Response Letter to the Editor from Dorin et al.: "Prevention of Adrenal Crisis: Cortisol Response to Major Stress Compared to Stress Dose Hydrocortisone Delivery". J Clin Endocrinol Metab. 2020 Oct 08;: Authors: Prete A, Taylor AE, Bancos I, Smith DJ, Foster MA, Kohler S, Fazal-Sanderson V, Komninos J, O'Neil DM, Vassiliadi DA, Mowatt CJ, Mihai R, Fallowfield JL, Annane D, Lord JM, Keevil BG, Wass JAH, Karavitaki N, Arlt W PMID: 33027808 [PubMed - as...
Thu Oct 08, 2020 16:19
Letter to the Editor from Dorin, et al: "Prevention of Adrenal Crisis: Cortisol Responses to Major Stress Compared to Stress Dose Hydrocortisone Delivery". J Clin Endocrinol Metab. 2020 Oct 08;: Authors: Dorin RI, Urban Iii FK, Qualls CR PMID: 33027807 [PubMed - as supplied by publisher]
Thu Oct 08, 2020 16:19
Mini-Invasive Endoscopic Approaches to the Maxillary Sinus Floor: A Comparative Anatomical Study. Am J Rhinol Allergy. 2020 Oct 06;:1945892420964096 Authors: Felisati E, Saibene AM, Borloni R, Prades JM, Felisati G Abstract BACKGROUND: While middle antrostomy (MA) is the most common approach to the maxillary sinus (MS), it is known for not allowing to fully inspect the whole MS, especially in its inferior and anterior portions. To overcome...
Thu Oct 08, 2020 16:14
CD9 expression in vascular aging and atherosclerosis. Histol Histopathol. 2020 Oct 07;:18268 Authors: Kim JR, Choi JH Abstract CD9 is a transmembrane glycoprotein belonging to the tetraspanin family. CD9 expression has been reported to be associated with cellular signaling, cell adhesion, cell migration, and tumor related processes. The aim of this study was to examine the immunohistochemical expression of CD9 in vascular senescence and atherosclerosis....
Thu Oct 08, 2020 16:12
Conditions: Ovarian Cancer; Bladder Cancer; Non Small Cell Lung Cancer; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Cancer; Castration Resistant Prostate CancerInterventions: Drug: INCB106385; Drug: INCMGA00012Sponsor: Incyte CorporationNot yet recruiting
Thu Oct 08, 2020 16:05
Condition: Thyroid NoduleIntervention: Procedure: thyroidectomySponsor: Mahmoud FahdNot yet recruiting
Thu Oct 08, 2020 16:05
Conditions: Human Papillomavirus-Related Carcinoma; Oropharyngeal CancerIntervention: Radiation: Hypofractionated intensity modulated radiotherapySponsor: University of Texas Southwestern Medical CenterNot yet recruiting
Thu Oct 08, 2020 16:05
Covid-19, SARS -CoV-2, Origin, transmission and treatment aspects, a brief review. Infect Disord Drug Targets. 2020 Oct 06;: Authors: Nawaz S Abstract The emergence of severe acute respiratory syndrome (SARS) in Wuhan (china) named as corona virus disease 19(covid-19) caused by the novel corona virus SARS-CoV-2 has caused hundreds of thousands of mortalities across the world ,while the mortality rate is in millions, leading it to be declared...
Thu Oct 08, 2020 16:03
Cerebrospinal Fluid Leak After Septoplasty in Crouzon Syndrome. J Craniofac Surg. 2020 Oct 06;: Authors: Demir B, Abuzaid G, Binnetoglu A Abstract Crouzon syndrome presents with craniofacial deformities due to early fusion of cranial sutures. Deviation of the nasal septum could be seen clinically in Crouzon syndrome. Cerebrospinal fluid leaks (CSF) after septoplasty are extremely rare and typically present with simple rhinorrhea, meningitis,...
Thu Oct 08, 2020 16:01
The algorithm for diagnosis and management of intracranial hypotension with coma: Report of two cases. Surg Neurol Int. 2020;11:267 Authors: Arai S, Takai K, Taniguchi M Abstract Background: Spontaneous intracranial hypotension (SIH) is caused by spontaneous cerebrospinal fluid (CSF) leaks that can be treated in most cases with an epidural blood patch (EBP). However, some patients, who develop severe brain sagging, can neurologically deteriorate,...
Thu Oct 08, 2020 16:01
Publication date: Available online 7 October 2020Source: Behavioural Brain ResearchAuthor(s): Jelena Petrovic, Ljiljana Radovanovic, Jasna Saponjic
Thu Oct 08, 2020 15:52
Accessing care in multidisciplinary pain treatment facilities continues to be a challenge in Canada.
