A Breath of Fresh Air: BCG Prevents Adult Pulmonary Tuberculosis.

de Gijsel D1, von Reyn CF2.

Author information

1

Infectious Disease and International Health, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.

2

Infectious Disease and International Health, Geisel School of Medicine at Dartmouth, Hanover, NH, USA. Electronic address: C.Fordham.von.Reyn@dartmouth.edu.

Abstract

OBJECTIVES:

The efficacy of childhood BCG vaccination in the prevention of adult pulmonary tuberculosis is not universally accepted.

METHODS:

We reviewed the published literature and summarized studies of BCG vaccination reporting long-term protection against pulmonary TB.

RESULTS:

We identified 15 papers reporting prospective studies and their long-term follow up, retrospective studies or systematic reviews.

CONCLUSIONS:

Good quality evidence supports the efficacy of BCG vaccination in the prevention of adult pulmonary tuberculosis.

Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.

KEYWORDS:

BCG; tuberculosis; vaccine

PMID:

 

30822546

 

DOI:

 

10.1016/j.ijid.2019.02.036

[Indexed for MEDLINE] 

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