1
A Phase 3 Telavancin Staphylococcus Aureus (S. Aureus) Bacteremia Trial
Drug: Telavancin
Drug: Vancomycin
Drug: Daptomycin
(and 2 more...)
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Remington-Davis Clinical Research Columbus, Ohio, United States
2
Therapeutic Drug Monitoring and Continuous Infusion of Beta-lactam Antibiotics in Patients With Bacteraemia
Drug: Continuous infusion of beta-lactam antibiotics .
Other: Therapeutic drug monitoring of beta-lactam antibiotics.
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
3
Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness: A Pilot RCT
Other: 7 days of adequate antibiotic treatment durations
Other: 14 days of adequate antibiotic treatment durations
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Foothills Hospital Calgary, Alberta, Canada
University of Alberta Hospital Edmonton, Alberta, Canada
Royal Columbian Hospital Vancouver, British Columbia, Canada
(and 14 more...)
4
A New Antibiotic Prophylaxis Regimen to Prevent Bacteremia Following Dental Procedures
Drug: Amoxicillin-Potassium Clavulanate
Drug: Amoxicillin
Drug: Chlorhexidine
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Care Provider, Outcomes Assessor)
Primary Purpose: Prevention
Hospital Clinico Universitario de Santiago Santiago de Compostela, A Coruña, Spain
Santiago de Compostela University Hospital Santiago de Compostela, Coruña, Spain
5
Empirical Antibiotic and Outcome in Community-onset Bacteremia
Observational Model: Cohort
Time Perspective: Prospective
Worapong Nasomsong Bangkok, Thailand
6
Spanish Bacteriemia Cohort 2016: Epidemiology, Clinical Management and Prognosis Factors
Observational Model: Cohort
Time Perspective: Prospective
Public Health Agency Business Hospital de Poniente. El Ejido, Almería, Spain
General Hospital of Granollers Granollers, Barcelona, Spain
University Hospital Mútua de Terrasa Terrassa, Barcelona, Spain
(and 26 more...)
7
Prevalence and Characterization of Diagnostic Error Among Patients With Bacteremia
Observational Model: Other
Time Perspective: Retrospective
8
Incidence of Bacteremia Following Argon Plasma Coagulation in Patients With Endobronchial Lesions
Observational Model: Cohort
Time Perspective: Prospective
9
Virulence Determinants in S AureusBacteremia
Observational Model: Case Control
Time Perspective: Retrospective
Duke University Medical Center Durham, North Carolina, United States
10
Study to Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Participants With Staphylococcus AureusBacteremia Receiving Standard-of-Care (SOC) Antibiotics
Drug: DSTA4637S
Drug: Placebo
Drug: SOC
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Treatment
Los Angeles Biomedical Research Institute at Harbor-UCLA Torrance, California, United States
Tufts Medical Center Boston, Massachusetts, United States
Henry Ford Health System Detroit, Michigan, United States
(and 14 more...)
11
Detecting Infections Rapidly and Easily forBacteremia Trial (DIREBT)
Observational Model: Case Control
Time Perspective: Prospective
Cooper Medical School Camden, New Jersey, United States
12
Staphylococcus Aureus Bacteraemia in Adults
Staphylococcus Aureus Bacteremia
Observational Model: Cohort
Time Perspective: Prospective
Uniklinik Koln Cologne, NRW, Germany
Uniklinik Freiburg Freiburg, Germany
Univeritatklinikum Schleswig-Holstein Lübeck, Germany
(and 21 more...)
13
Staphylococcus Aureus Bacteremia : Impact of an Intervention Program in Improving the Clinical Management and Review of the Clinical and Molecular Epidemiology
Staphylococcus Aureus Bacteremia
Behavioral: Follow recommendations based on scientific evidence to S. aureus bacteremia management
Behavioral: Not to follow recommendations based on scientific evidence to S. aureus bacteremia management
Observational Model: Cohort
Time Perspective: Prospective
Hospital de Puerto Real Puerto Real, Cádiz, Spain
Hospital Costa del Sol Marbella, Málaga, Spain
Hospital de Torrecárdenas Almería, Spain
(and 13 more...)
