Patients with non-Hodgkin lymphoma (NHL) who are treated with rituximab may develop resistant disease, often associated with changes in expression of CD20. The next-generation β-particle–emitting radioimmunoconjugate 177Lu-lilotomab-satetraxetan (Betalutin) was shown to up-regulate CD20 expression in different rituximab-sensitive NHL cell lines and to act synergistically with rituximab in a rituximab-sensitive NHL animal model. We hypothesized that 177Lu-lilotomab-satetraxetan may be used to reverse...
Thu Oct 01, 2020 16:54
PET neuroimaging of amyloid-β (Aβ) provides an in vivo biomarker for pathologic changes associated with Alzheimer disease (AD). Aβ-targeted agents have been approved by the Food and Drug Administration, with additional agents, most notably targeting tau, currently under clinical investigation and one approved in May 2020. These agents, along with nonscintigraphic biomarkers from blood and cerebrospinal fluid, have provided an opportunity to investigate the pathogenesis, prodromal changes, and time...
Thu Oct 01, 2020 16:54
The aim of this work was to quantify the uptake of 18F-BMS-986192, a programmed cell death ligand 1 (PD-L1) adnectin PET tracer, in patients with non–small cell lung cancer. To this end, plasma input kinetic modeling of dynamic tumor uptake data with online arterial blood sampling was performed. In addition, the accuracy of simplified uptake metrics such as SUV was investigated. Methods: Data from a study with 18F-BMS-986192 in patients with advanced-stage non–small cell lung cancer eligible for...
Thu Oct 01, 2020 16:54
Thu Oct 01, 2020 16:54
Depth-encoding detectors with single-ended readout provide a practical, cost-effective approach for constructing high-resolution and high-sensitivity PET scanners. However, the current iteration of such detectors uses a uniform glass light-guide to achieve depth encoding, resulting in nonuniform performance throughout the detector array due to suboptimal intercrystal light sharing. We introduce Prism-PET, a single-ended-readout PET detector module with a segmented light-guide composed of an array...
Thu Oct 01, 2020 16:54
Thu Oct 01, 2020 16:54
Our objective was to assess the feasibility and accuracy of Cerenkov luminescence imaging (CLI) for assessment of surgical margins intraoperatively during radical prostatectomy. Methods: A single-center feasibility study included 10 patients with high-risk primary prostate cancer (PC). 68Ga-prostate-specific membrane antigen (PSMA) PET/CT scans were performed followed by radical prostatectomy and intraoperative CLI of the excised prostate. In addition to imaging the intact prostate, in the first...
Thu Oct 01, 2020 16:54
Prostate-specific antigen (PSA) is widely used to monitor treatment response in patients with metastatic castration-resistant prostate cancer. However, PSA measurements are considered only after 12 wk of treatment. We aimed to evaluate the prognostic value of early PSA changes after 177Lu-labeled prostate-specific membrane antigen (177Lu-PSMA) radionuclide treatment in metastatic castration-resistant prostate cancer patients. Methods: Men who were treated with 177Lu-PSMA under a compassionate-access...
Thu Oct 01, 2020 16:54
Thu Oct 01, 2020 16:54
Overexpression of somatostatin receptors (SSTRs) in patients with neuroendocrine neoplasms (NENs) is used for both diagnosis and treatment. Receptor density may reflect tumor differentiation and thus be associated with prognosis. Noninvasive visualization and quantification of SSTR density is possible by SSTR imaging (SRI) using PET. Recently, we introduced 64Cu-DOTATATE for SRI, and we hypothesized that uptake of this tracer could be associated with overall survival (OS) and progression-free survival...
Thu Oct 01, 2020 16:54
Radiopharmaceutical dosimetry depends on the localization in space and time of radioactive sources and requires the estimation of the amount of energy emitted by the sources deposited within targets. In particular, when computing resources are not accessible, this task can be performed using precomputed tables of specific absorbed fractions (SAFs) or S values based on dosimetric models. The aim of the OpenDose collaboration is to generate and make freely available a range of dosimetric data and tools....
Thu Oct 01, 2020 16:54
The overexpression of integrin αvβ6 in pancreatic cancer makes it a promising target for noninvasive PET imaging. However, currently, most integrin αvβ6–targeting radiotracers are based on linear peptides, which are quickly degraded in the serum by proteinases. Herein, we aimed to develop and assess a 68Ga-labeled integrin αvβ6–targeting cyclic peptide (68Ga-cycratide) for PET imaging of pancreatic cancer. Methods: 68Ga-cycratide was prepared, and its PET imaging profile was compared with that of...
