Molecular Medicine - Volume:44 Number: Spandidos Publications

O-GlcNAcylation in immunity and inflammation: An intricate system (Review)

Yu Li, Mingzheng Xie, Lili Men, Jianling Du

View Abstract ❯

The association of female and male infertility with telomere length (Review) Eleni Vasilopoulos, Persefoni Fragkiadaki, Charikleia Kalliora, Domniki Fragou, Anca Oana Docea, Elena Vakonaki, Dimitris Tsoukalas, Daniela Calina, Ana Maria Buga, George Georgiadis, Charalampos Mamoulakis, Antonios Makrigiannakis, Demetrios A. Spandidos, Aristidis Tsatsakis View Abstract ❯

Screening of differentially expressed genes and identification of NUF2 as a prognostic marker in breast cancer Wenjie Xu, Yizhen Wang, Yanan Wang, Shanmei Lv, Xiuping Xu, Xuejun Dong View Abstract ❯

Hydroxysafflor Yellow A mitigated myocardial ischemia/reperfusion injury by inhibiting the activation of the JAK2/STAT1 pathway Donglai Zhou, Tingting Ding, Bin Ni, Yunyan Jing, Shanxin Liu View Abstract ❯

Role of TXNIP/NLRP3 in sepsis-induced myocardial dysfunction Chun Yang, Wan Xia, Xiaolin Liu, Jian Lin, Aiping Wu View Abstract ❯

HMGA2 regulates acute myeloid leukemia progression and sensitivity to daunorubicin via Wnt/β-catenin signaling Shuo Yang, Yueli Gu, Genjie Wang, Qingzhu Hu, Shuxia Chen, Yong Wang, Mingfeng Zhao View Abstract ❯

Quinalizarin, a specific CK2 inhibitor, can reduce icotinib resistance in human lung adenocarcinoma cell lines Ke Li, Fangzheng Zhou, Yu Zhou, Sheng Zhang, Qianwen Li, Zhenyu Li, Li Liu, Gang Wu, Rui Meng View Abstract ❯

Effects of transcription factor EB on oxidative stress and apoptosis induced by high glucose in podocytes Yingli Kang, Ying Li, Tao Zhang, Yanqing Chi, Maodong Liu View Abstract ❯

Protective effects of salvianolic acid B against hydrogen peroxide‑induced apoptosis of human umbilical vein endothelial cells and underlying mechanisms Shan Gao, Shiqin Li, Qin Li, Fuyong Zhang, Mengqi Sun, Zilin Wan, Shurong Wang View Abstract ❯

Erythropoietin suppresses hepatic steatosis and obesity by inhibiting endoplasmic reticulum stress and upregulating fibroblast growth factor 21 Ting Hong, Zhijuan Ge, Bingjie Zhang, Ran Meng, Dalong Zhu, Yan Bi View Abstract ❯

Sevoflurane alleviates LPS‑induced acute lung injury via the microRNA‑27a‑3p/TLR4/MyD88/NF‑κB signaling pathway Yunfei Wang, Xiaoran Zhang, Jianmin Tian, Guoze Liu, Xiaofang Li, Dan Shen View Abstract ❯

Rap1 regulates hepatic stellate cell migration through the modulation of RhoA activity in response to TGF‑β1 Mi‑Young Moon, Hee‑Jun Kim, Mo‑Jong Kim, Sunho Uhm, Ji‑Won Park, Ki‑Tae Suk, Jae‑Bong Park, Dong‑Jun Kim, Sung‑Eun Kim View Abstract ❯

Tetramethylpyrazine protects retinal ganglion cells against H2O2‑induced damage via the microRNA‑182/mitochondrial pathway Xinmin Li, Qiuli Wang, Yanfan Ren, Xiaomin Wang, Huaxu Cheng, Hua Yang, Baojun Wang View Abstract ❯

Molecular characterization of alterations in the intestinal microbiota of patients with grade 3 hypertension Nosheen Mushtaq, Safdar Hussain, Siruo Zhang, Lu Yuan, Huan Li, Shakir Ullah, Yan Wang, Jiru Xu View Abstract ❯

T7 peptide cytotoxicity in human hepatocellular carcinoma cells is mediated by suppression of autophagy Feng Liu, Fuhai Wang, Xiaofeng Dong, Peng Xiu, Pengfei Sun, Zhongchao Li, Xuetao Shi, Jingtao Zhong View Abstract ❯

Investigating the regulatory role of ORMDL3 in airway barrier dysfunction using in vivo and in vitro models Ruixue Yang, Min Tan, Jianya Xu, Xia Zhao View Abstract ❯

Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway Rui Yang, Qiang Jia, Shan‑Feng Ma, Ya Wang, Shomaila Mehmood, Yan Chen View Abstract ❯

Anti‑photoaging effect of fermented agricultural by‑products on ultraviolet B‑irradiated hairless mouse skin Sun‑Il Choi, Tae‑Dong Jung, Bong‑Yeon Cho, Seung‑Hyun Choi, Wan‑Sup Sim, Xionggao Han, Sang Jong Lee, Young‑Cheul Kim, Ok‑Hwan Lee View Abstract ❯

MicroRNA-141 ameliorates alcoholic hepatitis‑induced intestinal injury and intestinal endotoxemia partially via a TLR4-dependent mechanism Wei‑He Qian, Yuan‑Yuan Liu, Xiang Li, Yan Pan View Abstract ❯

Zoledronic acid inhibits osteoclast differentiation and function through the regulation of NF-κB and JNK signalling pathways Xiao‑Lin Huang, Lie‑Yu Huang, Yu‑Ting Cheng, Fang Li, Qian Zhou, Chao Wu, Qian‑Hui Shi, Zhi‑Zhong Guan, Jian Liao, Wei Hong View Abstract ❯

miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian View Abstract ❯

A microRNA‑24‑to‑secretagogin regulatory pathway mediates cholesterol‑induced inhibition of insulin secretion Jing Yang, Yuncheng Lv, Zhibo Zhao, Wu Li, Sunmin Xiang, Lingzhi Zhou, Anbo Gao, Bin Yan, Lingling Ou, Hong Ling, Xinhua Xiao, Jianghua Liu View Abstract ❯

Classical dendritic cells regulate acute lung inflammation and injury in mice with lipopolysaccharide‑induced acute respiratory distress syndrome Lang Li, Liang Dong, Dan Zhao, Fei Gao, Jie Yan View Abstract ❯

Long non-coding RNA XIST promotes extracellular matrix degradation by functioning as a competing endogenous RNA of miR-1277-5p in osteoarthritis Tao Wang, Yize Liu, Yong Wang, Xuyang Huang, Wei Zhao, Zhonghai Zhao View Abstract ❯

Effects of miR‑340 overexpression and knockdown on the proliferation and metastasis of NSCLC cell lines Xidan Zhu, Gang Tian, Jing Quan, Peng He, Jinbo Liu View Abstract ❯

Strontium promotes osteogenic differentiation by activating autophagy via the the AMPK/mTOR signaling pathway in MC3T3‑E1 cells You Cheng, Lunhui Huang, Yichao Wang, Qianyu Huo, Yanhong Shao, Huijing Bao, Zhaoyang Li, Yunde Liu, Xue Li View Abstract ❯

Botulinum toxin type A prevents the phenotypic transformation of fibroblasts induced by TGF‑β1 via the PTEN/PI3K/Akt signaling pathway Xue Zhang, Dong Lan, Shuhua Ning, Hongxia Jia, Sisi Yu View Abstract ❯

Curcumin‑loaded PEG‑PDLLA nanoparticles for attenuating palmitate‑induced oxidative stress and cardiomyocyte apoptosis through AMPK pathway Jingyi Zhang, Ying Wang, Cuiyu Bao, Tao Liu, Shuai Li, Jiaxi Huang, Ying Wan, Jing Li View Abstract ❯

Celecoxib inhibits the epithelial-to-mesenchymal transition in bladder cancer via the miRNA-145/TGFBR2/Smad3 axis Xiaoqiang Liu, Yanlong Wu, Zhengtao Zhou, Mingchuan Huang, Wen Deng, Yibing Wang, Xiaochen Zhou, Luyao Chen, Yu Li, Tao Zeng, Gongxian Wang, Bin Fu View Abstract ❯

miR‑128 is upregulated in epilepsy and promotes apoptosis through the SIRT1 cascade De‑Zhe Chen, Wei‑Wei Wang, Yan‑Ling Chen, Xia‑Feng Yang, Min Zhao, Yan‑Yan Yang View Abstract ❯

Excess fructose and fatty acids trigger a model of non‑alcoholic fatty liver disease progression in vitro: Protective effect of the flavonoid silybin Elena Grasselli, Francesca Baldini, Giulia Vecchione, Paulo J. Oliveira, Vilma A. Sardão, Adriana Voci, Piero Portincasa, Laura Vergani View Abstract ❯

Structural characterization and immune regulation of a novel polysaccharide from Maerkang Lactarius deliciosus Gray Siyuan Su, Xiang Ding, Lei Fu, Yiling Hou View Abstract ❯

