A Supraglottic Mass in a Pediatric Patient: An Unusual Presentation of Lymphoma.

Perez PI1, McIlwain W1, Winters J2, Dhesi M2, Rogers DJ1.

Author information

1

1 Otolaryngology-Head and Neck Surgery, Madigan Army Medical Center, Tacoma, Washington, USA.

2

2 Department of Pathology, Madigan Army Medical Center, Tacoma, Washington, USA.

Abstract

OBJECTIVE::

To present a case of laryngeal lymphoma in a pediatric patient and perform a literature review of this rare entity.

PATIENT::

A 13-year-old male presented with a rapidly enlarging right neck mass. Work-up of the neck mass included a computed tomography scan of the neck with contrast and revealed a 2.5 cm right level II neck mass and an asymmetric lobulated soft tissue mass in the right pyriform sinus.

INTERVENTION::

The patient underwent excisional biopsy of the right supraglottic mass. Once his diagnosis was confirmed, he was treated with a standard lymphoma protocol.

RESULTS::

Intraoperative frozen analysis revealed a small blue cell tumor. Final pathology demonstrated diffuse large B-cell lymphoma of the germinal center B-cell subtype (GC-DLBCL). The patient underwent treatment with primary chemotherapy 12 days after his original procedure with cyclophosphamide, doxorubicin, vincristine, and prednisone.

CONCLUSION::

Laryngeal lymphoma remains extremely rare in the pediatric population. With appropriate treatment, the 5-year disease-free survival remains excellent for germinal center diffuse large B-cell lymphoma.

KEYWORDS:

diffuse large B-cell lymphoma; lymphoma; neck mass; pediatric; supraglottis

PMID:

 

30894021

 

DOI:

 

10.1177/0003489419838544

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