IJMS, Vol. 21, Pages 7414: Investigating the Transition of Pre-Symptomatic to Symptomatic Huntington’s Disease Status Based on Omics Data International Journal of Molecular Sciences doi: 10.3390/ijms21197414 Authors: Christiana C. Christodoulou Margarita Zachariou Marios Tomazou Evangelos Karatzas Christiana A. Demetriou Eleni Zamba-Papanicolaou George M. Spyrou Huntington’s disease is a rare neurodegenerative disease caused by a cytosine–adenine–guanine...
Thu Oct 08, 2020 03:00
IJMS, Vol. 21, Pages 7412: p38 MAPK Pathway in the Heart: New Insights in Health and Disease International Journal of Molecular Sciences doi: 10.3390/ijms21197412 Authors: Rafael Romero-Becerra Ayelén M. Santamans Cintia Folgueira Guadalupe Sabio The p38 mitogen-activated kinase (MAPK) family controls cell adaptation to stress stimuli. p38 function has been studied in depth in relation to cardiac development and function. The first isoform demonstrated to play an important role...
Thu Oct 08, 2020 03:00
IJMS, Vol. 21, Pages 7410: Self-Replication of Prion Protein Fragment 89-230 Amyloid Fibrils Accelerated by Prion Protein Fragment 107-143 Aggregates International Journal of Molecular Sciences doi: 10.3390/ijms21197410 Authors: Tomas Sneideris Mantas Ziaunys Brett K.-Y. Chu Rita P.-Y. Chen Vytautas Smirnovas Prion protein amyloid aggregates are associated with infectious neurodegenerative diseases, known as transmissible spongiform encephalopathies. Self-replication of amyloid...
Thu Oct 08, 2020 03:00
IJMS, Vol. 21, Pages 7408: Rose Bengal Crosslinking to Stabilize Collagen Sheets and Generate Modulated Collagen Laminates International Journal of Molecular Sciences doi: 10.3390/ijms21197408 Authors: Stefanie Eckes Joy Braun Julia S. Wack Ulrike Ritz Daniela Nickel Katja Schmitz For medical application, easily accessible biomaterials with tailored properties are desirable. Collagen type I represents a biomaterial of choice for regenerative medicine and tissue engineering....
Thu Oct 08, 2020 03:00
IJMS, Vol. 21, Pages 7409: Genetic Aspects of Inflammation and Immune Response in Stroke International Journal of Molecular Sciences doi: 10.3390/ijms21197409 Authors: Dejan Nikolic Milena Jankovic Bojana Petrovic Ivana Novakovic Genetic determinants play important role in the complex processes of inflammation and immune response in stroke and could be studied in different ways. Inflammation and immunomodulation are associated with repair processes in ischemic stroke, and together...
Thu Oct 08, 2020 03:00
IJMS, Vol. 21, Pages 7407: LINC00885 a Novel Oncogenic Long Non-Coding RNA Associated with Early Stage Breast Cancer Progression International Journal of Molecular Sciences doi: 10.3390/ijms21197407 Authors: Martin C. Abba Romina Canzoneri Agustina Gurruchaga Jaeho Lee Pradeep Tatineni Hyunsuk Kil Ezequiel Lacunza C. Marcelo Aldaz Long intergenic non-protein coding RNA 885 (LINC00885) was identified as significantly upregulated in breast ductal carcinoma in situ...
Thu Oct 08, 2020 03:00
IJNS, Vol. 6, Pages 78: Digital Microfluidics in Newborn Screening for Mucopolysaccharidoses: A Progress Report International Journal of Neonatal Screening doi: 10.3390/ijns6040078 Authors: Jon Washburn David S. Millington Newborn screening (NBS) for mucopolysaccharidosis type I (MPS I, Hurler syndrome) is currently conducted in about two-fifths of the NBS programs in the United States and in a few other countries. Screening is performed by measurement of residual activity of the...
Thu Oct 08, 2020 03:00
IJNS, Vol. 6, Pages 77: Considering Proximal Urea Cycle Disorders in Expanded Newborn Screening International Journal of Neonatal Screening doi: 10.3390/ijns6040077 Authors: Tania Vasquez-Loarte John D. Thompson J. Lawrence Merritt Proximal urea cycle disorders (PUCDs) have adverse outcomes such as intellectual disability and death, which may benefit from newborn screening (NBS) through early detection and prevention with early treatment. Ornithine transcarbamylase deficiency (OTCD)...
Thu Oct 08, 2020 03:00
JCM, Vol. 9, Pages 3227: MiRNAs Regulating Oxidative Stress: A Correlation with Doppler Sonography of Uteroplacental Complex and Clinical State Assessments of Newborns in Fetal Growth Restriction Journal of Clinical Medicine doi: 10.3390/jcm9103227 Authors: Vladislava Gusar Mariya Ganichkina Vitaliy Chagovets Nataliya Kan Gennadiy Sukhikh Overproduction of reactive oxygen species (ROS) and, as a result, uncontrolled oxidative stress (OS) can play a central role in disorders...
Thu Oct 08, 2020 03:00
JCM, Vol. 9, Pages 3225: Risk Perception of COVID-19, Meaning-Based Resources and Psychological Well-Being amongst Healthcare Personnel: The Mediating Role of Coping Journal of Clinical Medicine doi: 10.3390/jcm9103225 Authors: Dariusz Krok Beata Zarzycka The well-being of healthcare personnel during the COVID-19 pandemic depends on the ways in which they perceive the threat posed by the virus, personal resources, and coping abilities. The current study aims to examine the mediating...