Accessing care in multidisciplinary pain treatment facilities continues to be a challenge in Canada. Reg Anesth Pain Med. 2020 Oct 06;: Authors: Choinière M, Peng P, Gilron I, Buckley N, Williamson O, Janelle-Montcalm A, Baerg K, Boulanger A, Di Renna T, Finley GA, Intrater H, Lau B, Pereira J Abstract BACKGROUND: Multidisciplinary pain treatment facilities (MPTFs) are considered the optimal settings for the management of chronic pain...
Thu Oct 08, 2020 15:50
Self-reported disposal of leftover opioids among US adults 50-80. Reg Anesth Pain Med. 2020 Oct 06;: Authors: Harbaugh CM, Malani P, Solway E, Kirch M, Singer D, Englesbe MJ, Brummett CM, Waljee JF Abstract OBJECTIVE: To test the association between self-reported opioid disposal education and self-reported disposal of leftover opioids among older adults. DESIGN: Web-based survey from the National Poll on Healthy Aging (March...
Thu Oct 08, 2020 15:50
Evaluating the spread of costoclavicular brachial plexus block: an anatomical study. Reg Anesth Pain Med. 2020 Oct 06;: Authors: Koyyalamudi V, Langley NR, Harbell MW, Kraus MB, Craner RC, Seamans DP Abstract BACKGROUND AND OBJECTIVES: The costoclavicular brachial plexus block is performed deep and posterior to the midpoint of the clavicle. There are limited data evaluating the spread of the costoclavicular brachial plexus block. We performed...
Thu Oct 08, 2020 15:50
Objective: To evaluate the efficacy of outcomes received by newly implanted cochlear implant recipients when an outcomes-driven, computer-assisted approach to cochlear implantation fitting was used. This approach, referred to as “Fitting to Outcome eXpert,” or FOX, was developed by Otoconsult in Antwerp, Belgium. Design: Thirty-one newly implanted subjects participated in a nonrandomized, single-subject, repeated measures design that involved a within-subject comparison of preoperative and...
Tue Oct 06, 2020 03:00
Objectives: We investigated the impact of both intrinsic and extrinsic cognitive demands on auditory and secondary task performance in older adults with normal hearing (NH) and adults using hearing aids (HAs) in an ecologically relevant listening environment. Design: Fifteen adults with NH and 15 adults using HAs (60 to 72 years of age) were recruited to perform the “Audiovisual True-to-Life Assessment of Auditory Rehabilitation”-paradigm (AVATAR), which combines an auditory-visual speech-in-noise...
Tue Oct 06, 2020 03:00
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Thu Oct 01, 2020 03:00
Measuring progress against cancer in the Azores, Portugal: Incidence, survival, and mortality trends and projections to 2025. Cancer Epidemiol. 2020 Oct 04;69:101810 Authors: Forjaz G, Chen HS, Howlader N, Rego R, Rodrigues V, Mariotto AB Abstract BACKGROUND: Measuring progress against cancer is more accurate when trends in incidence, survival, and mortality are interpreted simultaneously. Our study aims to analyze how these key metrics have...
Thu Oct 08, 2020 15:39
Patients with vertigo/dizziness of unknown origin during follow-ups by general otolaryngologists at outpatient town clinic. Auris Nasus Larynx. 2020 Oct 03;: Authors: Nishikawa D, Wada Y, Shiozaki T, Shugyo M, Ito T, Ota I, Kitahara T Abstract OBJECTIVES: The purpose of this study was to access the contribution of vertigo/dizziness-related patients' interview and examinations during short-term hospitalization in determining the accurate final...
Thu Oct 08, 2020 15:39
Rheumatoide Arthritis des Cricoarytenoid-Gelenks: Wichtige Differenzialdiagnose bei unklaren Raumforderungen des Larynx. Laryngorhinootologie. 2020 04;99(4):237-238 Authors: Billich C, Schwab B PMID: 32314337 [PubMed - indexed for MEDLINE]
Thu Oct 08, 2020 15:39
Stimmlippenrandödem. Laryngorhinootologie. 2020 04;99(4):212-213 Authors: PMID: 32314334 [PubMed - indexed for MEDLINE]
Thu Oct 08, 2020 15:39
Frequency of S492R mutations in the epidermal growth factor receptor: analysis of plasma DNA from patients with metastatic colorectal cancer treated with panitumumab or cetuximab monotherapy. Cancer Biol Ther. 2020 Oct 07;:1-8 Authors: Price T, Ang A, Boedigheimer M, Kim TW, Li J, Cascinu S, Ruff P, Satya Suresh A, Thomas A, Tjulandin S, Peeters M Abstract BACKGROUND: Antibodies against epidermal growth factor receptor (EGFR), panitumumab,...
