Toppling the Ethical Balance — Health Care Refusal and the Trump Administration E. Sepper DOI: 10.1056/NEJMp1908839 | July 31, 2019 Population and the Environment — Time for Another Contraception Revolution D.J. Anderson N Engl J Med 2019;381:397-399 Saving the Endangered Physician-Scientist — A Plan for Accelerating Medical Breakthroughs M.K. Jain and Others N Engl J Med 2019;381:399-402 Ghosts of Our Collective Subconscious — What Blackface in a Yearbook Photo Means for Medical Education D.W. Paul, Jr. N Engl J Med 2019;381:402-403 “Browner” — Creating Narratives of Race T. Vijayan N Engl J Med 2019;381:404-405 ORIGINAL ARTICLES Immediate Transfusion in African Children with Uncomplicated Severe Anemia K. Maitland and Others N Engl J Med 2019;381:407-419 Transfusion Volume for Children with Severe Anemia in Africa K. Maitland and Others N Engl J Med 2019;381:420-431 Ibrutinib–Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia T.D. Shanafelt and Others N Engl J Med 2019;381:432-443 Immunogenicity of Fractional-Dose Vaccine during a Yellow Fever Outbreak — Final Report R.M. Casey and Others N Engl J Med 2019;381:444-454 | Preliminary Report Published Online February 14, 2018 REVIEW ARTICLE Frontiers in Medicine: Gene Therapy K.A. High and M.G. Roncarolo N Engl J Med 2019;381:455-464 Image Challenge What’s the diagnosis? Additional Published Content

IMAGES IN CLINICAL MEDICINE Cutaneous Ulcerations in Anti-MDA5 Dermatomyositis A. Charrow and R.A. Vleugels N Engl J Med 2019;381:465 Obstructive Hydrocephalus D.R. Santiago-Dieppa and M.L. Levy N Engl J Med 2019;381:e10 CLINICAL PROBLEM-SOLVING A Diagnosis to Chew On R.H. Goldman and L. Weissmann N Engl J Med 2019;381:466-473 EDITORIAL Immediate Transfusion and Transfusion Volume in African Children with Severe Anemia J.R. Ingelfinger N Engl J Med 2019;381:475-476 CLINICAL IMPLICATIONS OF BASIC RESEARCH Predicting Tumor Response to PD-1 Blockade L. Ding and F. Chen N Engl J Med 2019;381:477-479 MEDICINE AND SOCIETY Digital Futures Past — The Long Arc of Big Data in Medicine J.A. Greene and A.S. Lea N Engl J Med 2019;381:480-485 CORRESPONDENCE Phenotype in an Infant with SOD1 Homozygous Truncating Mutation Published Online July 17, 2019 Thrombolysis up to 9 Hours after Onset of Stroke Magnetically Levitated Left Ventricular Assist Device How to Perform an Elliptical Excision of the Skin CORRECTION Physician Participation in Lethal Injection