Thu Oct 01, 2020 16:54
Publication date: October 2020Source: Journal of Cranio-Maxillofacial Surgery, Volume 48, Issue 10Author(s):
Thu Oct 01, 2020 17:54
Publication date: October 2020Source: Journal of Cranio-Maxillofacial Surgery, Volume 48, Issue 10Author(s):
Thu Oct 01, 2020 17:54
Publication date: October 2020Source: Journal of Cranio-Maxillofacial Surgery, Volume 48, Issue 10Author(s):
Thu Oct 01, 2020 17:54
Journal of Cutaneous Medicine and Surgery, Ahead of Print.
Thu Oct 01, 2020 09:24
Journal of Cutaneous Medicine and Surgery, Ahead of Print. BackgroundScabies is globally ubiquitous and is a significant health issue for institutions, the economically disenfranchised, resource-poor areas, and for those with weakened immune systems. Topicals are usually effective, but are cumbersome and expensive to use in large populations and for those nonadherent to topicals. Oral ivermectin became available in Canada for the off-label treatment of scabies in the fall 2018.ObjectivesTo review...
Thu Oct 01, 2020 09:25
Publication date: Available online 1 October 2020Source: Medical Mycology Case ReportsAuthor(s): Thana Thongsricome, Talerngsak Kanjanabuch, Nopparat Maeboonruen, Preeyarat Pavatung, Pisut Katavetin, Somchai Eiam-Ong
Thu Oct 01, 2020 18:17
Related Articles 125I Irradiation Stent for Hepatocellular Carcinoma with Main Portal Vein Tumor Thrombosis: A Systematic Review. Cardiovasc Intervent Radiol. 2020 Feb;43(2):196-203 Authors: Zhang L, Hu B, Li W, Huang P, Zhang S, Zhong BY, Ni CF Abstract A systematic review was conducted to provide an overview of the efficacy and safety of 125I irradiation stent placement for patients with hepatocellular carcinoma (HCC) and main portal vein...
Thu Oct 01, 2020 18:17
Prophylactic prednisolone for the prevention of early and intermediate adverse effects of radioactive iodine therapy in patients with thyroid cancer: study protocol for a single-centre, phase II/III, randomized, double-blinded, placebo-controlled clinical trial. Trials. 2020 Sep 29;21(1):812 Authors: Jayarajah U, Wijekoon M, Seneviratne SA Abstract BACKGROUND: Radioactive iodine (RAI) therapy is the standard adjuvant treatment for differentiated...
Thu Oct 01, 2020 18:17
Post-approval upper airway stimulation predictors of treatment effectiveness in the ADHERE registry.
Related Articles Post-approval upper airway stimulation predictors of treatment effectiveness in the ADHERE registry. Eur Respir J. 2019 01;53(1): Authors: Heiser C, Steffen A, Boon M, Hofauer B, Doghramji K, Maurer JT, Sommer JU, Soose R, Strollo PJ, Schwab R, Thaler E, Withrow K, Kominsky A, Larsen C, Kezirian EJ, Hsia J, Chia S, Harwick J, Strohl K, Mehra R, ADHERE registry investigators Abstract Upper airway stimulation (UAS) has been...
Thu Oct 01, 2020 18:19
Related Articles Effects of flavonoids on tongue squamous cell carcinoma. Cell Biol Int. 2020 Mar;44(3):686-720 Authors: Gutiérrez-Venegas G, Sánchez-Carballido MA, Delmas Suárez C, Gómez-Mora JA, Bonneau N Abstract Squamous cell carcinoma (SCC) of the tongue is associated with tobacco use, alcohol abuse, and human papillomavirus (HPV) infections. While clinical outcomes have recently improved for HPV-positive patients in general, 50% of patients...
Thu Oct 01, 2020 18:19
Related Articles Intracranial complications of pediatric rhinosinusitis: Identifying risk factors and interventions affecting length of hospitalization. Int J Pediatr Otorhinolaryngol. 2020 Apr;131:109841 Authors: Din-Lovinescu C, Mir G, Blanco C, Zhao K, Mazzoni T, Fried A, El Khashab M, Lin G Abstract OBJECTIVE: To identify risk factors and interventions affecting length of hospitalization (LOH) and clinical outcome in children with intracranial...
