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Κυριακή 26 Σεπτεμβρίου 2021

3D Real IR MR Findings in Acoustic Neuromas: Altered Perilymph Metabolism

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Ear Nose Throat J. 2021 Sep 24:1455613211047124. doi: 10.1177/01455613211047124. Online ahead of print.

ABSTRACT

OBJECTIVES: This study aimed to investigate the perilymph metabolism by analyzing the 3D real IR MR findings in acoustic neuroma (AN) after intravenous administration of gadolinium (Gd).

METHODS: Eleven patients (6 men and 5 women) diagnosed with AN were included, and 3D real IR MRI was performed 4 hours after intravenous Gd injection. The signal intensity a nd details of inner ear, tumor, and internal auditory canal (IAC) by MRI were analyzed.

RESULTS: Four patients had tumors confined to the IAC, and 5 had tumors that extended to the cerebellopontine angle cistern. The signal intensity of the cochlea, vestibule, and IAC fundus was conspicuously enhanced in 3D real IR images than the control side. One patient had a tumor in the cochlea, in which the signal intensity of the semicircular canal and vestibule was increased. One patient had an intravestibular tumor in which the signal intensity of the semicircular canal was increased and the cochlea had endolymphatic hydrops in the affected ear.

CONCLUSIONS: The synchronously increased signal intensity in the inner ear and IAC may indicate that IAC may serve as a channel for removal of the perilymph in the inner ear; the blockage by the tumor may have changed the hydrodynamics of the perilymph to cause a longer retention of Gd in the inner ear.

PMID:34560831 | DOI:10.1177/01455613211047124

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