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Τετάρτη 31 Ιουλίου 2019


  • Early Acid Suppression Therapy Exposure and Fracture in Young Children
    Laura MalchodiKari WagnerApryl SusiGregory GormanElizabeth Hisle-Gorman
    PPI use in infancy, alone or with H2RAs, is associated with fracture after 1 year of age.
  • Acellular Pertussis Vaccine Effectiveness Over Time
    Ousseny ZerboJoan BartlettKristin GoddardBruce FiremanEdwin LewisNicola P.Klein
    Compared with children fully DTaP vaccinated, unvaccinated and undervaccinated children were at a greater risk of pertussis. However, most pertussis cases occurred among age-appropriately vaccinated children.
  • Incidence of Herpes Zoster Among Children: 2003–2014
    Sheila WeinmannAllison L. NalewayPadma KoppoluRoger BaxterEdward A. BelongiaSimon J. HambidgeStephanie A. IrvingMichael L. JacksonNicola P. KleinBruno LewinElizabeth LilesMona MarinNing SmithEric WeintraubColleen Chun
    Using data from 6 health care organizations, we examined herpes zoster (HZ) incidence among children in the varicella vaccine era (2003–2014).
  • Implementing Evidence-Based Strategies to Improve HPV Vaccine Delivery
    Melissa B. GilkeyMichael J. ParksMarjorie A. MargolisAnnie-Laurie McReeJason V.Terk
    The experience of a large, not-for-profit health care system suggests that local adaptation may be effective in engaging physicians in HPV vaccine–related QI efforts.
  • Mental Health Problems and Initiation of E-cigarette and Combustible Cigarette Use
    Kira E. RiehmAndrea S. YoungKenneth A. FederNoa KrawczykKayla N. TormohlenLauren R. PacekRamin MojtabaiRosa M. Crum
    Data from a nationally representative sample of youth were used to explore associations between mental health problems and initiation of e-cigarette and combustible cigarette use.
  • A Prediction Model to Identify Febrile Infants ≤60 Days at Low Risk of Invasive Bacterial Infection
    Paul L. AronsonVeronika ShabanovaEugene D. ShapiroMarie E. WangLise E.NigrovicChristopher M. PruittAdrienne G. DePorreRianna C. LeazerSanyukta DesaiLaura F. SartoriRichard D. MarbleSahar N. RooholaminiRussell J. McCullohChristopher WollFran BalamuthElizabeth R. AlpernSamir S. ShahDerek J. WilliamsWhitney L. BrowningNipam ShahMark I. Neumanfor the Febrile Young Infant Research Collaborative
    In this multicenter case-control study, we derive and internally validate a highly sensitive score that identifies non–ill-appearing febrile infants at low probability of bacteremia and/or bacterial meningitis.
  • Prevalence, Risk Factors, and Outcomes of Bacteremic Pneumonia in Children
    Cristin Q. FritzKathryn M. EdwardsWesley H. SelfCarlos G. GrijalvaYuwei ZhuSandra R. ArnoldJonathan A. McCullersKrow AmpofoAndrew T. PaviaRichard G.WunderinkEvan J. AndersonAnna M. BramleySeema JainDerek J. Williams
    Using systematic, prospective blood culture collection in children admitted with CAP, this study identifies risk factors and characterizes outcomes associated with bacteremia.
  • Infant Deaths in Sitting Devices
    Peter LiawRachel Y. MoonAutumn HanJeffrey D. Colvin
    This study uses a nationwide data set to compare risk factors for sleep-related infant deaths occurring in sitting devices and in nonsitting devices.
  • Safety Interventions and Liquid Laundry Detergent Packet Exposures
    Christopher E. GawHenry A. SpillerMarcel J. CasavantThitphalak ChounthirathGary A. Smith
    Liquid laundry detergent packet exposures among children <6 years of age have decreased modestly since 2015, whereas exposures among older children and adults have continued to increase.
  • Hydroxyurea Use for Sickle Cell Disease Among Medicaid-Enrolled Children
    David C. BrousseauTroy RichardsonMatt HallAngela M. EllisonSamir S. ShahJean L.RaphaelDavid G. BundyStaci Arnold
    This population-based study of children with SCD assesses trends in hydroxyurea use and associated changes in ED visits and hospitalizations.
  • Patterns of Electrolyte Testing at Children’s Hospitals for Common Inpatient Diagnoses
    Michael J. TchouMatt HallSamir S. ShahDavid P. JohnsonAlan R. SchroederJames W.AntoonMarquita C. GeniesRicardo QuinonezChristopher W. MillerSnehal P. ShahPatrick W. Bradyfor the Pediatric Research in Inpatient Settings (PRIS) Network
    A retrospective cohort study revealed wide variation in electrolyte testing rates across hospitals, with strong hospital-level correlation across diagnoses.
  • Cervical Spine Injury Risk Factors in Children With Blunt Trauma
    Julie C. LeonardLorin R. BrowneFahd A. AhmadHamilton SchwartzMichaelWallendorfJeffrey R. LeonardE. Brooke LernerNathan Kuppermann
