh Pancreatic cancer is the third leading cause of cancer-related deaths in the USA. Pancreatic tumors are characterized by enhanced glycolytic...
Wed Dec 18, 2019 02:00
Cancers, Vol. 12, Pages 1: A Novel Gene Signature-Based Model Predicts Biochemical Recurrence-Free Survival in Prostate Cancer Patients after Radical Prostatectomy Cancers doi: 10.3390/cancers12010001 Authors: Shi Bao Weischenfeldt Schaefer Rogowski Schmidt-Hegemann Unger Lauber Wang Buchner Stief Schlomm Belka Li Abstract: Currently, decision-making regarding biochemical recurrence (BCR) following prostatectomy relies solely on clinical...
Wed Dec 18, 2019 02:00
Cells, Vol. 9, Pages 20: Lights and Shadows in the Use of Mesenchymal Stem Cells in Lung Inflammation, a Poorly Investigated Topic in Cystic Fibrosis Cells doi: 10.3390/cells9010020 Authors: Caretti Peli Colombo Zulueta Mesenchymal stem cells (MSCs) are multipotent non-hematopoietic stem cells residing in many tissues, including the lung. MSCs have long been regarded as a promising tool for cell-based therapy because of their ability to replace damaged tissue by differentiating...
Thu Dec 19, 2019 02:00
Cells, Vol. 9, Pages 21: Brain-Derived Extracellular Vesicle microRNA Signatures Associated with In Utero and Postnatal Oxycodone Exposure Cells doi: 10.3390/cells9010021 Authors: Shahjin Guda Schaal Odegaard Clark Gowen Xiao Lisco Pendyala Yelamanchili Oxycodone (oxy) is a semi-synthetic opioid commonly used as a pain medication that is also a widely abused prescription drug. While very limited studies have examined the effect of in utero oxy (IUO)...
Thu Dec 19, 2019 02:00
Cells, Vol. 9, Pages 22: Peroxiredoxin 5 Silencing Sensitizes Dopaminergic Neuronal Cells to Rotenone via DNA Damage-Triggered ATM/p53/PUMA Signaling-Mediated Apoptosis Cells doi: 10.3390/cells9010022 Authors: Wang Huang Chiu Chang Wu Peroxiredoxins (Prxs) are a family of thioredoxin peroxidases. Accumulating evidence suggests that changes in the expression of Prxs may be involved in neurodegenerative diseases pathology. However, the expression and function of Prxs in...
Thu Dec 19, 2019 02:00
Cells, Vol. 9, Pages 23: Functional Compartmentalization of HSP60-Survivin Interaction between Mitochondria and Cytosol in Cancer Cells Cells doi: 10.3390/cells9010023 Authors: Huang Yeh Heat shock protein 60 (HSP60) and survivin reside in both the cytosolic and mitochondrial compartments under physiological conditions. They can form HSP60-survivin complexes through protein–protein interactions. Their expression levels in cancer tissues are positively correlated and higher...
Thu Dec 19, 2019 02:00
Cells, Vol. 9, Pages 19: Serine-Arginine Protein Kinase 1 (SRPK1) as a Prognostic Factor and Potential Therapeutic Target in Cancer: Current Evidence and Future Perspectives Cells doi: 10.3390/cells9010019 Authors: Nikas Themistocleous Paschou Tsamis Ryu Cancer, a heterogeneous disease composed of tumor cells and microenvironment, is driven by deregulated processes such as increased proliferation, invasion, metastasis, angiogenesis, and evasion of apoptosis. Alternative...
Thu Dec 19, 2019 02:00
Cells, Vol. 9, Pages 18: Phosphoenolpyruvate from Glycolysis and PEPCK Regulate Cancer Cell Fate by Altering Cytosolic Ca2+ Cells doi: 10.3390/cells9010018 Authors: Moreno-Felici Hyroššová Aragó Rodríguez-Arévalo García-Rovés Escolano Perales Changes in phosphoenolpyruvate (PEP) concentrations secondary to variations in glucose availability can regulate calcium signaling in T cells as this metabolite potently inhibits the sarcoplasmic reticulum Ca2+/ATPase pump...
