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Κυριακή 17 Ιουλίου 2022

Autogenous Bone Block versus Collagenated Xenogeneic Bone Block in the reconstruction of the atrophic alveolar ridge: a non‐inferiority randomized clinical trial

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Abstract

Objective

To compare the efficacy of equine derived collagenated bone blocks (CXBB) and autogenous bone block (ABB) for lateral alveolar ridge augmentation and two-stage implant placement.

Materials and methods

Sixty-four patients with tooth gaps up to 4 teeth and atrophic alveolar ridges with ≤ 4 mm were randomly assigned to lateral augmentation using CXBB or ABB. Lateral bone thickness was measured 2 mm below the alveolar crest at augmentation surgery and 30 weeks later at implant placement. Implant related outcomes, adverse events, surgery duration, pain sensation, analgesic consumption and oral health-related quality of life were also assessed. Data was analyzed using Fisher's exact, Mann–Whitney, and Wilcoxon signed-rank tests.

Results

At 30 weeks, the median change in lateral bone thickness amounted to 2.90 (CXBB) and 3.00 (ABB), respectively. Secondary endpoints demonstrated similar results for CXBB and ABB in terms of possibility to place an implant, need to perform a secondary bone augmentation at implant placement and rate of complications. Early implant failure was 20% for CXBB and 10% for ABB, with no difference between the groups. Pain scores and postoperative consumption of analgesics were significantly lower in the CXBB group than in the ABB group, especially during the first days post-surgery.

Conclusion

CXBB is non-inferior to ABB for horizontal alveolar ridge augmentation and two-stage implant placement.

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