Thu Oct 08, 2020 03:00
JCM, Vol. 9, Pages 3224: BCG Vaccine Protection against TB Infection among Children Older than 5 Years in Close Contact with an Infectious Adult TB Case Journal of Clinical Medicine doi: 10.3390/jcm9103224 Authors: Syggelou Spyridis Benetatou Kourkouni Kourlaba Tsagaraki Maritsi Eleftheriou Tsolia The Bacille Calmette–Guérin (BCG) vaccine has been shown to provide considerable protection against miliary or meningeal tuberculosis...
Thu Oct 08, 2020 03:00
JCM, Vol. 9, Pages 3226: Targeting Tumor-Associated Macrophages in Anti-Cancer Therapies: Convincing the Traitors to Do the Right Thing Journal of Clinical Medicine doi: 10.3390/jcm9103226 Authors: Belgiovine Digifico Anfray Ummarino Torres Andón In the last decade, it has been well-established that tumor-infiltrating myeloid cells fuel not only the process of carcinogenesis through cancer-related inflammation mechanisms, but also tumor progression, invasion, and metastasis....
Thu Oct 08, 2020 03:00
JCM, Vol. 9, Pages 3222: Visual and Topographic Improvement with Epithelium-On, Oxygen-Supplemented, Customized Corneal Cross-Linking for Progressive Keratoconus Journal of Clinical Medicine doi: 10.3390/jcm9103222 Authors: Kazutaka Kamiya Shunsuke Kanayama Masahide Takahashi Nobuyuki Shoji Customized cross-linking has been proposed as an alternative to conventional cross-linking in patients with progressive keratoconus, targeting greater flattening of the cone region and improved...
Thu Oct 08, 2020 03:00
JCM, Vol. 9, Pages 3223: Pregnancy Outcomes in Women with Long-Duration Type 1 Diabetes—25 Years of Experience Journal of Clinical Medicine doi: 10.3390/jcm9103223 Authors: Wender-Ozegowska Gutaj Mantaj Kornacki Ozegowski Zawiejska Aims: Our study aimed to examine the pregnancy outcomes (maternal and fetal) concerning different models of antenatal care across a period of over 25 years (1993–2018) in 459 women with type 1 diabetes. Data from patients with...
Thu Oct 08, 2020 03:00
JoF, Vol. 6, Pages 210: Fungus Aspergillus niger Processes Exogenous Zinc Nanoparticles into a Biogenic Oxalate Mineral Journal of Fungi doi: 10.3390/jof6040210 Authors: Martin Šebesta Martin Urík Marek Bujdoš Marek Kolenčík Ivo Vávra Edmund Dobročka Hyunjung Kim Peter Matúš Zinc oxide nanoparticles (ZnO NPs) belong to the most widely used nanoparticles in both commercial products and industrial applications. Hence, they are frequently released into the environment....
Thu Oct 08, 2020 03:00
JoF, Vol. 6, Pages 211: COVID-19-Associated Candidiasis (CAC): An Underestimated Complication in the Absence of Immunological Predispositions? Journal of Fungi doi: 10.3390/jof6040211 Authors: Amir Arastehfar Agostinho Carvalho M. Hong Nguyen Mohammad Taghi Hedayati Mihai G. Netea David S. Perlin Martin Hoenigl The recent global pandemic of COVID-19 has predisposed a relatively high number of patients to acute respiratory distress syndrome (ARDS), which carries a risk...
Thu Oct 08, 2020 03:00
J. Imaging, Vol. 6, Pages 106: Initial Investigations of the Cranial Size and Shape of Adult Eurasian Otters (Lutra lutra) in Great Britain Journal of Imaging doi: 10.3390/jimaging6100106 Authors: Damian J. J. Farnell Chern Khor Wayne Nishio Ayre Zoe Doyle Elizabeth A. Chadwick Three-dimensional (3D) surface scans were carried out in order to determine the shapes of the upper sections of (skeletal) crania of adult Eurasian otters (Lutra lutra) from Great Britain. Landmark...
Thu Oct 08, 2020 03:00
J. Imaging, Vol. 6, Pages 105: Applications of Computational Methods in Biomedical Breast Cancer Imaging Diagnostics: A Review Journal of Imaging doi: 10.3390/jimaging6100105 Authors: Kehinde Aruleba George Obaido Blessing Ogbuokiri Adewale Oluwaseun Fadaka Ashwil Klein Tayo Alex Adekiya Raphael Taiwo Aruleba With the exponential increase in new cases coupled with an increased mortality rate, cancer has ranked as the second most prevalent cause of death in the world....
Thu Oct 08, 2020 03:00
JPM, Vol. 10, Pages 159: Digitized Autism Observation Diagnostic Schedule: Social Interactions beyond the Limits of the Naked Eye Journal of Personalized Medicine doi: 10.3390/jpm10040159 Authors: Harshit Bokadia Richa Rai Elizabeth Barbara Torres The complexity and non-linear dynamics of socio-motor phenomena underlying social interactions are often missed by observation methods that attempt to capture, describe, and rate the exchange in real time. Unknowingly to the rater, socio-motor...