Thu Oct 01, 2020 18:19
Related Articles Associated syndromes in patients with Pierre Robin Sequence. Int J Pediatr Otorhinolaryngol. 2020 Apr;131:109842 Authors: Karempelis P, Hagen M, Morrell N, Roby BB Abstract OBJECTIVES: Classically, Pierre Robin Sequence (PRS) is a triad of micrognathia, glossoptosis, and airway obstruction, although frequently associated with cleft palate. Current literature reports that Stickler syndrome is the most common syndrome associated...
Thu Oct 01, 2020 18:19
Related Articles Respiratory and sleep characteristics based on frequency distribution of craniofacial skeletal patterns in Korean adult patients with obstructive sleep apnea. PLoS One. 2020;15(7):e0236284 Authors: Kim SJ, Ahn HW, Hwang KJ, Kim SW Abstract OBJECTIVE: To investigate the frequency distribution of various craniofacial skeletal patterns in a large Korean adult obstructive sleep apnea (OSA) population, and to find a relationship...
Thu Oct 01, 2020 18:19
Related Articles How do we teach surgical residents in the COVID-19 era? J Surg Educ. 2020 Sep - Oct;77(5):1005-1007 Authors: Okland TS, Pepper JP, Valdez TA Abstract OBJECTIVE: In response to ongoing concerns regarding transmission of the novel coronavirus (COVID-19), surgical practice has changed for the foreseeable future. Practice guidelines recommend only urgent or emergent surgical procedures be performed to minimize viral transmission....
Thu Oct 01, 2020 18:19
Mitoxantrone-Loaded Nanoparticles for Magnetically Controlled Tumor Therapy-Induction of Tumor Cell Death, Release of Danger Signals and Activation of Immune Cells. Pharmaceutics. 2020 Sep 27;12(10): Authors: Ratschker T, Egenberger L, Alev M, Zschiesche L, Band J, Schreiber E, Frey B, Derer A, Alexiou C, Janko C Abstract Stimulating the patient`s immune system represents a promising therapeutic strategy to fight cancer. However, low immunogenicity...
Thu Oct 01, 2020 18:19
Polysomnography and Nocturia Evaluations after Uvulopalatopharyngoplasty for Obstructive Sleep Apnea Syndrome. J Clin Med. 2020 Sep 25;9(10): Authors: Tsou YA, Chou EC, Shie DY, Lee MJ, Chang WD Abstract A higher incidence rate of nocturia in patients with obstructive sleep apnea (OSA) has been observed. We investigated the differences in clinical examinations between OSA patients with and without nocturia, and further compared those with...
Thu Oct 01, 2020 18:19
Chronic Facial Pain: Trigeminal Neuralgia, Persistent Idiopathic Facial Pain, and Myofascial Pain Syndrome-An Evidence-Based Narrative Review and Etiological Hypothesis. Int J Environ Res Public Health. 2020 Sep 25;17(19): Authors: Gerwin R Abstract Trigeminal neuralgia (TN), the most common form of severe facial pain, may be confused with an ill-defined persistent idiopathic facial pain (PIFP). Facial pain is reviewed and a detailed discussion...
Thu Oct 01, 2020 18:19
Induced Short-Term Hearing Loss due to Stimulation of Age-Related Factors by Intermittent Hypoxia, High-Fat Diet, and Galactose Injection. Int J Mol Sci. 2020 Sep 25;21(19): Authors: Park DJ, Ha S, Choi JS, Lee SH, Park JE, Seo YJ Abstract Age-related hearing loss (ARHL) is the most common sensory disorder among the elderly, associated with aging and auditory hair cell death due to oxidative-stress-induced mitochondrial dysfunction. Although...
Thu Oct 01, 2020 18:19
Efficient Delivery and Replication of Oncolytic Virus for Successful Treatment of Head and Neck Cancer. Int J Mol Sci. 2020 Sep 25;21(19): Authors: Hamada M, Yura Y Abstract Head and neck cancer has been treated by a combination of surgery, radiation, and chemotherapy. In recent years, the development of immune checkpoint inhibitors (ICIs) has made immunotherapy a new treatment method. Oncolytic virus (OV) therapy selectively infects tumor...
