Exposure, Susceptibility, and Recovery: A Framework for Examining the Intersection of the Social and Physical Environment and Infectious Disease Risk

alexandrossfakianakis shared this article with you from Inoreader Exposure, Susceptibility, and Recovery: A Framework for Examining the Intersection of the Social and Physical Environment and Infectious Disease Risk via American Journal of Epidemiology - Advance Access Abstract Despite well-documented evidence that structurally disadvantaged populations are disproportionately affected by infectious diseases, our understanding of the pathways that connect structural disadvantage to the burden of infectious diseases is limited. We propose a conceptual framework to facilitate more rigorous examination and testing of hypothesized mechanisms through which social and environmental factors shape the burden of infectious diseases and lead to persistent inequities. Drawing upon the principles laid out by Link and Phelan in their landmark paper on social conditions, we offer an explication of potential pathways through which structural disadvantage (e.g., racism, sexism, and economic deprivation) operates to produce infectious disease inequities. Specifically, we describe how the social environment impacts an individual's risk of infectious disease through 1) increasing exposure to infectious pathogens; and 2) increasing suscep tibility to infection. This framework will facilitate both the systematic examination of the ways in which structural disadvantage shapes the burden of infectious disease and the design of interventions that can disrupt these pathways. View on Web

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