Thu Oct 08, 2020 03:00
JPM, Vol. 10, Pages 157: Spontaneous Rectal Perforation in a Patient with SARS–CoV-2 Infection Journal of Personalized Medicine doi: 10.3390/jpm10040157 Authors: Mauro Giuffrè Alessandro Marco Bozzato Stefano Di Bella Alessandro Agostino Occhipinti Paola Martingano Marco Francesco Maria Cavallaro Roberto Luzzati Fabio Monica Maria Assunta Cova Lory Saveria Crocè Coronavirus disease 2019 (COVID-19) is mostly perceived as a respiratory disease. However, there...
Thu Oct 08, 2020 03:00
JPM, Vol. 10, Pages 158: Towards Accurate Genotype–Phenotype Correlations in the CYP2D6 Gene Journal of Personalized Medicine doi: 10.3390/jpm10040158 Authors: Angel L. Pey Establishing accurate and large-scale genotype–phenotype correlations and predictions of individual response to pharmacological treatments are two of the holy grails of Personalized Medicine. These tasks are challenging and require an integrated knowledge of the complex processes that regulate gene expression...
Thu Oct 08, 2020 03:00
Life, Vol. 10, Pages 235: Approaching Gravity as a Continuum Using the Rat Partial Weight-Bearing Model Life doi: 10.3390/life10100235 Authors: Marie Mortreux Megan E. Rosa-Caldwell For decades, scientists have relied on animals to understand the risks and consequences of space travel. Animals remain key to study the physiological alterations during spaceflight and provide crucial information about microgravity-induced changes. While spaceflights may appear common, they remain costly...
Thu Oct 08, 2020 03:00
Life, Vol. 10, Pages 234: Biochemical Characterization of a Bifunctional Enzyme Constructed by the Fusion of a Glucuronan Lyase and a Chitinase from Trichoderma sp. Life doi: 10.3390/life10100234 Authors: Zeineb Baklouti Cédric Delattre Guillaume Pierre Christine Gardarin Slim Abdelkafi Philippe Michaud Pascal Dubessay Bifunctional enzymes created by the fusion of a glucuronan lyase (TrGL) and a chitinase (ThCHIT42) from Trichoderma sp. have been constructed with the...
Thu Oct 08, 2020 03:00
Membranes, Vol. 10, Pages 276: Performance Evaluation and Kinetic Analysis of Photocatalytic Membrane Reactor in Wastewater Treatment Membranes doi: 10.3390/membranes10100276 Authors: Zeitoun El-Shazly Nosier Elmarghany Salem Taha The objectives of the current study are to assess and compare the performance of a developed photocatalytic membrane reactor (PMR) in treating industrial waste (e.g., organic dye waste) against membrane distillation. The current PMR is...
Thu Oct 08, 2020 03:00
Metabolites, Vol. 10, Pages 399: Running on Empty: A Metabolomics Approach to Investigating Changing Energy Metabolism during Fasted Exercise and Rest Metabolites doi: 10.3390/metabo10100399 Authors: Gavin Blackburn Joshua Hay Christine Skagen Elizabeth Paul Fiona Achcar John Wilson Cameron Best Erin Manson Karl Burgess Michael P. Barrett Jason M. R. Gill Understanding the metabolic processes in energy metabolism, particularly during fasted exercise, is...
Thu Oct 08, 2020 03:00
Metabolites, Vol. 10, Pages 398: Chemical Labeling Assisted Detection and Identification of Short Chain Fatty Acid Esters of Hydroxy Fatty Acid in Rat Colon and Cecum Contents Metabolites doi: 10.3390/metabo10100398 Authors: Siddabasave Gowda B. Gowda Divyavani Gowda Chongsheng Liang Yonghan Li Kentaro Kawakami Satoru Fukiya Atsushi Yokota Hitoshi Chiba Shu-Ping Hui Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are novel endogenous lipids with important...
Thu Oct 08, 2020 03:00
Metabolites, Vol. 10, Pages 397: What’s Past Is Prologue: History of Nonalcoholic Fatty Liver Disease Metabolites doi: 10.3390/metabo10100397 Authors: Giovanni Targher Since the initial descriptions in the early 1980s by Dr. Ludwig et al. and Drs. Schaffner and Thaler, who firstly coined the terms nonalcoholic steatohepatitis (NASH) and nonalcoholic fatty liver disease (NAFLD), this liver disease has become a global health problem worldwide, causing considerable liver-related and extra-hepatic...
Thu Oct 08, 2020 03:00
Microorganisms, Vol. 8, Pages 1552: Isolation and Investigation of Potential Non-Saccharomyces Yeasts to Improve the Volatile Terpene Compounds in Korean Muscat Bailey A Wine Microorganisms doi: 10.3390/microorganisms8101552 Authors: Sae-Byuk Lee Heui-Dong Park The Muscat Bailey A (MBA) grape, one of the most prominent grape cultivars in Korea, contains considerable amounts of monoterpene alcohols that have very low odor thresholds and significantly affect the perception of wine aroma....
Thu Oct 08, 2020 03:00
Microorganisms, Vol. 8, Pages 1550: Seasonal and Nutrient Supplement Responses in Rumen Microbiota Structure and Metabolites of Tropical Rangeland Cattle Microorganisms doi: 10.3390/microorganisms8101550 Authors: Gonzalo Martinez-Fernandez Jinzhen Jiao Jagadish Padmanabha Stuart E. Denman Christopher S. McSweeney This study aimed to characterize the rumen microbiota structure of cattle grazing in tropical rangelands throughout seasons and their responses in rumen ecology...