Thu Oct 01, 2020 18:19
Synthesis and Characterization of Citrate-Stabilized Gold-Coated Superparamagnetic Iron Oxide Nanoparticles for Biomedical Applications. Molecules. 2020 Sep 26;25(19): Authors: Stein R, Friedrich B, Mühlberger M, Cebulla N, Schreiber E, Tietze R, Cicha I, Alexiou C, Dutz S, Boccaccini AR, Unterweger H Abstract Surface-functionalized gold-coated superparamagnetic iron oxide nanoparticles (Au-SPIONs) may be a useful tool in various biomedical...
Thu Oct 01, 2020 18:19
Biofilm Growth Causes Damage to Silicone Voice Prostheses in Patients after Surgical Treatment of Locally Advanced Laryngeal Cancer. Pathogens. 2020 Sep 26;9(10): Authors: Spałek J, Deptuła P, Cieśluk M, Strzelecka A, Łysik D, Mystkowska J, Daniluk T, Król G, Góźdź S, Bucki R, Durnaś B, Okła S Abstract Voice prosthesis implantation with the creation of a tracheoesophageal fistula is the gold standard procedure for voice rehabilitation...
Thu Oct 01, 2020 18:19
Porcine Tracheal Mucosa-Derived Decellularized Patch to Prevent Septal Perforation in a Rabbit Model. Am J Rhinol Allergy. 2020 Sep 30;:1945892420961971 Authors: Kim SJ, Jung SY, Lee MJ, Bae JH, Kim HS Abstract BACKGROUND: Nasal septal perforation is caused by bilateral septal mucosal injuries resulting from nasal trauma and septal surgeries. Previous studies have reported that biocompatible materials may be effective for repairing nasal...
Thu Oct 01, 2020 18:19
The Aging Physician and Surgeon. Ear Nose Throat J. 2020 Sep 29;:145561320944297 Authors: Sataloff RT, Hawkshaw M, Kutinsky J, Maitz EA Abstract BACKGROUND: As the population of aging physicians increases, methods of assessing physicians' cognitive function and predicting clinically significant changes in clinical performance become increasingly important. Although several approaches have been suggested, no evaluation system is accepted...
Thu Oct 01, 2020 18:19
Treatment response lowers tumor symptom burden in recurrent and/or metastatic head and neck cancer. BMC Cancer. 2020 Sep 29;20(1):933 Authors: Hecht M, Hahn D, Wolber P, Hautmann MG, Reichert D, Weniger S, Belka C, Bergmann T, Göhler T, Welslau M, Große-Thie C, Guntinas-Lichius O, von der Grün J, Balermpas P, Orlowski K, Messinger D, Stenzel KG, Fietkau R Abstract BACKGROUND: Head and neck squamous cell cancer (HNSCC) frequently causes...
Thu Oct 01, 2020 18:19
Using machine learning of clinical data to diagnose COVID-19: a systematic review and meta-analysis.
Using machine learning of clinical data to diagnose COVID-19: a systematic review and meta-analysis. BMC Med Inform Decis Mak. 2020 Sep 29;20(1):247 Authors: Li WT, Ma J, Shende N, Castaneda G, Chakladar J, Tsai JC, Apostol L, Honda CO, Xu J, Wong LM, Zhang T, Lee A, Gnanasekar A, Honda TK, Kuo SZ, Yu MA, Chang EY, Rajasekaran MR, Ongkeko WM Abstract BACKGROUND: The recent Coronavirus Disease 2019 (COVID-19) pandemic has placed severe...
Thu Oct 01, 2020 18:19
Neutrophils mediated multistage nanoparticle delivery for prompting tumor photothermal therapy. J Nanobiotechnology. 2020 Sep 29;18(1):138 Authors: Ye B, Zhao B, Wang K, Guo Y, Lu Q, Zheng L, Li A, Qiao J Abstract BACKGROUND: Neutrophil-based drug delivery system possesses excellent advantages in targeting at tumour because neutrophils are easily recruited by chemotactic factor in tumor microenvironment. Herein, we developed a novel tactic...
Thu Oct 01, 2020 18:19
Efficacy and safety of paranasal sinus balloon catheter dilation in pediatric chronic rhinosinusitis: a systematic review. J Otolaryngol Head Neck Surg. 2020 Sep 29;49(1):69 Authors: Mirza AA, Shawli HY, Alandejani TA, Aljuaid SM, Alreefi M, Basonbul RA, Alhomaiani SK, Althobaity BA, Alhumaidi DA, Zawawi F Abstract OBJECTIVE: Chronic rhinosinusitis (CRS) negatively affects quality of life (QoL), and balloon catheter sinuplasty (BCS) has...