14
Antibiotic Durations for Gram-negativeBacteremia
Bacteraemia Caused by Gram-Negative Bacteria
Other: "Fixed long" antibiotic course of 14 days
Other: "Fixed short" antibiotic course of 7 days
Other: "Individualized duration" of antibiotic therapy
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Cantonal Hospital St Gallen St. Gallen, Saint Gallen, Switzerland
Lausanne University Hospital Lausanne, Vaud, Switzerland
Geneva University Hospitals Geneva, Switzerland
15
A Prospective Observational Study of Patients With Drug Resistant Acinetobacter BaumanniiBacteremia
Acinetobacter Bacteraemia
Observational Model: Cohort
Time Perspective: Prospective
Yunlinn NTUH Branch Douliou, Taiwan
Far Eastern Memorial Hospital New Taipei, Taiwan
National Taiwan University Hospital Taipei, Taiwan
16
PVP Iodine Effect on Post DebridementBacteraemia
Bacteraemia Post Debridement
Drug: Supra- and subgingival rinsing with 10% PVP-iodine
Other: Water
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Prevention
Clinic for Preventive Dentistry, Perioodntology and Cariology, University of Zurich Zurich, ZH, Switzerland
17
Safety & Efficacy of Daptomycin Versus Standard of Care (SOC) in 1 - 17 Year Olds With Staphylococcus Aureus Bacteremia (MK-3009-005)
Drug: Daptomycin
Drug: Comparator
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
18
Establish Quantitative PCR to Measure Bacteria Load of the VRE Bacteremia
Observational Model: Case-Only
Time Perspective: Prospective
national Taiwan University Hospital Taipei, Taiwan
19
Clinical Outcomes and Cost of Gram NegativeBacteremia
Gram-negative Bacteremia
Bacteremia
Observational Model: Cohort
Time Perspective: Prospective
Duke University Medical Center Durham, North Carolina, United States
20
Non-inferiority Trial Comparing Cloxacillin vs Cefazolin in Methicillin-susceptible Staphylococcus Aureus Bacteremia
Bacteremia Due to Methicillin Susceptible Staphylococcus Aureus
Drug: Cloxacillin
Drug: Cefazolin
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
François-Xavier Lescure Paris, France
21
Study of the Impact of the Minimum Inhibitory Concentration and Susceptible Cut-off Points (CLSI, EUCAST, and Pharmacokinetics/Pharmacodynamics)in Prognosis of Bacteremia by Enterobacteriaceae
Bacteremia by Enterobacteriaceae
Other: Microbiological studies
Observational Model: Cohort
Time Perspective: Prospective
Hospital Universitario de Bellvitge L'Hospitalet de Llobregat, Barcelona, Spain
Hospital Son Espases Palma de Mallorca, Mallorca, Spain
Hospital Clínic Barcelona, Spain
(and 11 more...)
22
Seven Versus Fourteen Days of Treatment in Uncomplicated Staphylococcus AureusBacteremia
Staphylococcus Aureus Bacteremia
Drug: Antibiotic therapy duration for 7 days
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Hvidovre Hospital Hvidovre, Copenhagen, Denmark
23
Duration of Antibiotics for the Treatment of Gram-negative Bacilli Bacteremia
Drug: short-course antibiotic treatment
Drug: accepted prolonged antibiotic treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Rambam Health Care Center Haifa, Israel
Rabin medical center, Beilinson Hospital Petah Tikvah, Israel
Policlinico di Modena, Italy Modena, Emilia Romagna, Italy
24
Vancomycin Versus Daptomycin for the Treatment of Methicillin Resistant Staphylococcus Aureus (MRSA) Bacteremia
Bacteremia Due to Staphylococcus Aureus
Drug: Daptomycin
Drug: Vancomycin
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Singapore General Hospital Singapore, Singapore
25
Ceftobiprole in the Treatment of Hospitalized Patients With Staphylococcus AureusBacteremia
Drug: ceftobiprole medocaril
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
26
Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia
Staphylococcus Aureus Bacteremia
Drug: Ceftobiprole medocaril
Drug: Daptomycin
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
6701 Airport Boulevard Mobile, Alabama, United States
eStudy Site - Chula Vista - PPDS Chula Vista, California, United States
eStudy Site - La Mesa - PPDS La Mesa, California, United States
(and 25 more...)