Thu Oct 08, 2020 15:35
miR-221-3p promotes hepatocellular carcinogenesis by downregulating O6-methylguanine-DNA methyltransferase. Cancer Biol Ther. 2020 Oct 06;:1-12 Authors: Chen Z, Xiang B, Qi L, Zhu S, Li L Abstract This study aimed to investigate the influence of miR-221-3p and O6-methylguanine-DNA methyltransferase (MGMT) interaction in human hepatocellular carcinoma (HCC), thereby revealing a novel molecular mechanism of hepatic carcinogenesis involving miR-221-3p...
Thu Oct 08, 2020 15:35
In March 2020, when there were 30,000 confirmed Covid-19 cases in the United States, one of us wrote about the pandemic’s effects on undocumented immigrants. By August, there were about 50,000 new U.S. cases per day, and we had spent several months caring for patients with Covid-19. Today,…
Wed Oct 07, 2020 03:00
"Have you heard about Covid toes?" My wife, while working through her clinical notes from her pediatrics practice that day, asked the question with a tone of resignation. I hadn’t, but I quickly searched the Web and found a number of reports of rashes on the toes of children infected with…
Wed Oct 07, 2020 03:00
Over the past two decades, emerging coronaviruses (CoVs) have caused three major outbreaks — severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and coronavirus disease 2019 (Covid-19). Since MERS was reported in Saudi Arabia in 2012, at least 2494 cases and 858…
Wed Oct 07, 2020 03:00
As researchers who have long experience with HIV/AIDS prevention, vaccines, and therapies, some of whom also have experience with Ebola, we believe it is critical to build the response to the Covid-19 pandemic on lessons from the HIV pandemic and recent Ebola outbreaks. First and foremost, those…
Wed Oct 07, 2020 03:00
332 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/10/08PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Oct 08, 2020 15:09
Partial high frequency nerve block decreases neuropathic signaling following chronic sciatic nerve constriction injury. J Neural Eng. 2020 Oct 07;: Authors: Dewberry LS, Dru A, Gravenstine M, Nguyen B, Anderson J, Vaziri S, Hoh D, Allen K, Otto KJ Abstract OBJECTIVE: High frequency (HF) block can quickly and reversibly stop nerve conduction. We hypothesized HF block at the sciatic nerve would minimize nociception by preventing neuropathic signals...
Thu Oct 08, 2020 15:05
Uterine inversion may cause massive hemorrhage, resulting in maternal deterioration and death. Replacement of the inverted uterus must be performed as soon as possible. As time passes, the inverted uterus beco...
Thu Oct 08, 2020 03:00
Pancreaticogastrostomy for pancreatic body cystic neoplasms: An organ-sparing approach. Int J Surg Case Rep. 2020;76:153-155 Authors: Orhan O, Carkman S, Erginoz E, Ozcelik MF Abstract Introduction: Surgical management of pancreatic cysts differ according to the specific location of the cyst on the pancreas. Cysts located on the pancreatic head require a radical procedure such as pancreaticoduodenectomy (Whipple procedure). Cysts of the pancreatic...
Thu Oct 08, 2020 14:58
Positive predictive value for diffusion-weighted magnetic resonance imaging in pediatric cholesteatoma: A retrospective study. Int J Pediatr Otorhinolaryngol. 2020 Sep 30;139:110416 Authors: Hervochon R, Elmaleh-Berges M, Francois M, Marhic A, Bahakim A, Teissier N, Abbeele TVD Abstract OBJECTIVES: The aims of this study were first to calculate the Positive Predictive Value (PPV) of DW-MRI to detect cholesteatoma and then to analyze false positives....
Thu Oct 08, 2020 14:58
Validation of the Mandarin versions of CAP and SIR. Int J Pediatr Otorhinolaryngol. 2020 Oct 01;139:110413 Authors: Wang L, Shen M, Liang W, Dao W, Zhou L, Zhu M Abstract OBJECTIVES: The present study aims to develop the Mandarin versions of Categories of Auditory Performance (CAP) and Speech Intelligibility of Rating (SIR), verify their reliability and validity, and establish standardized values of the Mandarin CAP and SIR. In doing that it...
Thu Oct 08, 2020 14:58
Voice-Related Quality of Life Is Associated with Postoperative Change in Subglottic Stenosis. Laryngoscope. 2020 Oct 07;: Authors: Schuman AD, Neevel A, Morrison RJ, Hogikyan ND, Kupfer RA Abstract OBJECTIVES: To characterize the impact of subglottic stenosis (SGS) on voice-related quality of life (V-RQOL) and quantify the effect of treatment on voice outcomes. STUDY DESIGN: Case series. METHODS: Retrospective review of SGS...
