Multiomics STEP up in correlative analysis of response to CAR T cells

AlexandrosSfakianakis shared this article with you from Inoreader Multiomics STEP up in correlative analysis of response to CAR T cells via Nat R Clinical Oncology Nature Reviews Clinical Oncology, Published online: 15 February 2023; doi:10.1038/s41571-023-00742-5 Plasma cell-free DNA analysis has emerged as a powerful liquid biopsy assay to assess circulating tumour DNA in response to cancer treatments. A new study shows that cell-free DNA can also inform on expansion kinetics and tumour-infiltration patterns in patients receiving chimeric antigen receptor T cells and, together with circulating tumour DNA, provides vivid prognostic insights into intratumoural dynamics. View on Web

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