S100 Negative CD1a Positive Indeterminate Cell Histiocytosis,
Sima Amin BS Jordan Jamerson MD Ronald G. Tee MD Palak Parekh MD
First published: 06 July 2019 https://doi.org/10.1111/cup.13542
This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/cup.13542.
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Abstract
Histiocytoses are a group of rare disorders characterized by a proliferation of monocytes/macrophages and dendritic cells. We present a case of a 3‐year‐old female with a diffuse papular eruption without systemic symptoms demonstrating a proliferation of strongly CD1a positive histiocytes, but negative for S‐100 and Langerin on histopathology. Systemic work‐up including bone marrow biopsy was unremarkable, and the patient received a diagnosis of CD1a+ S‐100‐ indeterminate cell histiocytosis (ICH).
Sima Amin BS Jordan Jamerson MD Ronald G. Tee MD Palak Parekh MD
First published: 06 July 2019 https://doi.org/10.1111/cup.13542
This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/cup.13542.
ePDFPDFTOOLS SHARE
Abstract
Histiocytoses are a group of rare disorders characterized by a proliferation of monocytes/macrophages and dendritic cells. We present a case of a 3‐year‐old female with a diffuse papular eruption without systemic symptoms demonstrating a proliferation of strongly CD1a positive histiocytes, but negative for S‐100 and Langerin on histopathology. Systemic work‐up including bone marrow biopsy was unremarkable, and the patient received a diagnosis of CD1a+ S‐100‐ indeterminate cell histiocytosis (ICH).
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