Thu Oct 08, 2020 14:44
Simultaneous dysphagia and stridor: an unreported presentation of hypocalcaemia. J Surg Case Rep. 2020 Sep;2020(9):rjaa317 Authors: Thomas C, Bhamra N, Darr A, Amlani A, Murphy J Abstract Hypocalcaemia is a well-recognized complication of total thyroidectomy surgery. Patients who develop post-operative hypocalcaemia often report symptoms of neuromuscular instability including peripheral numbness and/or tingling. In severe cases, larygospasm...
Thu Oct 08, 2020 14:44
Abstract Genomic imprinting results in parent‐of‐origin dependent gene expression biased towards either the maternally‐ or paternally‐derived allele at the imprinted locus. The kinship theory of genomic imprinting argues that this unusual expression pattern is a manifestation of intra‐genomic conflict between the maternally‐ and paternally‐derived halves of the genome that arises because they are not equally related to the genomes of social partners. The theory thus predicts that imprinting may...
Thu Oct 08, 2020 13:16
24 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/10/08PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Oct 08, 2020 14:38
24 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/10/08PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Oct 08, 2020 13:38
Investigation of the serum vitamin D level in infants followed up with the diagnosis of laryngomalacia: a case-control study. Eur Arch Otorhinolaryngol. 2020 Oct 07;: Authors: Bozkurt HB, Çelik M Abstract OBJECTIVE: The possible etiological relationship of the vitamin D with laryngomalacia is unclear. The aim of the study was to demonstrate the relationship between laryngomalacia and vitamin D levels. METHODS: Twenty-three non-syndromic...
Thu Oct 08, 2020 14:34
Patient-reported factors that influence the vestibular schwannoma treatment decision: a qualitative study. Eur Arch Otorhinolaryngol. 2020 Oct 07;: Authors: Neve OM, Soulier G, Hendriksma M, van der Mey AGL, van Linge A, van Benthem PPG, Hensen EF, Stiggelbout AM Abstract PURPOSE: In cases of small- to medium-sized vestibular schwannomas, three management strategies can be opted for: active surveillance, surgery or radiotherapy. In these cases,...
Thu Oct 08, 2020 14:34
ACE2 expression in allergic airway disease may decrease the risk and severity of COVID-19. Eur Arch Otorhinolaryngol. 2020 Oct 06;: Authors: Chhapola Shukla S Abstract The coronavirus disease (COVID-19) is caused by Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and presents with respiratory symptoms which can be life threatening in severe cases. At the start of the pandemic, allergy, asthma, and chronic obstructive pulmonary...
Thu Oct 08, 2020 14:34
Non-idiopathic peripheral facial palsy: prognostic factors for outcome. Eur Arch Otorhinolaryngol. 2020 Oct 06;: Authors: Geißler K, Urban E, Volk GF, Klingner CM, Witte OW, Guntinas-Lichius O Abstract OBJECTIVES: There is a lack of data on patients' and diagnostic factors for prognostication of complete recovery in patients with non-idiopathic peripheral facial palsy (FP). METHODS: Cohort register-based study of 264 patients with...
Thu Oct 08, 2020 14:34
Conservative Management of Juxtapleural Nodules at Low-Dose CT Lung Cancer Screening: Is This Prudent? Radiology. 2020 Oct 06;:203703 Authors: Godoy MCB PMID: 33026290 [PubMed - as supplied by publisher]
Thu Oct 08, 2020 14:33
Patient Triage for Resection of Metastatic Colorectal Cancer to the Liver: Can We Do Better Using MRI? Radiology. 2020 Oct 06;:203631 Authors: Bashir MR PMID: 33026289 [PubMed - as supplied by publisher]
Thu Oct 08, 2020 14:33
An Effective Method to Reduce the Interpretation Time in the Clinical Use of Digital Breast Tomosynthesis. Radiology. 2020 Oct 06;:203595 Authors: Chang JM PMID: 33026288 [PubMed - as supplied by publisher]
Thu Oct 08, 2020 14:33
Publication date: Available online 7 October 2020Source: CortexAuthor(s): Katharina S. Rufener, Astrid-Maria Husemann, Tino Zaehle
Thu Oct 08, 2020 14:28
Publication date: Available online 7 October 2020Source: CortexAuthor(s): Karla Matić, Hans Op de Beeck, Stefania Bracci
Thu Oct 08, 2020 14:28
Facial Nerve Meningioma: A Case Mimicking Facial Nerve Schwannoma. Ear Nose Throat J. 2020 Oct 06;:145561320962582 Authors: Gao W, Zi D, Lu L Abstract Facial nerve meningioma is exceedingly rare and tends to affect the geniculate ganglion. We present a case of facial nerve meningioma located in the internal auditory canal with a "labyrinthine tail," mimicking facial nerve schwannoma. The clinical and radiological features, growth patterns,...
