Facial Nerve Meningioma: A Case Mimicking Facial Nerve Schwannoma. Ear Nose Throat J. 2020 Oct 06;:145561320962582 Authors: Gao W, Zi D, Lu L Abstract Facial nerve meningioma is exceedingly rare and tends to affect the geniculate ganglion. We present a case of facial nerve meningioma located in the internal auditory canal with a "labyrinthine tail," mimicking facial nerve schwannoma. The clinical and radiological features, growth patterns,...
Thu Oct 08, 2020 13:28
Primary First Bite Syndrome of the Parotid Gland: Case Report and Literature Review. Ear Nose Throat J. 2020 Oct 06;:145561320962584 Authors: Yang X, Yang X, Wang W, Zhang P, Hou R, Yang Y, Lei D, Wei J Abstract OBJECTIVE: A case of primary first bite syndrome (FBS), diagnosed in a patient with nonspecific adenocarcinoma of the deep lobe of the parotid gland. DATA SOURCES: A Medline literature search was conducted on PubMed,...
Thu Oct 08, 2020 13:28
Alternative therapies for chronic rhinosinusitis: A review. Ear Nose Throat J. 2020 Oct 06;:145561320939415 Authors: Griffin AS, Cabot P, Wallwork B, Panizza B Abstract The use of alternative medicine in chronic rhinosinus-itis (CRS) continues to increase in popularity, for the most part without meeting the burden of being based on sound clinical evidence. New and emerging treat-ments, both natural and developed, are numerous, and it remains...
Thu Oct 08, 2020 13:28
TriPla Regimen: A new treatment approach for patients with neovascular age-related macular degeneration in the COVID-19 "era". Eur J Ophthalmol. 2020 Oct 07;:1120672120963448 Authors: Sacconi R, Borrelli E, Vella G, Querques L, Prascina F, Zucchiatti I, Bandello F, Querques G Abstract In the last months, a rapidly increasing number of people have been infected with severe acute respiratory syndrome coronavirus 2, the virus causing coronavirus...
Thu Oct 08, 2020 13:28
Immunomodulative Effects of Chamaecyparis obtusa Essential Oil in Mouse Model of Allergic Rhinitis. Molecules. 2020 Oct 02;25(19): Authors: Shin SH, Ye MK, Lee DW, Che MH Abstract The present study aims to investigate the immunomodulatory effects of essential oil from Chamaecyparis obtusa (EOCO) in an ovalbumin (OVA)-induced allergic rhinitis (AR) mouse model. BALB/c mice were intraperitoneally sensitized and stimulated with OVA. From...
Thu Oct 08, 2020 13:28
Related Articles Functional recurrent laryngeal nerve regeneration using a silicon tube containing a collagen gel in a rat model. PLoS One. 2020;15(8):e0237231 Authors: Asai R, Ishii S, Mikoshiba I, Kazama T, Matsuzaki H, Oshima T, Matsumoto T Abstract In this study, we examined the effect of differing gap lengths on regeneration of transected recurrent laryngeal nerves using silicon tubes containing type I collagen gel and the ability of...
Thu Oct 08, 2020 13:28
Related Articles Self-reported anosmia and dysgeusia as key symptoms of coronavirus disease 2019. CJEM. 2020 09;22(5):595-602 Authors: Lee DJ, Lockwood J, Das P, Wang R, Grinspun E, Lee JM Abstract OBJECTIVES: To slow down the transmission of coronavirus disease 2019 (COVID-19), it is important to identify specific symptoms for effective screening. While anosmia/hyposmia and dysgeusia/ageusia have been identified as highly prevalent symptoms,...
Thu Oct 08, 2020 13:28
Related Articles EMR quantity autopopulation removal on hospital discharge prescribing patterns: Implications for opioid stewardship. J Clin Pharm Ther. 2020 Feb;45(1):160-168 Authors: Villwock JA, Villwock MR, New J, Ator GA Abstract WHAT IS KNOWN AND OBJECTIVE: Prescription drug stewardship is critical. Autopopulation(AP) of medication quantities may influence prescriber behaviour. We investigate the impact of AP removal(APR) on opioid prescribing....
Thu Oct 08, 2020 13:28
Related Articles Not CD68 but stabilin-1 expression is associated with the risk of recurrence in patients with oral cavity squamous cell carcinoma. Head Neck. 2019 07;41(7):2058-2064 Authors: Kwon M, Yeo SC, Lee JS, Park JJ Abstract BACKGROUND: This study's aim was to identify CD68 and stabilin-1 expressions and their prognostic implications in patients with oral cavity cancer (OCC). METHODS: Stabilin-1 and CD68 immunochemical staining...
Thu Oct 08, 2020 13:28
Related Articles Detection of Epstein-Barr virus (EBV)-encoded microRNAs in plasma of patients with nasopharyngeal carcinoma. Head Neck. 2019 03;41(3):780-792 Authors: Gao W, Wong TS, Lv KX, Zhang MJ, Tsang RK, Chan JY Abstract BACKGROUND: Nasopharyngeal carcinoma (NPC) latently infected by Epstein-Barr virus (EBV) expresses 40 EBV BART microRNAs (miRNAs). Difference in diagnostic efficacy of these miRNAs on NPC detection was observed. Here,...
Thu Oct 08, 2020 13:28
Related Articles Promotion of skin wound healing using prevascularized oral mucosal cell sheet. Head Neck. 2019 03;41(3):774-779 Authors: Lee J, Shin D, Roh JL Abstract BACKGROUND: This study examined the potential use of our newly developed prevascularized oral mucosal cell sheet for the treatment of skin wounds. METHODS: Mucosal cell sheets containing cultured keratinocytes and plasma fibrin without (K sheet) or with a mixture of...
Thu Oct 08, 2020 13:28
Related Articles Prognostic significance of pretreatment 18F-fluorodeoxyglucose positron emission tomography evaluation using metabolic tumor volume of the primary tumor and lymph nodes in advanced hypopharyngeal cancer. Head Neck. 2019 03;41(3):739-747 Authors: Okazaki E, Kawabe J, Oishi M, Hosono M, Higashiyama S, Teranishi Y, Shiomi S, Iguchi H, Miki Y Abstract BACKGROUND: The purpose of this study was to retrospectively evaluate the usefulness...
Thu Oct 08, 2020 13:28
Related Articles Virtual evaluation of selected cervical lymph nodes with three-dimensional ultrasound in thyroid cancer patients after thyroidectomy. Head Neck. 2019 03;41(3):748-755 Authors: Frank SJ, Ahn SJ, Surks MI Abstract BACKGROUND: We evaluated the usefulness of three-dimensional (3D) ultrasound of cervical lymph nodes (LN), when two-dimensional (2D) ultrasound evaluation is not sufficient to clearly evaluate lymph node characteristics,...
Thu Oct 08, 2020 13:28
Related Articles Factors of local recurrence and organ preservation with transoral laser microsurgery in laryngeal carcinomas; CHAID decision-tree analysis. Head Neck. 2019 03;41(3):756-764 Authors: Vilaseca I, Nogués-Sabaté A, Avilés-Jurado FX, Berenguer J, Grau JJ, Verger E, Nadal A, Muxí A, Bernal-Sprekelsen M, Blanch JL Abstract BACKGROUND: Indications of transoral laser microsurgery (TLM) are conditioned by the risk of local relapse. ...
Thu Oct 08, 2020 13:28
Related Articles Socioeconomic disparities in a population of patients undergoing total thyroidectomy for benign disease. Head Neck. 2019 03;41(3):715-721 Authors: Wu TJ, Ha PK, El-Sayed IH, George JR, Heaton CM, Ryan WR, Russell MD Abstract BACKGROUND: This study examines the effect of insurance status (as a measure of socioeconomic status) on patient with benign thyroid disease. METHODS: A retrospective review was performed among...
Thu Oct 08, 2020 13:28
Related Articles Early experience of transoral thyroidectomy: Comparison of robotic and endoscopic procedures. Head Neck. 2019 03;41(3):730-738 Authors: Tae K, Lee DW, Song CM, Ji YB, Park JH, Kim DS, Tufano RP Abstract BACKGROUND: The aim of this study was to evaluate the feasibility, safety, and early surgical outcomes of transoral thyroidectomy and to compare robotic and endoscopic procedures. METHODS: A total of 37 patients underwent...
Thu Oct 08, 2020 13:28
Related Articles Utility of first positron emission tomography-computed tomography scan as a prognostic tool following treatment of sinonasal and skull base malignancies. Head Neck. 2019 03;41(3):701-706 Authors: Abu-Ghanem S, Yafit D, Ghanayem M, Abergel A, Yehuda M, Fliss DM Abstract BACKGROUND: The prognostic value of the first posttreatment whole body integrated positron emission tomography-computed tomography (PET/CT) scanning in patients...
Thu Oct 08, 2020 13:28
Abstract Soils play an important role in the ecosystem of karstic landscapes both as a buffer zone and as a source of acidity to belowground water. Although the microbiota of karstic soils is known to have a great effect on karstification processes, the activity and composition of these communities are largely unknown. This study gives a comparative analysis of soil microbial profiles from different parts of a doline located at Aggtelek, Hungary. The aim was to reveal the relationships...
Thu Oct 08, 2020 03:00
Abstract Objective To verify the validity of the prediction of oral intake recovery for inpatients with aspiration pneumonia using the Hyodo‐Komagane score. Background Patients admitted for treatment of aspiration pneumonia sometimes have difficulty in resuming oral intake due to decreased swallowing function. Predicting whether the swallowing function will recover enough to achieve oral ingestion at discharge is an important factor in developing a treatment strategy. No studies have investigated...
Tue Oct 06, 2020 18:57
Internuclear Ophthalmoplegia as the First Manifestation of Pediatric-Onset Multiple Sclerosis and Concurrent Lyme Disease. Am J Case Rep. 2020 Oct 07;21:e925220 Authors: Chao J, Saleem S, Tausif HN, Levasseur K, Stec LA Abstract BACKGROUND Internuclear ophthalmoplegia (INO) presents as a disruption of horizontal conjugate ocular movement and is an uncommon finding in the pediatric population. Its presence warrants a thorough evaluation to search...
Thu Oct 08, 2020 13:18
Hemorrhagic Bullous Lichen Sclerosus: A Case Report. Am J Case Rep. 2020 Oct 07;21:e919353 Authors: Khatib J, Wargo JJ, Krishnamurthy S, Travers JB Abstract BACKGROUND Lichen sclerosus (LS) is a chronic autoimmune dermatosis characterized by white, sclerotic, atrophic plaques. Classic LS commonly occurs in the anogenital region, while extragenital lichen sclerosis typically occurs on the trunk and proximal extremities. Bullous lichen sclerosus...
Thu Oct 08, 2020 13:18
Adjuvant Trastuzumab Emtansine (T-DM1) and Concurrent Radiotherapy for Residual Invasive HER2-positive Breast Cancer: Single-center Preliminary Results. Am J Clin Oncol. 2020 Oct 06;: Authors: Zolcsák Z, Loirat D, Fourquet A, Kirova YM Abstract OBJECTIVES: The treatment of nonmetastatic HER2-positive breast cancer with residual invasive disease using concurrent Trastuzumab emtansine (T-DM1) and radiotherapy appears to be an effective option....
Thu Oct 08, 2020 13:08
A Novel Proteomic Method Reveals NLS Tagging of T-DM1 Contravenes Classical Nuclear Transport in a Model of HER2-Positive Breast Cancer. Mol Ther Methods Clin Dev. 2020 Dec 11;19:99-119 Authors: Lacasse V, Beaudoin S, Jean S, Leyton JV Abstract The next breakthrough for protein therapeutics is effective intracellular delivery and accumulation within target cells. Nuclear localization signal (NLS)-tagged therapeutics have been hindered by the...
Thu Oct 08, 2020 13:08
Prediction of oral intake recovery for inpatients with aspiration pneumonia by videoendoscopic evaluation using the Hyodo-Komagane score in Japan. J Oral Rehabil. 2020 Oct 06;: Authors: Kimura M, Nakayama E, Ogawa Y, Sato M, Inagawa M, Watanabe M, Sato M, Naganuma A, Ogawa T, Ueda K Abstract OBJECTIVE: To verify the validity of the prediction of oral intake recovery for inpatients with aspiration pneumonia using the Hyodo-Komagane score. ...
Thu Oct 08, 2020 13:07
Enhanced Otolith Function Despite Severe Labyrinthine Damage in a Case of Pneumolabyrinth and Pneumocephalus Due to Otogenic Meningitis Associated With Superior Canal Dehiscence. Otol Neurotol. 2020 Sep 22;: Authors: Castellucci A, Botti C, Renna L, Delmonte S, Moratti C, Pascarella R, Bianchin G, Ghidini A Abstract OBJECTIVE: To describe a rare case of pneumolabyrinth (PNL) and pneumocephalus (PNC) due to otogenic meningitis in a patient...
Thu Oct 08, 2020 13:06
Patients with vertigo/dizziness of unknown origin during follow-ups by general otolaryngologists at outpatient town clinic. Auris Nasus Larynx. 2020 Oct 03;: Authors: Nishikawa D, Wada Y, Shiozaki T, Shugyo M, Ito T, Ota I, Kitahara T Abstract OBJECTIVES: The purpose of this study was to access the contribution of vertigo/dizziness-related patients' interview and examinations during short-term hospitalization in determining the accurate...
Thu Oct 08, 2020 13:06
Debating intoxication: Response to commentaries. Addiction. 2020 Oct 06;: Authors: Crombag HS, Child JJ, Sullivan GR PMID: 33025704 [PubMed - as supplied by publisher]
Thu Oct 08, 2020 13:01
An amendment to this paper has been published and can be accessed via the original article.
Wed Oct 07, 2020 03:00
Leaves have highly diverse morphologies. However, with an evolutionary history of approximately 200 million years, leaves of the pine family are relatively monotonous and often collectively called “needles”, a...
Wed Oct 07, 2020 03:00
Parkinson’s disease (PD) is the second most common neurodegenerative disorder. PD associated human UCHL1 (Ubiquitin C-terminal hydrolase L1) gene belongs to the family of deubiquitinases and is known to be highly...
Wed Oct 07, 2020 03:00
Abstract Objectives To perform a systematic review of the literature, investigating the influence of tooth mineral tissues genes on dental caries. Materials and methods Five databases were searched. Only human studies with cross-sectional, longitudinal, and case-control design were included. Meta-analysis was performed for each polymorphism,...
Thu Oct 08, 2020 12:20
Abstract Objectives The purpose of this cross-sectional study was to investigate whether polymorphisms in vitamin D receptor (VDR) genes increase the prevalence of dental caries, molar incisor hypomineralization (MIH), and hypomineralized primary second molars (HPSM). Material and methods A representative population-based sample of 731 schoolchildren,...
Thu Oct 08, 2020 12:20
Abstract Objective To evaluate the effectiveness of microwave disinfection in treating Candida-associated denture stomatitis (CADS). Materials and methods The PubMed/MEDLINE, Embase, and Scopus databases were searched for reports on randomized clinical trials (RCTs) published in English until May 2020 (PROSPERO CRD42020192062) that evaluated...
Thu Oct 08, 2020 12:20
Abstract Objectives Pain management for the extraction of the mandibular third molar is a challenge as compelling evidence in comparative anaesthetics is currently lacking. Materials and methods Thorough literature searches took place in PubMed, ScienceDirect, CENTRAL, Embase, Web of Science, CBM, and CNKI. Thirty-three trials were meta-analysed...
Thu Oct 08, 2020 12:20
Abstract Objectives To date, the relationship between cardiovascular disease (CVD) and endodontic treatment outcomes remains elusive with mixed reports. Thus, the purpose of this systematic review of longitudinal cohort studies was to evaluate whether CVD was a risk factor for endodontic outcome. Materials and methods Two reviewers independently...
Thu Oct 08, 2020 12:20
Abstract Objectives The aim of the study was to investigate the impact of two hyaluronan (HA) formulations on the osteogenic potential of osteoblast precursors. Materials and methods Proliferation rates of HA-treated mesenchymal stromal ST2 and pre-osteoblastic MC3T3-E1 cells were determined by 5-bromo-20-deoxyuridine (BrdU) assay. Expression...
Thu Oct 08, 2020 12:20
Abstract Objective The aim of this investigation was to compare clinical performance and in vitro wear of temporary CAD/CAM and cartridge crowns. This study is an approach to estimate the influence of in vivo use and laboratory simulation on temporary crowns. Materials and methods A total of 90 crowns were fabricated from each temporary CAD/CAM...
Thu Oct 08, 2020 12:20
Abstract Objectives This systematic review assessed the clinical question: ‘Does ultrasonography (USG)-guided arthrocentesis provide better outcomes than conventional arthrocentesis in patients with temporomandibular disorder (TMD)?’ Materials and methods The review was conducted based on the Preferred Reporting Items for Systematic Reviews...
Thu Oct 08, 2020 12:20
Cover of this issue. Hematoxylin and eosin image of the pattern of microvessels in adenocarcinoma of the lung. See also Changchien et al. (pp. https://doi.org/10.1111/cas.145843747–3758 of this issue).
Wed Oct 07, 2020 21:31
Abstract Reliable biomarkers for upper tract urothelial carcinoma (UTUC) have yet to be found. Plasma cell‐free DNA (cfDNA) has been clinically applied as a minimally invasive blood biomarker for various types of cancer. We investigated the utility of plasma cfDNA as a blood biomarker in UTUC patients. The fragment size of plasma cfDNA was shorter and the concentration of plasma cfDNA was higher in UTUC patients than in healthy controls. The fragment size of plasma cfDNA had a moderate accuracy...
Wed Oct 07, 2020 13:14
Clinical significance of tumor‐associated immune cells in patients with oral squamous cell carcinoma
Abstract Background The expression of PD‐L1 in tumor cells and infiltration of tumor‐associated immune cells (TAICs) might reflect the tumor biology of head and neck cancer. We aimed to characterize their prognostic roles in oral squamous cell carcinomas (OSCCs). Methods We enrolled 103 OSCC patients who underwent definitive surgery. Immune expression levels of PD‐L1, PD‐1, CD3, CD4, CD8, and CD68 were assessed in surgically resected specimens. We evaluated the effects of immune marker...
Wed Oct 07, 2020 20:42
Abstract Background Human papillomavirus (HPV)‐positive oropharyngeal squamous cell carcinoma (OPSCC) have better prognosis and treatment response compared to HPV‐negative OPSCC. This study aims to noninvasively predict HPV status of OPSCC using clinical and/or radiological variables. Methods Seventy‐seven magnetic resonance radiomic features were extracted from T1‐weighted postcontrast images of the primary tumor of 153 patients. Logistic regression models were created to predict HPV status,...
Wed Oct 07, 2020 20:42
Abstract Background In remote thyroid surgery, a reliable intraoperative neuromonitoring (IONM) procedure is an important tool for reducing injury to recurrent laryngeal nerve (RLN). This study proposes an alternative or adjunct technique for performing full percutaneous (PC) IONM and confirms its feasibility in animal experiments. Methods This prospective porcine model study enrolled four piglets with eight nerve sides. Evoked electromyography (EMG) was stimulated from PC ball‐tip probe,...
Wed Oct 07, 2020 16:16
With PCR becoming one of the most important and widely-used diagnostic tools for infectious diseases of poultry, an urgent need has developed for an endogenous internal control (EIC) that monitors the quality ...
Wed Oct 07, 2020 03:00
Journal of International Medical Research, Volume 48, Issue 10, October 2020. Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is a novel clinical disease that is characterized by elevated serum IgG4 concentrations and tumefaction or tissue infiltrated by IgG4+ plasma cells. The clinical manifestations of IgG4-RD depend on the type of tissues affected. IgG4-related sclerosing cholangitis is a type of IgG4-RD. We report a patient who initially visited a local hospital with a 5-month history of jaundice....
Wed Oct 07, 2020 13:58
Journal of International Medical Research, Volume 48, Issue 10, October 2020. ObjectiveThe increasing number of spinal surgeries being performed in the elderly has increased the incidence of postoperative delirium. The prediction of delirium is complex, and few studies have been performed to examine the preoperative risk factors for delirium after spinal surgery in the elderly. This study was performed to clarify such risk factors in patients aged ≥75 years undergoing spinal surgery.MethodThis retrospective...
Wed Oct 07, 2020 05:49
Journal of International Medical Research, Volume 48, Issue 10, October 2020. ObjectivePolymorphisms in the tumor necrosis factor superfamily 15 (TNFSF15) gene contribute to susceptibility to inflammatory bowel disease (IBD). However, associations between TNFSF15 rs6478109, rs7869487, and rs7865494 polymorphisms and IBD remain unclear.MethodsEligible articles were retrieved from the PubMed, EMBASE, Web of Science, and CNKI databases through 20 March 2020. Pooled odds ratios (ORs) with 95% confidence...
Wed Oct 07, 2020 05:48
Journal of International Medical Research, Volume 48, Issue 10, October 2020. ObjectiveRecessive X-linked ichthyosis (RXLI) caused by deficiency of the steroid sulfatase gene (STS) has a reported prevalence of 1/2000 to 1/6000. The present study aimed to characterize the phenotypes and genotypes of two Chinese families with RXLI.MethodsThe patients were referred to the Family Planning Research Institute of Hunan Province for genetic counseling. Their skin phenotypes were photographed, and venous...
Wed Oct 07, 2020 05:47
Journal of International Medical Research, Volume 48, Issue 10, October 2020. Renal cell carcinoma (RCC) associated with Xp11.2 translocation/transcription factor E3 (TFE3) gene fusion is a rare and independent subtype of RCC included in the classification of MiT (microphthalmia-associated transcriptional factor) family translocation RCC. Herein, we report an adult case of Xp11.2 translocation RCC, and review the relevant literature to improve our understanding of the pathogenesis, epidemiology,...
Wed Oct 07, 2020 05:44
New England Journal of Medicine, Ahead of Print.
Wed Oct 07, 2020 12:00
New England Journal of Medicine, Ahead of Print.
Wed Oct 07, 2020 12:00
New England Journal of Medicine, Ahead of Print.
Wed Oct 07, 2020 12:00
New England Journal of Medicine, Ahead of Print.
Wed Oct 07, 2020 12:00
New England Journal of Medicine, Ahead of Print.
Wed Oct 07, 2020 12:00
New England Journal of Medicine, Volume 383, Issue 15, Page 1469-1477, October 2020.
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New England Journal of Medicine, Volume 383, Issue 15, Page 1496-1498, October 2020.
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New England Journal of Medicine, Volume 383, Issue 15, Page 1494-1496, October 2020.
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New England Journal of Medicine, Volume 383, Issue 15, Page 1479-1480, October 2020.
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New England Journal of Medicine, Volume 383, Issue 15, Page 1458-1467, October 2020.
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New England Journal of Medicine, Volume 383, Issue 15, October 2020.
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New England Journal of Medicine, Volume 383, Issue 15, Page 1468-1468, October 2020.
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New England Journal of Medicine, Volume 383, Issue 15, Page 1489-1491, October 2020.
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New England Journal of Medicine, Volume 383, Issue 15, October 2020.
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New England Journal of Medicine, Volume 383, Issue 15, Page 1409-1411, October 2020.
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New England Journal of Medicine, Volume 383, Issue 15, Page 1401-1404, October 2020.
Wed Oct 07, 2020 11:55
New England Journal of Medicine, Ahead of Print.
Wed Oct 07, 2020 05:25
Transition from parent-delivered to self-management is a vulnerable time for adolescents and young adults (AYA) with allergy and asthma. There is currently no European guideline available for healthcare profes...
Wed Oct 07, 2020 03:00
Treatment adherence greatly influences the clinical outcomes in various fields of medicine, including management of asthma and COPD. With the recent implementation of a nationwide e-Health solutions in Poland,...
Wed Oct 07, 2020 03:00
Background In a recent trial, a 6‐session intervention (BMT‐CARE) integrating medical information with cognitive‐behavioral strategies improved quality of life (QOL), mood, coping skills, and self‐efficacy for family/friend caregivers of hematopoietic stem cell transplantation (HCT) recipients. This study examined whether improvements in coping and self‐efficacy mediated the intervention effects on QOL and mood. Methods From December 2017 to April 2019, 100 caregivers of HCT recipients were...
Wed Oct 07, 2020 16:08
Background Endoscopic sinus surgery (ESS) is used to treat chronic rhinosinusitis. However, nasal adhesions often develop postoperatively, triggered by chronic inflammation and local fibrosis. A poly L‐lactide (PLLA) electrospun microfibrous membrane is a functional biodegradable material that can be placed on the wound surface to protect the wound and prevent adhesions. Methods We divided 24 rabbits randomly into 2 groups, a control operation group (group A) and an operation+PLLA placement...
Wed Oct 07, 2020 19:11
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