Thu Oct 01, 2020 18:19
Response evaluation of cervical lymph nodes after chemoradiation in patients with head and neck cancer - does additional [18F]FDG-PET-CT help? Cancer Imaging. 2020 Sep 29;20(1):69 Authors: Dejaco D, Uprimny C, Widmann G, Riedl D, Moser P, Arnold C, Steinbichler TB, Kofler B, Schartinger VH, Virgolini I, Riechelmann H Abstract BACKGROUND: Contrast-enhanced high-resolution computed tomography (contrast-CT) is a standard imaging modality...
Thu Oct 01, 2020 18:19
A prickly situation: an attempted Caterpillar ingestion - case report. J Otolaryngol Head Neck Surg. 2020 Sep 29;49(1):70 Authors: Bhardwaj AK, Fnais N, Chin CJ Abstract BACKGROUND: Foreign body ingestion is a common problem in pediatrics. Each foreign body can present its' own unique challenges during removal, and we present the management of an ingested Spotted Tussock Moth (Lophocampa maculata), more commonly known as a caterpillar....
Thu Oct 01, 2020 18:19
Improving peri-operative psychosocial interventions for children with autism spectrum disorder undergoing ENT procedures. J Laryngol Otol. 2020 Sep 30;:1-7 Authors: Fahy R, Corbett M, Keogh I Abstract OBJECTIVES: Children with autism spectrum disorder face a broad range of communication and sensory challenges. Many of these children also have chronic ENT issues. This study aims to better understand these challenges and improve our services...
Thu Oct 01, 2020 18:19
Nanosized-Ag-doped porous β-tricalcium phosphate for biological applications. Mater Sci Eng C Mater Biol Appl. 2020 Sep;114:111037 Authors: Yuan J, Wang B, Han C, Huang X, Xiao H, Lu X, Lu J, Zhang D, Xue F, Xie Y Abstract The treatment of infectious or potentially infective bone defects remains a major problem in clinical practice. Silver has the ability to potentiate antibiotics against resistant bacterial strains. In order to reduce...
Thu Oct 01, 2020 18:19
Is sarcopenia a predictor of prognosis for patients undergoing radiotherapy for head and neck cancer? A meta-analysis. Clin Nutr. 2020 Sep 18;: Authors: Findlay M, White K, Stapleton N, Bauer J Abstract INTRODUCTION: Computed tomography (CT)-defined sarcopenia is a demonstrated poor prognostic factor for survival in patients with cancer, however, its impact in patients with head and neck cancer (HNC) has only recently been explored. This...
Thu Oct 01, 2020 18:19
Reply to Dr. Alberto Deganello. Auris Nasus Larynx. 2020 Sep 26;: Authors: Eguchi K PMID: 32994075 [PubMed - as supplied by publisher]
Thu Oct 01, 2020 18:19
Effectiveness of intraoperative facial nerve monitoring and risk factors related to postoperative facial nerve paralysis in patients with benign parotid tumors: A 20-year study with 902 patients. Auris Nasus Larynx. 2020 Sep 26;: Authors: Kinoshita I, Kawata R, Higashino M, Nishikawa S, Terada T, Haginomori SI Abstract OBJECTIVE: We examined the incidence, risk factors, and recovery time for postoperative facial nerve paralysis in patients...
Thu Oct 01, 2020 18:19
Utility of teledermatopathology for intraoperative margin assessment of melanoma in situ, lentigo maligna type: A 6 year community practice experience. Eur J Surg Oncol. 2020 Sep 22;: Authors: Emanuel PO, Patel R, Zwi J, Cheng D, Izzard M Abstract BACKGROUND: Achieving negative margins for melanoma in situ, lentigo maligna type can be challenging, particularly on cosmetically sensitive areas. OBJECTIVE: To assess the utility...
Thu Oct 01, 2020 18:19
Evaluation of the efficacy of low concentration fluoride gel using custom trays to prevent radiation-related dental caries in patients with head and neck cancer: protocol for a randomised controlled phase III trial (FluCar study). BMJ Open. 2020 Sep 29;10(9):e038606 Authors: Sakiko S, Yanamoto S, Murata M, Kawashita Y, Yoshimatsu M, Funahara M, Umeda M, Saito T Abstract INTRODUCTION: The present study is a randomised, multicentre, open-label,...