Protective effect of nicorandil on collapse‑induced lung injury in rabbits by inhibiting apoptosis Chunguang Wang, Honggang Ke, Xingguo Xu, Junjie Chen, Dongyun Sun, Fuhai Ji View Abstract ❯

Resveratrol‑loaded nanoparticles inhibit enterovirus 71 replication through the oxidative stress‑mediated ERS/autophagy pathway Na Du, Xiao‑Hua Li, Wan‑Guo Bao, Bin Wang, Guang Xu, Feng Wang View Abstract ❯

Autophagy protects nucleus pulposus cells from cyclic mechanical tension‑induced apoptosis Minghui Yang, Chencheng Feng, Yang Zhang, Chang Liu, Bin Li, Qi Zhu, Bo Huang, Yue Zhou View Abstract ❯

Enterovirus 71 VP1 promotes mouse Schwann cell autophagy via ER stress‑mediated PMP22 upregulation Peiqing Li, Sida Yang, Dandan Hu, Dan Wei, Jing Lu, Huanying Zheng, Shushan Nie, Guangming Liu, Haomei Yang View Abstract ❯

[Corrigendum] Analysis of a nanoparticle‑enriched fraction of plasma reveals miRNA candidates for Down syndrome pathogenesis Alessandro Salvi, Marika Vezzoli, Sara Busatto, Lucia Paolini, Teresa Faranda, Edoardo Abeni, Maria Caracausi, Francesca Antonaros, Allison Piovesan, Chiara Locatelli, Guido Cocchi, Gualtiero Alvisi, Giuseppina De Petro, Doris Ricotta, Paolo Bergese, Annalisa Radeghieri View Abstract ❯

RIP1/RIP3-regulated necroptosis as a target for multifaceted disease therapy (Review) Yuping Liu, Ting Liu, Tiantian Lei, Dingding Zhang, Suya Du, Lea Girani, Dandan Qi, Chen Lin, Rongsheng Tong, Yi Wang View Abstract ❯

Construction of prognostic risk prediction model of oral squamous cell carcinoma based on co-methylated genes Qiang Zhu , Gang Tian, Jianyong Gao View Abstract ❯

Epigenetic regulation of COX‑2 expression by DNA hypomethylation via NF‑κB activation in ketamine‑induced ulcerative cystitis Shu‑Mien Chuang, Jian‑He Lu, Kun‑Ling Lin, Cheng‑Yu Long, Yung‑Chin Lee, Hui‑Pin Hsiao, Chia‑Chun Tsai, Wen‑Jeng Wu, Hui‑Jun Yang, Yung‑Shun Juan View Abstract ❯

Effect of HMGB1 and RAGE on brain injury and the protective mechanism of glycyrrhizin in intracranial‑sinus occlusion followed by mechanical thrombectomy recanalization Shu‑Wen Mu, Yuan Dang, Ya‑Cao Fan, Hao Zhang, Jian‑He Zhang, Wei Wang, Shou‑Sen Wang, Jian‑Jun Gu View Abstract ❯

Time-dependent C5a and C5aR expression in dental pulp cells following stimulation with LTA and LPS Mingyue Liu, Haibin Mu, Wenting Peng, Lin Zhao, Weiping Hu, Zhuling Jiang, Li Gao, Xiaofang Cao, Ning Li, Jingying Han View Abstract ❯

Altered expression of itch‑related mediators in the lower cervical spinal cord in mouse models of two types of chronic itch Bao‑Wen Liu, Zhi‑Xiao Li, Zhi‑Gang He, Qian Wang, Cheng Liu, Xian‑Wei Zhang, Hui Yang, Hong‑Bing Xiang View Abstract ❯

Astragaloside IV inhibits oxidized low‑density lipoprotein‑induced endothelial damage via upregulation of miR‑140‑3p Weibin Qian, Qiuhai Qian, Xinrui Cai, Ru Han, Wenjun Yang, Xinyue Zhang, Hongmin Zhao, Ranran Zhu View Abstract ❯

The role of antimiR-26a-5p/biphasic calcium phosphate in repairing rat femoral defects Xiaoyan Yuan, Lu Han, Hai Lin, Zeyou Guo, Yanling Huang, Shasha Li, Ting Long, Wei Tang, Weidong Tian, Jie Long View Abstract ❯

Long non‑coding RNA MALAT1 sponges miR‑124‑3p.1/KLF5 to promote pulmonary vascular remodeling and cell cycle progression of pulmonary artery hypertension Dapeng Wang, Hongyang Xu, Bo Wu, Shuyun Jiang, Hong Pan, Ruilan Wang, Jingyu Chen View Abstract ❯

