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Τρίτη 28 Ιουνίου 2022

Pediatric and Adolescent COVID‐19 Vaccination Side Effects: A Retrospective Cohort Study of Iranian Teenage group in 2021

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Abstract

Background

To determine the safety and efficacy profile of teenager COVID-19 vaccination.

Methods

In this retrospective cohort study, contact numbers of parents of teenagers under 18 years of age referred to a teenager vaccination centers in Tehran-Iran to receive the corona vaccine were collected and following information were obtained via the phones:demographic information, type of vaccine and number of doses received, and additional information,like complications, required treatments.

Results

11,042 subjects aged 10-18 years, mean age 14.55±1.83years, including 5374 boys and 5768 girls were investigated. 88.1% received the Sinopharm and 11.9% the Soberana vaccine. General side effects, including fatigue, fever and chills, injection site painand dizziness, etc. happened in 2978 cases, 7421 children presented with at least one general or organ-specific side effect following vaccination, including potentially critical side effects,such as vascu lar injuries, respiratory complication, etc.0.1% of the subject needed hospital admission. The breakthrough infection happened in 200 individuals.

Conclusion

Our study shows that Sinopharm and Soberana (PastoCoVac) COVID-19 vaccine are generally safe with no serious side effects in fewer than 18 years old. COVID19 infection and reinfection can occur after vaccination, but the incidence is actually tolerable and significantly lower than in the unvaccinated group.

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