Thu Dec 19, 2019 02:00
Cells, Vol. 9, Pages 17: Mitochondrial Gene Expression and Beyond—Novel Aspects of Cellular Physiology Cells doi: 10.3390/cells9010017 Authors: Kotrys Szczesny Mitochondria are peculiar organelles whose proper function depends on the crosstalk between two genomes, mitochondrial and nuclear. The human mitochondrial genome (mtDNA) encodes only 13 proteins; nevertheless, its proper expression is essential for cellular homeostasis, as mtDNA-encoded proteins are constituents of mitochondrial...
Thu Dec 19, 2019 02:00
Cells, Vol. 9, Pages 15: Multiple Sclerosis CD49d+CD154+ As Myelin-Specific Lymphocytes Induced During Remyelination Cells doi: 10.3390/cells9010015 Authors: Piatek Namiecinska Domowicz Wieczorek Michlewska Matysiak Lewkowicz Tarkowski Lewkowicz Multiple sclerosis (MS) is a demyelinating autoimmune disease of the central nervous system (CNS) mediated by autoreactive lymphocytes. The role of autoreactive lymphocytes in the CNS demyelination is well described,...
Thu Dec 19, 2019 02:00
Cells, Vol. 9, Pages 16: Identification of Astrocytoma Blood Serum Protein Profile Cells doi: 10.3390/cells9010016 Authors: Vaitkiene Urbanaviciute Grigas Steponaitis Tamasauskas Skiriutė High-grade astrocytomas are some of the most common and aggressive brain cancers, whose signs and symptoms are initially non-specific. Up to the present date, there are no diagnostic tools to observe the early onset of the disease. Here, we analyzed the combination of blood serum...
Thu Dec 19, 2019 02:00
Cells, Vol. 9, Pages 13: Perturbation of Nuclear Hormone Receptors by Endocrine Disrupting Chemicals: Mechanisms and Pathological Consequences of Exposure Cells doi: 10.3390/cells9010013 Authors: Hall Greco Much of the early work on Nuclear Hormone Receptors (NHRs) focused on their essential roles as mediators of sex steroid hormone signaling in reproductive development and function, and thyroid hormone-dependent formation of the central nervous system. However, as NHRs display...
Thu Dec 19, 2019 02:00
Cells, Vol. 9, Pages 14: Single-Cell Expression Variability Implies Cell Function Cells doi: 10.3390/cells9010014 Authors: Daniel Osorio Xue Yu Yan Zhong Guanxun Li Peng Yu Erchin Serpedin Jianhua Z. Huang James J. Cai As single-cell RNA sequencing (scRNA-seq) data becomes widely available, cell-to-cell variability in gene expression, or single-cell expression variability (scEV), has been increasingly appreciated. However, it remains unclear whether this variability...
Thu Dec 19, 2019 02:00
Cells, Vol. 9, Pages 12: Genetic Associations with Aging Muscle: A Systematic Review Cells doi: 10.3390/cells9010012 Authors: Pratt Boreham Ennis Ryan De Vito The age-related decline in skeletal muscle mass, strength and function known as ‘sarcopenia’ is associated with multiple adverse health outcomes, including cardiovascular disease, stroke, functional disability and mortality. While skeletal muscle properties are known to be highly heritable,...
Thu Dec 19, 2019 02:00
Cells, Vol. 9, Pages 11: Inhibition of the IL-18 Receptor Signaling Pathway Ameliorates Disease in a Murine Model of Rheumatoid Arthritis Cells doi: 10.3390/cells9010011 Authors: Nozaki Ri Sakai Niki Kinoshita Funauchi Matsumura Interleukin (IL)-18 expression in synovial tissue correlates with the severity of joint inflammation and the levels of pro-inflammatory cytokines. However, the role of the IL-18/IL-18 receptor-alpha (Rα) signaling pathway in...