Thu Oct 08, 2020 14:27
Primary First Bite Syndrome of the Parotid Gland: Case Report and Literature Review. Ear Nose Throat J. 2020 Oct 06;:145561320962584 Authors: Yang X, Yang X, Wang W, Zhang P, Hou R, Yang Y, Lei D, Wei J Abstract OBJECTIVE: A case of primary first bite syndrome (FBS), diagnosed in a patient with nonspecific adenocarcinoma of the deep lobe of the parotid gland. DATA SOURCES: A Medline literature search was conducted on PubMed,...
Thu Oct 08, 2020 14:27
Application of the Expanded Neck Flap for Face and Ear Reconstruction in Burn Patients: A Report on 2 Cases. Ear Nose Throat J. 2020 Oct 06;:145561320963592 Authors: Guo P, Pan B, He L, Jiang H, Yang Q, Lin L Abstract Reconstruction of auricular deformities and facial scars after burns is a challenging undertaking for surgeons. Excessive scar tissue, a poor blood supply and the paucity of available skin are all substantial difficulties...
Thu Oct 08, 2020 14:27
Multiparametric Analysis of Factors Associated With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps. Ear Nose Throat J. 2020 Oct 06;:145561320960357 Authors: Fadda GL, Galizia A, Galizia G, Castelnuovo P, Bignami M, Cavallo G Abstract INTRODUCTION: Previous studies have reported a diverse range of threshold values for blood eosinophilia. In addition, a single predictive biomarker for eosinophilic chronic rhinosinusitis (CRS) with...
Thu Oct 08, 2020 14:27
Alternative therapies for chronic rhinosinusitis: A review. Ear Nose Throat J. 2020 Oct 06;:145561320939415 Authors: Griffin AS, Cabot P, Wallwork B, Panizza B Abstract The use of alternative medicine in chronic rhinosinus-itis (CRS) continues to increase in popularity, for the most part without meeting the burden of being based on sound clinical evidence. New and emerging treat-ments, both natural and developed, are numerous, and it remains...
Thu Oct 08, 2020 14:27
The activation of procarcinogens by CYP1A1/1B1 and related chemopreventive agents: A review. Curr Cancer Drug Targets. 2020 Oct 06;: Authors: Li Y, Cui J, Jia J Abstract CYP1A1 and CYP1B1 are extrahepatic P450 family members involved in the metabolism of procarcinogens, such as PAHs, heterocyclic amines and halogen-containing organic compounds. CYP1A1/1B1 also participate in the metabolism of endogenous 17-β-estradiol, producing estradiol hydroquinones...
Thu Oct 08, 2020 14:27
Experience, Perceptions, and Recommendations Concerning COVID-19-Related Clinical Research Adjustments. J Natl Compr Canc Netw. 2020 Oct 07;:1-8 Authors: Gerber DE, Sheffield TY, Beg MS, Williams EL, Clark VL, Xie Y, Holbein MEB, Skinner CS, Lee SJC Abstract BACKGROUND: During the COVID-19 public health emergency, the FDA and NIH altered clinical trial requirements to protect participants and manage study conduct. Given their detailed knowledge...
Thu Oct 08, 2020 14:20
Nocturnal peripheral vasoconstriction predicts the frequency of severe acute pain episodes in children with sickle cell disease. Am J Hematol. 2020 Oct 07;: Authors: Chalacheva P, Ji Y, Rosen CL, DeBaun MR, Khoo MCK, Coates TD Abstract The basic model of SCD physiology states that vaso-occlusion occurs when hemoglobin S-containing red blood cells (RBC) undergo sickling before they escape the capillary into a larger vessel. We have shown that...
Thu Oct 08, 2020 14:20
Is chemotherapy alone an option as initial treatment for low-grade oligodendrogliomas? Curr Opin Neurol. 2020 Oct 06;: Authors: Rudà R, Touat M, Soffietti R Abstract PURPOSE OF REVIEW: The management of low-grade (grade II) oligodendrogliomas is still controversial, due to their rarity and long-term survival. According to recent WHO 2016 Classification of central nervous system tumors oligodendrogliomas are defined by the coexistence of molecular...