Thu Oct 08, 2020 03:00
Microorganisms, Vol. 8, Pages 1549: A Mutant of Vibrio parahaemolyticus pirABVP (+) That Carries Binary Toxin Genes but Does Not Cause Acute Hepatopancreatic Necrosis Disease Microorganisms doi: 10.3390/microorganisms8101549 Authors: Luis Fernando Aranguren Caro Hung N. Mai Siddhartha Kanrar Roberto Cruz-Flores Arun K. Dhar Vibrio parahaemolyticus carrying binary toxin genes, pirAB, is one of the etiological agents causing acute hepatopancreatic necrosis disease (AHPND) in...
Thu Oct 08, 2020 03:00
Microorganisms, Vol. 8, Pages 1551: The Effects of Silver Sulfadiazine on Methicillin-Resistant Staphylococcus aureus Biofilms Microorganisms doi: 10.3390/microorganisms8101551 Authors: Yutaka Ueda Motoyasu Miyazaki Kota Mashima Satoshi Takagi Shuuji Hara Hidetoshi Kamimura Shiro Jimi Methicillin-resistant Staphylococcus aureus (MRSA), the most commonly detected drug-resistant microbe in hospitals, adheres to substrates and forms biofilms that are resistant to immunological...
Thu Oct 08, 2020 03:00
Molbank, Vol. 2020, Article M1159: 3,5-Bis((E)-4-methoxybenzylidene)-1-(2-morpholinoethyl)piperidin-4-one Molbank doi: 10.3390/M1159 Authors: Tyas Kuswardani Noval Herfindo Neni Frimayanti Rudi Hendra Adel Zamri The 3,5-bis((E)-4-methoxybenzylidene)-1-(2-morpholinoethyl)piperidin-4-one (3) compound was synthesized by a two-step reaction with 92% yield. The chemical structure of compound 3 was confirmed by IR, NMR, and mass spectrometry. The title compound was screened for...
Thu Oct 08, 2020 03:00
Molecules, Vol. 25, Pages 4591: Magnolol Enhances the Therapeutic Effects of TRAIL through DR5 Upregulation and Downregulation of c-FLIP and Mcl-1 Proteins in Cancer Cells Molecules doi: 10.3390/molecules25194591 Authors: Seon Min Woo Kyoung-jin Min Taeg Kyu Kwon Magnolol is a biologically active compound, isolated from the Chinese herb Magnolia, that regulates antiproliferative, anticancer, antiangiogenic and antimetastatic activities. We found that magnolol sensitizes TRAIL-induced...
Thu Oct 08, 2020 03:00
Molecules, Vol. 25, Pages 4590: Aromadendrin Inhibits T Cell Activation via Regulation of Calcium Influx and NFAT Activity Molecules doi: 10.3390/molecules25194590 Authors: Hyun-Su Lee Gil-Saeng Jeong The objective of this study was to assess the inhibitory effect of the flavonoid aromadendrin on T cell activity to identify a non-cytotoxic immunosuppressive reagent. Conventional and qualitative PCR, MTT assays, flow cytometry and Western blotting were used to evaluate the effect of...
Thu Oct 08, 2020 03:00
Molecules, Vol. 25, Pages 4589: In Vitro Interaction of AB-FUBINACA with Human Cytochrome P450, UDP-Glucuronosyltransferase Enzymes and Drug Transporters Molecules doi: 10.3390/molecules25194589 Authors: Sunjoo Kim Dong Kyun Kim Yongho Shin Ji-Hyeon Jeon Im-Sook Song Hye Suk Lee AB-FUBINACA, a synthetic indazole carboxamide cannabinoid, has been used worldwide as a new psychoactive substance. Because drug abusers take various drugs concomitantly, it is necessary to explore...
Thu Oct 08, 2020 03:00
Molecules, Vol. 25, Pages 4588: Qualitative and Quantitative Analysis of Ukrainian Iris Species: A Fresh Look on Their Antioxidant Content and Biological Activities Molecules doi: 10.3390/molecules25194588 Authors: Olha Mykhailenko Michal Korinek Liudas Ivanauskas Ivan Bezruk Artem Myhal Vilma Petrikaitė Mohamed El-Shazly Guan-Hua Lin Chia-Yi Lin Chia-Hung Yen Bing-Hung Chen Victoriya Georgiyants Tsong-Long Hwang The major groups of antioxidant compounds...
Thu Oct 08, 2020 03:00
Molecules, Vol. 25, Pages 4586: Antiproliferative and Antimigration Activities of Beauvericin Isolated from Isaria sp. on Pancreatic Cancer Cells Molecules doi: 10.3390/molecules25194586 Authors: Hiroaki Yahagi Tadahiro Yahagi Megumi Furukawa Keiichi Matsuzaki This study describes the antiproliferative and antimigration effects of beauvericin from a culture broth of Isaria sp. in human pancreatic cancer cells (PANC-1). Activity-guided fractionation of the EtOAc extract of cultured...
Thu Oct 08, 2020 03:00
Molecules, Vol. 25, Pages 4587: Chemical Composition of 21 Cultivars of Sour Cherry (Prunus cerasus) Fruit Cultivated in Poland Molecules doi: 10.3390/molecules25194587 Authors: Anna Sokół-Łętowska Alicja Z. Kucharska Grzegorz Hodun Marta Gołba Sour cherry (Prunus cerasus L.) is a very important fruit crop for producers as well as consumers. To obtain information on sour cherry fruit, we determined the sugar and organic acid composition and phenolic compound contents of twenty-one...
Thu Oct 08, 2020 03:00
Molecules, Vol. 25, Pages 4584: Synthesis, Biological Evaluation and Stability Studies of Some Novel Aza-Acridine Aminoderivatives Molecules doi: 10.3390/molecules25194584 Authors: Maria Karelou Vasileios Kourafalos Athanasia P. Tragomalou Panagiotis Marakos Nicole Pouli Ourania E. Tsitsilonis Evangelos Gikas Ioannis K. Kostakis Several new amino-substituted aza-acridine derivatives bearing a basic side chain have been designed and synthesized. The antiproliferative...
Thu Oct 08, 2020 03:00
Molecules, Vol. 25, Pages 4585: Initial In Vitro and In Vivo Evaluation of a Novel CCK2R Targeting Peptide Analog Labeled with Lutetium-177 Molecules doi: 10.3390/molecules25194585 Authors: Anton Amadeus Hörmann Maximilian Klingler Maliheh Rezaeianpour Nikolas Hörmann Ronald Gust Soraya Shahhosseini Elisabeth von Guggenberg Targeting of cholecystokinin-2 receptor (CCK2R) expressing tumors using radiolabeled minigastrin (MG) analogs is hampered by rapid digestion of...
Thu Oct 08, 2020 03:00
Nutrients, Vol. 12, Pages 3075: Effects of Nutritional Interventions in the Control of Musculoskeletal Pain: An Integrative Review Nutrients doi: 10.3390/nu12103075 Authors: Carolina Rodrigues Mendonça Matias Noll Maria Clara Rezende Castro Erika Aparecida Silveira Food consumption has significant positive effects on an individual’s health status, including the reduction of symptoms associated with musculoskeletal pain. However, specific food groups indicated for the...
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Nutrients, Vol. 12, Pages 3074: Low Serum Magnesium is Associated with Incident Dementia in the ARIC-NCS Cohort Nutrients doi: 10.3390/nu12103074 Authors: Aniqa B. Alam Pamela L. Lutsey Rebecca F. Gottesman Adrienne Tin Alvaro Alonso Higher serum magnesium is associated with lower risk of multiple morbidities, including diabetes, stroke, and atrial fibrillation, but its potential neuroprotective properties have also been gaining traction in cognitive function and decline...
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Nutrients, Vol. 12, Pages 3071: The Effect of Exercise on Nutritional Status and Body Composition in Hemodialysis: A Systematic Review Nutrients doi: 10.3390/nu12103071 Authors: Dimitra Rafailia Bakaloudi Antonios Siargkas Kalliopi Anna Poulia Evangelia Dounousi Michail Chourdakis Chronic kidney disease (CKD) is associated with aggravating factors which can affect both body composition and nutritional status. The purpose of the present systematic review was to investigate...
Thu Oct 08, 2020 03:00
Nutrients, Vol. 12, Pages 3073: What was First, Obesity or Inflammatory Bowel Disease? What Does the Gut Microbiota Have to Do with It? Nutrients doi: 10.3390/nu12103073 Authors: Sara Jarmakiewicz-Czaja Aneta Sokal Rafał Filip A sedentary lifestyle and inadequate nutrition often leads to disturbances in intestinal homeostasis, which may predispose people to excess body weight and metabolic syndrome. Obesity is frequently observed in patients with inflammatory bowel diseases (IBD),...
Thu Oct 08, 2020 03:00
Nutrients, Vol. 12, Pages 3070: The Interactive Effect of High Doses of Chromium(III) and Different Iron(III) Levels on the Carbohydrate Status, Lipid Profile, and Selected Biochemical Parameters in Female Wistar Rats Nutrients doi: 10.3390/nu12103070 Authors: Halina Zofia Staniek Ewelina Król Rafał Wojciech Wójciak The aim of the study was to evaluate the main and interactive effects of chromium(III) propionate complex (Cr3) supplementation and different iron supply on the carbohydrate...
Thu Oct 08, 2020 03:00
Nutrients, Vol. 12, Pages 3072: Epigallocatechin-3-Gallate Reduces Visceral Adiposity Partly through the Regulation of Beclin1-Dependent Autophagy in White Adipose Tissues Nutrients doi: 10.3390/nu12103072 Authors: Cheoljun Choi Hyun-Doo Song Yeonho Son Yoon Keun Cho Sang-Yeop Ahn Young-Suk Jung Young Cheol Yoon Sung Won Kwon Yun-Hee Lee Epigallocatechin-3-gallate (EGCG) is a primary bioactive phytochemical in green tea. Its therapeutic potential in metabolic...
Thu Oct 08, 2020 03:00
Nutrients, Vol. 12, Pages 3069: Effect of Added Sugar on the Consumption of A Lipid-Based Nutrient Supplement Among 7–24-Month-Old Children Nutrients doi: 10.3390/nu12103069 Authors: Harriet Okronipa Amado D. Quezada-Sánchez Susan L. Johnson Cloe Rawlinson Selene Pacheco-Miranda Mónica Venosa López Wendy Gonzalez Navarrete Anabelle Bonvecchio Arenas Small-quantity lipid-based nutrient supplements (SQ-LNS) could help prevent malnutrition. Our primary objective was...
Thu Oct 08, 2020 03:00
Nutrients, Vol. 12, Pages 3068: Oligo-Fucoidan Improves Diabetes-Induced Renal Fibrosis via Activation of Sirt-1, GLP-1R, and Nrf2/HO-1: An In Vitro and In Vivo Study Nutrients doi: 10.3390/nu12103068 Authors: Wen-Chun Yu Ren-Yeong Huang Tz-Chong Chou Fucoidan extracted from brown algae has multiple beneficial functions. In this study, we investigated the effects of low-molecular-weight fucoidan (oligo-FO) on renal fibrosis under in vitro and in vivo diabetic conditions, and its...
Thu Oct 08, 2020 03:00
Nutrients, Vol. 12, Pages 3066: Circulating microRNAs in Breast Milk and Their Potential Impact on the Infant Nutrients doi: 10.3390/nu12103066 Authors: Elena Carrillo-Lozano Fernando Sebastián-Valles Carolina Knott-Torcal MicroRNAs (MiRNAs) are small RNA molecules that can exert regulatory functions in gene expression. MiRNAs have been identified in diverse tissues and biological fluids, both in the context of health and disease. Breastfeeding has been widely recognized for its...
Thu Oct 08, 2020 03:00
Nutrients, Vol. 12, Pages 3067: Wolffia globosa–Mankai Plant-Based Protein Contains Bioactive Vitamin B12 and Is Well Absorbed in Humans Nutrients doi: 10.3390/nu12103067 Authors: Ilan Sela Anat Yaskolka Meir Alexander Brandis Rosa Krajmalnik-Brown Lydia Zeibich Debbie Chang Blake Dirks Gal Tsaban Alon Kaplan Ehud Rinott Hila Zelicha Shira Arinos Uta Ceglarek Berend Isermann Miri Lapidot Ralph Green Iris Shai Background: Rare plants that...
Thu Oct 08, 2020 03:00
Pathogens, Vol. 9, Pages 825: Bacterial Lipoteichoic Acid Attenuates Toll-Like Receptor Dependent Dendritic Cells Activation and Inflammatory Response Pathogens doi: 10.3390/pathogens9100825 Authors: Suguru Saito Alato Okuno Duo-Yao Cao Zhenzi Peng Hui-Ya Wu Shu-Hui Lin Toll-like receptor (TLR) signaling is an indispensable factor in immune cells activation. Many TLR ligands have been identified, and were characterized the immunological functions such as inflammatory cytokine...
Thu Oct 08, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 296: A Photocleavable Contrast Agent for Light-Responsive MRI Pharmaceuticals doi: 10.3390/ph13100296 Authors: Friederike Reeßing Sèvrin E. M. Huijsse Rudi A. J. O. Dierckx Ben L. Feringa Ronald J.H. Borra Wiktor Szymański Thanks to its innocuousness and high spatiotemporal resolution, light is used in several established and emerging applications in biomedicine. Among them is the modulation of magnetic resonance imaging (MRI) contrast agents’...
Thu Oct 08, 2020 03:00
Pharmacy, Vol. 8, Pages 185: Over-The-Counter Codeine: Can Community Pharmacy Staff Nudge Customers into Its Safe and Appropriate Use? Pharmacy doi: 10.3390/pharmacy8040185 Authors: Sapana Mody Charlotte L. Kirkdale Tracey Thornley Aimi Dickinson Anthony J. Avery Roger Knaggs Sarah Rann Ruth Bastable The misuse of opioids, including codeine which is sold over-the-counter (OTC) in United Kingdom (UK) community pharmacies, is a growing public health concern. An educational...
Thu Oct 08, 2020 03:00
Pharmacy, Vol. 8, Pages 184: Check-In: An Educational Activity to Address Well-Being and Burnout among Pharmacy Students Pharmacy doi: 10.3390/pharmacy8040184 Authors: Heidi V.J. Fernandes Cynthia Richard Kaitlin Bynkoski Becky Ewan Sherilyn K.D. Houle Background: Chronic workplace stress that has not been adequately managed can result in burnout. Healthcare providers; including pharmacists, may be particularly susceptible to this phenomenon, prompting the School of Pharmacy...
Thu Oct 08, 2020 03:00
Plants, Vol. 9, Pages 1326: Root System Architecture, Copper Uptake and Tissue Distribution in Soybean (Glycine max (L.) Merr.) Grown in Copper Oxide Nanoparticle (CuONP)-Amended Soil and Implications for Human Nutrition Plants doi: 10.3390/plants9101326 Authors: Elham Yusefi-Tanha Sina Fallah Ali Rostamnejadi Lok Raj Pokhrel Understanding the potential uptake and biodistribution of engineered nanoparticles (ENPs) in soil-grown plants is imperative for realistic toxicity and...
Thu Oct 08, 2020 03:00
Religions, Vol. 11, Pages 509: The Active Life and the Contemplative Life in St. John of the Cross: The Mixed Life in the Teresian Carmelite Tradition Religions doi: 10.3390/rel11100509 Authors: Cristóbal Serrán-Pagán y Fuentes The prophetic and the mystical are two key theological concepts in St. John of the Cross. The aim of this article is precisely to shed light on the essential role that St. John of the Cross played in the history of Christianity by acknowledging the prophetic and...
Thu Oct 08, 2020 03:00
Safety, Vol. 6, Pages 45: Road Safety Analysis of High-Risk Roads: Case Study in Baja California, México Safety doi: 10.3390/safety6040045 Authors: Marco Montoya-Alcaraz Alejandro Mungaray-Moctezuma Julio Calderón-Ramírez Leonel García Cynthia Martinez-Lazcano The objective of this research is to develop a useful procedure to assess and identify risks that promote accidents by road users, with the vision of improving safety through the implementation and technical employment...
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Toxins, Vol. 12, Pages 649: Cross-Reactive Carbohydrate Determinant in Apis mellifera, Solenopsis invicta and Polybia paulista Venoms: Identification of Allergic Sensitization and Cross-Reactivity Toxins doi: 10.3390/toxins12100649 Authors: Débora Moitinho Abram Luís Gustavo Romani Fernandes Amilcar Perez-Riverol Márcia Regina Brochetto-Braga Ricardo de Lima Zollner Allergic reactions to Hymenoptera venom, which could lead to systemic and even fatal symptoms, is characterized...
Thu Oct 08, 2020 03:00
Toxins, Vol. 12, Pages 650: Molecular Characterization of Clostridium perfringens Strains Isolated in Italy Toxins doi: 10.3390/toxins12100650 Authors: Katia Forti Laura Ferroni Martina Pellegrini Deborah Cruciani Antonio De Giuseppe Silvia Crotti Paola Papa Carmen Maresca Giulio Severi Maria Luisa Marenzoni Monica Cagiola Clostridium (C.) perfringens is the causative agent of several diseases and enteric infections in animals and humans. The pathogenicity...
Thu Oct 08, 2020 03:00
Toxins, Vol. 12, Pages 648: Mycotoxins in Ethiopia: A Review on Prevalence, Economic and Health Impacts Toxins doi: 10.3390/toxins12100648 Authors: Firew Tafesse Mamo Birhan Addisie Abate Kassahun Tesfaye Chengrong Nie Gang Wang Yang Liu Mycotoxigenic fungi and their toxins are a global concern, causing huge economic and health impacts in developing countries such as Ethiopia, where the mycotoxin control system is inadequate. This work aimed to review the occurrences of...
Thu Oct 08, 2020 03:00
Toxins, Vol. 12, Pages 647: Rearrangement of N-Terminal α-Helices of Bacillus thuringiensis Cry1Ab Toxin Essential for Oligomer Assembly and Toxicity Toxins doi: 10.3390/toxins12100647 Authors: Sabino Pacheco Jean Piere Jesus Quiliche Isabel Gómez Jorge Sánchez Mario Soberón Alejandra Bravo Cry proteins produced by Bacillus thuringiensis are pore-forming toxins that disrupt the membrane integrity of insect midgut cells. The structure of such pore is unknown, but it has...
Thu Oct 08, 2020 03:00
Vaccines, Vol. 8, Pages 591: Evolutionary Analysis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reveals Genomic Divergence with Implications for Universal Vaccine Efficacy Vaccines doi: 10.3390/vaccines8040591 Authors: Nanda Kumar Yellapu Shachi Patel Bo Zhang Richard Meier Lisa Neums Dong Pei Qing Xia Duncan Rotich Rosalyn C. Zimmermann Emily Nissen Shelby Bell-Glenn Whitney Shae Jinxiang Hu Prabhakar Chalise Lynn Chollet-Hinton...
Thu Oct 08, 2020 03:00
Vaccines, Vol. 8, Pages 590: Addressing Parental Vaccine Hesitancy towards Childhood Vaccines in the United States: A Systematic Literature Review of Communication Interventions and Strategies Vaccines doi: 10.3390/vaccines8040590 Authors: Olivia Olson Corinne Berry Nirbhay Kumar Parental vaccine hesitancy is becoming an increasingly important public health concern in the United States. In March 2020, an assessment of the latest CDC National Immunization Survey data found that...
Thu Oct 08, 2020 03:00
Viruses, Vol. 12, Pages 1142: A Diverse Virome of Leafroll-Infected Grapevine Unveiled by dsRNA Sequencing Viruses doi: 10.3390/v12101142 Authors: Mamadou L. Fall Dong Xu Pierre Lemoyne Issam E. Ben Moussa Carole Beaulieu Odile Carisse Quebec is the third-largest wine grape producing province in Canada, and the industry is constantly expanding. Traditionally, 90% of the grapevine cultivars grown in Quebec were winter hardy and largely dominated by interspecific hybrid...
Thu Oct 08, 2020 03:00
Viruses, Vol. 12, Pages 1140: Autoreactivity of Broadly Neutralizing Influenza Human Antibodies to Human Tissues and Human Proteins Viruses doi: 10.3390/v12101140 Authors: Surender Khurana Megan Hahn Laura Klenow Hana Golding Broadly neutralizing monoclonal antibodies (bNAbs) against conserved domains in the influenza hemagglutinin are in clinical trials. Several next generation influenza vaccines designed to elicit such bNAbs are also in clinical development. One of the common...
Thu Oct 08, 2020 03:00
Viruses, Vol. 12, Pages 1141: In Vitro and In Vivo Antiviral Activity of Gingerenone A on Influenza A Virus Is Mediated by Targeting Janus Kinase 2 Viruses doi: 10.3390/v12101141 Authors: Jiongjiong Wang Richard A. Prinz Xiufan Liu Xiulong Xu Janus kinase (JAK) inhibitors have been developed as novel immunomodulatory drugs and primarily used for treating rheumatoid arthritis and other inflammatory diseases. Recent studies have suggested that this category of anti-inflammatory...