    In this multicenter, prospective observational study of 4091 children who experienced blunt trauma, we identified 14 risk factors for CSI.
  • Palivizumab and Long-term Outcomes in Cystic Fibrosis
    Aliza K. FinkGavin GraffCarrie L. ByingtonDeena R. LoefflerMargaret RosenfeldLisaSaiman
    In this study, we explore palivizumab’s potential benefits related to longer-term outcomes (lung function at age 7, first acquisition of Pseudomonas, and hospitalizations) in children with CF.
  • A 2017 US Reference for Singleton Birth Weight Percentiles Using Obstetric Estimates of Gestation
    Izzuddin M. ArisKen P. KleinmanMandy B. BelfortAnjali KaimalEmily Oken
    This study provides an updated birth weight reference by using a more reliable GA estimate and reflects the current sociodemographic composition of the United States.
  • A Simpler Prediction Rule for Rebound Hyperbilirubinemia
    Pearl W. ChangThomas B. Newman
    We turned our previous 3-variable clinical prediction rule for rebound hyperbilirubinemia into a simpler 2-variable rule with similarly excellent discrimination.
  • Physical Activity and Trajectories of Cardiovascular Health Indicators During Early Childhood
    Nicole A. ProudfootSara King-DowlingJohn CairneySteven R. BrayMaureen J.MacDonaldBrian W. Timmons
    This prospective cohort study examines the longitudinal effects of physical activity on cardiovascular fitness, arterial stiffness, and blood pressure over 3 years during early childhood.
  • Mental Illness Among Youth With Chronic Physical Conditions
    John S. AdamsAlyna T. ChienLauren E. Wisk
    This nationally representative cohort study examines the risk of mental health diagnosis among youth with CPCs and explores the mediating role of activity limitations.
  • Adolescent Connectedness and Adult Health Outcomes
    Riley J. SteinerGanna SheremenkoCatherine LesesnePatricia J. DittusRenee E.SievingKathleen A. Ethier
    Using the National Longitudinal Study of Adolescent to Adult Health, we document long-term protective associations between family and school connectedness and multiple health outcomes.
  • Factors Associated With Management of Pediatric Ovarian Neoplasms
    Amy E. LawrenceDani O. GonzalezMary E. FallatJennifer H. AldrinkGeri D. HewittS. Paige HertweckAmanda OnwukaChristina BenceRobert C. BurnsPatrick A. DillonPeter F. EhrlichJason D. FraserJulia E. GrabowskiRonald B. HirschlRashmi KabreJonathan E. KohlerDave R. LalMatthew P. LandmanCharles M. LeysGrace Z. MakThomas T. SatoMadeline ScannellJoseph A. SujkaPeter C. MinneciKatherine J. Deans
    Through retrospective review of >800 patients, we describe the current approach to ovarian masses, both benign and malignant, in the pediatric patient.
  • Neurologic Outcome After Prematurity: Perspectives of Parents and Clinicians
    Monica E. LemmonHanna HuffstetlerMary Carol BarksChristine KirbyMadelaineKatzPeter A. UbelSharron L. DochertyDebra Brandon
    This qualitative descriptive study illustrates that parents and clinicians discuss and weigh prognostic information differently from each other as they consider choices for premature infants.
  • Social Robots for Hospitalized Children
    Deirdre E. LoganCynthia BreazealMatthew S. GoodwinSooyeon JeongBriannaO’ConnellDuncan Smith-FreedmanJames HeathersPeter Weinstock
    SRs offer unique opportunities to extend emotionally responsive care among limited human resources. We explore feasibility and acceptability of integrating SR technology into pediatric health care.
  • Defining Global Health Tracks for Pediatric Residencies
    Heather HaqAdelaide BarnesManeesh BatraTania ConduracheMichael B. PittJeff A.RobisonChuck SchubertNicole St ClairOmolara UwemedimoJennifer WattsChristiana M. Russ
    We present a consensus definition, minimal educational offerings and institutional supports, and evaluation methods for a GH track in pediatric residency using Delphi methodology.
  • Characteristics and Workload of Pediatricians in China
    Yongjun ZhangLisu HuangXin ZhouXi ZhangZheng KeZhaoxi WangQiang ChenXiangyu DongLizhong DuJianpei FangXing FengJianhua FuZhixu HeGuoyingHuangSongming HuangXiuli JuLi GaoLi LiTingyu LiYarui LiGeli LiuWenjun LiuXiaoping LuoGuangming NongJiahua PanKunling ShenHongmei SongJinghui SunDezhi MuTianyou WangBaoxi WangWei XiangChangyi YangShufen YangZhengyan ZhaoHua ZhuYimin ZhuJun ZhangJulian LittleTherese HeskethKun Sun
    Through a national survey, we found that uneven development of the pediatric care system is the major challenge facing China’s pediatric health care system.