Thu Oct 01, 2020 18:19
Meter enhances the subcortical processing of speech sounds at a strong beat. Sci Rep. 2020 Sep 29;10(1):15973 Authors: Moon IJ, Kang S, Boichenko N, Hong SH, Lee KM Abstract The temporal structure of sound such as in music and speech increases the efficiency of auditory processing by providing listeners with a predictable context. Musical meter is a good example of a sound structure that is temporally organized in a hierarchical manner,...
Thu Oct 01, 2020 18:19
Quality measures in cervical lymphadenectomy for cutaneous malignancy by head and neck trained general surgeons. N Z Med J. 2020 Aug 21;133(1520):50-60 Authors: Nahab F, Ollek S, Harman R, Martin R Abstract AIM: Therapeutic lymphadenectomy remains the gold standard for surgical management of clinically evident regional cervical disease for cutaneous malignancy. However, international consensus on adequate lymphadenectomy is lacking. Attempts...
Thu Oct 01, 2020 18:19
Spontaneous atraumatic lingual haematoma presenting with threatened airway obstruction. N Z Med J. 2020 Aug 21;133(1520):120-124 Authors: Patel CB, Benamira L, Chaplin J Abstract Spontaneous bleeding in the head and neck region is exceedingly rare, particularly in the absence of trauma or an underlying disorder. We describe a case of an atraumatic lingual haematoma in an 88-year-old male presenting with threatened airway obstruction. The...
Thu Oct 01, 2020 18:19
Efficacy of stress management program for depressive patients with advanced head and neck cancer: A single-center pilot study. Int J Clin Health Psychol. 2020 Sep-Dec;20(3):213-221 Authors: Ichikura K, Nakayama N, Matsuoka S, Ariizumi Y, Sumi T, Sugimoto T, Fukase Y, Murayama N, Tagaya H, Asakage T, Matsushima E Abstract Background/Objective: Patients with head and neck cancer (HNC) have some problems such as dysfunction of breathing,...
Thu Oct 01, 2020 18:19
Calcitonin gene-related peptide: A promising bridge between cancer development and cancer-associated pain in oral squamous cell carcinoma. Oncol Lett. 2020 Nov;20(5):253 Authors: Zhang Y, Lin C, Wang X, Ji T Abstract Nerves have been widely demonstrated to exert major effects in tumor-associated microenvironments. Due to the characteristic innervation of the oral cavity and the fact that cancer-associated pain is a distinct feature of...
Thu Oct 01, 2020 18:19
Flat sticker as a mobile airway foreign body: A case report and review of the literature. Radiol Case Rep. 2020 Nov;15(11):2391-2395 Authors: Wineski RE, Panico EC, Bailey LN, Cardenas AM, Grayson JW, Wiatrak BJ Abstract Diagnosis of an airway foreign body in the setting of an unwitnessed aspiration event remains a challenge for physicians in the emergency setting. We describe a case of a 2-year-old male who presented to the emergency...
Thu Oct 01, 2020 18:19
Accessory submaxillary gland: Two new case reports and a literature review. J Clin Exp Dent. 2020 Sep;12(9):e892-e895 Authors: Torres-Gaya J, Marqués-Mateo M, Dualde-Beltrán D, Sada-Malumbres Á, García-San Segundo MDM, Puche-Torres M Abstract Background: The accessory submaxillary gland is a very uncommon anatomical variant, and incidence in the general population has not yet been quantified. The presence of pathology in these glands is...
Thu Oct 01, 2020 18:19
Reconstruction of facial dermatofibrosarcoma protuberans using an anterolateral thigh flap: a case report and literature review. J Surg Case Rep. 2020 Sep;2020(9):rjaa340 Authors: Besharah BO, Ghazzawi RA, Al-Kaff HH, Abdelmonim SK, Al-Essa MA Abstract Dermatofibrosarcoma protuberans is a rare, locally aggressive cutaneous malignancy with a high rate of recurrence if the head-and-neck region is involved. Treatment is challenging as it...
Thu Oct 01, 2020 18:19
A systematic review of home-based dietary interventions during radiation therapy for cancer. Tech Innov Patient Support Radiat Oncol. 2020 Dec;16:10-16 Authors: Allenby TH, Crenshaw ML, Mathis K, Champ CE, Simone NL, Schmitz KH, Tchelebi LT, Zaorsky NG Abstract Purpose: Our objectives are to assess (1) the acceptability and feasibility of dietary interventions for patients undergoing radiation therapy (RT), and (2) the impact of dietary...