27
Efficacy of Daptomycin Plus Fosfomycin Versus Daptomycin for Treatment of MRSABacteremia
Staph Aureus Methicillin Resistant Bacteremia
Drug: Fosfomycin 2gr/6h iv
Drug: Daptomycin 10mg/kg/24h iv
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Hospital Universitari de Bellvitge Hospitalet de Llobregat, Barcelona, Spain
Hospital Parc Taulí Sabadell, Barcelona, Spain
Hospital Universitari Mútua de Terrassa Terrassa, Barcelona, Spain
(and 15 more...)
28
The Benefit of FDG PET CT in the Treatment Algorithm of Staphylococcus AureusBacteremia
Staphylococcus Aureus Bacteremia
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Rambam Health Care Campus Haifa, Israel
29
Rapid Identification and Phenotypic Susceptibility Testing for Gram-NegativeBacteremia
Device: Accelerate PhenoTest™ BC Kit
Device: Standard Culture and AST
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Care Provider)
Primary Purpose: Diagnostic
University of California, Los Angeles Los Angeles, California, United States
Mayo Clinic Rochester, Minnesota, United States
30
A Study of the Safety and Efficacy of 514G3 in Subjects Hospitalized With Bacteremia Due to Staphylococcus Aureus
Staphylococcus Aureus Bacteremia
Biological: 514G3
Drug: Placebo
Drug: Standard IV antibiotic therapy
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Treatment
XBiotech Investigative Site Columbus, Georgia, United States
XBiotech Investigative Site Charlotte, North Carolina, United States
31
Recurrent ESBL-producing EnterobacteriaceaeBacteremia : Risk Factor, Molecular Character and Susceptibility Change
Observational Model: Case Control
Time Perspective: Retrospective
Chang Gung Medical Foundation, Kaohsiung Branch Kaohsiung, Taiwan
32
BALANCE on the Wards: A Pilot RCT
Other: 7 days of adequate antibiotic treatment
Other: 14 days of adequate antibiotic treatment
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Hamilton General Hospital Hamilton, Ontario, Canada
Kingston General Hospital Kingston, Ontario, Canada
The Ottawa Hospital Ottawa, Ontario, Canada
(and 3 more...)
33
Treatment of Hemodialysis Catheter-RelatedBacteremia
Hemodialysis Catheter-related Bacteremia
Drug: tigecycline, N-acetylcysteine, heparin combination
Device: guide-wire exchange
Allocation: Randomized
Masking: None (Open Label)
University of California, San Diego Medical Center San Diego, California, United States
34
Direct Thrombin Inhibitors Versus LMWH in Staphylococcus Aureus Bacteraemia
Staphylococcus Aureus Bacteraemia
Drug: direct thrombin inhibition
Drug: enoxaparin
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
KUleuven/UZ Gasthuisberg Leuven, Belgium
35
Clinical Trial Comparing Safety and Pharmacokinetics of Standard Antibiotic Therapy, Plus Aurexis® or Placebo, for Treatment of Staphylococcus AureusBacteremia (SAB)
Staphylococcus Aureus Bacteremia
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
36
Daptomycin as Adjunctive Therapy for Staphylococcus Aureus Bacteremia
Methicillin Susceptible Staphylococcus Aureus Septicemia
Bacteremia
Drug: Daptomycin
Other: Placebo
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
McGill University Health Centre (Royal Victoria Hospital, Montreal Neurological Hospital, and Montreal General Hospital) Montreal, Quebec, Canada
37
Bacteraemia Secondary to Tooth Extraction: Chlorhexidine Prophylaxis Protocols
Bacteremia
Tooth Extraction Status Nos
Drug: 0.2% Chlorhexidine
Drug: 1% Chlorhexidine
Procedure: Blood extraction
(and 2 more...)
