Antibacterial activity of new atraumatic restorative treatment materials incorporated with Azadirachta indica (Neem) against Streptococcus mutans Publication date: October–December 2019 Source: Journal of Oral Biology and Craniofacial Research, Volume 9, Issue 4 Author(s): P. Divya Kumari, Shilpa M. Shenoy, Shahnawaz Khijmatgar, Avidyuti Chowdhury, Edward Lynch, Chitta R. Chowdhury Abstract Background The antibacterial property of new atraumatic restorative treatment (ART) materials incorporated with Azadirachta indica (Neem) on Streptococcus mutans was carried out. Materials and methods The study was carried out by using the agar diffusion method to determine the antibacterial property of ART materials (ART-I and ART-II). The zone of inhibition was tabulated, and the data was statistically analyzed using the student t-test. The minimum inhibitory concentrations (MIC) and the minimum bactericidal concentrations (MBC) of the ethanolic extract of Neem were recorded. Results The MIC and MBC of the mixture of the ethanolic extract of Neem was 3.13% and 12.5% respectively. The zone of inhibition of ART-I and ART-II was 11.81 mm and 11.97 mm respectively. Significant differences were observed between these two ART materials (P = 0,08). Conclusion Both the new ART materials i.e. ART-I and ART–II have considerable antibacterial activity against S. mutans.

Neem Tree

Plants

Description

Azadirachta indica, commonly known as neem, nimtree or Indian lilac, is a tree in the mahogany family Meliaceae. It is one of two species in the genus Azadirachta, and is native to the Indian subcontinent, i.e. India, Nepal, Pakistan, Bangladesh, Sri Lanka, and Maldives. Wikipedia

Scientific name: Azadirachta indica

Family: Meliaceae

Kingdom: Plantae

Rank: Species

Higher classification: Azadirachta

Order: Sapindales

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