Melanoma Metastatic to the Jejunum Diagnosed by Double-Balloon Enteroscopy
© 2019 by Lippincott Williams & Wilkins, Inc.
CASE REPORT
A 63-year-old man presented with a left cheek melanoma for which he underwent wide local excision (Stage IIIC). Follow-up positron emission tomography 1 year later demonstrated increased 18F-fluorodeoxyglucose uptake in the right upper lobe concerning for metastasis. Computed tomography–guided needle biopsy demonstrated metastatic malignant melanoma. He underwent stereotactic body radiation therapy. Follow-up positron emission tomography 1 year later did not show any evidence of recurrent disease. However, follow-up positron emission tomography 6 months later demonstrated new intense hypermetabolism within a ventral abdominal loop of the small bowel (Figure 1). Double-balloon enteroscopy was then performed. This revealed a nearly circumferential, ulcerated mass in the distal jejunum (Figure 2). Biopsies showed nests of malignant melanocytes confirming the diagnosis of metastatic melanoma (Figure 3). The patient was referred for surgical metastasectomy, which can confer a survival benefit compared with nonsurgical management in patients with abdominal metastases.1 Although gastrointestinal metastases are common, only 1.5%–4.4% of metastases are detected before death.2 The patient underwent exploratory laparotomy and small bowel resection. The pathology showed metastatic melanoma with negative margins and uninvolved lymph nodes. Postoperatively, he was started on an immune checkpoint inhibitor.
DISCLOSURES
Author contributions: D. Siao, M. Chang, and G. Bharadhwaj drafted the manuscript. P. George provided the technical and material support. D. Siao is the article guarantor.
Financial disclosure: None to report.
Informed consent was obtained for this case report.
REFERENCES
1. Gutman H, Hess KR, Kokotsakis JA, Ross MI, Guinee VF, Balch CM. Surgery for abdominal metastases of cutaneous melanoma. World J Surg. 2001;25(6):750–8.
2. Lens M, Bataille V, Krivokapic Z. Melanoma of the small intestine. Lancet Oncol. 2009;10(5):516–21.
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου