Eltrombopag-related renal vein thromboembolism in a patient with immune thrombocytopenia: A case report

paythelady.612 shared this article with you from Inoreader Eltrombopag-related renal vein thromboembolism in a patient with immune thrombocytopenia: A case report Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Apr 16;9(11):2611-2618. doi: 10.12998/wjcc.v9.i11.2611. ABSTRACT BACKGROUND: Eltrombopag is an orally administered thrombopoietin receptor agonist linked to a heightened risk of treatment-related thromboembolism. Both venous and arterial thromboses have been documented in the medical literature. CASE SUMMARY: In the absence of nephropathy, a 48-year-old patient receiving eltrombopag for immune thrombocytopenia (ITP) developed renal vein thrombosis and pulmonary embolism. The renal vein thrombus spontaneously resolved during subsequent anticoagulant treatment, restoring venous circulation. CONCLUSION: A rapid upsurge in platelets, rather than their absolute number, may trigger thrombotic events in this setting. For patients at high thrombotic risk, individualized eltrombopag dosing and vigilance in platelet monitoring are perhaps needed during treatment of ITP. PMID:33889627 | PMC:PMC8040189 | DOI:10.12998/wjcc.v9.i11.2611 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.