Wed Dec 18, 2019 02:00
Cells, Vol. 9, Pages 9: Engineered Maturation Approaches of Human Pluripotent Stem Cell-Derived Ventricular Cardiomyocytes Cells doi: 10.3390/cells9010009 Authors: Ge Wang Xi Heart diseases such as myocardial infarction and myocardial ischemia are paroxysmal and fatal in clinical practice. Cardiomyocytes (CMs) differentiated from human pluripotent stem cells provide a promising approach to myocardium regeneration therapy. Identifying the maturity level of human pluripotent stem...
Wed Dec 18, 2019 02:00
Cells, Vol. 9, Pages 10: Splicing Dysregulation as Oncogenic Driver and Passenger Factor in Brain Tumors Cells doi: 10.3390/cells9010010 Authors: Pamela Bielli Vittoria Pagliarini Marco Pieraccioli Cinzia Caggiano Claudio Sette Brain tumors are a heterogeneous group of neoplasms ranging from almost benign to highly aggressive phenotypes. The malignancy of these tumors mostly relies on gene expression reprogramming, which is frequently accompanied by the aberrant regulation...
Wed Dec 18, 2019 02:00
Cells, Vol. 9, Pages 8: microRNA: The Impact on Cancer Stemness and Therapeutic Resistance Cells doi: 10.3390/cells9010008 Authors: Jiao Qian Wu Li Wang Kong Xiong Cancer ranks as the second leading cause of death worldwide, causing a large social and economic burden. However, most anti-cancer treatments face the problems of tumor recurrence and metastasis. Therefore, finding an effective cure for cancer needs to be solved urgently. Recently, the discovery of...
Wed Dec 18, 2019 02:00
Cells, Vol. 9, Pages 6: TIMP-1 is Overexpressed and Secreted by Platinum Resistant Epithelial Ovarian Cancer Cells Cells doi: 10.3390/cells9010006 Authors: Sonego Poletto Pivetta Nicoloso Pellicani Vinciguerra Citron Sorio Mongiat Baldassarre Epithelial Ovarian Cancer (EOC) is the most lethal gynecological cancer in developed countries, and the development of new strategies to overcome chemoresistance is an awaited clinical need. Angiogenesis, the...
Wed Dec 18, 2019 02:00
Cells, Vol. 9, Pages 5: Metabolic Reprogramming in Mitochondria of Myeloid Cells Cells doi: 10.3390/cells9010005 Authors: Hao Zuo Yihong Wan The myeloid lineage consists of multiple immune cell types, such as macrophages, monocytes, and dendritic cells. It actively participates in both innate and adaptive immunity. In response to pro- or anti-inflammatory signals, these cells undergo distinct programmed metabolic changes especially in mitochondria. Pro-inflammatory signals induce...
Wed Dec 18, 2019 02:00
Cells, Vol. 9, Pages 7: Disruption of Cancer Metabolic SREBP1/miR-142-5p Suppresses Epithelial–Mesenchymal Transition and Stemness in Esophageal Carcinoma Cells doi: 10.3390/cells9010007 Authors: Huang Huang Hsu Huang Fong Lee Liu : Elevated activity of sterol regulatory element-binding protein 1 (SREBP1) has been implicated in the tumorigenesis of different cancer types. However, the functional roles of SREBP1 in esophageal cancer are not well appreciated. Here,...
Wed Dec 18, 2019 02:00
Cells, Vol. 9, Pages 4: Albumin Modifies Responses to Hematopoietic Stem Cell Mobilizing Agents in Mice Cells doi: 10.3390/cells9010004 Authors: Danner Bonig Wiercinska Albumin, the most abundant plasma protein, not only controls osmotic blood pressure, but also serves as a carrier for various small molecules, including pharmaceuticals. Its impact on pharmacological properties of many drugs has been extensively studied over decades. Here, we focus on its interaction with the...
Wed Dec 18, 2019 02:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου