Philos Trans R Soc Lond B Biol Sci. 2015 Aug 5;370(1674). pii: 20140252. doi: 10.1098/rstb.2014.0252.
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Butler JM1.
Author information
1
National Institute of Standards and Technology, Gaithersburg, MD, USA john.butler@nist.gov.
Abstract
The author's thoughts and opinions on where the field of forensic DNA testing is headed for the next decade are provided in the context of where the field has come over the past 30 years. Similar to the Olympic motto of 'faster, higher, stronger', forensic DNA protocols can be expected to become more rapid and sensitive and provide stronger investigative potential. New short tandem repeat (STR) loci have expanded the core set of genetic markers used for human identification in Europe and the USA. Rapid DNA testing is on the verge of enabling new applications. Next-generation sequencing has the potential to provide greater depth of coverage for information on STR alleles. Familial DNA searching has expanded capabilities of DNA databases in parts of the world where it is allowed. Challenges and opportunities that will impact the future of forensic DNA are explored including the need for education and training to improve interpretation of complex DNA profiles.
© 2015 The Author(s) Published by the Royal Society. All rights reserved.
KEYWORDS:
DNA; DNA databases; forensic science; short tandem repeat
PMID: 26101278 PMCID: PMC4580997 DOI: 10.1098/rstb.2014.0252
.
Butler JM1.
Author information
1
National Institute of Standards and Technology, Gaithersburg, MD, USA john.butler@nist.gov.
Abstract
The author's thoughts and opinions on where the field of forensic DNA testing is headed for the next decade are provided in the context of where the field has come over the past 30 years. Similar to the Olympic motto of 'faster, higher, stronger', forensic DNA protocols can be expected to become more rapid and sensitive and provide stronger investigative potential. New short tandem repeat (STR) loci have expanded the core set of genetic markers used for human identification in Europe and the USA. Rapid DNA testing is on the verge of enabling new applications. Next-generation sequencing has the potential to provide greater depth of coverage for information on STR alleles. Familial DNA searching has expanded capabilities of DNA databases in parts of the world where it is allowed. Challenges and opportunities that will impact the future of forensic DNA are explored including the need for education and training to improve interpretation of complex DNA profiles.
© 2015 The Author(s) Published by the Royal Society. All rights reserved.
KEYWORDS:
DNA; DNA databases; forensic science; short tandem repeat
PMID: 26101278 PMCID: PMC4580997 DOI: 10.1098/rstb.2014.0252
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