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Investigator, Outcomes Assessor)
Primary Purpose: Prevention
Department of Stomatology and Maxillofacial Surgery of the Santo Antonio General Hospital Oporto, Portugal
Department of Stomatology University of Santiago de Compostela Santiago de Compostela, Galicia/A Coruña, Spain
38
An Oral Amoxicillin-Clavulanate Regimen to Prevent Bacteremia Following Dental Procedures
Drug: Amoxicillin
Drug: Amoxicillin-Potassium Clavulanate
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Prevention
Hospital Clinico Universitario de Santiago Santiago de Compostela, A Coruña, Spain
Santiago de Compostela University Hospital Santiago de Compostela, Coruña, Spain
39
IL-10 Stratifying Tool for Towards Antibiotic Selection for MRSaB
Drug: Daptomycin
Drug: Vancomycin
Drug: Ceftaroline
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Sharp Grossmont Hospital La Mesa, California, United States
Sharp Memorial Hospital San Diego, California, United States
40
Effect of dRAST on Treatment for Bacteremia in Patients With Hematologic Diseases
Hematologic Diseases
Bacteremia Sepsis
Diagnostic Test: dRAST
Diagnostic Test: Current standard method
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Seoul National University Hospital Seoul, Korea, Republic of
41
Safety and Efficacy Study of Ceftaroline in Subjects With Staphylococcus AureusBacteremia or With Persistent Methicillin-Resistant Staphylococcus Aureus Bacteremia
Staphylococcus Aureus Bacteremia
Methicillin-resistant Staphylococcus Aureus (MRSA) Bacteremia
Drug: Ceftaroline fosamil
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Investigational Site Birmingham, Alabama, United States
Investigational Site Sacramento, California, United States
Investigational Site San Francisco, California, United States
(and 24 more...)
42
Factors Associated With Increased Risk ofBacteremia and Cholangitis in ERCP With Cholangioscopy
Procedure: Cholangioscopy
Observational Model: Cohort
Time Perspective: Prospective
Baylor College of Medicine Houston, Texas, United States
43
Bacteria Entering the Blood Stream From Tooth Extractions and Tooth Brushing
Drug: Effect of Amoxicillin on bacteremia following a single-tooth extraction
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Prevention
Carolinas Medical Center Dental Clinic Charlotte, North Carolina, United States
44
Procalcitonin Levels as a Predictor ofBacteremia in Febrile Pediatric Oncology Patients-Pilot Study
Observational Model: Cohort
Time Perspective: Prospective
CAMC Health Systems Charleston, West Virginia, United States
45
Piperacillin/Tazobactam for Bacteremia With Organisms Producing Chromosomally-Encoded AmpC Beta-Lactamase
Bacteremia
AmpC Beta-lactamase
Observational Model: Other
Time Perspective: Retrospective
University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States
46
Bacteremia in Intensive Care Unit (ICU)
Bacteremia and Sepsis
Toll-Like-Receptors (TLRs)
Observational Model: Cohort
Time Perspective: Prospective
Zakynthinos E Larisa, Mezourlo, Greece
47
Safety, Efficacy and Pharmacokinetics of CF-301 vs. Placebo in Addition to Antibacterial Therapy for Treatment of S. AureusBacteremia
Staphylococcus Aureus Bacteremia
Staphylococcus Aureus Endocarditis
Biological: CF-301
Drug: Placebo
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
CF-301-102 Study Site Birmingham, Alabama, United States
CF-301-102 Study Site Sacramento, California, United States
CF301-102 Study Site Sylmar, California, United States
(and 75 more...)