Thu Oct 08, 2020 03:00
Viruses, Vol. 12, Pages 1139: In Vitro Combinations of Baloxavir Acid and Other Inhibitors against Seasonal Influenza A Viruses Viruses doi: 10.3390/v12101139 Authors: Liva Checkmahomed Blandine Padey Andrés Pizzorno Olivier Terrier Manuel Rosa-Calatrava Yacine Abed Mariana Baz Guy Boivin Two antiviral classes, the neuraminidase inhibitors (NAIs) and polymerase inhibitors (baloxavir marboxil and favipiravir) can be used to prevent and treat influenza infections during...
Thu Oct 08, 2020 03:00
Viruses, Vol. 12, Pages 1138: Characterization of Novel Lytic Bacteriophages of Achromobacter marplantensis Isolated from a Pneumonia Patient Viruses doi: 10.3390/v12101138 Authors: Hiu Tat Chan Heng Ku Ying Ping Low Teagan Brown Steven Batinovic Mwila Kabwe Steve Petrovski Joseph Tucci Achromobacter spp. are becoming increasingly associated with lung infections in patients suffering from cystic fibrosis (CF). A. marplatensis, which is closely related to A. xylosoxidans,...
Thu Oct 08, 2020 03:00
Water, Vol. 12, Pages 2795: Socio-Hydrological Modelling to Assess Reliability of an Urban Water System under Formal-Informal Supply Dynamics Water doi: 10.3390/w12102795 Authors: Rakhshinda Bano Mehdi Khiadani Steven Burian Increasing water scarcity in developing world cities combined with poor performance of water supply systems has led to an increasing reliance on informal water supply systems. Although the availability of informal supply is provides a coping mechanism that...
Thu Oct 08, 2020 03:00
Water, Vol. 12, Pages 2794: Dynamic Characteristics of Bubble Collapse near the Liquid–Liquid Interface Water doi: 10.3390/w12102794 Authors: Zhaoqin Yin Zemin Huang Chengxu Tu Xiaoyan Gao Fubing Bao Bubble collapse near the liquid–liquid interface was experimentally studied in this paper, and the dynamic evolution of a laser-induced bubble (generation, expansion, and collapse) and the liquid–liquid interface (dent and rebound) were captured by a high-speed...
Thu Oct 08, 2020 03:00
Water, Vol. 12, Pages 2793: Modeling the Influence of Public Risk Perceptions on the Adoption of Green Stormwater Infrastructure: An Application of Bayesian Belief Networks Versus Logistic Regressions on A Statewide Survey of Households in Vermont Water doi: 10.3390/w12102793 Authors: Qing Ren Asim Zia Donna M. Rizzo Nancy Mathews There is growing environmental psychology and behavior literature with mixed empirical evidence about the influence of public risk perceptions on...
Thu Oct 08, 2020 03:00
Water, Vol. 12, Pages 2792: Hydrogeochemical Characteristics and Groundwater Quality Evaluation Based on Multivariate Statistical Analysis Water doi: 10.3390/w12102792 Authors: Yunxu Chai Changlai Xiao Mingqian Li Xiujuan Liang Hydrogeochemical research and water quality evaluation are an important part of groundwater development and management projects in Dehui City, Jilin Province, China. We collected 217 groundwater samples in the study area and used two multivariate statistical...
Thu Oct 08, 2020 03:00
Water, Vol. 12, Pages 2790: Expansion and Headloss Dependencies for Flowrate and Fluidization during Backwashing of Sand, Anthracite and Filtralite® Expanded Aluminosilicate Filters Water doi: 10.3390/w12102790 Authors: Jaran Raymond Wood Tone Storbråten Timo Neubauer The backwash expansion rates and headloss evolution of single- and dual-media granular filters of Filtralite® expanded aluminosilicate clay were compared with fine and coarser sand, as well as anthracite....
Thu Oct 08, 2020 03:00
Water, Vol. 12, Pages 2791: Contrasting Water Use Strategies of Tamarix ramosissima in Different Habitats in the Northwest of Loess Plateau, China Water doi: 10.3390/w12102791 Authors: Pengyan Su Mingjun Zhang Deye Qu Jiaxin Wang Yu Zhang Xuyang Yao Hanyu Xiao As a species for ecological restoration in northern China, Tamarix ramosissima plays an important role in river protection, flood control, regional climate regulation, and landscape construction with vegetation....
Thu Oct 08, 2020 03:00
Water, Vol. 12, Pages 2788: Addressing Challenges of Urban Water Management in Chinese Sponge Cities via Nature-Based Solutions Water doi: 10.3390/w12102788 Authors: Yunfei Qi Faith Ka Shun Chan Colin Thorne Emily O’Donnell Carlotta Quagliolo Elena Comino Alessandro Pezzoli Lei Li James Griffiths Yanfang Sang Meili Feng Urban flooding has become a serious issue in most Chinese cities due to rapid urbanization and extreme weather, as evidenced by severe events...
Thu Oct 08, 2020 03:00
Water, Vol. 12, Pages 2789: The Water-Saving Strategies Assessment (WSSA) Framework: An Application for the Urmia Lake Restoration Program Water doi: 10.3390/w12102789 Authors: Somayeh Shadkam Pieter van Oel Pavel Kabat Amin Roozbahani Fulco Ludwig Increases in water demand often result in unsustainable water use, leaving insufficient amounts of water for the environment. Therefore, water-saving strategies have been introduced to the environmental policy agenda in many (semi)-arid...
Thu Oct 08, 2020 03:00
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