Influenza A (H1N1) pdm09 virus infection in a patient with incomplete Kawasaki disease: A case report.
Author information
- 1
- Department Second of Infectious Diseases.
- 2
- Department of Respiratory, Xi'an Children's Hospital, Xi'an, Shaanxi Province, China.
Abstract
RATIONALE:
Kawasaki disease (KD) is a vasculitic illness of childhood associated with coronary artery dilatation, coronary artery aneurysm, arrhythmia, sudden death, and other serious cardiovascular diseases. Up to date, the etiology of KD remains unclear; however, epidemiological characteristics indicate that it may be related to as-yet-undefined pathogen infection.
PATIENT CONCERNS:
A 19-month-old boy had a fever of unknown origin at 38°C for 9 days without rash, runny nose and cough.
DIAGNOSIS:
The boy was diagnosed with incomplete KD (IKD) coincident with influenza A (H1N1) pdm09 virus.
INTERVENTIONS:
He was received treatments including human immunoglobulin (2 g/kg), aspirin (30∼50 mg/kg.d), and dipyridamole (3∼5 mg/kg.d).
OUTCOMES:
After 24 hours of human immunoglobulin infusion, his body temperature returned normal. After hospitalization for 6 days, his symptoms disappeared and discharged from the hospital.
LESSONS:
More attention should be paid to the correlation between KD and pathogen infection, especially the new influenza virus H1N1. The potential mechanism underlying viral infection-mediated KD is worthy of further investigation, which may provide scientific evidence for the pathogenesis of KD.
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