48
Safety Evaluation of Seraph® 100 to ReduceBacteremia in Patients on Hemodialysis
Bacteremia
Bacterial Infection
Device: Seraph 100 Filter
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Klinikum Braunschweig Braunschweig, Germany
Universitaetsklinikum-Frankfurt Frankfurt, Germany
Medizinische Hochschule-Hannover Hannöver, Germany
Universitatsklinikum Muenster Muenster, Germany
49
Early Infectious Disease Consultations in Staphylococcus Aureus Bacteremia
Staphylococcus Aureus Bacteremia
Other: infectious disease specialist consultation
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Health Services Research
National University Hospital Singapore, Singapore
50
Clinical and Medico-economic Evaluation of a Rapid Test (ePlex-BCID®, GenMark) for the Diagnosis of Bacteremia and Fungemia.
Bacteremia Sepsis
Fungemia
Diagnostic Test: Multiplex PCR
Diagnostic Test: Current strategy alone
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Diagnostic
Grenoble University Hospital Grenoble, France
51
Turkish Prospective Cohort Study on Carbapenem Resistant Klebsiella PneumoniaBacteremia
Klebsiella Pneumonia
Bacteremia
Drug: Combination therapy
Observational Model: Cohort
Time Perspective: Prospective
Ankara University Ankara, Turkey
Başkent University Ankara, Turkey
Hacettepe University Ankara, Turkey
(and 13 more...)
52
Comparison Trial for Chloraprep Versus Aqueous Chlorhexidine (2%) for the Prevention of Catheter-related Bacteremia
Sepsis Affecting Skin
Central Venous Catheter Related Bacteremia
Drug: A (Chloraprep)
Drug: B (Clorhexidine 2%)
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
53
Comparison of Nephrotoxicity and Hospital Costs in Patients With Methicillin-Resistant Staphylococcus Aureus Bacteremia Who Received Vancomycin Versus Teicoplanin Therapy
Staphylococcus Aureus
Bacteremia
Taipei Medical University - WanFang Hospital Taipei, Taiwan
54
Preventing Catheter-related Bacteremia When Administering Injectable Medications in Premature Infants.
Bacteremia
Infant, Very Low Birth Weight
Device: Edelvaiss Multiline NEO
Device: Standard Infusion Set
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single (Participant)
Primary Purpose: Prevention
Hôpital Nord - CHU d'Amiens Amiens, France
Hôpital Côte de Nacre - CHU de Caen Caen, France
Hôpital Jeanne de Flandre - CHRU de Lille Lille, France
Hôpital Charles Nicolle - CHU de Rouen Rouen, France
55
Vancomycin Versus Daptomycin for the Treatment of Methicillin-resistant Staphylococcus Aureus Bacteremia Due to Isolates With High Vancomycin Minimum Inhibitory Concentrations (MICs)
Drug: Vancomycin
Drug: Daptomycin
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
56
A Study on the Tolerability and Early Efficacy of hLF1-11 in Patients With Bacteremia Due to S. Epidermidis
Staphylococcal Infections
Bacteremia
Drug: human lactoferrin peptide 1-11
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Care Provider, Investigator)
Primary Purpose: Treatment
UMC St. Radboud Nijmegen, Gelderland, Netherlands
57
Efficacy and Safety of Dalbavancin Compared to Standard of Care Antibiotic Therapy for the Completion of Treatment of Patients With Complicated Bacteremia or Infective Endocarditis
Drug: Dalbavancin
Drug: Standard of Care
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Midway Immunology and Research Center Fort Pierce, Florida, United States
58
Imipenem and Sulbactam in the Treatment of Imipenem-resistant Acinetobacter BaumanniiBacteremia
