Magnetic Resonance Imaging Signal Changes Mimicking Bone Metastasis in Patients Receiving Bisphosphonate Therapy

xlomafota13 shared this article with you from Inoreader Magnetic Resonance Imaging Signal Changes Mimicking Bone Metastasis in Patients Receiving Bisphosphonate Therapy Via Mol Imaging Radionucl Ther Mol Imaging Radionucl Ther. 2021 Jun 3;30(2):122-125. doi: 10.4274/mirt.galenos.2020.49091. ABSTRACT Bisphosphonates are inorganic pyrophosphate agents that reduce bone turnover. These agents reduce bone pain and delay skeletal complications, such as fractures in patients with metastatic lytic lesions, malignant-related hypercalcemia, multiple myeloma, Paget's disease of bone, and osteoporosis. Osteonecrosis, developing in the jaw bones specifically, has been described as a complication associated with the use of bisphosphonates. In this report, we presented osteonecrosis-like magnetic resonance imaging findings that can be confused with bone metastasis in two patients who underwent long-term bisphosphonate treatment and the value of bone scan and 18flor-fluorodeoxyglucose positron emission tomography/computerized tomography in the differential diagnosis. PMID:34082517 | DOI:10.4274/mirt.galenos.2020.49091 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.