Thu Oct 08, 2020 14:20
Analysis of the Implementation of Telehealth Visits for Care of Patients With Cancer in Houston During the COVID-19 Pandemic. JCO Oncol Pract. 2020 Oct 07;:OP2000572 Authors: Darcourt JG, Aparicio K, Dorsey PM, Ensor JE, Zsigmond EM, Wong ST, Ezeana CF, Puppala M, Heyne KE, Geyer CE, Phillips RA, Schwartz RL, Chang JC Abstract PURPOSE: The purpose of this study was to evaluate the use of telemedicine amid the SARS-CoV-2 pandemic in patients...
Thu Oct 08, 2020 14:20
IAEA contribution to the development of copper-64 radiopharmaceuticals for theranostic applications.
IAEA contribution to the development of copper-64 radiopharmaceuticals for theranostic applications. Q J Nucl Med Mol Imaging. 2020 Oct 07;: Authors: Jalilian AR, Osso JA, Vera-Araujo J, Kumar V, Harris MJ, Gutfilen B, Guérin B, Li H, Zhuravlev F, Chakravarty R, Alirezapour B, Ávila-Rodríguez MA, Khan IU, Aljammaz I, Assaad T, Luurtsema G, Smith J, Duatti A Abstract Copper-64 is a very attractive radioisotope with unique nuclear properties...
Thu Oct 08, 2020 14:20
Identification of prognostic factors in childhood T-cell acute lymphoblastic leukemia: Results from DFCI ALL Consortium Protocols 05-001 and 11-001. Pediatr Blood Cancer. 2020 Oct 07;:e28719 Authors: Burns MA, Place AE, Stevenson KE, Gutiérrez A, Forrest S, Pikman Y, Vrooman LM, Harris MH, Hunt SK, O'Brien JE, Asselin BL, Athale UH, Clavell LA, Cole PD, Gennarini LM, Kahn JM, Kelly KM, Laverdiere C, Leclerc JM, Michon B, Schorin MA, Sulis ML, Welch JJG, Neuberg...
Thu Oct 08, 2020 14:20
Attendance for diagnostic colposcopy among high-risk human papillomavirus positive women in a Brazilian feasibility study. Int J Gynaecol Obstet. 2020 Oct 07;: Authors: Buss LF, Levi JE, Longatto-Filho A, Cohen DD, Cury L, Martins TR, Fuza LM, Villa LL, Eluf-Neto J Abstract OBJECTIVE: To investigate factors associated with colposcopy attendance in HPV-positive women in São Paulo, Brazil. METHODS: We analyzed data from a prospective...
Thu Oct 08, 2020 14:20
Human spermbots for patient-representative 3D ovarian cancer cell treatment. Nanoscale. 2020 Oct 07;: Authors: Xu H, Medina-Sánchez M, Zhang W, Seaton MPH, Brison DR, Edmondson RJ, Taylor SS, Nelson L, Zeng K, Bagley S, Ribeiro C, Restrepo LP, Lucena E, Schmidt CK, Schmidt OG Abstract Cellular micromotors are attractive for locally delivering high concentrations of drug, and targeting hard-to-reach disease sites such as cervical cancer and...
Thu Oct 08, 2020 14:20
Zanubrutinib: a new BTK inhibitor for treatment of relapsed/refractory mantle cell lymphoma. Drugs Today (Barc). 2020 Aug;56(8):531-539 Authors: Weaver AN, Jimeno A Abstract Mantle cell lymphoma (MCL) has historically been an aggressive disease with poor long-term survival. In the last decade, Bruton tyrosine kinase (BTK) inhibition has emerged as a new treatment strategy for MCL, especially in the relapsed/refractory (r/r) setting. Zanubrutinib,...
Thu Oct 08, 2020 14:20
A dynamic portrait of adverse events for breast cancer patients: results from a phase II clinical trial of eribulin in advanced HER2-negative breast cancer. Breast Cancer Res Treat. 2020 Oct 06;: Authors: Filho OM, Giobbie-Hurder A, Lin NU, Faggen M, Come S, Openshaw T, Constantine M, Walsh J, Freedman RA, Schneider B, Burstein HJ, Mayer EL Abstract PURPOSE: Adverse events (AE) during oncology clinical trials are typically reported using the...
Thu Oct 08, 2020 14:20
Dosimetric analysis of the effects of a temporary tissue expander on the radiotherapy technique. Radiol Med. 2020 Oct 06;: Authors: Park SH, Kim YS, Choi J Abstract AIMS: The current study aimed to evaluate the dose effect of a temporary tissue expander (TTE) according to the radiotherapy technique for breast cancer patients. MATERIALS AND METHODS: Computed tomography images of a 3D-printed breast phantom with a TTE were acquired for...
