Angioedema to patent blue dye in breast surgery

Angioedema to patent blue dye in breast surgery: A case report and review of literatures: Hsuan-Cheng Wu, Jyh-Cherng Yu, Lin-Chi Yi, Cheng-Shan Wu, Shu-Chuan Lin, Zhi-Fu Wu



Journal of Medical Sciences 2019 39(1):43-48



Patent blue is the safest and most widely available blue dye for lymphatic mapping during breast cancer and cervical cancer surgeries. This paper reports an anaphylactic reaction to patent blue used for lymphatic mapping during breast cancer surgery where the patient presented with angioedema with bilateral eyelid and upper airway edema. Anesthesiologists should be aware of the possibility of anaphylactic reactions to any drug or substance administered during surgery.