Acinetobacter Bacteraemia
Observational Model: Case Control
Time Perspective: Retrospective
Taipei Veterans General Hospital, Taiwan Taipei, Taiwan
59
Prevalence of CVC-associated Sepsis and Use of Blood Cultures in Berlin - Brandenburg
Observational Model: Cohort
Time Perspective: Retrospective
Department of Anesthesiology and Intensive Care Medicine, Campus Virchow-Klinikum and Campus Charité Mitte, Charité - Universitaetsmedizin Berlin Berlin, Germany
60
Diagnosis of Bacteremia /Septicemia and Culture Negative Endocarditis by the Karius Sequencing-Based Infectious Disease Diagnostic Assay
Observational Model: Cohort
Time Perspective: Other
Duke University Hospital Durham, North Carolina, United States
61
Daptomycin in the Treatment of Subjects With Infective Endocarditis or Bacteremia Due to S. Aureus
Bacterial Endocarditis
Bacteremia
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
62
Device for Bacteremia Prevention in Post Cardiac Surgical Intensive Care Unit Patients
Infection
Heart; Surgery, Heart, Functional Disturbance as Result
Bacteremia
Device: Chlorhexidine flush
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Hamilton Health Sciences Hamilton, Ontario, Canada
63
Clinical Impact of Fluoroquinolone Resistance in Bacteremia Caused by Gram-Negative Bacilli of Urinary Tract Origin
Urinary Tract Infection
Fluoroquinolone
Bacteremia
Observational Model: Other
Time Perspective: Retrospective
University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States
64
Increasing the Yield of Blood Cultures in Neonates
Other: 1cc of blood in a single aerobic culture bottle
Allocation: Non-Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
65
Effectiveness of Routine Sterile Gloving in Blood Culture
Behavioral: Routine sterile gloving
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Diagnostic
Seoul National University Hospital Seoul, Korea, Republic of
66
Taurolidine Lock Solution in the Prevention of Catheter Related Bacteremia
Device: Taurolock
Device: Heparin
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Childrens Department of Oncology A4, Aarhus Universityhospital, Skejby Århus N, Denmark
67
A Cluster-randomized Cross-over Trial Evaluating the Comparative Effectiveness of Three Skin Antiseptic Interventions
Drug: Iodine tincture
Drug: Chlorhexidine gluconate
Drug: Povidone iodine
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary Purpose: Prevention
68
The Value of sTREM-1, PCT, and CRP as Markers for the Detection of Sepsis andBacteremia Among Patients With a FUO
Observational Model: Case Control
Time Perspective: Prospective
Chinese PLA General Hospital Beijing, Beijing, China
69
Blood Cultures's Profitability in Intensive Care Unit
Observational Model: Other
Time Perspective: Prospective
Hopsital Universitario de Getafe Getafe, Madrid, Spain
70
T2Bacteria Panel Pivotal Study
Observational Model: Cohort
Time Perspective: Prospective
Henry Ford Health System Detroit, Michigan, United States
University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States
Rhode Island Hospital Providence, Rhode Island, United States
71
Efficacy of Cefepime Continuous Infusion Versus an Intermittent Dosing Regimen
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Hospital San Juan de Dios Rionegro, Antioquia, Colombia
Clinica Palermo Bogota, DC, Colombia
Fundacion San Carlos Bogota, DC, Colombia
(and 4 more...)