Thu Oct 01, 2020 18:19
[Liquid biopsy-a possible key player in immuno-oncology]. HNO. 2020 Sep 29;: Authors: Wallesch M, Wirth M, Wollenberg B Abstract BACKGROUND: Clinical application of immune checkpoint inhibitors (ICI), whether as monotherapy or in combination with established methods, is revolutionizing treatment of head and neck cancer. However, this change in therapeutic concepts requires reevaluation and further development of predictive and prognostic...
Thu Oct 01, 2020 18:19
[The microbiome in head and neck tumors-initial findings and outlook]. HNO. 2020 Sep 29;: Authors: Lang S, Brandau S, Marchesi JR, Jablonska J, Thurnher D, Mattheis S, Buer J, Hussain T Abstract Technical progress in molecular biology has allowed for a more detailed analysis of the composition of the human microbiome in recent years. Inter- and intraindividual differences in microbiome composition have been demonstrated, which in part...
Thu Oct 01, 2020 18:19
Assessment of functional and aesthetic outcomes in septorhinoplasty. Eur Arch Otorhinolaryngol. 2020 Sep 29;: Authors: Simsek T, Erdoğan MM, Özçetinkaya Erdoğan S, Kazaz H, Tezcan E, Seyhan S Abstract PURPOSE: The aim of this study is to review the aesthetic and functional outcomes of septorhinoplasty using questionnaires that have never been collectively used, as well as surgeons' evaluation. MATERIALS AND METHODS: Our study...
Thu Oct 01, 2020 18:19
OSA in patients with head and neck cancer is associated with cancer size and oncologic outcome. Eur Arch Otorhinolaryngol. 2020 Sep 29;: Authors: Huppertz T, Horstmann V, Scharnow C, Ruckes C, Bahr K, Matthias C, Gouveris H Abstract PURPOSE: Obstructive sleep apnea (OSA) is associated with severe daytime sleepiness and reduced quality of life. These symptoms are also present in patients with squamous cell carcinoma of the head and neck...
Thu Oct 01, 2020 18:19
Time interval between (chemo)radiotherapy and subsequent laryngectomy is not prognostic for post operative complications and survival. Eur Arch Otorhinolaryngol. 2020 Sep 29;: Authors: Pézier TF, Rijken JA, Tijink BM, Braunius WW, de Bree R Abstract PURPOSE: Pharyngocutaneous fistula (PCF) formation and swallowing difficulties are common and troublesome complications following total laryngectomy (TL). Prior (chemo)radiotherapy ((C)RT)...
Thu Oct 01, 2020 18:19
Impact of early nutrition counseling in head and neck cancer patients with normal nutritional status. Support Care Cancer. 2020 Sep 29;: Authors: Ho YW, Yeh KY, Hsueh SW, Hung CY, Lu CH, Tsang NM, Wang HM, Hung YS, Chou WC Abstract BACKGROUND: Nutritional counseling is frequently overlooked in cancer patients with normal nutritional status. This study aimed to evaluate the impact of nutritional counseling in head and neck cancer (HNC)...
Thu Oct 01, 2020 18:19
Phase II trial of combination treatment with S-1/cetuximab in patients with platinum-ineligible recurrent and/or metastatic squamous cell carcinoma of the head and neck. Int J Clin Oncol. 2020 Sep 29;: Authors: Taguchi J, Shimizu Y, Ariga S, Goda T, Ohhara Y, Honma R, Noguchi T, Takeuchi S, Kinoshita I, Amano T, Mizumachi T, Kano S, Takahara M, Abe T, Homma A, Dosaka-Akita H Abstract BACKGROUND: The standard of care for first-line treatment...
Thu Oct 01, 2020 18:19
Endoscopic transoral nasopharyngectomy. Head Neck. 2020 Sep 30;: Authors: Soriano RM, Rindler RS, Helman SN, Pradilla G, Solares CA Abstract BACKGROUND: A minimal access technique for the management of nasopharyngeal tumors extending below the palatal plane and laterally beyond the pterygoid musculature is yet to be developed. In this study we demonstrate the feasibility of endoscopic transoral nasopharyngectomy (ETON) for resection of...
