HNL (Human Neutrophil Lipocalin) and a multimarker approach to the distinction between bacterial and viral infections.

Sun Jun 23, 2019 00:00

by Journal of Immunological Methods via Journal of Immunological Methods

CONCLUSION: The diagnostic performance of whole blood activated HNL was superior in the distinction between bacterial or viral infections. The addition of IP-10 and/or TRAIL to the diagnostic algorithm increased the performance of B-HNL further. The rapid analysis of HNL, reflecting bacterial infections, together with biomarkers reflecting viral infections may be the ideal combination of diagnostic biomarkers of acute infections. PMID: 31242445 [PubMed - as supplied by publisher] (Source: Journal of Immunological Methods)