72
Phase IIa Clinical Study of N-Rephasin® SAL200
Staphylococcus Aureus Bacteremia
Anti-Bacterial Agents
Biological: N-Rephasin® SAL200
Other: Placebo
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Seoul National University Bundang Hospital Seongnam-si, Gyeonggi-do, Korea, Republic of
Seoul National University Hospital Seoul, Korea, Republic of
73
Efficacy of 2% Chlorhexidine Gluconate in 70% Alcohol Compare 10% Povidone Iodine in Blood Culture in Children
Drug: 2% chlorhexidine gluconate in 70% alcohol
Drug: 10%povidone iodine
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Thammasat University hospital Klong luang, Pathumthanii, Thailand
74
Study of the Performance of the KeyPath MRSA/MSSA Blood Culture Test - BTA
Observational Model: Case Control
Time Perspective: Prospective
University of Arizona, Infectious Disease Research Tuscon, Arizona, United States
UCLA Clinical Laboratory Los Angeles, California, United States
Medical University of South Carolina Charleston, South Carolina, United States
75
Hub Cleansing to Prevent Hub Infection
Other: 15 second scrub
Other: 5 second scrub
Drug: 3.15% chlorhexidine/70% isopropyl alcohol
Drug: 70% isopropyl alcohol
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Double (Participant, Care Provider)
Primary Purpose: Prevention
Rush University Medical Center Chicago, Illinois, United States
76
Multicenter Blood Culture Quality Improvement
Other: Blood Culture QI Program
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Vanderbilt Emergency Medicine Nashville, Tennessee, United States
Vanderbilt University Medical Center Emergency Medicine Nashville, Tennessee, United States
77
Treatment Algorithm to Reduce the Use of Vancomycin in Adults With Blood Stream Infection
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
University of Alabama, Birmingham Birmingham, Alabama, United States
David Geffen School of Medicine UCLA Los Angeles, California, United States
University of Colorado Denver, Colorado, United States
(and 12 more...)
78
Ethanol Lock for the Salvage of Infected Long-term Vascular Access
Drug: Ethanol-lock therapy
Drug: Antibiotic-lock
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Fondazione IRCCS Policlinico "San Matteo" Pavia, PV, Italy
79
Prospective Study Into the Performance of the MicroPhage S. Aureus/MSSA/MRSA Test Direct From Blood Culture Positives
Device: MicroPhage S. aureus/MSSA/MRSA Blood Culture Test
Time Perspective: Prospective
80
Daptomycin Pharmacokinetics in Continuous Veno-venous Hemodiafiltration
Allocation: Non-Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Medical Intensive Care Unit, University Hospital Zurich Zurich, Switzerland
81
Amoxicillin to Prevent Bacteria and Inflammatory Biomarkers After Intensive Periodontal Therapy
Chronic Periodontitis
Bacteremia
Drug: Amoxicillin
Other: Placebo
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Luis Antonio Noriega Frontado Bogotá, Bogotá D.C, Colombia
82
The Impact of Material on Microbiota in Association With Tongue and Lip Piercing
Device: piercings of four different materials
Observational Model: Case Control
Time Perspective: Prospective
Innsbruck Medical University Innsbruck, Austria
83
Prevention of Bacteremia Induced by Debridement of Pressure Ulcer
Pressure Ulcers
Bacteremia
Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective
Herzog Hospital Jerusalem, Israel
84
Central Venous Catheter Lock Solution
Other: citrate
Other: heparin
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose: Prevention
Department of Dialysis Tuzla, TK, Bosnia and Herzegovina
85
Impact MRSA -PCR on Patient Management
Diagnostic Test: Polymerase Chain Reaction of Methicillin Resistant Staphyloccus Aureus
Observational Model: Cohort
Time Perspective: Retrospective
Groupe Hospitalier Paris Saint Joseph Paris, Ile-de-France, France
86
Prophylactic Antimicrobial Catheter Lock
Drug: Heparin 1000U/mL
Drug: 4% Sodium Citrate with Gentamicin 320 mcg/mL
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double (Participant, Care Provider)
Primary Purpose: Treatment
Satellite Healthcare, Inc Mountain View, California, United States
87
Safety, Efficacy, and Pharmacokinetics (PK) of Daptomycin (MK-3009) in Japanese Pediatric Subjects With Complicated Skin and Soft Tissue Infections (cSSTI) and Bacteremia (MK-3009-029)
Bacteremia
Soft Tissue Infections
Skin Diseases, Infectious
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Japan Community Health Care Organization Chukyo Hospital ( Site 0030) Nagoya, Aichi, Japan
Japan Community Health care Organization Kyushu Hospital ( Site 0016) Kitakyushu, Fukuoka, Japan
Maebashi Red Cross Hospital ( Site 0012) Maebashi, Gunma, Japan
(and 13 more...)