Thu Oct 01, 2020 18:19
Impact of age and comorbidity on survival among patients with oral cavity squamous cell carcinoma. Head Neck. 2020 Sep 30;: Authors: Patel KB, Martin D, Zhao S, Kumar B, Carrau R, Ozer E, Agrawal A, Kang S, Rocco JW, Schuller D, Teknos T, Brock G, Old M Abstract OBJECTIVE: To identify predictors of overall survival (OS) and to stratify patients according to significant prognostic variables. METHODS: A retrospective study of 274...
Thu Oct 01, 2020 18:19
Radical external beam re-irradiation in the treatment of recurrent head and neck cancer: Critical review. Head Neck. 2020 Sep 30;: Authors: Svajdova M, Dubinsky P, Kazda T Abstract Management of patients with recurrent head and neck cancer remains a challenge for the surgeon as well as the treating radiation oncologist. Even in the era of modern radiotherapy, the rate of severe toxicity remains high with unsatisfactory treatment results....
Thu Oct 01, 2020 18:19
The predictive value of photogrammetry for obstructive sleep apnea. J Clin Sleep Med. 2020 Sep 30;: Authors: He S, Li Y, Xu W, Kang D, Li H, Wang C, Ding X, Han D Abstract STUDY OBJECTIVES: The aim of this study was to develop a prediction model for obstructive sleep apnea (OSA) based on photographic measurements of upper airway structures and to compare this to the model based on general physical examination. METHODS: Participants...
Thu Oct 01, 2020 18:19
Vitamin D oral gel for prevention of radiation-induced oral mucositis: a randomized clinical trial. Oral Dis. 2020 Sep 28;: Authors: Bakr IS, Zaki AM, El-Moslemany RM, Elsaka RO Abstract OBJECTIVES: The aim of this clinical trial is to evaluate the effectiveness of topical oral vitamin D gel in prevention of radiation induced oral mucositis. MATERIAL AND METHODS: A three-armed randomized controlled clinical trial on forty-five...
Thu Oct 01, 2020 18:19
Evaluation of Inhibitory Effects of Caffeine on Human Carcinoma Cells. Nutr Cancer. 2020 Sep 30;:1-5 Authors: Tonkaboni A, Lotfibakhshaiesh N, Danesh P, Tajerian R, Ziaei H Abstract One of the world's most consumed medications is caffeine which is available in the vast majority of beverages. Previously, some effects of caffeine have been evaluated including its inhibitory effect on cancer cells. But, the influence of caffeine on esophagus...
Thu Oct 01, 2020 18:19
Childhood Exposure to Low-Moderate Doses of Ionizing Radiation and the Risk of Vascular Diseases -The Tinea Capitis Study. Am J Epidemiol. 2020 Sep 30;: Authors: Sadetzki S, Chetrit A, Boursi B, Luxenburg O, Novikov I, Cohen A Abstract The Tinea Capitis Study, Israel, 1966-2011 We assessed the association between childhood exposure to low-moderate doses of ionizing radiation (IR) to the head and neck and the development of vascular diseases...
Thu Oct 01, 2020 18:19
Tumor microenvironment characterization in head and neck squamous carcinoma reveals distinct genomic alterations and clinical outcomes. Clin Transl Med. 2020 Sep;10(5):e187 Authors: Shi R, Bao X, Sun J, Lu S, Belka C, Li M PMID: 32997410 [PubMed - as supplied by publisher]
Thu Oct 01, 2020 18:19
Pharyngoesophageal Segment Distention Across Volumes and Pathology. J Speech Lang Hear Res. 2020 Sep 30;:1-6 Authors: Logan AM, Gawlik AE, Aden JK, Jarvis NC, Dion GR Abstract Purpose Patients receive multiple bolus trials during a videofluoroscopic swallowing study (VFSS) to assess swallow function, inclusive of narrowing within the pharyngoesophageal segment (PES). While differences in the narrowest and widest segments are visualized,...
Thu Oct 01, 2020 18:19
The Effect of Photobiomodulation on Nitrite and Inflammatory Activity in Radiotherapy-Induced Oral Mucositis: A Randomized Clinical Trial. Lasers Surg Med. 2020 Sep 30;: Authors: Martins AFL, Morais MO, Sousa-Neto SS, Oton-Leite AF, Pereira CH, Valadares MC, Freitas NMA, Batista AC, Leles CR, Mendonça EF Abstract BACKGROUND AND OBJECTIVES: To investigate pro- and anti-inflammatory cytokines and nitrite salivary levels in patients with...
Thu Oct 01, 2020 18:19
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