HMGB1 enhances mechanical stress-induced cardiomyocyte hypertrophy in vitro via the RAGE/ERK1/2 signaling pathway Lei Zhang, Xue Yang, Guoliang Jiang, Ying Yu, Jian Wu, Yangang Su, Aijun Sun, Yunzeng Zou, Hong Jiang, Junbo Ge View Abstract ❯

Quercetin protects against atherosclerosis by regulating the expression of PCSK9, CD36, PPARγ, LXRα and ABCA1 Qingling Jia, Hui Cao, Dingzhu Shen, Shanshan Li, Li Yan, Chuan Chen, Sanli Xing, Fangfang Dou View Abstract ❯

Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du View Abstract ❯

Leonurus sibiricus L. ethanol extract promotes osteoblast differentiation and inhibits osteoclast formation Jae‑Hyun Kim, Minsun Kim, Hyuk‑Sang Jung, Youngjoo Sohn View Abstract ❯

Effects of high glucose on proliferation and function of circulating fibrocytes: Involvement of CXCR4/SDF‑1 axis Yingzheng Weng, Jiangjie Lou, Xiaowei Liu, Senna Lin, Chenkai Xu, Changqing Du, Lijiang Tang View Abstract ❯

Expression changes of CX3CL1 and CX3CR1 proteins in the hippocampal CA1 field of the gerbil following transient global cerebral ischemia Ji Hyeon Ahn, Dae Won Kim, Joon Ha Park, Tae‑Kyeong Lee, Hyang‑Ah Lee, Moo‑Ho Won, Choong‑Hyun Lee View Abstract ❯

Pistacia weinmannifolia ameliorates cigarette smoke and lipopolysaccharide‑induced pulmonary inflammation by inhibiting interleukin‑8 production and NF‑κB activation Jae‑Won Lee, Hyung Won Ryu, Su Ui Lee, Min‑Gu Kim, Ok‑Kyoung Kwon, Mun Ok Kim, Tae Kyu Oh, Jae Kyoung Lee, Tae Young Kim, Sang Woo Lee, Sangho Choi, Wan‑Yi Li, Kyung‑Seop Ahn, Sei‑Ryang Oh View Abstract ❯

Micro‑dimpled surface atelocollagen maintains primary human hepatocytes in culture and may promote their functionality compared with collagen coat culture Tetsuro Sato, Kayoko Semura, Ichiro Fujimoto View Abstract ❯

miR-92a-3p promotes the proliferation, migration and invasion of esophageal squamous cell cancer by regulating PTEN Xin Li, Shuilong Guo, Li Min, Qingdong Guo, Shutian Zhang View Abstract ❯

Gas6 attenuates lipopolysaccharide‑induced TNF‑α expression and apoptosis in H9C2 cells through NF‑κB and MAPK inhibition via the Axl/PI3K/Akt pathway Mengfang Li, Jingjing Ye, Guangju Zhao, Guangliang Hong, Xiyi Hu, Kaiqiang Cao, You Wu, Zhongqiu Lu View Abstract ❯

SIRT1 activation alleviates brain microvascular endothelial dysfunction in peroxisomal disorders Yunshan Zhang, Guiyun Cui, Yue Wang, Yi Gong, Yulan Wang View Abstract ❯

Comparison of the therapeutic effects of adipose‑derived and bone marrow mesenchymal stem cells on erectile dysfunction in diabetic rats Sansan Chen, Jianbin Zhu, Mingzhu Wang, Yanting Huang, Zhuolin Qiu, Jingjing Li, Xinglu Chen, Huiying Chen, Mingyu Xu, Jun Liu, Miaoqin She, Hongwei Li, Xiaorong Yang, Yi Wang, Xiangsheng Cai View Abstract ❯

Identification of long non‑coding RNA‑mediated transcriptional dysregulation triplets reveals global patterns and prognostic biomarkers for ER+/PR+, HER2‑ and triple negative breast cancer Zhengwei Du, Wei Gao, Jiayi Sun, Yujing Li, Yu Sun, Tong Chen, Shuke Ge, Wenbin Guo View Abstract ❯

Alantolactone enhances gemcitabine sensitivity of lung cancer cells through the reactive oxygen species-mediated endoplasmic reticulum stress and Akt/GSK3β pathway Jiquan Wang, Yingbing Zhang, Xu Liu, Jizhao Wang, Bin Li, Yongkang Liu, Jiansheng Wang View Abstract ❯

Downregulated miR‑302d‑3p promotes chondrocyte proliferation and migration by regulation of Unc‑51‑like kinase 1 Shangzeng Wang, Yongzhi Zheng, Zheng Hu, Zhen Wang, Yingjie Zhang, Licheng Wei View Abstract ❯