Commentaries

From the American Academy of Pediatrics

Pediatrics Perspectives

Monthly Feature

Review Articles

State-of-the-Art Review Article

Special Articles

  • Spread of Measles in Europe and Implications for US Travelers
    Kristina M. AngeloPaul A. GastañaduyAllison T. WalkerManisha PatelSusan ReefC. Virginia LeeJeffrey Nemhauser
    The record number of measles cases in the WHO European Region puts both international travelers and nontraveling US residents at risk for measles.
  • Firearm Injuries and Children: Position Statement of the American Pediatric Surgical Association
    John K. PettyMarion C.W. HenryMichael L. NanceHenri R. FordAPSA Board of Governors
    The increase in firearm injuries affects all pediatric care providers. The APSA recommends improved trauma care, research, prevention, and policy to address this public health problem.

Ethics Rounds

  • Allowing Adolescents to Weigh Benefits and Burdens of High-stakes Therapies
    Kriti PuriJanet MalekCaridad Maylin de la UzJohn LantosAntonio Gabriel CabreraErnest Frugé
    In this case study, we discuss the ethical considerations when there is discordance between an adolescent close to attaining age of majority and the parent currently responsible for medical decision-making in a high-risk medical setting.

Quality Reports

  • Five-Year Outcomes of Behavioral Health Integration in Pediatric Primary Care
    Heather J. WalterLouis VernacchioEmily K. TrudellJonas BrombergEllen GoodmanJessica BartonGregory J. YoungDavid R. DeMasoGlenn Focht
    In this study, we describe the 5-year outcomes of BH integration in a large pediatric primary care network in patient experience, cost, and provider satisfaction domains.
  • Addressing Disparities in Mother’s Milk for VLBW Infants Through Statewide Quality Improvement
    Margaret G. ParkerLaura A. BurnhamPatrice MelvinRachana SinghAdriana M.LoperaMandy B. BelfortJames M. MosesMunish Gupta
    We report findings from a 3-year Massachusetts statewide QI collaborative that aimed to improve mother’s milk provision and reduce racial and ethnic disparities.

Diagnostic Dilemmas

  • Hypotonia and Lethargy in a Two-Day-Old Male Infant
    Adrienne H. LongJennifer G. FioreRiaz GillaniLaurie M. DouglassAlan M. FujiiJodi D.Hoffman
    The case of a 2-day-old term male infant found in the newborn nursery to be hypotonic and minimally reactive is discussed.

Case Reports

  • Suspicion and Persistence: A Case of Pediatric Brugada Syndrome
    Brynn E. DechertMartin J. LaPageMitchell I. Cohen
    This case study highlights the difficulty in diagnosing Brugada syndrome in a young patient with a normal electrocardiogram result at baseline.
  • Sacral Myeloradiculitis: An Uncommon Complication of Genital Herpes Infection
    Allison M. WhalenCamila M. MateoAmanda S. GrowdonAndrew F. Miller
    An 18-year-old man with genital HSV infection presents with constipation, urinary retention, paresthesias, and MRI findings of sacral myeloradiculitis.
  • Inflammatory Arthritis as a Possible Feature of Coffin-Siris Syndrome
    Sonia Melo GomesCristina DiasEbun OmoyinmiSandrine Compeyrot-LacassagneNigel KleinNeil J. SebirePaul Brogan
    Case report of a young boy with true inflammatory arthritis and diagnosis of CSS. Inflammatory arthritis may be under-recognized in chromatin remodeling–associated genetic syndromes.

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