fever, cutaneous erythematous plaques, and aseptic neutrophilic infiltration of various organs........................Evaluation of the Therapeutic Response by 11C-Methionine PET in a Case of Neuro-Sweet Disease

Evaluation of the Therapeutic Response by 11C-Methionine PET in a Case of Neuro-Sweet Disease:

Sweet disease is a multisystem inflammatory disorder characterized by fever, cutaneous erythematous plaques, and aseptic neutrophilic infiltration of various organs. Neuro-Sweet disease is a known rare central nervous system complication of Sweet disease. A 67-year-old Japanese woman who was diagnosed with neuro-Sweet disease underwent 11C-methionine (11C-MET) PET. 11C-MET PET revealed increased accumulation in the affected brain tissues. After steroid therapy, she became asymptomatic, and a follow-up 11C-MET PET scan showed disappearance of the abnormal uptake of 11C-MET. Received for publication March 25, 2020; revision accepted August 24, 2020. Conflicts of interest and sources of funding: none declared. Correspondence to: Yuka Yamamoto, MD, Department of Radiology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa 761-0793, Japan. E-mail: yuka@kms.ac.jp. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.