88
The Only Blood Culture for Diagnosis ofBacteremia - Comparative Study of Practice
Procedure: Single-sampling strategy vs multi-sampling strategy for the diagnosis of bacteremia
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
89
Safety and Efficacy of Dalbavancin Versus Vancomycin in the Treatment of Catheter-Related Bloodstream Infections
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Wellstar/Kennestone Hospital Marietta, Georgia, United States
90
Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness
Bacteremia
Intensive Care
Critically Ill
(and 3 more...)
Other: 7 days of adequate antibiotic treatment
Other: 14 days of adequate antibiotic treatment.
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Cabrini Health Melbourne, Australia
Dandenong Hospital- Monash Health Melbourne, Australia
Monash Medical Centre Melbourne, Australia
(and 39 more...)
91
Efficacy of a Short-term Sequential Therapy in Non-complicated Catheter Related Bacteremia by Methicillin- Susceptible S.Aureus.
Drug: Cloxacilin
Drug: Cloxacillin
Drug: Levofloxacin
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Hospital de Jerez de la Frontera Jerez de la Frontera, Cádiz, Spain
Hospital Costa del Sol Marbella, Málaga, Spain
Hospital Universitario Reina Sofía Córdoba, Spain
(and 8 more...)
92
HeRO Vascular Access Device Bacteremia Study
Device: HeRO Vascular Access Device
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
University of Miami / Cedars Medical Center Miami, Florida, United States
St. Joseph's Hospital Atlanta, Georgia, United States
Southern Illinois University Springfield, Illinois, United States
(and 4 more...)
93
Chart Review of Outcome of Treatment for S. Aureus Bacteremia
Observational Model: Ecologic or Community
Time Perspective: Retrospective
Michael E. DeBakey Veterans Affairs Medical Center Houston, Texas, United States
94
Alcohol Locks for the Prevention of Tunneled Catheter-related Infections
Procedure: Alcohol-lock
Drug: placebo-lock
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Prevention
Erasmus Medical Center Rotterdam, Netherlands
95
Study of Daptomycin Safety and Efficacy for Complicated Skin and Skin Structure Infections (cSSSI) and Bacteremia in Renal Impairment
Complicated Skin and Skin Structure Infections
S. Aureus Bacteremia
Renal Impairment
Drug: Vancomycin
Drug: Daptomycin
Drug: Semi-Synthetic Penicillin
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Azusa, California, United States
Los Angeles, California, United States
Torrance, California, United States
(and 7 more...)
96
Predictive Value of Procalcitonin forBacteremia in the ICU
Diagnostic Test: procalcitonin measurement
Observational Model: Cohort
Time Perspective: Retrospective
Rijnstate hospital Arnhem, Gelderland, Netherlands
97
Safety and Bacteraemia Between Peripherally Inserted and Central Inserted Catheters.
Catheter Related Infections
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Hospital de la Santa Creu i Sant Pau Barcelona, Spain
98
Bloodstream Infections in Patients With Rheumatoid Arthritis
Rheumatoid Arthritis
Staphylococcus Aureus Bacteremia
Other: Risk factors in RA cohort
Other: Risk factors in general population
Observational Model: Cohort
Time Perspective: Retrospective
99
Successful Treatment of Maternal Listeria Monocytogenes Bacteremia in the First Trimester
Drug: Ampicillin Injection
Observational Model: Case-Only
Time Perspective: Retrospective
Far Eastern Memorial Hospital New Taipei, Taiwan
100
Procalcitonin Level as a Surrogate for Catheter-related Blood Stream Bacteremia Among Hemodialysis Patients
Hemodialysis Catheter Infection
Observational Model: Cohort
Time Perspective: Prospective
New jeddah clinic Hospital Jeddah, Saudi Arabia
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