Impact of Long Wavelength Ultraviolet A1 and Visible Light on Light‐Skinned Individuals
Indermeet Kohli  Raheel Zubair  Alexis B. Lyons  Amanda F. Nahhas  Taylor L. Braunberger  Mohsen Mokhtari  Eduardo Ruvolo  Henry W. Lim  Iltefat H. Hamzavi
First published: 25 July 2019 https://doi.org/10.1111/php.13143
This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/php.13143
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Abstract
Solar radiation is known to be a major contributor to the development of skin cancer. Most sunscreen formulations, including those with broad spectrum, offer minimal protection in long wavelength ultraviolet A1 (UVA1; 370‐400 nm) and visible light (VL; 400‐700 nm) domain. There is limited information regarding the impact of this broad waveband (VL+UVA1, 370‐700 nm) on those with light skin. In this study, ten healthy adult subjects with Fitzpatrick skin phototypes I‐III were enrolled. On day 0, subjects' lower back was exposed to a VL+UVA1 dose of 480 J/cm2. A statistically significant increase in erythema immediately after irradiation compared to subjects' baseline non‐irradiated skin was observed. Clinically perceptible erythema with VL+UVA1 is a novel finding since the erythemogenic spectrum of sunlight has primarily been attributed to ultraviolet B and short wavelength ultraviolet A (320‐340 nm). The results emphasize the need for protection against this part of the solar spectra and warrant further investigation.