Hydrogen-rich saline alleviates inflammation and apoptosis in myocardial I/R injury via PINK-mediated autophagy Li Yao, Hongguang Chen, Qinghua Wu, Keliang Xie View Abstract ❯

Circular RNA profile in liver tissue of EpCAM knockout mice Yanhong Yang, Shaomin Liu, Zili Lei, Guibin Chen, Li Huang, Fei Yang, Yuting Lei, Yanyan Liu, Lanxiang Yang, Wanwan Liu, Liangxue Lai, Jiao Guo View Abstract ❯

Hypertonic saline downregulates endothelial cell-derived VEGF expression and reduces blood-brain barrier permeability induced by cerebral ischaemia via the VEGFR2/eNOS pathway Qiaosheng Wang, Yiyu Deng, Linqiang Huang, Wenxin Zeng, Shenglong Chen, Bo Lv, Wenqiang Jiang, Yongli Han, Hongguang Ding, Miaoyun Wen, Hongke Zeng View Abstract ❯

Increased expression of Sonic hedgehog restores diabetic endothelial progenitor cells and improves cardiac repair after acute myocardial infarction in diabetic mice Qing Xiao, Xiao‑Ya Zhao, Ru‑Chao Jiang, Xiu‑Hui Chen, Xiang Zhu, Kai‑Feng Chen, Sheng‑Ying Chen, Xiao‑Ling Zhang, Yuan Qin, Ying‑Hua Liu, Jian‑Dong Luo View Abstract ❯

Complex TNF-α B cell epitope MAP vaccine alleviates murine ulcerative colitis Yan Sun, Wensheng Pan, Jun Zhang, Ying Cui, Huiju Wang, Guoqing Ru, Legao Chen View Abstract ❯

CaSR activates PKCδ to induce cardiomyocyte apoptosis via ER stress‑associated apoptotic pathways during ischemia/reperfusion Chong Liu, Huanming Li, Huishuang Zheng, Meili Zhai, Fanghao Lu, Shiyun Dong, Tao Fang, Weihua Zhang View Abstract ❯

Alcohol‑induced attenuation of post‑traumatic inflammation is not necessarily liver‑protective following trauma/hemorrhage Nils Wagner, Scott Dieteren, Niklas Franz, Kernt Köhler, Mario Perl, Ingo Marzi, Borna Relja View Abstract ❯

Downregulation of microRNA‑629‑5p in colorectal cancer and prevention of the malignant phenotype by direct targeting of low‑density lipoprotein receptor‑related protein 6 Guoqiang Yan, Chenyao Li, Yuhang Zhao, Meng Yue, Lei Wang View Abstract ❯

Biologically active 1,25-dihydroxyvitamin D3 protects against experimental sepsis by negatively regulating the Toll-like receptor 4/myeloid differentiation primary response gene 88/Toll-IL-1 resistance-domain-containing adapter-inducing interferon-β signaling pathway Ge Zheng, Na Wen, Minli Pan, Yumao Huang, Zhishu Li View Abstract ❯

GLP‑1 improves palmitate‑induced insulin resistance in human skeletal muscle via SIRT1 activity Ja Young Jeon, Sung‑E Choi, Eun Suk Ha, Han Byeol Lee, Tae Ho Kim, Seung Jin Han, Hae Jin Kim, Dae Jung Kim, Yup Kang, Kwan‑Woo Lee View Abstract ❯

MicroRNA-592 suppresses the malignant phenotypes of thyroid cancer by regulating lncRNA NEAT1 and downregulating NOVA1 Yiqiang Luo, Tianwei Hao, Jian Zhang, Ming Zhang, Peng Sun, Lei Wu View Abstract ❯

[Corrigendum] Alterations in gene expression during sexual differentiation in androgen receptor knockout mice induced by environmental endocrine disruptors Dehong Liu, Liping Shen, Yonglin Tao, Ying Kuang, Lei Cai, Dan Wang, Meiduo He, Xuebo Tong, Shuguang Zhou, Jie Sun, Chenchen Shi, Chunxiao Wang, Yi Wu View Abstract ❯

10-12 October, 2019, Mystras Grand Palace Resort, Sparta, Greece 24nd World Congress on Advances in Oncology & 24th International Symposium on Molecular Medicine 8-9 October 2019, Pre-Congress Workshop: 'SNP genotyping and rare mutation detection in cancer with molecular methods'

7-9 May, 2020, Grand Hotel, Duca D'Este, Rome, Italy 26th International Symposium on Molecular Medicine