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Παρασκευή 2 Οκτωβρίου 2020

Gallbladder amyloidosis

Amyloid deposition is in fact fre- quent in the kidneys, the heart, the nervous system, the hepatosplenic and intestinal tract and can be present in bone marrow (40 ...
by D Tirotta - ‎2016 - ‎Cited by 7 - ‎Related articles
Feb 1, 2017 - Amyloidosis may be systemic or localised, and is caused by extracellular deposits of amorphous, insoluble fibrillar proteins. We present two ...
by V Lea - ‎2017
Sep 1, 2020 - Localization of amyloidosis in the gallbladder is uncommon; only eight cases have been reported. We describe a case of amyloidosis ...
... rare case of amyloid A (AA) deposition in the gallbladder and review the literature ... Thus, the definitive diagnosis was acute cholecystitis with AA amyloidosis.
Aug 30, 2014 - Histology proves after Congo red staining the diagnosis of Amyloidosis in the gallbladderAmyloidosis is a rare disease that exceptionally ...
Mar 30, 2007 - The final diagnosis, amyloidosis of the gallbladder, was obtained by alkaline alcoholic Congo red staining. Amyloid depositions were found in ...
Cholecystitis secondary to gallbladder localization of amyloidosis is very unusual. In conclusion, amyloidosis can rarely present as acute cholecystitis and there ...
by SP Neupane - ‎2016 - ‎Related articles
2 days ago - Skip to Article Content; Skip to Article Information. ×. Gallbladder amyloidosis: a unique histopathological finding FREE - In Google Play. VIEW.
A liver biopsy was performed, which was positive for amyloid deposits in the liver, ... carried out, which revealed gallstones and biliary sludge in the gallbladder.
by EP Misiakos - ‎Cited by 3 - ‎Related articles

ABSTRACT ONLY| VOLUME 49, SUPPLEMENT 1, S76-S77, FEBRUARY 01, 2017
Incidental finding of amyloidosis of the gallbladder
Vivienne Lea
Patricia Symons
Jim Yong
DOI:https://doi.org/10.1016/j.pathol.2016.12.199
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Amyloidosis may be systemic or localised, and is caused by extracellular deposits of amorphous, insoluble fibrillar proteins. We present two cases where vascular amyloidosis of the gallbladder was an incidental finding. The patients were a 79-year-old male and 53-year-old female who underwent elective laparoscopic cholecystectomy for cholelithiasis and choledocholithiasis respectively. In addition to the features of chronic cholecystitis, nodular hyaline material was noted in the walls of small and medium sized blood vessels on microscopy. This material stained with Congo red, with apple green birefringence on polarisation, consistent with amyloid. In both cases the amyloid resisted digestion with potassium permanganate, suggestive of primary amyloidosis. Amyloidosis of the gallbladder diagnosed after cholecystectomy is rare. To our knowledge, only nine cases have been reported in the literature. 1 Clinical presentation varies but may be asymptomatic, as in our cases. Gallbladder involvement has been reported in primary and secondary amyloidosis as well as familial amyloidosis. It is important that the clinician is informed when an incidental diagnosis of amyloidosis is made, as clinical work-up including looking for myeloma is mandatory.

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