Fosfomycin tromethamine activity on biofilm and intracellular bacterial communities produced by uropathogenic Escherichia coli isolated from patients with urinary tract infection     Maria José González; Paula Da Cunda; Martín Notejane ; Pablo Zunino; Paola Scavone ...   Fosfomycin tromethamine reduces uropathogenic Escherichia coli biofilm, without activity on intracellular bacterial communities within the bladder.

Human papillomavirus infection and autoimmune disorders: a tertiary center experience     Hanife Guler Donmez; Atakan Tanacan; Canan Unal; Erdem Fadiloglu ; Sevgen Celik Onder...   Prevalence of autoimmune disorders was high among HPV-DNA positive women. High-risk HPV positivity, the coexistence of multiple HPV types and abnormal cytology rates were not affected by autoimmunity.

CCR7-deficient mice exhibit a delayed antigen-specific mucosal IgA antibody response to an oral recombinant Salmonellastrain     Tomomi Hashizume-Takizawa; Ryoki Kobayashi; Osamu Tsuzukibashi ; Masanori Saito; Tomoko Kurita-Ochiai   Lack of CCR7 affects the formation of secondary lymphoid follicles in PPs after administration of oral recombinant Salmonella, inducing a delayed type of Ag-specific mucosal IgA antibody response.

Lactic acid bacteria decrease Salmonella enterica Javiana virulence and modulate host inflammation during infection of an intestinal epithelial cell line     Kristin M Burkholder; Dylan H Fletcher; Lauren Gileau ; Arnold Kandolo   Lactic acid bacteria (LAB) decrease S. Javiana virulence and modulate host inflammatory response to infection.

Editor's Choice   Pichia pastoris -expressed Zika virus envelope domain III on a virus-like particle platform: design, production and immunological evaluation     Rajgokul K Shanmugam; Viswanathan Ramasamy ; Rahul Shukla; Upasana Arora; Sathyamangalam Swaminathan ...   Yeast-produced Zika virus-like particulate antigen elicits Zika virus-neutralizing, but dengue non-enhancing, Abs in mice.

Chlamydia muridarum infection induces CD4+ T cells apoptosis via PI3K/AKT signal pathway     Ningbo Zheng; Lida Sun; Gaoju Pang; Xiaoyu Zha; Wenhao Niu ...   Chlamydia muridarum(Cm) infection induces PI3K/AKT signal pathway activation, and apoptosis of CD4+ T cells induced by Cm infection possibly via PI3K/AKT signal pathway.

Characterization of two novel mutations in IL-12R signaling in MSMD patients     Elham Alipour Fayez; Zahra Koohini; Zohreh Koohini; Hossein Zamanzadeh ; Martin de Boer...   Mendelian inheritance seems to play an important role in the etiology of disseminated BCG infection

A primary study on genes with selected mutations by in vitropassage of Chlamydia muridarum strains     Zhou Zhou; Na Liu; Yingzi Wang; Arthur Wirekoh Emmanuel ; Xiaoxing You ...   Newly discovered genes in C. muridarum

Mycobacterium bovis BCG promotes IL-10 expression by establishing a SYK/PKCα/β positive autoregulatory loop that sustains STAT3 activation     Tomás Villaseñor; Edgardo Madrid-Paulino; Rafael Maldonado-Bravo ; Leonor Pérez-Martínez; Gustavo Pedraza-Alva   To skew the immune response and avoid destruction, Mycobacterium bovis BCG promotes Interleukin-10 gene expression through a SYK/PKCα/β positive autoregulatory loop that sustains STAT3 activation. Image created by BioRender.com.

Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) spa type t127, Sequence Type (ST)1, quickly spreads and persists among young pigs     Giuseppe Merialdi; Fabiola Feltrin; Barbara Gaetarelli ; Guerino Lombardi; Manuela Iurescia...   This is the first colonization/transmission study performed in piglets with a Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA), Clonal Complex (CC)1, rapidly transmitted to negative contact-piglets, which remained all positive throughout the experiment.

Evaluation of a PGP3 ELISA for surveillance of the burden of Chlamydia infection in women from Australia and Samoa     Rami Mazraani; Peter Timms ; Philip C Hill; Tamaailau Suaalii-Sauni; Tavita Niupulusu ...   The PGP3 ELISA has potential for sero-epidemiological studies of current and/or past chlamydial infection of women in a variety of settings, including high prevalence.