Thu Oct 08, 2020 14:20
Insulinoma-associated protein 1 (INSM1) expression in breast carcinomas with neuroendocrine morphologies: application and future prospective. Virchows Arch. 2020 Oct 06;: Authors: Kawasaki T, Kaira K Abstract Herein, we describe the first cases of neuroendocrine (NE) phenotype mammary carcinomas in which the NE nature of the tumors was confirmed only by insulinoma-associated protein 1 (INSM1), without expressions of traditional "gold standard"...
Thu Oct 08, 2020 14:20
Inhibition of Autophagy Amplifies Baicalein-Induced Apoptosis in Human Colorectal Cancer. Mol Ther Oncolytics. 2020 Dec 16;19:1-7 Authors: Phan T, Nguyen VH, A'lincourt Salazar M, Wong P, Diamond DJ, Yim JH, Melstrom LG Abstract Baicalein is a Chinese herbal compound extracted from Scutellaria baicalensis that has anti-tumor properties. The aim of this study was to elucidate the mechanisms of action of baicalein against human colorectal cancer...
Thu Oct 08, 2020 14:20
Considerations for future novel human-infecting coronavirus outbreaks. Surg Neurol Int. 2020;11:260 Authors: Sinclair G, Johnstone P, Hatiboglu MA Abstract Up until, June 13, 2020, >7,500,000 cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and >400,000 deaths, across 216 countries, have been confirmed by the World Health Organization (WHO). With reference to the two previous beta-CoV outbreaks (SARS-CoV and middle...
Thu Oct 08, 2020 14:20
Impact of palliative therapies in metastatic esophageal cancer patients not receiving chemotherapy. World J Gastrointest Surg. 2020 Sep 27;12(9):377-389 Authors: Kim S, DiPeri TP, Guan M, Placencio-Hickok VR, Kim H, Liu JY, Hendifar A, Klempner SJ, Nipp R, Gangi A, Burch M, Waters K, Cho M, Chao J, Atkins K, Kamrava M, Tuli R, Gong J Abstract BACKGROUND: Palliative therapy has been associated with improved overall survival (OS) in several tumor...
Thu Oct 08, 2020 14:20
FBXO11 is a candidate tumor suppressor in the leukemic transformation of myelodysplastic syndrome. Blood Cancer J. 2020 Oct 06;10(10):98 Authors: Schieber M, Marinaccio C, Bolanos LC, Haffey WD, Greis KD, Starczynowski DT, Crispino JD Abstract Myelodysplastic syndrome (MDS) is a heterogeneous myeloid malignancy characterized by blood cell morphological dysplasia, ineffective clonal hematopoiesis, and risk of transformation to secondary acute...
Thu Oct 08, 2020 14:20
Survival after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastases: A systematic review and discussion of latest controversies. Surgeon. 2020 Oct 03;: Authors: Flood M, Narasimhan V, Waters P, Ramsay R, Michael M, Warrier S, Heriot A Abstract INTRODUCTION: Peritoneal metastases confer the worst survival amongst all sites of metastatic colorectal cancer. The adoption of cytoreductive surgery...
Thu Oct 08, 2020 14:20
Usefulness of 18F-FDOPA PET for the management of primary brain tumors: a systematic review of the literature. Cancer Imaging. 2020 Oct 06;20(1):70 Authors: Somme F, Bender L, Namer IJ, Noël G, Bund C Abstract Contrast-enhanced magnetic resonance imaging is currently the standard of care in the management of primary brain tumors, although certain limitations remain. Metabolic imaging has proven useful for an increasing number of indications...
Thu Oct 08, 2020 14:20
A phase II study of daily carboplatin plus irradiation followed by durvalumab for stage III non-small cell lung cancer patients with PS 2 up to 74 years old and patients with PS 0 or 1 from 75 years: NEJ039A (trial in progress). BMC Cancer. 2020 Oct 06;20(1):961 Authors: Kaira K, Mouri A, Kato S, Yoshimura K, Kagamu H, Kobayashi K Abstract BACKGROUND: Durvalumab is a standard drug used during maintenance therapy after chemoradiotherapy in patients...
Thu Oct 08, 2020 14:20
Identification of transcobalamin deficiency with two novel mutations in the TCN2 gene in a Chinese girl with abnormal immunity: a case report. BMC Pediatr. 2020 Oct 06;20(1):460 Authors: Zhan S, Cheng F, He H, Hu S, Feng X Abstract BACKGROUND: Transcobalamin (TC) transports vitamin B12 from blood into cells. TC II deficiency is a rare autosomal recessive disorder. It is characterized by failure to thrive, diarrhoea, pallor, anaemia, pancytopenia...
Thu Oct 08, 2020 14:20
Using the No-Apnea score to screen for obstructive sleep apnea in adults referred to a sleep laboratory: comparative study of the performance of the instrument by gender. J Bras Pneumol. 2020;46(5):e20190297 Authors: Duarte RLM, Silveira FJMD, Sá TSOE, Rabahi MF, Mello FCQ, Gozal D Abstract OBJECTIVE: To evaluate the performance of the No-Apnea score, a simplified screening instrument for obstructive sleep apnea (OSA), by gender. METHODS:...
Thu Oct 08, 2020 14:19
STOP-Bang and NoSAS questionnaires as a screening tool for OSA: which one is the best choice? Rev Assoc Med Bras (1992). 2020 Sep;66(9):1203-1209 Authors: Costa JC, Rebelo-Marques A, Machado JPN, Valentim BMF, Ferreira CSAV, Gonçalves JDO, Gama JMDR, Teixeira MFL, Moita JJM Abstract INTRODUCTION: Currently there has been significant growth in the number of patients with suspected obstructive sleep apnea (OSA) referred to sleep clinics. In this...
Thu Oct 08, 2020 14:19
[Obstructive sleep apnea syndrome : CPAP or Mandibular Advancement Device?] Rev Med Suisse. 2020 Oct 07;16(709):1865-1869 Authors: Teiga P, Chatelain S, Heinzer R, Lambercy K Abstract Obstructive sleep apnea syndrome (OSAS) is a respiratory disorder affecting up to 49 % and 23 % of middle to older aged men and women respectively. CPAP (continuous positive airway pressure) is the gold-standard treatment for severe apneas. In mild and moderate...
Thu Oct 08, 2020 14:19
Opioid Prescribing Patterns Following Pediatric Tonsillectomy in the United States, 2009-2017. Laryngoscope. 2020 Oct 07;: Authors: Qian ZJ, Alyono JC, Jin MC, Cooperman SP, Cheng AG, Balakrishnan K Abstract OBJECTIVES: Assess national trends in opioid prescription following pediatric tonsillectomy: 1) overall percentage receiving opioids and mean quantity, 2) changes during 2009-2017, and 3) determinants of prescription patterns. ...
Thu Oct 08, 2020 14:19
Outcomes of Adenotonsillectomy for Obstructive Sleep Apnea in Prader-Willi Syndrome: Systematic Review and Meta-analysis. Laryngoscope. 2020 Jul 27;: Authors: Clements AC, Dai X, Walsh JM, Sterni LM, Prichett L, Boss EF, Seal SM, Ryan MA Abstract OBJECTIVES: Prader-Willi syndrome (PWS) increases the risk of obstructive sleep apnea (OSA) due to obesity, hypotonia, and abnormal ventilatory responses. We evaluated post-adenotonsillectomy complications,...
Thu Oct 08, 2020 14:19
Evaluation of the Oropharyngeal Airway Space in Class II Malocclusion Treated with Mandibular Activator: A Retrospective Study. J Contemp Dent Pract. 2020 Jun 01;21(6):666-672 Authors: Cortese M, Pigato G, Casiraghi G, Ferrari M, Bianco E, Maddalone M Abstract AIM: The development of a class II malocclusion is usually related to a reduced oropharyngeal airway space. In order to prevent airway obstruction, functional appliances are commonly...
Thu Oct 08, 2020 14:19
Impact of obstructive sleep apnea-related symptoms on surgical wound complications in breast cancer patients: pilot study in a tertiary health center in Turkey. Sleep Breath. 2020 Oct 06;: Authors: Ozdilekcan C, Kutun S, Dogan L Abstract PURPOSE: Wound healing is an important factor influencing morbidity following surgical procedures. The association of obstructive sleep apnea (OSA) with numerous postoperative complications has been previously...
Thu Oct 08, 2020 14:19
Sleep-disordered breathing in adult patients with mitochondrial diseases: A cohort study. Neurology. 2020 Oct 06;: Authors: Primiano G, Brunetti V, Vollono C, Losurdo A, Moroni R, Della Marca G, Servidei S Abstract OBJECTIVE: To describe the prevalence and characteristics of sleep-disordered breathing (SDB) in a large cohort of patients with genetically confirmed mitochondrial diseases. METHODS: This is a prospective observational...
Thu Oct 08, 2020 14:19
Sleep and Sex: A Review of the Interrelationship of Sleep and Sexuality Disorders in the Female Population, Through the Lens of Sleeping Beauty Syndrome. Sex Med Rev. 2020 Oct 03;: Authors: Zwerling B, Keymeulen S, Krychman ML Abstract INTRODUCTION: For many, sleep and sex are crucial for physical, emotional, and mental well-being. Poor sleep quality is linked to a myriad of ailments from coronary artery disease to major depressive disorder....
Thu Oct 08, 2020 14:19
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